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Ankyloblepharon Filiforme Adnatum And Cleft Palate
Omim
Since clefts and ankyloblepharon occur together in the syndrome of cleft lip-palate, paramedian mucous pits of the lower lip, popliteal pterygium, etc. (119500), it is not certain that this represents a separate mutation. ... Evans et al. (1990) reported 3 cases of Edwards syndrome (trisomy 18) with ankyloblepharon filiforme adnatum.
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Palmoplantar Ectodermal Dysplasia
Wikipedia
Types include: Palmoplantar ectodermal dysplasia type 1 or Pachyonychia congenita type I Palmoplantar ectodermal dysplasia type 3 or Acrokeratoelastoidosis Palmoplantar ectodermal dysplasia type 4 or Papillon–Lefèvre syndrome Palmoplantar ectodermal dysplasia type 5 or Tyrosinemia type II Palmoplantar ectodermal dysplasia type 6 or Olmsted syndrome Palmoplantar ectodermal dysplasia type 8 or Meleda disease See also [ edit ] Ectodermal dysplasia References [ edit ] This genetic disorder article is a stub .
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Congenital Estrogen Deficiency
Wikipedia
Congenital estrogen deficiency is a congenital form of hypoestrogenism in which the body is unable to produce or use estrogens . [1] Such conditions include: Aromatase deficiency , a condition in which aromatase is absent and androgens cannot be converted into estrogens . Estrogen insensitivity syndrome , a condition in which the estrogen receptor is defective and unable to respond to estrogens. See also [ edit ] Aromatase excess syndrome Hyperestrogenism References [ edit ] ^ Rochira V, Balestrieri A, Madeo B, et al.
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Peters Anomaly
Gard
Peters anomaly is a feature of the Krause-Kivlin syndrome and the Peters-plus syndrome .
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Congenital Microcoria
Gard
Congenital microcoria that is not associated with an underlying syndrome is caused by a small, missing piece of genetic material (deletion) around a region of chromosome 13 designated as 13q32. ... Congenital microcoria is also a feature of autosomal recessive Pierson syndrome , caused by mutations in the LAMB2 gene.
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Autism
Wikipedia
The disturbance must not be better accounted for by Rett syndrome , intellectual disability or global developmental delay. [6] ICD-10 uses essentially the same definition. [32] Several diagnostic instruments are available. ... Signs of autism may be more challenging for clinicians to detect in females. [105] Autistic females have been shown to engage in masking more frequently than autistic males. [105] Masking may include making oneself perform normative facial expressions and eye contact. [106] A notable percentage of autistic females may be misdiagnosed, diagnosed after a considerable delay, or not diagnosed at all. [105] Conversely, the cost of screening and diagnosis and the challenge of obtaining payment can inhibit or delay diagnosis. [107] It is particularly hard to diagnose autism among the visually impaired , partly because some of its diagnostic criteria depend on vision, and partly because autistic symptoms overlap with those of common blindness syndromes or blindisms . [108] Classification Autism is one of the five pervasive developmental disorders (PDD), which are characterized by widespread abnormalities of social interactions and communication, and severely restricted interests and highly repetitive behavior. [32] These symptoms do not imply sickness, fragility, or emotional disturbance. [35] Of the five PDD forms, Asperger syndrome is closest to autism in signs and likely causes; Rett syndrome and childhood disintegrative disorder share several signs with autism, but may have unrelated causes; PDD not otherwise specified (PDD-NOS; also called atypical autism ) is diagnosed when the criteria are not met for a more specific disorder. [109] Unlike with autism, people with Asperger syndrome have no substantial delay in language development . [110] The terminology of autism can be bewildering, with autism, Asperger syndrome and PDD-NOS often called the autism spectrum disorders (ASD) [9] or sometimes the autistic disorders , [111] whereas autism itself is often called autistic disorder , childhood autism , or infantile autism . In this article, autism refers to the classic autistic disorder; in clinical practice, though, autism , ASD , and PDD are often used interchangeably. [101] ASD, in turn, is a subset of the broader autism phenotype , which describes individuals who may not have ASD but do have autistic-like traits , such as avoiding eye contact. [112] Autism can also be divided into syndromal and non-syndromal autism; the syndromal autism is associated with severe or profound intellectual disability or a congenital syndrome with physical symptoms, such as tuberous sclerosis . [113] Although individuals with Asperger syndrome tend to perform better cognitively than those with autism, the extent of the overlap between Asperger syndrome, HFA, and non-syndromal autism is unclear. [114] Some studies have reported diagnoses of autism in children due to a loss of language or social skills, as opposed to a failure to make progress, typically from 15 to 30 months of age. ... About 10–15% of autism cases have an identifiable Mendelian (single-gene) condition, chromosome abnormality , or other genetic syndrome, [181] and ASD is associated with several genetic disorders. [182] Intellectual disability . ... The grouping of disorders, including PDD-NOS, autism, Asperger syndrome, Rett syndrome, and CDD, has been removed and replaced with the general term of Autism Spectrum Disorders.CHD8, NRXN1, TBR1, SHANK1, PAX6, MECP2, NLGN3, ADNP, UBE3A, NLGN4X, FMR1, MAOA, SHANK3, PTEN, CNTNAP2, IL1RAPL1, TMLHE, CACNA1C, TSC2, KDM5C, SYNGAP1, CHRNA7, PTCHD1, GRIN2B, MACROD2, COMT, ADSL, JMJD1C, IFNG, CSDE1, NTRK2, NSD1, SNRPN, GABRB3, OXTR, MTHFR, BDNF, EN2, SLC25A12, DPYD, SLC6A4, TAF1C, RELN, AVP, FOXP2, DHCR7, BRSK2, MET, RBFOX1, HOXA1, IL6, AVPR1A, GRIK2, DISC1, ITGB3, WNT2, PRKN, NLGN1, GAD1, GLO1, HTR2A, HLA-DRB1, NBEA, NRCAM, NF1, DOCK4, CADPS2, NOS2, ATP10A, AR, ADA, MAPK3, AHI1, CNTN4, ASMT, SHANK2, TPH2, SEMA5A, POMC, LEP, ST8SIA2, ITGA4, PRKCB, MAGEL2, DAB1, GABRA5, NRP2, GABRA4, GABRB1, NRXN3, IMMP2L, LAMB1, DRD3, OXT, SCT, BCL2, TSC1, NRXN2, IL10, SLC9A9, EIF4E, SND1, DLX2, PIK3CG, DRD1, DLGAP2, SERPINE1, IGF1, EGF, HRAS, MEF2C, DIPK2A, TBL1XR1, C4B, RPL10, STK39, PTGS2, AGAP1, MARK1, PRL, STX1A, PON1, EXT1, CACNA1H, GRIA1, GPX1, GRM8, KDM5B, VLDLR, GABBR1, VIP, CADM1, FARP2, GRIN2A, GSTM1, UBE2H, RIMS1, SEZ6L2, HLA-A, VWA8, TRRAP, HOXD11, PASK, EGR2, HDLBP, ZMYND11, GJA1, ROBO3, AQP4, ABAT, KCND2, PCDH10, PITX1, MYO1D, SLC19A1, CDH10, PLA2G4A, CDH9, STXBP6, SCAMP5, SLC1A3, LASP1, MAOB, HTR3C, APC, MIF, RORA, DIXDC1, ROBO2, ROBO1, CSMD3, RAB39B, CHRNA4, CHRNB2, CYP19A1, ROBO4, TNFRSF1B, DHFR, NPAS2, ACE, ASIC2, SNTG2, REEP3, HTR3A, DLX1, ADRB2, PDE4A, IL4, IL5, TDO2, GABBR2, CP, PDE4B, PECAM1, PER1, HTR5A, PRF1, NTF4, RNF8, NR4A2, CNTN3, PLAUR, MBD4, HTR1D, PRLR, MTF1, HTR1B, HTN1, IGF2, IGFBP3, TF, IL1RN, IL2, IL13, IL15, XDH, XPC, INPP1, KCNMA1, LZTR1, GZMB, GSTP1, SLC6A8, SCN7A, MCC, TCN2, STATH, SLC40A1, KIF1A, GABRA2, GABRA1, COP1, JAKMIP1, GPR155, POU6F2, DAO, BTD, NTF3, ZNF292, KAT8, KMT2E, ASTN2, CALCA, CAT, CHD4, GABRA3, RAB11FIP5, AGO1, ZNF713, GHR, DLL1, ACADSB, MIR23A, MIR106B, ADM, CUL7, WDFY4, PLD5, MBD3, UPB1, FBXO40, AUTS2, PIANP, FOXP1, SCN2A, CTNND2, CDKL5, EHMT1, MED12, ANKRD11, STS, STXBP1, CREBBP, GTF2I, UPF3B, SLC1A2, AKT1, BCKDK, PIK3CA, GABRD, RAI1, RAC1, CHD7, TRIM33, CACNA1A, HNF1B, ATRX, SCN1A, DHDDS, SCN8A, LIMK1, SOX2, PAH, OPHN1, MACROD2-AS1, HDAC8, GABRB2, GABRG2, SATB2, CLIP2, EP300, ELN, SLC9A6, CYFIP2, IQSEC2, PPP3CA, MAN1B1, PPL, PRKAR1A, HESX1, IRAK1BP1, PROKR2, PARD3B, ZNF827, NUS1, RLIM, SYNJ1, CNKSR2, TRAK1, TMEM132B, KCNAB2, RAD21, REV3L, RFC2, DNER, NAV3, FOXN1, TRAF7, DHX30, RREB1, SORCS1, FLCN, POLG, ARNT2, SCN1A-AS1, SLC44A3-AS1, SEMA3E, RPH3AL, PIGL, OTX2, AUTS1, KLLN, PKMP1, LIPG, HDAC4, SLC23A2, SEC23B, SMC3, HCN1, PC, FLG-AS1, LAMA1, PDE4D, SLC13A5, BAZ1B, SDK1, SLC39A11, PKP2, RYR1, RASSF5, SMC1A, PLXND1, SOX3, SOX11, PRR12, FMN2, SIN3A, GTF2IRD1, SH2B1, YEATS2, TBX1, TCF20, SLC22A15, PARS2, SLC35C1, SETD5, PHIP, CDKAL1, NECAP1, DYM, TMCO1, UFD1, TBL2, WWOX, HIRA, FAM135B, TRPS1, NIPBL, YWHAG, NUFIP2, SDHD, ACTL6B, SCN3A, SYNE2, UBA5, AP3B2, ALG13, SZT2, SRD5A3, ALDH5A1, SDHB, SDHC, ALMS1, PCGF2, SIM1, SKI, GALNT14, GNPTAB, MED13L, PCDH15, ZBTB16, ARV1, GSPT2, PRDM16, SLC22A3, SEC24C, AARS1, COX3, TRNQ, COL4A2, COX1, COL6A1, COX2, ARSD, ND1, ND4, FLG, ND5, FGFR1, ND6, FGF14, TRNF, FGF12, TRNH, FER, FBN1, BRCA2, MSNP1, CLTC, MEIS2, CAMK2G, GRIN2D, LHX1, CACNA1B, GP1BB, ALDH1A3, GJB2, GJA8, RERE, GJA5, KCNB1, CHRNA1, GATM, KMT2A, KCNA2, GAMT, TRNL1, GUCY1A2, TRNS1, NDP, ATP6V1A, DNM1, EEF1A2, ARVCF, BPTF, NHS, ERBB4, ERG, NELL1, NONO, NAGLU, TRNS2, NAGA, TRNW, CD38, CYFIP1, HTC2, APP, DNTT, MUL1, CBLL2, IL17A, TNF, ARID1B, MBD1, DYRK1A, NOS1, MRC1, MTOR, PVALB, FRAXA, VDR, GRPR, ADORA2A, NCS1, APOE, NLGN4Y, FMR1-IT1, ZNF804A, SYN1, PCDH19, CARS1, RSS, LOC110806262, SMS, SMARCA1, MTR, DBH, GABRG3, DDC, SLC18A1, GRM5, ARX, HOXB1, DRD4, RBM45, AUTS5, DLG4, NCAM1, RAPGEF4, YWHAE, GFAP, GRIP1, TP53, TRIO, TPH1, VIPR2, PCLO, HTT, CACNA1D, HTR2C, CAPS2, KATNAL2, HLA-G, HLA-B, HLA-DPB1, NRAS, CEP290, DLX5, PHB2, CC2D1A, FAAH, DLD, DLG3, ESR2, DLX6, GRIK4, EPHB2, IL22, ZBTB20, IL1RAPL2, DRD2, DPP4, FAM120C, AMBRA1, MBD5, CNR2, GAD2, GPHN, ABCB6, RIMS3, ARHGAP32, CLOCK, CHAT, NLGN2, GLUL, CDH13, CELF6, TOP3B, WASF1, ATP2B2, DNMT1, MIR137, PIK3CD, SOAT1, PAFAH1B1, RIT2, ANK3, SMARCA4, PTPRZ1, LRFN5, SLC12A2, HEPACAM, SNAP25, PIK3CB, PTLS, ACAN, APRT, ACTB, NDN, CLIP1, AMPD1, TCF4, TAC1, MFAP1, CADM2, MAPK1, MFGE8, NIPA1, MEF2A, OPRM1, MTRR, NCAM2, NEGR1, CCL2, ADCY1, CRP, LSG1, CTSB, MIR137HG, MIR124-1, TESC, CTLA4, CTNNB1, SLC52A1, NOTCH2NLA, CSF2, QRSL1, CS, RPP25, C4orf3, TADA1, CHDS3, PCDHB4, CHPT1, ANKS1B, CELF4, SPHK2, CLK2, SLC2A4RG, RETN, CTNNBL1, HCA1, ANKH, NSMCE3, AGTR2, DNAAF3, MYDGF, CMAS, AGT, AGRP, AGER, EAF2, PAG1, ARSI, CNTF, FCRL6, ZNF407, WDR11, CYP1B1, CTSD, HYDIN, ACACA, DMD, FOXP3, TAS2R1, TAS2R3, LINC01672, IL21R, NT5C, DEL11P13, VSX1, NOTCH2NLC, NOTCH2NLB, ABO, MYLPF, ABCA3, STRN4, THRIL, DNASE1L3, CTNNA3, PYCARD, DYNC1H1, LOC102724334, SETD2, THRA1/BTR, MCTS1, SYNSTH, ADHD6, ACHE, MIR486-1, CUX1, LRRN3, GNB1L, ADARB1, CYP2D6, BDNF-AS, CYP11B1, H4C15, CYP21A2, DAB2, TREM2, DCUN1D1, WAC, H2BS1, IL17D, ADA2, ZNF674, DECR1, SCLY, MIR557, ZGLP1, VCX3A, ACP1, SPG21, PCBP4, FOXK1, SENP7, ATP13A4, C5, SIK1, H2BC12, COMMD1, ZNF385B, EBPL, NTNG2, KIRREL3, TMEM185A, SRRM4, MEGF10, RNF135, PPP1R1B, RPS10P2, UPP2, CTTNBP2, FERMT3, FAM107B, CACNB2, TTC25, PCDH11Y, APBA2, NETO1, DIAPH3, NDEL1, STMN4, BST1, AREG, AS3MT, SYTL4, ASTN1, ASL, OMA1, H4-16, AVPR2, TUBGCP5, ADGRB3, MBD6, AGBL1, PGLYRP2, CEP41, DUSP15, TNFRSF17, RHOT2, XIRP2, OPN1SW, HTR7P1, CNTNAP5, BMPR2, SNX29, FAM43A, CHURC1, NOBOX, UBXN11, ARNTL, DOCK11, SPX, SRCIN1, ABCA13, TSHZ3, CLSTN2, CDH11, AMY1B, AMY1A, RIC8A, PPCDC, IL21, ZNF410, FBXO15, LRRC4C, CDH15, VPS18, PREX1, CPED1, CDK5, ATOH7, CECR, LRFN2, MRTFB, ALDH2, ALB, ATD, IL27, CHRM3, KCTD13, SLC12A5, CDH8, TOR3A, CDH7, CD69, CALB1, CALB2, VPS13B, CAST, LINGO2, MCPH1, CASP3, SH3TC2, SERPINH1, SLC35G1, CARS2, CBS, FA2H, MLPH, CUEDC2, DNAAF4, VKORC1, WNK3, CD5L, ANK2, CD40LG, SIL1, ANK1, ZNF778, AMY1C, DAGLA, WDFY3, DESI1, IL1B, IL18, IL16, IL9, CXCL8, TERF1, TERT, TG, SYP, TGFB1, TH, THBS1, THRA, TLL1, TSPAN4, TAL1, SYN2, TPTE, SRC, KCNJ10, SOD1, SOD2, SOS1, KCNJ1, SP1, SRY, INSR, SST, SSTR5, STAT3, ITIH3, ITGAV, ITGA6, TNC, TRH, SNCG, RASSF7, PXDN, HGF, HFE, FZD3, SEM1, GLRA3, HCCS, LRP8, AKAP1, BAS, DGCR6, H2AZ1, USP9X, H1-4, NRG1, UBE2K, TRPC6, HP, HTR7, HTR4, HTR1A, TXN, HPD, UCP3, UROD, MKRN3, HOXD@, HMGN1, WT1, HLA-DPA1, XPO1, HLA-DOA, SNRNP70, SNCB, DNMT3A, PPP2R5D, NDUFA5, PENK, PIGH, PLP1, PPARD, PPARG, MAPK7, PCDH9, PRODH, MTHFD1, PSD, PTPRF, PURA, RAB3A, NEDD4, NEUROG1, RARA, NPTX2, NTS, NUP98, NPY1R, OCRL, OGG1, OMG, OTX1, NFE2L2, NPY, NOTCH1, PCSK6, NFKBIL1, NFIC, PAX3, MT3, RASGRF1, SMARCA2, LAMC2, LTA, LMX1B, SHMT1, SHMT2, LEPR, SLC1A1, L1CAM, SDC2, SLC6A3, KRT7, KIR3DL1, SLC12A3, KIR2DS1, KCNQ2, MAFD2, CXCL5, OPN1LW, RORC, REN, UPF1, MT1A, RFC1, MOV10, MMP9, RYR2, CCL22, RYR3, S100B, MEST, MBP, MAP2, CCL17, GUK1, H4C9, H4C1, FGFR2, CHP1, FOLR1, DLGAP4, NTNG1, FOLH1, FLT4, FAN1, FOSL2, NT5C2, MAST1, NPY5R, MYT1L, SETD1B, KDM4C, DCTN3, PTENP1, FAP, CHL1, ATP8A1, DEAF1, KAT5, GNB5, GABRG1, GABPA, XRCC6, ZNF277, LYVE1, EHD1, RAB40B, SLC27A4, SLC27A3, SPACA9, POGZ, PHF8, H4C4, GREM1, ELAVL2, PLEKHG3, SETBP1, EIF4EBP2, EBF1, DSCAM, COPG2, ENO2, AKAP8L, DPYSL2, ACAD8, DPP6, AGO2, CNTN6, ELK3, PART1, DIP2A, SYNM, ACSL4, ARHGEF9, FABP7, MCF2L, CUX2, F2RL1, CRTC1, EPS8, EZH2, SLC35A3, MAPK8IP2, PSD4, SH3BP4, SHC2, SEMA3A, AKR1A1, BCAS2, AP1S2, MPDZ, BANF1, GRM7, GRM1, CCN6, NR1I2, GRIN1, KLF7, CACNA1G, GRIK1, GRID2, GRIA2, GPR37, PKD2L1, EIF3A, GRP, AKAP8, H4C5, H4C6, H4C12, H4C11, H4C3, H4C8, H4C2, H4C13, CASK, H4C14, GNPAT, CUL3, GSK3B, CNTNAP1, DENR, GPR35, ARTN, ARHGEF2, GCG, BMS1, PTDSS1, RNF40, GEM, GDNF, SETDB1, RBM8A, XPR1, GATA4, SLC12A6, AKT3, RANBP9, TSPAN32, SPRY3, GH1, GLDC, MACROH2A1, GLP1R, MAGED1, GLRA2, HOMER1, ABCG2, GLRB, GLS, ADIPOQ, GMDS, LHX2, TAOK2, TRIP12, CYTH1, GOT2, STIN2-VNTR
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Benzodiazepine Dependence
Wikipedia
This was demonstrated by the ability to avoid the withdrawal syndrome by the administration of AMPA antagonists. ... The withdrawal syndrome from benzodiazepines can range from a mild and short-lasting syndrome to a prolonged and severe syndrome. ... "Benzodiazepine dependence" . Adverse Syndromes and Psychiatric Drugs: A clinical guide . ... "Benzodiazepine dependence: focus on withdrawal syndrome". Ann Pharm Fr . 67 (6): 408–13. doi : 10.1016/j.pharma.2009.07.001 . ... "Benzodiazepine dependence: focus on withdrawal syndrome". Ann Pharm Fr . 67 (6): 408–13. doi : 10.1016/j.pharma.2009.07.001 .
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Diverticulitis
Wikipedia
