Buerger Disease
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
VCAM1,
AGER,
UCN,
CRHR1,
TSHR,
IL1B,
IL6,
CD34,
IGF1,
ICAM1,
TNF,
IFNG,
IGF1R,
IL1A,
MTCO2P12,
HLA-DRB1,
IL13,
CXCL8,
IL10,
HLA-DPB1,
IL17A,
VEGFA,
COX2,
NOS3,
HLA-DQA1,
PTGS2,
FGF1,
F2,
RBM45,
MIR21
VCAM1,
AGER,
UCN,
CRHR1,
TSHR,
IL1B,
IL6,
CD34,
IGF1,
ICAM1,
TNF,
IFNG,
IGF1R,
IL1A,
MTCO2P12,
HLA-DRB1,
IL13,
CXCL8,
IL10,
HLA-DPB1,
IL17A,
VEGFA,
COX2,
NOS3,
HLA-DQA1,
PTGS2,
FGF1,
F2,
RBM45,
MIR21,
CD44,
HAVCR2,
EDN1,
MIR146A,
STAT1,
SPAM1,
CCL5,
SELE,
MICA,
ST8SIA1,
TLR4,
TMX2-CTNND1,
THY1,
SRP9,
STAT3,
SRP54,
GATD3B,
TGFB2,
UCP1,
TGFB1,
TG,
SYK,
PDCD4,
GATD3A,
LINC01193,
BCAR1,
RNU1-1,
SS18L1,
UBE2C,
HPSE,
IL21R,
SLC38A2,
SEMA5B,
ZNF263,
PTX3,
IL23R,
SMC3,
CASS4,
IL17RC,
ST3GAL5,
PRRT2,
SAT2,
NLRP3,
FOXP1,
SLIT2,
ACTA2,
PTPRC,
CTNND1,
HLA-B,
HLA-A,
HGF,
CXCL1,
NR3C1,
GATA3,
NR5A1,
FLT1,
PTK2B,
FABP4,
CSF1,
HMGB1,
CSE1L,
CD40LG,
CD40,
CD14,
BMP4,
OPN1SW,
BCL2,
APOA1,
AKT1,
JAG1,
HLA-DOA,
HOXB2,
PSMD1,
NOTCH1,
MAPK8,
PRKCB,
PRKCA,
PPARG,
PIK3CG,
PIK3CD,
PIK3CB,
PIK3CA,
SERPINE1,
ADAM10,
MYD88,
HOXB3,
MMP3,
MKI67,
SMAD2,
LOX,
LGALS9,
KNG1,
CXCL10,
IL16,
IL1RN,
HES1,
OMG
Registered!
Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.