Takayasu Arteritis

Watchlist

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Retrieved

2022-04-26

Source

Gard

Trials

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Genes

HLA-B, IL12B, MLX, NOS2, IL6, RPS9, EHMT2, MSH5, HLA-DOB, PCSK5, TNF, TNXB, PRRC2A, EHMT2-AS1, FRMD4A, CYP21A2, ATF6B, ZNRD1ASP, KLHL33, DDR1, PSORS1C1, SAPCD1, MSH5-SAPCD1, PTK2B, HLA-DRB1, CRP, SMUG1, GCA, PTX3, RBM45, ACR, FCGR2A, HLA-DQA1, IL6R, HLA-A, FCGR3A, IL10, HLA-DPB1, MICA, IL23A, FGF2, LILRB3, VCAM1, VEGFA, FGF13, S100A8, PTPN22, MTOR, HSPD1, NOD2, FSTL3, F5, ANP32B, HMGB1, SPATA2, HDAC9, TMSB10, TNFSF9, TNFSF13, TPI1, TNFRSF1B, TLR4, ESR1, SGTB, NAAA, ANGPT1, AGER, RPL17-C18orf32, LINC01672, WG, AIC, ALB, IL23R, LYPD4, RIPPLY2, CD59, ADA2, IL17F, ABCC11, TUBA1C, CHI3L1, COL18A1, EEFSEC, SEMA6A, EGR1, TRG, TIMP1, STAT3, TRD, TRBV20OR9-2, MICB, MEF2A, LEP, LAMP2, JAK2, ITGB3, ITGA2B, CXCL10, IL17A, IL12RB2, IL12RB1, IL12A, CXCL8, IL4, IL2, IL1RN, IL1B, IL1A, IFNG, IFNA13, IFNA1, MMP2, MMP3, MMP9, MOK, FN1, ABCC8, HSPA4, SNCA, SELP, CCL5, CCL2, S100A12, RPL17, CXCL1, MPO, PON1, PF4, PDCD1, ADA, HLA-DOA, NFKBIL1, MYD88, MTHFR, HLA-DPA1, SERPINE1

Drugs

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Takayasu arteritis is a condition that causes inflammation of the main blood vessel that carries blood from the heart to the rest of the body (aorta) and its associated branched blood vessels. As a result of the inflammation, the blood vessel walls become thick and make it difficult for blood to flow. Over time, impaired blood flow causes damage to the heart and various other organs of the body. Although the cause remains unknown, Takayasu arteritis appears to be an autoimmune condition, in which cells that fight infection and disease are wrongly targeted against the body's own tissues.