Specialty General surgery Symptoms Abdominal pain , fever , nausea , diarrhea , constipation , blood in the stool [1] Complications Abscess , fistula , bowel perforation [1] Usual onset Sudden, age > 50 [1] Causes Uncertain [1] Risk factors Obesity , lack of exercise, smoking , family history, nonsteroidal anti-inflammatory drugs [1] [2] Diagnostic method Blood tests, CT scan , colonoscopy , lower gastrointestinal series [1] Differential diagnosis Irritable bowel syndrome [2] Prevention Mesalazine , rifaximin [2] Treatment Antibiotics , liquid diet, hospital admission [1] Frequency 3.3% (developed world) [1] [3] Diverticulitis , specifically colonic diverticulitis , is a gastrointestinal disease characterized by inflammation of abnormal pouches— diverticula —which can develop in the wall of the large intestine . [1] Symptoms typically include lower abdominal pain of sudden onset, but the onset may also occur over a few days. [1] There may also be nausea ; and diarrhea or constipation . [1] Fever or blood in the stool suggests a complication. [1] Repeated attacks may occur. [2] The causes of diverticulitis are uncertain. [1] Risk factors may include obesity , lack of exercise, smoking , a family history of the disease, and use of nonsteroidal anti-inflammatory drugs (NSAIDs). [1] [2] The role of a low fiber diet as a risk factor is unclear. [2] Having pouches in the large intestine that are not inflamed is known as diverticulosis . [1] Inflammation occurs in between 10% and 25% at some point in time, and is due to a bacterial infection . [2] [4] Diagnosis is typically by CT scan , though blood tests, colonoscopy , or a lower gastrointestinal series may also be supportive. [1] The differential diagnoses include irritable bowel syndrome . [2] Preventive measures include altering risk factors such as obesity, inactivity, and smoking. [2] Mesalazine and rifaximin appear useful for preventing attacks in those with diverticulosis. [2] Avoiding nuts and seeds as a preventive measure is no longer recommended since there is no evidence these play a role in initiating inflammation in diverticula. [1] [5] For mild diverticulitis, antibiotics by mouth and a liquid diet are recommended. [1] For severe cases, intravenous antibiotics, hospital admission, and complete bowel rest may be recommended. [1] Probiotics are of unclear value. [2] Complications such as abscess formation, fistula formation, and perforation of the colon may require surgery. [1] The disease is common in the Western world and uncommon in Africa and Asia. [1] In the Western world about 35% of people have diverticulosis while it affects less than 1% of those in rural Africa, [4] and 4 to 15% of those may go on to develop diverticulitis. [3] In North America and Europe the abdominal pain is usually on the left lower side (sigmoid colon), while in Asia it is usually on the right (ascending colon). [2] [6] The disease becomes more frequent with age, being particularly common in those over the age of 50. [1] It has also become more common in all parts of the world. [2] In 2003 in Europe, it resulted in approximately 13,000 deaths. [2] It is the most frequent anatomic disease of the colon. [2] Costs associated with diverticular disease were around US $2.4 billion a year in the United States in 2013. [2] Contents 1 Signs and symptoms 1.1 Complications 2 Causes 2.1 Diet 3 Pathology 4 Diagnosis 4.1 Classification by severity 4.2 Differential diagnoses 5 Treatment 5.1 Diet 5.2 Antibiotics 5.3 Surgery 5.3.1 Technique 5.3.2 Approach 5.3.3 Maneuvers 5.3.4 Bowel resection with colostomy 6 Epidemiology 7 References 8 External links Signs and symptoms [ edit ] Diverticulitis typically presents with lower quadrant abdominal pain of a sudden onset. [1] In North America and Europe the abdominal pain is usually on the left lower side (sigmoid colon), while in Asia it is usually on the right (ascending colon). [2] [6] There may also be fever , nausea , diarrhea or constipation , and blood in the stool. [1] Complications [ edit ] This section does not cite any sources . ... The most recent and widely accepted is as follows: [17] Stage 0 – asymptomatic diverticulosis Stage 1a – uncomplicated diverticulitis Stage 1b – diverticulitis with phlegmonous peridiverticulitis Stage 2a – diverticulitis with concealed perforation, and abscess with a diameter of one centimeter or less Stage 2b – diverticulitis with abscess greater than one centimeter Stage 3a – diverticulitis with symptoms but without complications Stage 3b – relapsing diverticulitis without complications Stage 3c – relapsing diverticulitis with complications The severity of diverticulitis can be radiographically graded by the Hinchey Classification . [18] Differential diagnoses [ edit ] The differential diagnoses include colon cancer , inflammatory bowel disease , ischemic colitis , and irritable bowel syndrome , as well as a number of urological and gynecological processes. ... External links [ edit ] Classification D ICD - 10 : K57 ICD - 9-CM : 562 MeSH : D004238 DiseasesDB : 3876 External resources MedlinePlus : 000257 eMedicine : med/578 Diverticulosis and diverticulitis at NIDDK Diverticulitis at Mayo Clinic Staging of Acute Diverticulitis online calc v t e Diseases of the digestive system Upper GI tract Esophagus Esophagitis Candidal Eosinophilic Herpetiform Rupture Boerhaave syndrome Mallory–Weiss syndrome UES Zenker's diverticulum LES Barrett's esophagus Esophageal motility disorder Nutcracker esophagus Achalasia Diffuse esophageal spasm Gastroesophageal reflux disease (GERD) Laryngopharyngeal reflux (LPR) Esophageal stricture Megaesophagus Esophageal intramural pseudodiverticulosis Stomach Gastritis Atrophic Ménétrier's disease Gastroenteritis Peptic (gastric) ulcer Cushing ulcer Dieulafoy's lesion Dyspepsia Pyloric stenosis Achlorhydria Gastroparesis Gastroptosis Portal hypertensive gastropathy Gastric antral vascular ectasia Gastric dumping syndrome Gastric volvulus Buried bumper syndrome Gastrinoma Zollinger–Ellison syndrome Lower GI tract Enteropathy Small intestine ( Duodenum / Jejunum / Ileum ) Enteritis Duodenitis Jejunitis Ileitis Peptic (duodenal) ulcer Curling's ulcer Malabsorption : Coeliac Tropical sprue Blind loop syndrome Small bowel bacterial overgrowth syndrome Whipple's Short bowel syndrome Steatorrhea Milroy disease Bile acid malabsorption Large intestine ( Appendix / Colon ) Appendicitis Colitis Pseudomembranous Ulcerative Ischemic Microscopic Collagenous Lymphocytic Functional colonic disease IBS Intestinal pseudoobstruction / Ogilvie syndrome Megacolon / Toxic megacolon Diverticulitis / Diverticulosis / SCAD Large and/or small Enterocolitis Necrotizing Gastroenterocolitis IBD Crohn's disease Vascular : Abdominal angina Mesenteric ischemia Angiodysplasia Bowel obstruction : Ileus Intussusception Volvulus Fecal impaction Constipation Diarrhea Infectious Intestinal adhesions Rectum Proctitis Radiation proctitis Proctalgia fugax Rectal prolapse Anismus Anal canal Anal fissure / Anal fistula Anal abscess Hemorrhoid Anal dysplasia Pruritus ani GI bleeding Blood in stool Upper Hematemesis Melena Lower Hematochezia Accessory Liver Hepatitis Viral hepatitis Autoimmune hepatitis Alcoholic hepatitis Cirrhosis PBC Fatty liver NASH Vascular Budd–Chiari syndrome Hepatic veno-occlusive disease Portal hypertension Nutmeg liver Alcoholic liver disease Liver failure Hepatic encephalopathy Acute liver failure Liver abscess Pyogenic Amoebic Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Hemochromatosis Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis Adenomyomatosis Postcholecystectomy syndrome Porcelain gallbladder Bile duct / Other biliary tree Cholangitis Primary sclerosing cholangitis Secondary sclerosing cholangitis Ascending Cholestasis / Mirizzi's syndrome Biliary fistula Haemobilia Common bile duct Choledocholithiasis Biliary dyskinesia Sphincter of Oddi dysfunction Pancreatic Pancreatitis Acute Chronic Hereditary Pancreatic abscess Pancreatic pseudocyst Exocrine pancreatic insufficiency Pancreatic fistula Other Hernia Diaphragmatic Congenital Hiatus Inguinal Indirect Direct Umbilical Femoral Obturator Spigelian Lumbar Petit's Grynfeltt-Lesshaft Undefined location Incisional Internal hernia Richter's Peritoneal Peritonitis Spontaneous bacterial peritonitis Hemoperitoneum Pneumoperitoneum
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Catsper-Related Male Infertility
Gene_reviews
CATSPER- related male infertility results from abnormalities in sperm and can be either CATSPER- related nonsyndromic male infertility (NSMI) or the deafness-infertility syndrome (DIS) when associated with non-progressive prelingual sensorineural hearing loss. ... Clinical Characteristics Clinical Description CATSPER -related male infertility includes CATSPER- related nonsyndromic male infertility (NSMI) and the deafness-infertility syndrome (DIS) [Nikpoor et al 2004, Clapham & Garbers 2005, Benoff et al 2007, Hildebrand et al 2010]. ... Females homozygous for the CATSPER1 pathogenic variant and all heterozygous individuals within a family have normal fertility. Deafness-Infertility Syndrome (DIS) Infertility. All males homozygous for CATSPER2-STRC deletion are infertile. ... Zhang and colleagues designated this new syndromic form of hearing loss deafness-infertility syndrome (DIS). ... Nomenclature Deafness-infertility syndrome is also known as sensorineural deafness and male infertility.
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Intrauterine Hypoxia
Wikipedia
Infant respiratory distress syndrome $45,542 $138,224 2. Premature birth and low birth weight $44,490 $119,389 6. ... "[Intrauterine hypoxia and sudden infant death syndrome]". Acta Medica Croatica . 56 (3): 109–18. ... "Chronic fetal hypoxia and sudden infant death syndrome: interaction between maternal smoking and low hematocrit during pregnancy". ... S2CID 16661101 . ^ Gogiia TE (November 2005). "[Risk of iugr syndrome development during preeclampsia of the pregnant]". ... PMID 12533965 . ^ Habek D, Habek JC, Ivanisević M, Djelmis J (2002). "Fetal tobacco syndrome and perinatal outcome". Fetal Diagnosis and Therapy . 17 (6): 367–71. doi : 10.1159/000065387 .
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Impulse-Control Disorder
Wikipedia
The efficiency of cognitive behavior therapy for compulsive buying is not truly determined yet; however, common techniques for the treatment include exposure and response prevention , relapse prevention , cognitive restructuring , covert sensitization , and stimulus control . [16] See also [ edit ] Behavioral addiction Body-focused repetitive behavior Child pyromaniac Dopamine dysregulation syndrome References [ edit ] ^ a b c "Highlights of Changes from DSM-IV-TR to DSM-5" (PDF) . ... "Impulse-control disorders in gilles de la tourette syndrome". The Journal of Neuropsychiatry and Clinical Neurosciences . 24 (1): 16–27. doi : 10.1176/appi.neuropsych.10010013 . ... External links [ edit ] Classification D ICD - 10 : F63 ICD - 9-CM : 312.3 MeSH : D007174 v t e Mental and behavioral disorders Adult personality and behavior Gender dysphoria Ego-dystonic sexual orientation Paraphilia Fetishism Voyeurism Sexual maturation disorder Sexual relationship disorder Other Factitious disorder Munchausen syndrome Intermittent explosive disorder Dermatillomania Kleptomania Pyromania Trichotillomania Personality disorder Childhood and learning Emotional and behavioral ADHD Conduct disorder ODD Emotional and behavioral disorders Separation anxiety disorder Movement disorders Stereotypic Social functioning DAD RAD Selective mutism Speech Stuttering Cluttering Tic disorder Tourette syndrome Intellectual disability X-linked intellectual disability Lujan–Fryns syndrome Psychological development ( developmental disabilities ) Pervasive Specific Mood (affective) Bipolar Bipolar I Bipolar II Bipolar NOS Cyclothymia Depression Atypical depression Dysthymia Major depressive disorder Melancholic depression Seasonal affective disorder Mania Neurological and symptomatic Autism spectrum Autism Asperger syndrome High-functioning autism PDD-NOS Savant syndrome Dementia AIDS dementia complex Alzheimer's disease Creutzfeldt–Jakob disease Frontotemporal dementia Huntington's disease Mild cognitive impairment Parkinson's disease Pick's disease Sundowning Vascular dementia Wandering Other Delirium Organic brain syndrome Post-concussion syndrome Neurotic , stress -related and somatoform Adjustment Adjustment disorder with depressed mood Anxiety Phobia Agoraphobia Social anxiety Social phobia Anthropophobia Specific social phobia Specific phobia Claustrophobia Other Generalized anxiety disorder OCD Panic attack Panic disorder Stress Acute stress reaction PTSD Dissociative Depersonalization disorder Dissociative identity disorder Fugue state Psychogenic amnesia Somatic symptom Body dysmorphic disorder Conversion disorder Ganser syndrome Globus pharyngis Psychogenic non-epileptic seizures False pregnancy Hypochondriasis Mass psychogenic illness Nosophobia Psychogenic pain Somatization disorder Physiological and physical behavior Eating Anorexia nervosa Bulimia nervosa Rumination syndrome Other specified feeding or eating disorder Nonorganic sleep Hypersomnia Insomnia Parasomnia Night terror Nightmare REM sleep behavior disorder Postnatal Postpartum depression Postpartum psychosis Sexual dysfunction Arousal Erectile dysfunction Female sexual arousal disorder Desire Hypersexuality Hypoactive sexual desire disorder Orgasm Anorgasmia Delayed ejaculation Premature ejaculation Sexual anhedonia Pain Nonorganic dyspareunia Nonorganic vaginismus Psychoactive substances, substance abuse and substance-related Drug overdose Intoxication Physical dependence Rebound effect Stimulant psychosis Substance dependence Withdrawal Schizophrenia , schizotypal and delusional Delusional Delusional disorder Folie à deux Psychosis and schizophrenia-like Brief reactive psychosis Schizoaffective disorder Schizophreniform disorder Schizophrenia Childhood schizophrenia Disorganized (hebephrenic) schizophrenia Paranoid schizophrenia Pseudoneurotic schizophrenia Simple-type schizophrenia Other Catatonia Symptoms and uncategorized Impulse control disorder Klüver–Bucy syndrome Psychomotor agitation Stereotypy v t e Borderline personality disorder General Dimensional models of personality disorders Impulse control disorders Trauma model of mental disorders Misdiagnosis of borderline personality disorder Symptoms and behaviors Dissociation Eating disorders Emotional dysregulation Feelings of emptiness Hypersexuality Idealization and devaluation Impulsivity Mood swings Projection Self-harm Splitting Suicidal ideation Management Dialectical behavior therapy Dynamic deconstructive psychotherapy McLean Hospital Mentalization-based treatment Schema therapy Social psychiatry Transference focused psychotherapy Family challenges BPDFamily (support group) Codependency Complex PTSD Emotional blackmail Family estrangement Personal boundariesDRD3, DRD2, FOSB, SLC6A3, IL6, FLG, IL6R, SLC6A8, CALCR, IL1B, GRIN2B, TNF, CALR, COMT, ASXL1, OXER1, YWHAE, FZD4, VN1R17P, BAG3, MCF2L, SF3B1, LPAR3, REM1, IL22, SCLY, TET2, DSCAML1, LGR6, MARCHF7, WDR26, MRGPRX3, TAL1, MRGPRX1, ANKK1, MRGPRX4, GPR151, IL23R, GPRC6A, APRT, RYR2, ST2, SOD2, ENTPD1, GADD45A, NQO1, DRD1, DRD4, GNAS, CXCL2, HTR2A, HTR2C, KRT7, LMNA, LRP2, MFAP1, NOS1, NPPB, OPRM1, PAFAH1B1, PIM1, PLAT, PLCD1, PLCG1, CCL2, SLN, GPR166P
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Complications Of Traumatic Brain Injury
Wikipedia
