High-Arched Palate
Watchlist
Retrieved
2021-01-18
Source
Trials
—
Genes
SATB2,
TCOF1,
FGFR1,
SHOX,
STAT3,
SPECC1L,
OBSL1,
SMCHD1,
TAB2,
SIK3,
GRIP1,
AGTPBP1,
DDHD2,
EXOC6B,
AP4E1,
PLXND1,
POGZ,
ABL1,
HYOU1,
CEP152,
RAB18,
RAB3GAP1,
DHX30,
FASTKD2,
MRAS,
ERLIN2,
AP4S1,
TLK2,
CLP1,
WDR4
SATB2,
TCOF1,
FGFR1,
SHOX,
STAT3,
SPECC1L,
OBSL1,
SMCHD1,
TAB2,
SIK3,
GRIP1,
AGTPBP1,
DDHD2,
EXOC6B,
AP4E1,
PLXND1,
POGZ,
ABL1,
HYOU1,
CEP152,
RAB18,
RAB3GAP1,
DHX30,
FASTKD2,
MRAS,
ERLIN2,
AP4S1,
TLK2,
CLP1,
WDR4,
AP4B1,
CNOT1,
TGDS,
KAT6B,
GMPPB,
TMEM216,
TACO1,
IER3IP1,
ZDHHC9,
POLR1D,
YARS2,
NSDHL,
GEMIN4,
RRM2B,
EFEMP2,
PSAT1,
LRP12,
DSE,
BLNK,
CLCF1,
ANKRD11,
UBE2T,
SETD2,
PGAP2,
SLC17A5,
FBXL3,
TCTN3,
SETBP1,
SIN3A,
NIPBL,
RAB3GAP2,
PIGN,
ATP6V0A2,
EBP,
SEC23B,
SEC23A,
ACTL6B,
CHST3,
EIF2AK3,
ECEL1,
PEX16,
RECQL4,
COG1,
PLAA,
TRIP4,
TRIP12,
CRLF1,
HACD1,
ARHGEF2,
AP4M1,
SMC3,
SEMA5A,
HERC1,
AP1S2,
DPM2,
PEX11B,
DNAH11,
DCHS1,
CASK,
CNTNAP1,
PEX3,
OFD1,
CUL4B,
GNPAT,
PIGL,
TBX4,
POLR1C,
FARSB,
COG5,
MAD2L2,
TUBB3,
KLHL41,
APC2,
SPEG,
ZMPSTE24,
IRX5,
CD96,
ALG3,
PQBP1,
HUWE1,
MAMLD1,
PUM1,
GNE,
SLC12A6,
MED12,
SEC24D,
RUSC2,
KIAA0753,
ZBTB24,
EIF4A3,
TMEM94,
FRMPD4,
KMT2B,
IFT140,
KCNK9,
PIGT,
COLQ,
NEK9,
GSC,
A2ML1,
TBC1D20,
SYT2,
B3GALT6,
EARS2,
SP7,
COX20,
TOE1,
CHST14,
TBCK,
PGAP3,
G6PC3,
SLC39A13,
OTUD6B,
SCARF2,
ALG2,
SHANK3,
PIGY,
COX14,
WDR73,
ZNF341,
ATAD1,
PIGO,
MYO18B,
MYPN,
MEGF10,
SLX4,
KCTD7,
ESCO2,
SPRED1,
LGI4,
KLLN,
PET100,
KBTBD13,
MYMK,
AGRN,
KIF7,
CTU2,
FREM2,
FAM149B1,
SH3PXD2B,
DOK7,
UNC80,
PIGW,
KANSL1,
CHAMP1,
NALCN,
STAC3,
RNASEH1,
BRAT1,
AK9,
TUBB,
FLCN,
IBA57,
ALG14,
ASXL1,
ARX,
SPATA5,
COA8,
UTP23,
KIAA1109,
CCDC47,
LRRC8A,
LMOD3,
KLHL7,
ZC4H2,
HDAC8,
LMBRD1,
IFT122,
TRMU,
PEX26,
PIGV,
OSGEP,
ASXL2,
FANCI,
SETD5,
RFWD3,
MSTO1,
FANCL,
PHIP,
NSUN2,
MAGEL2,
PUS7,
TMCO1,
PRMT7,
RIN2,
ADAM22,
MAP3K20,
RAB23,
FAM20C,
HYMAI,
SLC10A7,
NUP107,
BRIP1,
SLC2A10,
ASXL3,
PUS1,
FRAS1,
PYROXD1,
PALB2,
FAT4,
EFL1,
CCDC28B,
CPLANE1,
UPF3B,
NSD1,
SMOC1,
PIEZO2,
SLC5A7,
MPP4,
SPTBN4,
EPG5,
FANCM,
WDR35,
ARID1B,
TBC1D24,
GATAD2B,
SNX14,
SELENON,
THOC2,
CDC45,
LAGE3,
ARID1A,
HNRNPU,
HNRNPH2,
HBA2,
HBA1,
GNB1,
GLE1,
GFPT1,
GBA,
GATA4,
FUT8,
FLNB,
FLNA,
FH,
FGFR2,
FGF8,
FBN2,
FBN1,
FANCG,
FANCF,
FANCB,
BPTF,
FANCE,
FANCD2,
FANCC,
FANCA,
EYA1,
ERCC4,
EP300,
HNRNPK,
HPGD,
ACTA1,
HRAS,
TRNN,
TRNE,
MTM1,
ALDH6A1,
KMT2A,
