Multiple Myeloma
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
FGFR3,
CCND1,
CRBN,
IRF4,
KRAS,
NRAS,
BRAF,
CDKN2A,
TNFRSF13B,
CBX7,
LIG4,
BCL2,
MYC,
MUC1,
MCL1,
CSF3,
IL6,
ULK4,
PSORS1C2,
PARP1,
MIR19A,
CCL2,
BCL2L1,
PTHLH,
NQO1,
GSTT1,
CDKN2C,
CD86,
HSPB1,
EPHX1
FGFR3,
CCND1,
CRBN,
IRF4,
KRAS,
NRAS,
BRAF,
CDKN2A,
TNFRSF13B,
CBX7,
LIG4,
BCL2,
MYC,
MUC1,
MCL1,
CSF3,
IL6,
ULK4,
PSORS1C2,
PARP1,
MIR19A,
CCL2,
BCL2L1,
PTHLH,
NQO1,
GSTT1,
CDKN2C,
CD86,
HSPB1,
EPHX1,
BNIP3,
HLA-A,
SPARC,
SOD2,
CSF2,
PRAME,
BIRC3,
KDM6A,
NUAK1,
IFNA2,
MIR92A1,
MAF,
BTG1,
IKZF1,
TP53,
B2M,
PIK3CA,
KMT2D,
CDK4,
PVT1,
PCAT1,
POU5F1,
ELL2,
HRAS,
FOPNL,
PTPN11,
LPP,
IDH2,
PREX1,
IDH1,
CDCA7L,
KLF2,
GBA,
CDH12,
MAPK1,
RPL36P20,
NR3C1,
LRRC31,
LRRC34,
CAMKMT,
ACOXL-AS1,
PIK3CG,
PIK3CD,
HGF,
PIK3CB,
PTEN,
MTOR,
ABCB1,
PTPRC,
MIR15A,
FN1,
CD44,
CD40,
CD38,
CD34,
MIR21,
GRAMD1B,
EZH2,
MIR29B1,
MIR29B2,
CCL3,
SDC1,
DTNB,
CDKN2B,
MALAT1,
IL1B,
RNF165,
IFNG,
MIR4435-2HG,
IGF1,
IGH,
CIB3,
IL10,
CTAG1B,
MS4A1,
PSORS1C1,
CTNNB1,
KIT,
JAK2,
CEP120,
GGNBP1,
MDM2,
DNER,
MET,
BMF,
NCAM1,
NCK1,
CKS1B,
LCOR,
ANKRD27,
DIO1,
TNFRSF11B,
HSP90AA1,
LRRIQ4,
HLA-B,
HIF1A,
ATN1,
CXCL12,
H3P10,
CD19,
TNFSF11,
PPT2,
MSC,
MYOM2,
CACNG4,
TNFSF10,
ATP6V0E1P2,
DNAH11,
SOCS1,
MYNN,
VEGFA,
CD274,
NCAPH2,
CDR3,
BAK1,
CXCR4,
TNFRSF17,
XBP1,
PPT2-EGFL8,
ABCG2,
ANXA5,
SMUG1,
ATG5,
HPSE,
SRCAP,
CHEK2,
TNFSF13B,
SP140,
IKZF3,
KLRK1,
TRIM13,
DKK1,
AKT1,
TOM1,
ALB,
HDAC6,
TBC1D9,
MED24,
HDAC9,
CASC19,
NSD2,
SLAMF7,
BTK,
ACOXL,
USP8P1,
TNF,
CALM1,
WAC,
SP3,
CALM2,
CALM3,
KLRC4-KLRK1,
KRIT1,
CCHCR1,
RFWD3,
KRT20,
CASR,
CASP3,
SMARCD3,
STAT3,
MAPK3,
SPG7,
ARR3,
TNFSF13,
IL6R,
CTAG1A,
PRKAR1A,
FAS,
NR1I3,
RTEL1,
CXADR,
CXCL8,
MAPK8,
TRAF3,
ERN1,
FGF2,
SOST,
CXADRP1,
XPO1,
XBP1P1,
IL6ST,
MIR34A,
SUB1,
NFKB1,
MAFB,
MIR221,
PCNA,
RB1,
ABCC1,
ANOS1,
BSG,
CCND2,
IL17A,
BCL6,
MKKS,
MIR20A,
LOC102724971,
EPO,
ICAM1,
MRPL28,
LRPPRC,
EIF4E,
PTK2B,
EPHB2,
AICDA,
SPP1,
H3P9,
VCAM1,
IFNA1,
MTHFR,
IFNA13,
NXT1,
MAPK14,
STOML2,
CDK6,
COL11A2,
LOC102723407,
IL4,
PAX5,
PRDM1,
NM,
PWWP3A,
CD200,
HSP90B1,
PDCD1,
MME,
SOAT1,
NOTCH1,
AHSA1,
OSM,