Symptoms that may occur after a concussion – a minor form of traumatic brain injury – are referred to as post-concussion syndrome . Contents 1 Effects on unconsciousness 2 Cognitive deficits 3 Communication problems 4 Sensory deficits 5 Emotional and behavioral problems 6 Physical complications 7 See also 8 References Effects on unconsciousness [ edit ] Generally, there are six abnormal states of consciousness that can result from a TBI: Stupor is a state of partial or near complete unconsciousness in which the patient is lethargic, immobile, and has a reduced response to stimuli. [3] Coma is a state in which the patient is totally unconscious and cannot be aroused even with strong stimuli. [4] Persistent vegetative state is a condition in which awake patients are unconscious and unaware of their surroundings and the cerebral cortex is not functioning. [5] A vegetative state can result from diffuse injury to the cerebral hemispheres of the brain without damage to the lower brain and brainstem. ... Two common hormonal complications of TBI are syndrome of inappropriate secretion of antidiuretic hormone and hypothyroidism . [1] Another common problem is spasticity . ... Retrieved 2008-11-06 . ^ a b " Locked-in syndrome " at Dorland's Medical Dictionary . ^ a b " Brain death " at Dorland's Medical Dictionary . ^ a b c Arlinghaus KA, Shoaib AM, Price TR (2005). ... "Definition, diagnosis, and forensic implications of postconcussional syndrome" . Psychosomatics . 46 (3): 195–202. doi : 10.1176/appi.psy.46.3.195 . ... Retrieved 2017-01-31 . v t e Neurotrauma Traumatic brain injury Intracranial hemorrhage Intra-axial Intraparenchymal hemorrhage Intraventricular hemorrhage Extra-axial Subdural hematoma Epidural hematoma Subarachnoid hemorrhage Brain herniation Cerebral contusion Cerebral laceration Concussion Post-concussion syndrome Second-impact syndrome Dementia pugilistica Chronic traumatic encephalopathy Diffuse axonal injury Abusive head trauma Penetrating head injury Spinal cord injury Anterior spinal artery syndrome Brown-Séquard syndrome Cauda equina syndrome Central cord syndrome Paraplegia Posterior cord syndrome Spinal cord injury without radiographic abnormality Tetraplegia (Quadriplegia) Peripheral nerves Nerve injury Peripheral nerve injury classification Wallerian degeneration Injury of accessory nerve Brachial plexus injury Traumatic neuroma
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Acute Pericarditis
Wikipedia
., systemic lupus erythematosus ), cancer , or involve an inflammatory reaction of the pericardium following trauma to the heart such as after a heart attack such as Dressler's syndrome . [1] Familial mediterranean fever and TNF receptor associated periodic syndrome are rare inherited autoimmune diseases capable of causing recurring episodes of acute pericarditis. [1] Pathophysiology [ edit ] Clinical presentation of diseases of pericardium may vary between: [2] [3] Acute and recurrent pericarditis Pericardial effusion without major hemodynamic compromise Cardiac tamponade Constrictive pericarditis Effusive-constrictive pericarditis Diagnosis [ edit ] ECG showing slight ST elevation in many leads congruent with pericarditis For acute pericarditis to formally be diagnosed, two or more of the following criteria must be present: chest pain consistent with a diagnosis of acute pericarditis (sharp chest pain worsened by breathing in or a cough), a pericardial friction rub , a pericardial effusion , and changes on electrocardiogram (ECG) consistent with acute pericarditis. [1] A complete blood count may show an elevated white count and a serum C-reactive protein may be elevated. ... In addition, Spodick's sign may also serve as an important distinguishing electrocardiographic tool between the acute pericarditis and acute coronary syndrome. The presence of a classical Spodick's sign is often a giveaway to the diagnosis. ... External links [ edit ] Classification D ICD - 10 : I30 ICD - 9-CM : 420 External resources MedlinePlus : 000182 eMedicine : med/1781 v t e Cardiovascular disease (heart) Ischaemic Coronary disease Coronary artery disease (CAD) Coronary artery aneurysm Spontaneous coronary artery dissection (SCAD) Coronary thrombosis Coronary vasospasm Myocardial bridge Active ischemia Angina pectoris Prinzmetal's angina Stable angina Acute coronary syndrome Myocardial infarction Unstable angina Sequelae hours Hibernating myocardium Myocardial stunning days Myocardial rupture weeks Aneurysm of heart / Ventricular aneurysm Dressler syndrome Layers Pericardium Pericarditis Acute Chronic / Constrictive Pericardial effusion Cardiac tamponade Hemopericardium Myocardium Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Tachycardia-induced Restrictive Loeffler endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular dysplasia Endocardium / valves Endocarditis infective endocarditis Subacute bacterial endocarditis non-infective endocarditis Libman–Sacks endocarditis Nonbacterial thrombotic endocarditis Valves mitral regurgitation prolapse stenosis aortic stenosis insufficiency tricuspid stenosis insufficiency pulmonary stenosis insufficiency Conduction / arrhythmia Bradycardia Sinus bradycardia Sick sinus syndrome Heart block : Sinoatrial AV 1° 2° 3° Intraventricular Bundle branch block Right Left Left anterior fascicle Left posterior fascicle Bifascicular Trifascicular Adams–Stokes syndrome Tachycardia ( paroxysmal and sinus ) Supraventricular Atrial Multifocal Junctional AV nodal reentrant Junctional ectopic Ventricular Accelerated idioventricular rhythm Catecholaminergic polymorphic Torsades de pointes Premature contraction Atrial Junctional Ventricular Pre-excitation syndrome Lown–Ganong–Levine Wolff–Parkinson–White Flutter / fibrillation Atrial flutter Ventricular flutter Atrial fibrillation Familial Ventricular fibrillation Pacemaker Ectopic pacemaker / Ectopic beat Multifocal atrial tachycardia Pacemaker syndrome Parasystole Wandering atrial pacemaker Long QT syndrome Andersen–Tawil Jervell and Lange-Nielsen Romano–Ward Cardiac arrest Sudden cardiac death Asystole Pulseless electrical activity Sinoatrial arrest Other / ungrouped hexaxial reference system Right axis deviation Left axis deviation QT Short QT syndrome T T wave alternans ST Osborn wave ST elevation ST depression Strain pattern Cardiomegaly Ventricular hypertrophy Left Right / Cor pulmonale Atrial enlargement Left Right Athletic heart syndrome Other Cardiac fibrosis Heart failure Diastolic heart failure Cardiac asthma Rheumatic fever
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Juvenile Myelomonocytic Leukemia
Wikipedia
The name JMML now encompasses all diagnoses formerly referred to as juvenile chronic myeloid leukemia (JCML), chronic myelomonocytic leukemia of infancy , and infantile monosomy 7 syndrome . The average age of patients at diagnosis is 2 years old. ... L. (2010). "Childhood myelodysplastic syndrome: Focus on the approach to diagnosis and treatment of juvenile myelomonocytic leukemia" . ... "Myeloproliferative disorder in Noonan syndrome". Journal of Pediatric Hematology/Oncology . 33 (1): e43–5. doi : 10.1097/MPH.0b013e3181e7571e . ... "Making sense of the myelodysplastic/myeloproliferative neoplasms overlap syndromes". Current Opinion in Hematology . 21 (2): 131–40. doi : 10.1097/MOH.0000000000000021 . ... European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)". Blood . 89 (10): 3534–43.KDM6A, TET2, ETV6, DNMT3A, PDGFRB, EZH2, SRSF2, ASXL1, KIT, JAK2, BCR, SETBP1, RUNX1, CD34, KRAS, ABL1, CBL, CSF2, KMT2A, FLT3, NRAS, HIP1, FANCB, SF3B1, PARP1, IL3RA, U2AF1, HRAS, GFM1, RET, FGFR1OP, MEFV, GATA2, MYC, BAP1, FCGR3B, FCGR3A, TNF, IL10, NPM1, MAP2K7, NUP98, RABEP1, IL3, CNTNAP1, FIP1L1, CSF3R, TP53, LINC01152, MOGS, TMED7-TICAM2, TICAM2, YWHAE, YY1, VEGFA, U2AF1L5, RGPD2, THY1, THPO, PPP1R11, SOAT1, H3P23, SCT, ROS1, ELL, ZNRD2, SMC1A, NRP2, TET3, MLKL, MIR142, CBLL2, PDCD1LG2, MIR150, MUL1, XYLT2, PCBP4, PAG1, ETNK1, MIR223, MIR424, BCL11A, TRIM33, DDX41, TMED7, CD274, DLL1, RARS1, KDM6B, KAT7, DCTN6, PRR14L, IL32, OPN1LW, NF1, PTPRC, CREBBP, FRA16B, FLT3LG, FGFR1, F3, MECOM, ERCC1, EPO, EPHB2, EIF4E, EGR2, CYBB, CTLA4, CSF1, COL11A2, GP1BA, CCR7, CDKN2A, CDKN1A, CD68, CD14, CD6, BRAF, BLVRB, BCHE, ARG1, BIRC5, APEX1, ANPEP, FUT4, GRB2, PTPN11, MTTP, PSMD9, PSMB6, MAPK1, PDGFRA, PDE4A, PRKN, PAFAH1B1, PEBP1, ACHE, NELL2, NBN, MYH10, MYB, KITLG, CXCL1, LYZ, JUN, ITGAM, IL18, IL4, IL1B, IGF2, IFI27, ID1, HTR1B, AGFG2, HOXA9, HTT, H3P10