MID1,
MECP2,
SMAD3,
LRP4,
LMNA,
LIG4,
LAMB2,
KRAS,
KCNQ1,
KCNJ6,
KCNJ2,
KCNH1,
ANOS1,
ITGA7,
INSR,
IGLL1,
IGHM,
IGF1R,
IGBP1,
HSPG2,
HSPA9,
HSD17B4,
MEGF8,
EFNB1,
ECM1,
DVL3,
CDH11,
CD79B,
CD79A,
CBS,
CACNA1C,
TMEM258,
MYRF,
BRCA2,
BRAF,
BRCA1,
FOXL2,
BMP4,
BMP2,
BBS1,
ATRX,
ATR,
ATP7A,
ATP6V1E1,
ATP6V1B2,
ATP6V1A,
ARCN1,
ABCC6,
APC,
ANK1,
BIN1,
AKT1,
AEBP1,
CFL2,
CHAT,
CHRNA1,
COX10,
DVL1,
DPAGT1,
DOCK3,
DHPS,
DDX11,
DBH,
CTNND2,
CTNNB1,
CTBP1,
CSNK2A1,
CREBBP,
CPT2,
COX8A,
CHRNB1,
COX6B1,
COL13A1,
COL12A1,
COL11A1,
COL6A3,
COL6A2,
COL6A1,
CNTN1,
CLTC,
CHRNG,
CHRNE,
CHRND,
TRNS1,
MUSK,
MYCN,
TFAP2A,
TBX1,
MAP3K7,
TAF6,
TAF1,
VAMP1,
SRY,
SOS2,
SOS1,
SON,
SNRPB,
SNAP25,
SMS,
SMARCB1,
SLC25A1,
SLC18A3,
SKI,
SIX1,
SIM1,
SET,
SDHD,
SDHC,
SDHB,
SCO1,
SCN4A,
SC5D,
RYR1,
RRAS,
TCF3,
TGFB3,
RPS19,
TGFBR1,
NAA10,
SMC1A,
KDM5C,
RBM10,
USP9X,
LZTR1,
MKKS,
KMT2D,
PDHX,
MOGS,
PCGF2,
YWHAE,
XRCC2,
WNT7A,
WNT5A,
KDM6A,
USH2A,
SLC35A2,
TWIST1,
TTN,
TRPS1,
TRIO,
TPM3,
TPM2,
TNNT3,
TNNI2,
TGFBR2,
RPS23,
RPS6KA3,
MYH2,
PIGH,
PGM3,
PEX14,
PEX13,
PEX12,
PEX10,
PEX6,
PEX1,
ENPP1,
PDE6D,
PAX1,
PAK3,
PAH,
PAFAH1B1,
ORC1,
NUP88,
DDR2,
NRAS,
NOTCH3,
NOTCH2,
NFIX,
NEK1,
NEB,
MYO9A,
MYL2,
MYL1,
MYH7,
MYH3,
PIGA,
PIK3CA,
RIT1,
PIK3R1,
REV3L,
RET,
RASA2,
RAPSN,
RAP1B,
RAP1A,
RAF1,
RAD51C,
RAD51,
RAD21,
PEX5,
PEX2,
PEX19,
PURA,
PTPN14,
PTPN11,
PTEN,
PSEN1,
MAP2K2,
MAP2K1,
PPP2CA,
PPP1CB,
EXOSC9,
PMM2,
PLOD1,
PLAGL1,
OCLN,
PANK2
Drugs
—
Registered!
Congenital anomaly
A high-arched palate (also termed high-vaulted palate) is where the palate is unusually high and narrow. It is usually a congenital developmental feature that results from the failure of the palatal shelves to fuse correctly in development, the same phenomenon that leads to cleft palate. It may occur in isolation or in association with a number of conditions. It may also be an acquired condition caused by chronic thumb-sucking. A high-arched palate may result in a narrowed airway and sleep disordered breathing.
Examples of conditions which may be associated with a high-arched palate include:
- Allergic rhinitis
- Apert syndrome
- Crouzon syndrome
- Down syndrome
- Ehlers-Danlos Syndrome
- Fragile X syndrome
- Incontinentia pigmenti
- Marfan syndrome
- Treacher Collins syndrome
- Upper Airway Resistance Syndrome
See also
- Minor physical anomalies
- Bardet–Biedl syndrome