AIMP2,
MIR155,
ANP32B,
RBM45,
VDR,
PTGS2,
BRD4,
TENT5C,
GRAP2,
HSPA5,
RNF19A,
HMMR,
TP73,
IL2,
IL3,
INA,
WWOX,
HAS1,
DIS3,
POLDIP2,
PIM2,
MIR17HG,
CCND3,
ANXA2,
CRK,
BCR,
CD28,
BMI1,
CD80,
CD9,
ACTB,
APEX1,
CASP8,
CTLA4,
CD81,
CDKN1B,
RUNX2,
IL15,
IL16,
FRZB,
GSTP1,
CD47,
CUX1,
SCT,
IL11,
CD40LG,
GGPS1,
CTRL,
CRP,
NEDD8,
SELPLG,
GPRC5D,
IGF1R,
IGHV3-69-1,
MIP,
SPA17,
CFLAR,
MMP2,
NEAT1,
TGFB1,
ANGPTL1,
GDE1,
LDLRAP1,
CCDC54,
CCR1,
LRP1,
MYD88,
SLC7A5,
ITGB1,
KDR,
COMMD3-BMI1,
SGSM3,
BMP2,
MIR17,
DCLRE1C,
PTPN6,
MAP2K7,
ZHX2,
DEPTOR,
EGFR,
EIF4G1,
MIR19B1,
FOXP3,
MIR203A,
JAG1,
CD226,
TNFRSF11A,
JAK1,
VCAN,
NEK2,
IL32,
MIR214,
IL1RL1,
CD79B,
SLC5A5,
TICAM2,
TIMP2,
MIR210,
PIM1,
IGHV3OR16-7,
NR2F2,
ITGA4,
DCTN6,
H3P23,
SMR3B,
MARCKSL1,
PTP4A3,
HDAC3,
B3GAT1,
IFI27,
JAG2,
MMP9,
BCL10,
MSH3,
HSPA4,
NR0B2,
HSF1,
IGL,
MIR135B,
PSMD9,
TNFRSF13C,
NFKBIA,
NFKB2,
CDH1,
TERT,
SET,
ARHGAP24,
FCRL5,
GFI1,
GEM,
MIR137,
MVP,
MIR16-1,
PITX2,
PF4,
KLRC1,
FLT4,
EGF,
ACTR1A,
CDKN1A,
ARFRP1,
MIR152,
SPRY2,
MBL2,
FRA16D,
TMED7,
GLI1,
PMAIP1,
GNA12,
PPARG,
CASP9,
APAF1,
MDM4,
LGALS1,
ZNRD2,
TRAF6,
DAP,
RPSA,
LINC01194,
APOBEC2,
GRN,
SART3,
VCP,
WLS,
UCA1,
TMED7-TICAM2,
ABL1,
COX8A,
BMP6,
TFRC,
LY9,
CR2,
TLR4,
CXCR5,
TRIAP1,
MICA,
JUN,
TRPV2,
TXN,
UBE2I,
CD82,
TYMS,
ITGA5,
PARP14,
PTPRA,
PCDH10,
PRKN,
HAMP,
PDK1,
IL21,
RAF1,
CD276,
CDK9,
SPANXA2,
RAC1,
PVR,
CD79A,
KLF6,
CDK2,
PTGS1,
POU2AF1,
POU2F2,
EPHA3,
PTCH1,
SRGN,
RTL10,
PSMD2,
CDK1,
MUL1,
RPS6KA3,
PAEP,
S100A9,
CEBPA,
RAB8A,
COL1A1,
AURKA,
TUG1,
ABCC2,
CCR7,
MEG3,
CD24,
CCR5,
COX1,
MTR,
TRIM63,
SLC2A4,
SLAMF1,
SKP2,
PMEL,
NGF,
ASCC2,
SPHK2,
CD27,
CHEK1,
OAS3,
ODC1,
ITGB7,
RELN,
AREG,
HLA-G,
FOS,
SIRT1,
HMOX1,
CCN1,
FLT1,
IGHV3-52,
FOXM1,
TCL1A,
IL1A,
ATM,
HLA-DRB1,
CYP2C8,
CFDP1,
MIR192,
HDAC4,
TPX2,
NAMPT,
HNF4A,
CXCR3,
AGO2,
USP14,
HP,
CRTC1,
PKD2L1,
TNFRSF10A,
DAZAP2,
ALDH1A1,
MIR125A,
FOXP1,
GJA1,
SND1,
XIAP,
HLA-E,
CIB1,
XRCC4,
RASSF1,
E2F1,
ADM,
GEMIN4,
GDF15,
PRDX5,
XRCC5,
BCL9,
CTAG2,
CXCL10,
CBLL2,
BDNF,
MIR497,
BGLAP,
EPAS1,
ZDHHC9,
ANGPT1,
ESR1,
EIF4G2,
SPANXA1,
HK2,
USP7,
USP5,
EZH1,
ADAR,
F9,
DPP4,
RRM1,
MELK,
