Retinitis Pigmentosa, Y-Linked

Watchlist
Retrieved
2019-09-22
Source
Trials
Genes
Drugs

Clinical Features

Zhao et al. (1995) reported a 4-generation Chinese family in which retinitis pigmentosa affected only males. All sons of affected males were affected, but all 4 daughters of affected males (and all children of these daughters) were healthy.

Inheritance

According to Zhao et al. (1995) the probability of autosomal dominant inheritance in the family they reported is only 1:8,192. Therefore, the authors proposed Y-linked inheritance as a possible explanation for the pattern in this family.