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Biliary Atresia
Wikipedia
The biliary atresia phenotype caused by congenital aflatoxicosis in GST M1 deficient neonates is named Kotb disease. [5] Syndromic biliary atresia (e.g. Biliary Atresia Splenic Malformation (BASM)) has been associated with certain genes (e.g. ... In approximately 10% of cases, other anomalies may be associated with biliary atresia. The most common of these syndromic forms is BASM [19] and might include heart lesions, polysplenia , situs inversus , absent venae cavae , and a preduodenal portal vein . [20] Progressive cirrhosis is associated with signs and symptoms of portal hypertension, such as esophagogastric varix bleeding, hypersplenism , hepatorenal syndrome , and hepatopulmonary syndrome . [ citation needed ] In an Egyptian study, abnormally high levels of aflatoxin B1 and to a lesser extent aflatoxin B2 was found in liver tissue and blood of all neonates suffering from biliary atresia. ... "Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome" . Hepatology . 70 (3): 899–910. doi : 10.1002/hep.30515 . ... "Biliary atresia splenic malformation syndrome: an etiologic and prognostic subgroup". ... "The biliary atresia splenic malformation syndrome: A 28-year single-center retrospective study".HAMP, GPC1, MIR145, SOX17, EFEMP1, GATA6, ADD3-AS1, LY86-AS1, ZDHHC24, RFX6, CBR4, HPCAL1, ERCC4, WDR70, BBS1, LINC02492, RBFOX1, ZIC3, RNU6-484P, MMP7, JAG1, ADD3, IFNG, LOC102724197, GGTLC1, VEGFA, PROM1, IL33, GGTLC3, TLR7, NOTCH2, CD14, GGTLC4P, GGT2, CCN2, FOXA2, GGT1, GGTLC5P, MMP2, GPT, LOXL2, IL6, IL4, DNMT3A, TNFRSF12A, ALB, VIM, SPP1, ICAM1, MIR29C, STAT1, IL10, LGALS3BP, MX1, IL18, EGF, HMGB1, TLR2, TGFB1, TIMP1, MIR200B, MBD4, IL32, MIR4429, TNFSF10, MIR19B1, ABCB11, NR0B2, XPNPEP1, ADIPOQ, USF2, TNF, TLR3, TGFB2, TEK, HNF1B, CD163, INVS, FGF19, STAT6, MIR140, TICAM2, MIR222, MIR499A, RHOV, PPM1K, MTG1, LMLN, PDCD1LG2, SLC26A6, TMED7-TICAM2, CFC1, MIR4689, SPRY2, TLR8, TMED7, FOXP3, CD274, FGF21, NOC2L, SMG1, CHP1, DCTN6, IVNS1ABP, ARID3B, ZNRD2, STX3, PTPN11, STAT3, HGFAC, FCGR3A, FCGR3B, FGFR4, GHR, GLI2, GSTA1, HGF, HIF1A, ST2, HLA-A, FOXA3, ONECUT1, HES1, HSPA4, HSP90AA1, IFI27, F2, EPHB2, EPAS1, EGFR, ANGPT1, ANGPT2, ANXA2, ANXA2P3, ARF6, CASP1, CD68, CDKN1B, CREB1, CTNNB1, CX3CR1, CYBB, CYP7A1, DNMT1, DNMT3B, IGF1, IGFBP1, IGFBP3, NODAL, PDGFA, ENPP2, MAPK1, MAPK3, PSMD9, RDX, RRAS, SRL, CCL2, CCL20, CX3CL1, SELE, SHH, SOX9, SPINT1, PCK1, NCAM1, CXCL8, MIF, CXCR2, IL13, CXCL10, IRF5, IRF7, ITGAL, ITGB2, ITGB5, ITGB8, KRT7, KRT19, LAMC2, EPCAM, SMAD3, MBD1, H3P23
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Body Dysmorphic Disorder
Wikipedia
Mental disorder Body dysmorphic disorder Other names Body dysmorphia, dysmorphic syndrome, dysmorphophobia A cartoon of a patient with body dysmorphia looking in a mirror, seeing a distorted image of himself Specialty Psychiatry , clinical psychology Body dysmorphic disorder ( BDD ), occasionally still called dysmorphophobia , is a mental disorder characterized by the obsessive idea that some aspect of one's own body part or appearance is severely flawed and therefore warrants exceptional measures to hide or fix it. [1] In BDD's delusional variant, the flaw is imagined. [2] If the flaw is actual, its importance is severely exaggerated. [2] Either way, thoughts about it are pervasive and intrusive, and may occupy several hours a day, causing severe distress and impairing one’s otherwise normal activities. ... Advance online publication. https://doi.org/10.1037/ppm0000264 ^ Vats M. Selfie syndrome: An infectious gift of IT to health care. ... External links [ edit ] Classification D ICD - 10 : F45.2 ICD - 10-CM : F45.22 ICD - 9-CM : 300.7 MeSH : D057215 DiseasesDB : 33723 External resources eMedicine : med/3124 Patient UK : Body dysmorphic disorder v t e Mental and behavioral disorders Adult personality and behavior Gender dysphoria Ego-dystonic sexual orientation Paraphilia Fetishism Voyeurism Sexual maturation disorder Sexual relationship disorder Other Factitious disorder Munchausen syndrome Intermittent explosive disorder Dermatillomania Kleptomania Pyromania Trichotillomania Personality disorder Childhood and learning Emotional and behavioral ADHD Conduct disorder ODD Emotional and behavioral disorders Separation anxiety disorder Movement disorders Stereotypic Social functioning DAD RAD Selective mutism Speech Stuttering Cluttering Tic disorder Tourette syndrome Intellectual disability X-linked intellectual disability Lujan–Fryns syndrome Psychological development ( developmental disabilities ) Pervasive Specific Mood (affective) Bipolar Bipolar I Bipolar II Bipolar NOS Cyclothymia Depression Atypical depression Dysthymia Major depressive disorder Melancholic depression Seasonal affective disorder Mania Neurological and symptomatic Autism spectrum Autism Asperger syndrome High-functioning autism PDD-NOS Savant syndrome Dementia AIDS dementia complex Alzheimer's disease Creutzfeldt–Jakob disease Frontotemporal dementia Huntington's disease Mild cognitive impairment Parkinson's disease Pick's disease Sundowning Vascular dementia Wandering Other Delirium Organic brain syndrome Post-concussion syndrome Neurotic , stress -related and somatoform Adjustment Adjustment disorder with depressed mood Anxiety Phobia Agoraphobia Social anxiety Social phobia Anthropophobia Specific social phobia Specific phobia Claustrophobia Other Generalized anxiety disorder OCD Panic attack Panic disorder Stress Acute stress reaction PTSD Dissociative Depersonalization disorder Dissociative identity disorder Fugue state Psychogenic amnesia Somatic symptom Body dysmorphic disorder Conversion disorder Ganser syndrome Globus pharyngis Psychogenic non-epileptic seizures False pregnancy Hypochondriasis Mass psychogenic illness Nosophobia Psychogenic pain Somatization disorder Physiological and physical behavior Eating Anorexia nervosa Bulimia nervosa Rumination syndrome Other specified feeding or eating disorder Nonorganic sleep Hypersomnia Insomnia Parasomnia Night terror Nightmare REM sleep behavior disorder Postnatal Postpartum depression Postpartum psychosis Sexual dysfunction Arousal Erectile dysfunction Female sexual arousal disorder Desire Hypersexuality Hypoactive sexual desire disorder Orgasm Anorgasmia Delayed ejaculation Premature ejaculation Sexual anhedonia Pain Nonorganic dyspareunia Nonorganic vaginismus Psychoactive substances, substance abuse and substance-related Drug overdose Intoxication Physical dependence Rebound effect Stimulant psychosis Substance dependence Withdrawal Schizophrenia , schizotypal and delusional Delusional Delusional disorder Folie à deux Psychosis and schizophrenia-like Brief reactive psychosis Schizoaffective disorder Schizophreniform disorder Schizophrenia Childhood schizophrenia Disorganized (hebephrenic) schizophrenia Paranoid schizophrenia Pseudoneurotic schizophrenia Simple-type schizophrenia Other Catatonia Symptoms and uncategorized Impulse control disorder Klüver–Bucy syndrome Psychomotor agitation Stereotypy