MIB1,
TCL1B,
ALPP,
ALPI,
CCL20,
CX3CL1,
APC,
ADAMTS9,
CCL5,
RUNX2-AS1,
SAT1,
ACKR3,
DICER1,
EEF1E1,
CCL4,
CD33,
ING4,
RET,
ADCYAP1,
CD70,
PTK2,
CD74,
SEMA3A,
DLC1,
CARM1,
ADCYAP1R1,
CASC3,
PAK4,
TAS2R38,
SAMSN1,
PLK2,
PPP1R13L,
CD3EAP,
ABO,
PPARGC1A,
CCR2,
NR0B1,
KLHL1,
AKT2,
RELA,
CIP2A,
LOC105379528,
MAGEC1,
ALCAM,
RAP1A,
BCL2L11,
RAN,
MIR767,
ABCB6,
KDM1A,
RAD51,
DIABLO,
RAD50,
ZNF197,
AHR,
RETN,
SLC22A2,
ADIPOQ,
H3P12,
TAM,
TIMP1,
USP9X,
THPO,
THBS1,
ATF4,
SETD2,
MKNK1,
IL17D,
TNFRSF10D,
PSMG1,
TRBV20OR9-2,
BECN1,
MBTPS1,
HNF1A,
HPGDS,
TNFSF14,
TAZ,
MPC1,
ATR,
IL23A,
BAX,
BIK,
XRCC1,
F11R,
MZB1,
IGK,
ATRAID,
IL22,
IL21R,
TXNRD1,
UCHL5,
SLC40A1,
TSC1,
MAGEC2,
BST2,
MAFK,
CCDC6,
DCDC2,
DLK1,
XAF1,
SFRP2,
VHL,
MYEOV,
CD6,
BIRC5,
IL17RB,
SMPD1,
AURKB,
SETBP1,
NOG,
SLC16A1,
MAP3K7,
SLC7A4,
MAPKAPK2,
KDM3A,
BIRC2,
CD14,
TRIP13,
CD163,
MYDGF,
SYCE1L,
SOCS3,
CCNE1,
SP1,
SYK,
TNFRSF10B,
ANKHD1,
STIM1,
CASP10,
IQGAP1,
STAT1,
MIR1271,
SSX2,
FASLG,
LAMTOR1,
SST,
SQSTM1,
CCNA1,
RUNX1,
NBEA,
HSPB3,
EPHA4,
PTH,
IGHG3,
CSF1R,
HSPB2,
MIR324,
CEACAM6,
GCLC,
MTRR,
SCARNA22,
GLS,
MRE11,
ZFP82,
JUNB,
MIR106B,
MIRLET7E,
JUND,
GRK6,
CRYZ,
MPO,
MIR144,
ISG20,
IPP,
NFE2L2,
RCBTB2,
NPM1,
G6PD,
MIR148A,
MIR146A,
NOTCH2,
GABPA,
IAPP,
GAPDH,
MIR145,
LYST,
SSX2B,
GAS6,
HTC2,
GATA1,
CCR6,
AGFG1,
YBX1,
DUSP2,
PRRT2,
LDHA,
LEP,
HDAC1,
AZIN2,
LGALS3,
LGALS9,
HNRNPA1,
MMP13,
MIR99B,
TPPP2,
DNMT1,
LTA,
HMGB1,
LPL,
LIG3,
POU5F1P4,
EGLN3,
MEFV,
MTDH,
PRIMA1,
GSTM1,
MMP7,
KMT2A,
GADL1,
WNT3A,
TNPO1,
MICB,
CD99,
LOC390714,
HNRNPA1P10,
LAG3,
MGMT,
LAIR1,
KITLG,
IRF8,
ING1,
EDNRA,
PLG,
MIR22,
CYP2C19,
DCC,
CDK5,
NCR3,
FCGR2A,
MAGT1,
FCGR3A,
PDPK1,
FCGR3B,
LBH,
EIF4A2,
CYP1A1,
IFNAR1,
MIR202,
IL27,
PLK1,
EGR1,
EXT1,
EP300,
IGHA1,
EPS8,
MIR29A,
MIR451A,
PRKCB,
PRKCA,
IKBKB,
PRKAB1,
IL1RN,
MIR223,
IL2RA,
PPP1R1A,
CDH2,
IGFBP2,
TRIM56,
POU5F1P3,
CDKN3,
MIR375,
FOSB,
ROR2,
CFL1,
P2RX7,
P4HB,
TNFRSF9,
MIR342,
FOLH1,
ASXL1,
SERPINA5,
MIR18A,
PRDX1,
DDIT3,
MIR186,
FLT3,
FGFR1,
CD52,
CX3CR1,
CRTC2,
MIR363,
RABGEF1,
MCAT,
ST3GAL6-AS1,
DARS-AS1,
MIR340,
KCNRG,
SHISA8,
STAC3,
MCIDAS,
PABPC1P1,
BLOC1S2,
PPP1R16B,
