Idiopathic Thrombocytopenic Purpura
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
FCGR2C,
ADAMTS13,
CTLA4,
MS4A1,
FOXP3,
CD19,
ICOS,
TNFRSF13B,
STAT3,
FAS,
STAT1,
TNFRSF13C,
KRAS,
TPP2,
KMT2D,
GALC,
RFXANK,
ZAP70,
KDM6A,
FCGR2A,
TNFSF12,
ARHGEF1,
RASGRP1,
RFX5,
THPO,
TPO,
IL4,
CIITA,
MPL,
IL10
FCGR2C,
ADAMTS13,
CTLA4,
MS4A1,
FOXP3,
CD19,
ICOS,
TNFRSF13B,
STAT3,
FAS,
STAT1,
TNFRSF13C,
KRAS,
TPP2,
KMT2D,
GALC,
RFXANK,
ZAP70,
KDM6A,
FCGR2A,
TNFSF12,
ARHGEF1,
RASGRP1,
RFX5,
THPO,
TPO,
IL4,
CIITA,
MPL,
IL10,
NFKB1,
IL7R,
NFKB2,
PNP,
TNF,
NRAS,
PRKCD,
IFNG,
ACP5,
RFXAP,
SMPD1,
CR2,
FCGR3A,
ITGA2B,
ADA,
CASP10,
CD81,
FASLG,
IL2,
TNFSF13B,
IL18,
IL17A,
IL1B,
IL22,
IL21,
DNMT3B,
IL6,
FCGR2B,
TGFB1,
HLA-DRB1,
ITGB3,
HAVCR2,
LTA,
IL17D,
ISG20,
ABCB1,
GP1BA,
CD86,
IL17F,
IL1RN,
CD40,
FCGRT,
KRT20,
IL27,
IL2RA,
IL11,
CXCL12,
SELP,
RBM45,
HT,
NCAM1,
PRB2,
HPSE,
HLA-A,
CD40LG,
NR3C1,
GP9,
MSC,
FCGR1A,
GP6,
SYK,
FCGR1B,
IL18BP,
GATA3,
CD72,
CD274,
CSF2,
CXCR4,
PTPN22,
ACSBG1,
IL37,
LEP,
KIR2DS2,
KIR3DL2,
KIR3DL1,
CXCL13,
KIR2DL2,
MIR146A,
NOTCH1,
MBD4,
IL23R,
IGHV3-69-1,
IGHJ4,
TNFSF13,
NLRP3,
PDCD1,
VWF,
IL33,
PTEN,
RAPH1,
CCL2,
IL23A,
MYDGF,
ABO,
TNFRSF17,
FCGR3B,
CD44,
IL1A,
CD47,
APOH,
CXCR3,
GATA2,
CD69,
CDKN2B,
HES1,
HOXD13,
GZMB,
GEM,
CNR2,
CRP,
CD34,
HLA-DOA,
DNMT3A,
CXCL10,
CD38,
RUNX3,
TRDV3,
TRDV2,
RUNX1,
CLEC1B,
TRDV1,
CD28,
TBX21,
NXT1,
PYCARD,
ENTPD1,
MBL3P,
DLL1,
JAK2,
IGHV3OR16-7,
IGHJ6,
CCR6,
OPTN,
TSHZ1,
TCIRG1,
IKZF1,
SEMA4D,
ATG7,
ANP32B,
MRPL28,
CXCR6,
CCR5,
IGHV4-28,
MALT1,
SUB1,
CCR3,
CUL9,
TBC1D9,
CD70,
HAVCR1,
CD68,
CASP3,
RTEL1,
MEG3,
CAMP,
TRIT1,
MIR212,
MIR221,
MIR33A,
MIR99A,
MIR382,
MIR409,
ADAM10,
MIR92B,
CARMN,
CCR2,
MIR765,
ACTN1,
MIR1185-2,
MIR3162,
MIR3125,
MICA,
COMMD3-BMI1,
IFNG-AS1,
LOC102723407,
GATD3B,
LOC102724971,
UPK3B,
MTCO2P12,
MIR200C,
MIR195,
MIR183,
BCL2,
SCAMP2,
BMI1,
CXCL16,
CXCR5,
HPSE2,
CARD9,
BID,
GGCT,
TRPM8,
BCL6,
CDCA5,
ADRB3,
STS,
AR,
DNMT3AP1,
ANXA1,
AHCY,
JAG1,
MIR106B,
MIR125A,
MIR130A,
MIR142,
CX3CR1,
F2RL3,
SCAMP1,
MAPK1,
NELL1,
CXCL8,
IL5,
IL4R,
NOTCH2,
IL2RB,
IL1R1,
SERPINE1,
IKBKB,
IGH,
MAPK8,
SELE,
IFNB1,
PTGS1,
PTGS2,
PTPRC,
RHD,
ROS1,
S100A8,
HOXB4,
CCL11,
CCL18,
IL9,
NAP1L1,
MYH9,
COX2,
KIR2DL3,
KIR2DS1,
KIR2DS3,
KIR2DS5,
IRF4,
INSRR,
KLRD1,
IDO1,
LGALS9,
IL16,
SMAD7,
MAP6,
MBL2,
MDM2,
IL12A,
MIF,
MMP9,
MNAT1,
IL10RA,
MRC1,
COX1,
HOXA5,
HLA-DRB3,
CD83,
FCN2,
GATA4,
RNF112,
FKBP5,
EOS,
ARHGEF5,
FGF2,
CDR3,
GATD3A,
GFI1B,
IKBKG,
FCER1G,
SIAH2,
NRP1,
CDK5R1,
VNN1,
TIMELESS,
BCL10,
EPHB2,
MBD2,
ITGA2,
DECR1,
DDX5,
VEGFA,
VDR,
GCHFR,
TNFRSF4,
SLC7A4,
HLA-DPB1,
TRIM21,
RO60,
HLA-B,
STAT4,
HIF1A,
TBXT,
TRBV20OR9-2,
TRGV1,
TRGV2,
TG,
THBD,
GRN,
TIMP3,
TLR4,
TNFAIP3,
TP53,
GP5,
TRAF6,
TNFSF4,
H3P9
Drugs
A highly purified formulation of Staphylococcus aureus protein A,
Anti RhO (D) immune globulin intravenous (human)
(
WINRHO SD
),
Avatrombopag maleate
(
DOPTELET
)
A highly purified formulation of Staphylococcus aureus protein A,
Anti RhO (D) immune globulin intravenous (human)
(
WINRHO SD
),
Avatrombopag maleate
(
DOPTELET
),
Efgartigimod alfa,
Eltrombopag olamine
(
PROMACTA,
REVOLADE
),
Fostamatinib disodium
(
TAVALISSE
),
Human normal immunoglobulin
(
GAMMAGARD,
GAMMAGARD LIQUID,
GAMMAPLEX,
ENDOBULINE,
FLEBOGAMMA DIF,
HIZENTRA,
HYQVIA,
KIOVIG,
OCTAGAM,
INTRAGLOBIN F,
PRIVIGEN,
SANDOGLOBULINE,
TEGELINE
),
Recombinant human soluble Fc-gamma receptor II b,
Rilzabrutinib,
Romiplostim
(
NPLATE
),
Rozanolixizumab,
sutimlimab
Registered!
Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission.