Penile Agenesis
Watchlist
Retrieved
2021-01-23
Source
Trials
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Genes
NR5A1,
SRD5A2,
AR,
KISS1R,
FGF8,
FGFR1,
SOX2,
CYP17A1,
GNRHR,
MAMLD1,
CHD7,
PWAR1,
PROKR2,
SETBP1,
NPAP1,
SMCHD1,
PIGP,
RLIM,
SLC25A24,
ZFPM2,
KAT6B,
ORC6,
FLRT3,
INTU,
RAB3GAP2,
POMT2,
SAMHD1,
KIAA0556,
GMPPB,
C2CD3
NR5A1,
SRD5A2,
AR,
KISS1R,
FGF8,
FGFR1,
SOX2,
CYP17A1,
GNRHR,
MAMLD1,
CHD7,
PWAR1,
PROKR2,
SETBP1,
NPAP1,
SMCHD1,
PIGP,
RLIM,
SLC25A24,
ZFPM2,
KAT6B,
ORC6,
FLRT3,
INTU,
RAB3GAP2,
POMT2,
SAMHD1,
KIAA0556,
GMPPB,
C2CD3,
NSMF,
SIN3A,
PNKP,
RAB18,
CILK1,
SGPL1,
HERC2,
PIGQ,
LARGE1,
HS6ST1,
SEMA3E,
KIAA0586,
FIG4,
SRA1,
HUWE1,
MKRN3-AS1,
KLHL41,
SEMA3A,
COG5,
RNASEH2A,
COLEC10,
POMT1,
PNPLA6,
B4GAT1,
TREX1,
WWOX,
PHF21A,
ACTA1,
NDUFB11,
MAGEL2,
FAT4,
SLC25A22,
EHMT1,
DHDDS,
DCAF17,
FRAS1,
KLHL15,
B9D2,
TRIM8,
SPRY4,
LAS1L,
RNASEH2C,
KIAA1109,
PHF6,
ALKBH8,
CEP41,
TOE1,
TBC1D20,
KLHL40,
SIK1,
ARX,
RNASEH2B,
TAPT1,
FKRP,
INPP5E,
IL17RD,
SLC29A3,
FGF17,
VAC14,
POLR3B,
WDR11,
MCTP2,
HDAC8,
LMOD3,
THOC2,
CCDC28B,
CCDC141,
DMRT3,
ALX4,
PROK2,
EBF3,
PIEZO2,
FAM111A,
IFIH1,
ALG12,
ACTB,
CUL4B,
HESX1,
DVL3,
EIF2S3,
ERCC2,
ERCC6,
EXT2,
SNORD116-1,
FZD2,
GATA4,
PWRN1,
GLI2,
GLI3,
GNAO1,
GNRH1,
GRIA3,
HCCS,
HOXA13,
HSD3B2,
FEZF1,
CTU2,
IPW,
STT3A,
ANOS1,
ECE1,
DVL1,
TP63,
DUSP6,
ADAR,
NR0B1,
RNU4ATAC,
ARCN1,
ATP6V1A,
ATRX,
AXL,
BBS1,
BUB1B,
MYRF,
CDC6,
CDH11,
CDKN1C,
CHD4,
ERCC8,
COX7B,
CYB5A,
DCC,
DCX,
DHCR7,
DHODH,
KCNA1,
KISS1,
LEP,
LHB,
VAMP7,
TAC3,
TACR3,
TBCE,
TCF4,
TBX3,
UBA1,
UBE2A,
KDM6A,
WNT5A,
WT1,
XRCC4,
MKRN3,
ZBTB16,
RNF113A,
KMT2D,
KDM5C,
CDC45,
STT3B,
OFD1,
CASK,
STXBP1,
CDKL5,
SRY,
SIX6,
LIG4,
RSPO2,
MAP3K1,
MTM1,
NDN,
NEB,
NEUROD2,
ROR2,
OPHN1,
ORC1,
SOX10,
PBX1,
PIGA,
POR,
PTPN11,
SNORD115-1,
RYR1,
SCN2A,
SNRPN,
SOX9,
UBR1,
NR1I2,
SLC52A2,
PAPPA2,
AHRR,
BRD2,
MECP2,
IGF1,
HSD17B3,
GH1,
F2R,
AHR,
SPGF2
Drugs
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Registered!
Penile agenesis is a rare urogenital tract malformation characterized by complete congenital absence of the phallus. It is usually accompanied by a well-developed scrotum and presence of a skin tag at the anal verge (with or without a urethral meatal opening within it). Often, other genitourinary (e.g. cryptorchidism, renal agenesis and dysplasia, urinary reflux, prostate agenesis) as well as non-genitourinary abnormalities (including skeletal and neural disorders, anal stenosis, imperforate anus, cardiac defects) are associated.