MIR338,
ZNF763,
SPDYA,
IGHV5-78,
LINC01193,
STEAP1,
GPSM1,
AATF,
FOXD3,
HOXC-AS3,
PTENP1-AS,
NUPR1,
PABPC1,
ABCB5,
MYCBP,
MIR335,
RICTOR,
LAMA5-AS1,
BBC3,
MIR331,
NANOS3,
CLEC4D,
MIR425,
TINF2,
LINC00515,
DIMT1,
FBXO9,
PDCD4,
PHF19,
GSTK1,
APEX2,
MMP28,
IBTK,
MRAS,
MIR197,
MLXIP,
MIR193A,
CLSTN1,
LINC02605,
CARD8,
RNA28S5,
MIR182,
RNA28SN4,
MMRN1,
ATF6,
RPIA,
MIR30E,
PRAL,
MIR320A,
MIR150,
MTCO2P12,
TNIK,
SMG1,
MTF2,
MIR30D,
CIC,
VSIG4,
MIR301A,
RPP14,
CIT,
CDC37,
GLMN,
MIR28,
MIR27A,
MIR26B,
MIR23B,
MIR30A,
SLC2A6,
MIR30C1,
PTENP1,
PADI2,
H3P8,
MIR30C2,
CHP1,
H3P13,
MIR215,
KDM6B,
MIR34B,
MAST4,
MAPK8IP2,
PSD4,
LPAR3,
CSAG3,
PADI4,
CSAG2,
MIR93,
LIN28B,
DAPK2,
NUP62,
ANXA2R,
SGK3,
HES5,
PSMA3-AS1,
MAFF,
MIR9-3,
CA13,
RCHY1,
POT1,
SOSTDC1,
SEZ6L,
MIR9-2,
RN7SL263P,
IGHV4-34,
ACSBG1,
MIR130A,
RHOBTB2,
MIR127,
DNMBP,
USP24,
MIR126,
ZNF629,
PPP1R13B,
MIR124-1,
MIR10A,
CERNA3,
SIRT3,
MIRLET7B,
RYBP,
MIR9-1,
SF3B1,
PERCC1,
IRAIN,
CABIN1,
TRAT1,
ZUP1,
FERMT3,
PAG1,
USE1,
PBK,
GPRC5C,
PROK1,
SLC2A9,
RPAIN,
TCHP,
MAGED4,
RNASEH2C,
TCIM,
PMEPA1,
VTRNA2-1,
CHPT1,
SLC12A9,
KREMEN1,
EIF2A,
CIAPIN1,
RASSF4,
CRISPLD2,
PDXP,
DOT1L,
NUP133,
NLRP2,
ORAI1,
MIR1246,
PRINS,
SNORD14B,
LGR4,
RBPMS,
ZNF331,
CAMK2N1,
ATAD1,
HES6,
HAVCR2,
MIR631,
RIOX2,
SOX6,
SUPT20H,
MIR33B,
SPZ1,
SNORD35B,
DEPDC1,
MIR532,
MIR610,
PCBP4,
PLSCR4,
DLL1,
GOPC,
ZKSCAN3,
ASRGL1,
UBE2O,
ZC3H12A,
DHDDS,
TXNDC15,
LIN28A,
DHX40,
TINAGL1,
IFIH1,
FAM72D,
MMP25,
GORASP1,
PDIA2,
OIP5-AS1,
RAPH1,
NEIL1,
WNK1,
SLC2A11,
TRPM8,
MAPKAP1,
CEP70,
ULBP2,
PDCD1LG2,
WDR19,
RALGAPB,
TP73-AS1,
RNA28SN5,
MIR765,
RPTOR,
SESN2,
SEMA6A,
RASSF5,
KIF18A,
POTEF,
HPSE2,
TLR10,
CTDSP1,
RHOU,
MAGED4B,
SLC38A1,
SCPEP1,
ZNF436,
BACH2,
COL18A1,
SNORD14C,
MSTO1,
SNORD14D,
SNORD14E,
MIR193B,
TENT5D,
DERL1,
SLC30A8,
BHLHA15,
CLEC12A,
FEZF1-AS1,
SLC2A12,
MIR520G,
DTX3L,
GOLT1B,
IL23R,
ANGPTL4,
ZNF569,
SLC45A2,
IL34,
LINC00328,
ARMH4,
DCTN4,
MIR509-1,
SLC25A37,
RHOV,
MIR4741,
PDIA3P1,
MPEG1,
LAMTOR2,
MCTS1,
ALKBH3,
UBE2T,
MARCHF8,
MYLIP,
MIR410,
DEL13Q14,
RMC1,
PSC,
MIR4505,
PRSS55,
PADI1,
MIR485,
PIKFYVE,
SLC2A8,
MIR490,
ERO1A,
MIR4449,