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Pericarditis
Wikipedia
Anaerobic bacteria can also be a rare cause. [13] Fungal pericarditis is usually due to histoplasmosis , or in immunocompromised hosts Aspergillus , Candida , and Coccidioides . [ citation needed ] The most common cause of pericarditis worldwide is infectious pericarditis with tuberculosis. [ citation needed ] Other [ edit ] Idiopathic : No identifiable cause found after routine testing. [4] Autoimmune disease : systemic lupus erythematosus , rheumatic fever , [4] IgG4-related disease [14] [15] Myocardial infarction ( Dressler's syndrome ) [4] Trauma to the heart [4] Uremia ( uremic pericarditis ) [4] Cancer [4] Side effect of some medications , e.g. isoniazid , cyclosporine , hydralazine , warfarin , and heparin Radiation induced [4] Aortic dissection [4] Postpericardiotomy syndrome —such as after CABG surgery [4] Diagnosis [ edit ] Laboratory test [ edit ] Diffuse ST elevation in a young male due to myocarditis / pericarditis An ECG showing pericarditis. ... Acute pericarditis is more common than chronic pericarditis, and can occur as a complication of infections, immunologic conditions, or even as a result of a heart attack (myocardial infarction), as Dressler's syndrome . Chronic pericarditis however is less common, a form of which is constrictive pericarditis . ... External links [ edit ] Pericarditis — Cleveland Clinic Pericarditis — National Library of Medicine Pericarditis — National Heart Lung Blood Institute Classification D ICD - 10 : I01.0 , I09.2 , I30 – I32 ICD - 9-CM : 420.0 , 420.90 , 420.91 , 420.99 , 423.1 , 423.2 MeSH : D010493 DiseasesDB : 9820 SNOMED CT : 3238004 External resources MedlinePlus : 000182 eMedicine : med/1781 emerg/412 v t e Cardiovascular disease (heart) Ischaemic Coronary disease Coronary artery disease (CAD) Coronary artery aneurysm Spontaneous coronary artery dissection (SCAD) Coronary thrombosis Coronary vasospasm Myocardial bridge Active ischemia Angina pectoris Prinzmetal's angina Stable angina Acute coronary syndrome Myocardial infarction Unstable angina Sequelae hours Hibernating myocardium Myocardial stunning days Myocardial rupture weeks Aneurysm of heart / Ventricular aneurysm Dressler syndrome Layers Pericardium Pericarditis Acute Chronic / Constrictive Pericardial effusion Cardiac tamponade Hemopericardium Myocardium Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Tachycardia-induced Restrictive Loeffler endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular dysplasia Endocardium / valves Endocarditis infective endocarditis Subacute bacterial endocarditis non-infective endocarditis Libman–Sacks endocarditis Nonbacterial thrombotic endocarditis Valves mitral regurgitation prolapse stenosis aortic stenosis insufficiency tricuspid stenosis insufficiency pulmonary stenosis insufficiency Conduction / arrhythmia Bradycardia Sinus bradycardia Sick sinus syndrome Heart block : Sinoatrial AV 1° 2° 3° Intraventricular Bundle branch block Right Left Left anterior fascicle Left posterior fascicle Bifascicular Trifascicular Adams–Stokes syndrome Tachycardia ( paroxysmal and sinus ) Supraventricular Atrial Multifocal Junctional AV nodal reentrant Junctional ectopic Ventricular Accelerated idioventricular rhythm Catecholaminergic polymorphic Torsades de pointes Premature contraction Atrial Junctional Ventricular Pre-excitation syndrome Lown–Ganong–Levine Wolff–Parkinson–White Flutter / fibrillation Atrial flutter Ventricular flutter Atrial fibrillation Familial Ventricular fibrillation Pacemaker Ectopic pacemaker / Ectopic beat Multifocal atrial tachycardia Pacemaker syndrome Parasystole Wandering atrial pacemaker Long QT syndrome Andersen–Tawil Jervell and Lange-Nielsen Romano–Ward Cardiac arrest Sudden cardiac death Asystole Pulseless electrical activity Sinoatrial arrest Other / ungrouped hexaxial reference system Right axis deviation Left axis deviation QT Short QT syndrome T T wave alternans ST Osborn wave ST elevation ST depression Strain pattern Cardiomegaly Ventricular hypertrophy Left Right / Cor pulmonale Atrial enlargement Left Right Athletic heart syndrome Other Cardiac fibrosis Heart failure Diastolic heart failure Cardiac asthma Rheumatic feverPRG4, TNFRSF1A, STAT4, IL10, MEFV, CTLA4, PMM2, LACC1, MIF, FAS, NOD2, ERAP1, PRTN3, IL6, PTPN22, TLR4, KLRC4, IL12A, IL12A-AS1, IL23R, HBA2, C4A, CCR1, UBAC2, DNASE1, FCGR2A, FCGR2B, HBA1, HLA-B, HLA-DPA1, HLA-DPB1, HLA-DRB1, TREX1, IL1B, SMUG1, IL1A, TRAF3IP2, NLRP3, CD274, MIR1279, ADA, TRIM21, SNRNP70, PTPN2, PLG, P2RX7, LEP, IL1RN, CRP, CAT, NT5E
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Bruise
Wikipedia
Connective tissue disorders such as Ehlers-Danlos syndrome may cause relatively easy or spontaneous bruising depending on the severity. ... This has the potential to cause compartment syndrome in which the swelling cuts off blood flow to the tissues. ... "Bruises, blood coagulation tests and the battered child syndrome" (PDF) . Singapore Medical Journal . 49 (6): 445–49. ... Davis. ^ Byers PH. Vascular Ehlers-Danlos Syndrome. 1999 Sep 2 [Updated 2019 Feb 21]. ... for kids Bruises in sports Classification D ICD - 10 : S00 - S90 , T14.0 ICD - 9-CM : 920 - 924 MeSH : D003288 DiseasesDB : 31998 SNOMED CT : 125667009 External resources MedlinePlus : 007213 eMedicine : article/88153 v t e General wounds and injuries Abrasions Abrasion Avulsion Blisters Blood blister Coma blister Delayed blister Edema blister Fracture blister Friction blister Sucking blister Bruises Hematoma / Ecchymosis Battle's sign Raccoon eyes Black eye Subungual hematoma Cullen's sign Grey Turner's sign Retroperitoneal hemorrhage Animal bites Insect bite Spider bite Snakebite Other: Ballistic trauma Stab wound Blunt trauma /superficial/ closed Penetrating trauma / open Aerosol burn Burn / Corrosion / Chemical burn Frostbite Occupational injuries Traumatic amputation By region Hand injury Head injury Chest trauma Abdominal trauma v t e Disorders of bleeding and clotting Coagulation · coagulopathy · Bleeding diathesis Clotting By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin G20210A Platelets Sticky platelet syndrome Thrombocytosis Essential thrombocythemia DIC Purpura fulminans Antiphospholipid syndrome Clots Thrombophilia Thrombus Thrombosis Virchow's triad Trousseau sign of malignancy By site Deep vein thrombosis Bancroft's sign Homans sign Lisker's sign Louvel's sign Lowenberg's sign Peabody's sign Pratt's sign Rose's sign Pulmonary embolism Renal vein thrombosis Bleeding By cause Thrombocytopenia Thrombocytopenic purpura : ITP Evans syndrome TM TTP Upshaw–Schulman syndrome Heparin-induced thrombocytopenia May–Hegglin anomaly Platelet function adhesion Bernard–Soulier syndrome aggregation Glanzmann's thrombasthenia platelet storage pool deficiency Hermansky–Pudlak syndrome Gray platelet syndrome Clotting factor Hemophilia A/VIII B/IX C/XI von Willebrand disease Hypoprothrombinemia/II Factor VII deficiency Factor X deficiency Factor XII deficiency Factor XIII deficiency Dysfibrinogenemia Congenital afibrinogenemia Signs and symptoms Bleeding Bruise Hematoma Petechia Purpura Nonthrombocytopenic purpura By site head Epistaxis Hemoptysis Intracranial hemorrhage Hyphema Subconjunctival hemorrhage torso Hemothorax Hemopericardium Pulmonary hematoma abdomen Gastrointestinal bleeding Hemobilia Hemoperitoneum Hematocele Hematosalpinx joint Hemarthrosis