SOX8,
RPL17-C18orf32,
A2ML1,
MS4A4A,
EGLN1,
MIR155HG,
NLRP3,
SLC35A4,
TP53RK,
SHC3,
TERF2IP,
CYTOR,
DDX4,
DDIT4,
FOXP2,
ZNF501,
FBLIM1,
PPP1R12C,
TET2,
DPP8,
DCAF15,
CASZ1,
NSD3,
SLC25A21,
ITPRIP,
ADA2,
MIR4254,
FZR1,
LINC01672,
CACUL1,
MIB2,
NRSN1,
SCARA3,
PASD1,
SLCO6A1,
EVL,
CPT1C,
LINC01234,
ETV7,
LINC00461,
SIRT6,
SEZ6,
SNHG18,
NBAS,
SF3B6,
RASD1,
CRNDE,
ZNF44,
IGLL5,
RITA1,
NAT1,
GLIPR1,
IGF2,
IGHM,
IGHG1,
IGHDOR15@,
IGFBP7,
IGFBP4,
IGF2R,
IFNB1,
IL2RB,
IDUA,
ID1,
HSPA8,
HSPA1B,
HSPA1A,
HES1,
JCHAIN,
IL2RG,
ITGAV,
ILF2,
IRF1,
IRAK1,
INPPL1,
INPP5D,
IDO1,
ILK,
IL18,
IL5,
IL13,
IL12RB2,
IL11RA,
IL10RB,
IL10RA,
IL7,
HOXC10,
HOXB7,
HOXA11,
GFER,
GPR42,
CCR10,
SFN,
GOT2,
GLO1,
GLB1,
GDF1,
HOXA1,
GCG,
GBP1,
GARS1,
GAB1,
XRCC6,
IFI6,
GRB2,
GRM3,
GTF2H1,
GZMB,
H2AX,
HAS2,
HCK,
HDAC2,
HFE,
HGFAC,
HIC1,
HLA-DOB,
HLA-DQB1,
HLA-DRB5,
HMBS,
NR4A1,
HOXA@,
ITGAL,
ITGAX,
MMP24,
COX2,
NEDD4,
NDP,
NBN,
NAGLU,
MUC4,
NUDT1,
MSX1,
NOS2,
MRC1,
MPZ,
MPST,
MPG,
MMP15,
MMP8,
NOS1,
NOS3,
ITGB2,
PAFAH1B1,
PDC,
PCYT1A,
PCM1,
PBX3,
PAM,
SERPINE1,
FURIN,
NOTCH3,
PEBP1,
ORC4,
ROR1,
NTF3,
NPPB,
NPC1,
MMP1,
MAP3K10,
MLH1,
STMN1,
CD180,
LTBP3,
LIF,
LGALS8,
LEPR,
LCN2,
LAMP1,
MITF,
LAMA5,
KRT81,
KPNA2,
KLRB1,
KIR3DS1,
ITGB3,
EPCAM,
MARCKS,
SMAD1,
SMAD2,
SMAD3,
SMAD5,
MAGEA1,
MAOA,
MAX,
MBD1,
CD46,
MEIS2,
MAP3K5,
MFAP1,
MGST1,
CIITA,
MIF,
FUT1,
FOLR2,
FOLR1,
CASP2,
CD247,
CD1D,
CCNB1,
CCK,
RUNX3,
CAV1,
CANX,
TNFRSF8,
CALCR,
DDR1,
BUB1B,
BTF3P11,
KLF9,
BRS3,
CD22,
TNFSF8,
FLII,
CHUK,
CNR2,
CCR4,
CMA1,
TPP1,
CLCN5,
CISH,
CHI3L1,
CD48,
CDKN2D,
CDK7,
CDC42,
CDC25C,
CDC20,
CD68,
BRCA2,
BMPR1A,
CEACAM1,
AHCY,
AMY1B,
AMY1A,
AMBP,
ALOX5,
ALK,
CRYBG1,
AGER,
BCL3,
ADRA2B,
ADRA1A,
ADK,
ACVRL1,
ACVR2A,
ACP5,
AMY1C,
ANG,
ANGPT2,
ANXA1,
APOA1,
APOB,
APRT,
ARF1,
ARG1,
RHOH,
ARNT,
ARNTL,
ATF3,
ATP7A,
AXL,
BCHE,
BCL2A1,
COL4A1,
SLC31A2,
MAP3K8,
EPOR,
ETFA,
ERG,
ERCC3,
ERCC2,
ERBB3,
ERBB2,
ENO1,
EDN1,
ENDOG,
EMX2,
ELF4,
ELAVL2,
EIF4EBP1,
EEF1A2,
ETS1,
F2,
F3,
F10,
FASN,
FCAR,
FCER2,
FCGR2B,
FCGRT,
FDPS,
FGA,
FGF1,
FGF13,
FGFR4,
FH,
FHIT,
FLI1,
EDNRB,
LPAR1,
CPOX,
CYP1B1,
DCN,
DAPK1,
CYP3A4,
CYP2D6,
CYP2C9,
CYP2B6,
CYLD,
S1PR1,
CTSK,
CCN2,
CSNK1A1,
HAPLN1,
CREBBP,
CREB1,
ACE,
DDB1,
DDX5,
TIMM8A,
DHCR24,
DHFR,
DIO3,
DKC1,
DLD,
DMD,
DNASE1,
DNMT3A,
SLC26A3,
TSC22D3,
DUSP5,
DUSP8,
TYMP,
ENPP1,
ENPP2,
PDZK1,
TNKS,
TNFRSF10C,
TNFRSF18,
TNFRSF6B,
ADAM23,
TNFSF9,
RIPK1,
DYNLL1,
PROM1,
NCOA1,
USO1,
KMO,
IKBKG,
ITGA8,
ENC1,
SOCS2,
DLEU2,
UCN,
CDY1,
LPAR2,
PDCD5,
CBFA2T2,
SLC16A3,
SLC16A4,
FCGR2C,
PRC1,
NR1I2,
SEMA5A,
MAP3K14,
BTRC,
MBD2,
SPHK1,
ARHGEF7,
OFD1,
SMARCA5,
CUL4A,
VWF,
ZAP70,
YWHAE,
YY1,
WT1,
WNT5A,
WEE1,
VRK1,
DYRK2,
TRPV1,
BEST1,
VIM,
VDAC1,
USP1,
NR1H2,
ZNF70,
TRIM25,
ZMYM2,
LAPTM5,
EVI5,
DEK,
BAG6,
RNF217-AS1,
TFPI2,
FGF23,
CLLS2,
NCOA3,
USP9Y,
ARID1A,
TRRAP,
BCAR3,
RECK,
SLC16A7,
MTA2,
PTTG1,
CDK2AP2,
CRTAP,
TACC3,
PRMT5,
ST3GAL6,
RACK1,
STUB1,
TRIB1,
AKT3,
PSMD14,
PSME3,
PDZK1IP1,
ARPC5,
EDIL3,
ABCC5,
SEMA4D,
PRDX4,
ARPC1A,
CXCL13,
GNLY,
COLEC10,
KHDRBS1,
CXCR6,
NRG3,
OGA,
NES,
KDM5B,
ZMYND11,
CCL27,
LILRB1,
SLC26A1,
MALT1,
BCL2L10,
SCO2,
PDLIM7,
NCR2,
CHD1L,
VPS4B,
TBPL1,
NAPSA,
HOMER1,
NCR1,
COX5A,
USP15,
KL,
LONP1,
KLF4,
ASIC3,
CD83,
ITGB1BP1,
MINPP1,
SOX13,
APOBEC3B,
RBM39,
CYTIP,
CARTPT,
NCOR2,
TTI1,
HERPUD1,
DCAF1,
RAPGEF5,
MTSS1,
SPATA2,
GAB2,
TELO2,
UBAP2L,
DLEC1,
UGCG,
UCHL1,
PFKFB3,
RBBP8,
RNASE2,
RGS1,
RENBP,
REG1A,
RECQL,
OPN1LW,
RBBP5,
RNF6,
RARA,
RANBP2,
RAG2,
MOK,
RAD23B,
PTN,
RNASE3,
RNH1,
UBE2G1,
ATXN1,
SELL,
SELE,
CXCL11,
CCL8,
CCL7,
SCN7A,
RYR1,
SNORD15A,
RRM2,
RPS27A,
RPS27,
RPL17,
RPL5,
RPA1,
PTBP1,
PSME2,
PSMD10,
PLAUR,
PPP3CA,
PON1,
POLD1,
PMP22,
PML,
PLXNB1,
PLAT,
PSMD4,
PKM,
PIK3R2,
PIK3R1,
PIGA,
ABCB4,
PFN1,
PRB1,
PRKAA1,
PRKAA2,
MAPK7,
MAPK9,
MAP2K1,
PSAP,
PSMA3,
PSMA6,
PSMB1,
PSMB4,
PSMB5,
PSMB8,
PSMB9,
PSMB10,
PSMC1,
PSMC6,
SELP,
SEMG1,
SELENOW,
TERF1,
KLF10,
THBS2,
THBD,
TGFA,
TFPI,
NAT2,
TERC,
ADAM17,
TEAD1,
TDG,
TCF19,
GCFC2,
SERPINA7,
TAPBP,
TIMP3,
TJP1,
TLR3,
TSPAN7,
TMSB4X,
TNFAIP3,
TNFRSF1B,
TOP1,
TPO,
CRISP2,
TRAF2,
TRPC1,
TSC2,
TSHR,
TTK,
TYRO3,
UBA1,
TAP2,
SYT1,
SFRP1,
SKIV2L,
SNCA,
SIGLEC1,
SMO,
SMARCB1,
SLC3A2,
SKP1,
SKI,
SYCP1,
SIM2,
SH3GL3,
SH3GL1,
SGK1,
SRSF2,
SFRP5,
FSCN1,
SOD1,
SORL1,
SOX1,
SOX2,
SOX4,
SOX11,
SRI,
ITPRID2,
SSTR4,
SSX1,
SSX4,
STAT5A,
STAT5B,
STK11,
STX4,
SULT1A1,
TERF2
Drugs
(3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-0ne,
17-allylamino-17-demethoxygeldanamycin,
18-(p-(
(3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-0ne,
17-allylamino-17-demethoxygeldanamycin,
18-(p-(,
6-[4-Deoxy-4-[(2E,4E)-tetradecadienoylglycyl]amino-L-glycero-B-L-manno-heptopyranosyl]amino-9H-purine,
Acadesine,
Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus,
Aplidine,
Arsenic trioxide
(
Arsenic Trioxide Accord,
Arsenic trioxide Mylan,
Arsenic trioxide medac,
TRISENOX
),
Autologous T lymphocyte-enriched population of cells transduced with a lentiviral vector encoding a chimeric antigen receptor targeting human B cell maturation antigen with 4-1BB and CD3-zeta intracellular signalling domains,
Autologous T-cells transduced with lentiviral vector encoding an anti-SLAMF7 CD28/CD3-zeta chimeric antigen receptor,
Autologous ex-vivo-expanded peripheral polyclonal lymphocytes enriched in activated natural killer cells (CellProtect),
Autologous human T cells genetically modified ex-vivo with a lentiviral vector encoding a chimeric antigen receptor for B-cell maturation antigen,
Belantamab mafodotin
(
Blenrep
),
Bortezomib
(
BORTEZOMIB ACCORD,
BORTEZOMIB FRESENIUS KABI,
BORTEZOMIB HOSPIRA,
BORTEZOMIB SUN,
VELCADE
),
Carfilzomib
(
KYPROLIS
),
Chimeric monoclonal antibody against kappa myeloma antigen,
Daratumumab
(
DARZALEX
),
Deoxyribose phosphorothioate (5´-tct-ccc-agc-gtg-cgc-cat-3´),
Dexamethasone (40 mg tablet)
(
NEOFORDEX
),
Doxorubicin hydrochloride (liposomal)
(
DOXIL
),
Elotuzumab
(
EMPLICITI
),
Filanesib,
Human anti-intercellular adhesion molecule-1 monoclonal antibody,
Human monoclonal antibody against HLA-DR,
Humanised anti-HM1.24 monoclonal antibody,
Humanised monoclonal antibody against CD38
(
SARCLISA
),
Imexon,
Ixazomib
(
NINLARO
),
Lenalidomide
(
LENALIDOMIDE ACCORD,
REVLIMID
),
Marizomib,
Maytansinoid-conjugated humanized monoclonal antibody against CD56,
Melphalan
(
EVOMELA,
ALKERAN
),
Milatuzumab,
N-(methyl-diazacyclohexyl-methylbenzamide)-azaphenyl-aminothiopyrrole,
N2'-Deacetyl-N2'-[4-methyl-4-(oxobuthyldithio)-1-oxopentyl]-maytansine-chimerized anti- CD138 IgG4 monoclonal antibody,
Oprozomib,
Panobinostat
(
FARYDAK
),
Perifosine,
Plitidepsin,
Pomalidomide
(
IMNOVID (previously POMALIDOMIDE CELGENE),
POMALYST
),
Recombinant histidine-tagged idiotype immunoglobulin Fab fragment of clonal B-cell receptors,
Recombinant human monoclonal IgM antibody targeting glucose-regulated protein 78,
Reduced oxidised N-acetyl heparin,
Selinexor
(
XPOVIO
),
Siltuximab
(
SYLVANT
),
Synthetic signal peptide of human Mucin-1 (amino acids 1-21),
Thalidomide
(
THALIDOMIDE CELGENE,
THALOMID
),
Venetoclax
(
VENCLEXTA,
VENCLYXTO
),
Vorinostat
(
ZOLINZA
),
Wilms' tumour 1 (WT1) vaccine,
haematopoietic stem cells and blood progenitors umbilical cord-derived expanded with (1R, 4R)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine dihydrobromide dihydrate,
melphalan flufenamide
Registered!
Multiple myeloma is a form of cancer that occurs due to abnormal and uncontrolled growth of plasma cells in the bone marrow. Some people with multiple myeloma, especially those with early stages of the condition, have no concerning signs or symptoms. When present, the most common symptom is anemia, which can be associated with fatigue and shortness of breath. Other features of the condition may include multiple infections; abnormal bleeding; bone pain; weak and/or easily broken bones; and numbness and/or weakness of the arms and legs. The exact underlying cause of multiple myeloma is currently unknown. Factors that are associated with an increased risk of developing multiple myeloma include increasing age, male sex, African American race, radiation exposure, a family history of the condition, obesity, and/or a personal history of monoclonal gammopathy of undetermined significance (MGUS). Treatment varies based on many factors, but may include one or more of the following interventions: chemotherapy, corticosteroid medications, targeted therapy, stem cell transplant, biological therapy, radiation therapy, surgery and/or watchful waiting.