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Paresthesia
Wikipedia
Other causes include conditions such as hyperventilation syndrome and panic attacks . A cold sore outside the mouth (not a canker sore inside the mouth) can be preceded by tingling because a cold sore is caused by herpes simplex virus . ... Joint conditions such as rheumatoid arthritis , psoriatic arthritis , and carpal tunnel syndrome are common sources of paresthesia. ... Neuropathy is also a side effect of some chemotherapies, such as in chemotherapy-induced peripheral neuropathy . [8] Benzodiazepine withdrawal may also cause paresthesia as the drug removal leaves the GABA receptors stripped bare and possibly malformed. [ citation needed ] Chronic paresthesia can sometimes be symptomatic of serious conditions, such as a transient ischemic attack , or autoimmune diseases such as multiple sclerosis , Complex Regional Pain Syndrome or lupus erythematosus . [ citation needed ] The use of fluoroquinolones can also cause paresthesia. [9] Stroke survivors and those with traumatic brain injury (TBI) may experience paresthesia from damage to the central nervous system. [ citation needed ] The varicella zoster virus disease (shingles) can attack nerves causing numbness instead of pain commonly associated with shingles. [ citation needed ] Acroparesthesia [ edit ] Acroparesthesia is severe pain in the extremities, and may be caused by Fabry disease , a type of sphingolipidosis . [10] It can also be a sign of hypocalcemia. [ citation needed ] Dentistry [ edit ] Paresthesia or "persistent anesthesia" is a transient or potentially permanent condition of extended numbness after administration of local anesthesia and the injected anesthetic has terminated. [11] Potential causes include trauma introduced to the nerve sheath during administration of the injection, hemorrhage about the sheath, type of anesthetic used, or administration of anesthetic potentially contaminated with alcohol or sterilizing solutions. [12] Other [ edit ] Other causes may include: Anticonvulsant pharmaceutical drugs , such as topiramate , sultiame , and acetazolamide Anxiety or panic disorder [13] Autonomous sensory meridian response ("ASMR") [14] Benzodiazepine withdrawal syndrome Beta alanine Blood pressure medications Carpal tunnel syndrome Cerebral amyloid angiopathy Chiari malformation Coeliac disease (celiac disease) Complex regional pain syndrome Decompression sickness Dehydration Dextromethorphan (recreational use) Fabry disease Erythromelalgia Fibromyalgia Fluoroquinolone toxicity Guillain–Barré syndrome (GBS) Heavy metals Herpes zoster Hydroxy alpha sanshool , a component of Sichuan peppers Hyperglycemia (high blood sugar ) Hyperkalemia Hyperventilation Hypoglycemia (low blood sugar ) Hypocalcemia , and in turn: Hypermagnesemia , a condition in which hypocalcemia itself is typically observed as a secondary symptom Hypothyroidism Immunodeficiency , such as chronic inflammatory demyelinating polyneuropathy (CIDP) Intravenous administering of strong pharmaceutical drugs acting on the central nervous system (CNS), mainly opioids , opiates , narcotics ; especially in non-medical use ( drug abuse ) Ketorolac Lidocaine poisoning Lomotil Lupus erythematosus Lyme disease Magnesium deficiency , often as a result of long term proton-pump inhibitor use Menopause Mercury poisoning Migraines Multiple sclerosis Nerve compression syndrome Nitrous oxide , long-term exposure [15] Obdormition Oxygen toxicity , especially, breathing oxygen under pressure, such as in scuba diving. ... A tumor or vascular lesion pressed up against the brain or spinal cord can also cause paresthesia. Nerve entrapment syndromes, such as carpal tunnel syndrome, can damage peripheral nerves and cause paresthesia accompanied by pain.PMP22, INS, MTHFR, ALAD, SLC2A1, TP53, TNFRSF1A, TLR4, TK2, THPO, TGFBR2, STAT4, SLC20A2, SLC12A3, SLC12A1, RPS20, SCN4A, TRNL1, POLG, PMS2, PMS1, PIK3CA, PDCD1, NAGLU, NAGA, TRNW, TRNS2, TRNS1, CUBN, PABPN1, KLRC4, STX16, BCL2L2-PABPN1, UBAC2, IL23R, PRRT2, GPR101, AMN, OPA3, FKRP, SEMA4A, SCYL1, TET2, ERAP1, ATL1, RRM2B, STRN4, MLH3, PTPN22, FAN1, SEPTIN9, SLC19A2, SH2B3, MFN2, GNA14, CTDP1, AIP, APP, TRNQ, TRNH, CCR1, HLA-DQB1, HLA-B, HINT1, HBB, MSH6, GNAS, GNA11, GLA, CBLIF, GBE1, TYMP, CLCNKB, HLA-DRB1, LYST, CASR, CAPN3, CAPN1, CALR, CACNA1A, C4A, SERPING1, BMPR1A, CCND1, FAS, TRNF, IL12A-AS1, EPCAM, KCNJ1, MEFV, MPL, MSH2, LIFR, COX1, COX2, KRAS, KIF5A, COX3, MLH1, ND1, ND4, JAK2, IL12A, IL10, ND5, HMBS, ND6, MEN1, ZNF35, CSF2, TTR, LAMC2, GJB1, NTRK1, GPT, GSTP1, TCEA1, HOXB7, ATP1A1, TWIST1, TPM3
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Madarosis
Wikipedia
Other drugs include: propranolol , valproic acid , barbiturates , MMR vaccine , botulinum toxin , epinephrine , antithyroid drugs , anticoagulants , and lipid-lowering drugs Genetics Autoimmune disorders : alopecia areata , discoid lupus erythematosus , chronic cutaneous lupus erythmatosus , Graham-Little syndrome , and Parry Romberg syndrome Other diseases: hypothyroidism , hyperthyroidism , hypoparathyroidism , hypopituitarism , amyloidosis , and Congenital erythropoietic Porphyria [4] ( Günther's disease ) Pathophysiology [ edit ] There are two major pathways. ... External links [ edit ] Classification D ICD - 10 : H02.7 ICD - 9-CM : 374.55 v t e Diseases of the human eye Adnexa Eyelid Inflammation Stye Chalazion Blepharitis Entropion Ectropion Lagophthalmos Blepharochalasis Ptosis Blepharophimosis Xanthelasma Ankyloblepharon Eyelash Trichiasis Madarosis Lacrimal apparatus Dacryoadenitis Epiphora Dacryocystitis Xerophthalmia Orbit Exophthalmos Enophthalmos Orbital cellulitis Orbital lymphoma Periorbital cellulitis Conjunctiva Conjunctivitis allergic Pterygium Pseudopterygium Pinguecula Subconjunctival hemorrhage Globe Fibrous tunic Sclera Scleritis Episcleritis Cornea Keratitis herpetic acanthamoebic fungal Exposure Photokeratitis Corneal ulcer Thygeson's superficial punctate keratopathy Corneal dystrophy Fuchs' Meesmann Corneal ectasia Keratoconus Pellucid marginal degeneration Keratoglobus Terrien's marginal degeneration Post-LASIK ectasia Keratoconjunctivitis sicca Corneal opacity Corneal neovascularization Kayser–Fleischer ring Haab's striae Arcus senilis Band keratopathy Vascular tunic Iris Ciliary body Uveitis Intermediate uveitis Hyphema Rubeosis iridis Persistent pupillary membrane Iridodialysis Synechia Choroid Choroideremia Choroiditis Chorioretinitis Lens Cataract Congenital cataract Childhood cataract Aphakia Ectopia lentis Retina Retinitis Chorioretinitis Cytomegalovirus retinitis Retinal detachment Retinoschisis Ocular ischemic syndrome / Central retinal vein occlusion Central retinal artery occlusion Branch retinal artery occlusion Retinopathy diabetic hypertensive Purtscher's of prematurity Bietti's crystalline dystrophy Coats' disease Sickle cell Macular degeneration Retinitis pigmentosa Retinal haemorrhage Central serous retinopathy Macular edema Epiretinal membrane (Macular pucker) Vitelliform macular dystrophy Leber's congenital amaurosis Birdshot chorioretinopathy Other Glaucoma / Ocular hypertension / Primary juvenile glaucoma Floater Leber's hereditary optic neuropathy Red eye Globe rupture Keratomycosis Phthisis bulbi Persistent fetal vasculature / Persistent hyperplastic primary vitreous Persistent tunica vasculosa lentis Familial exudative vitreoretinopathy Pathways Optic nerve Optic disc Optic neuritis optic papillitis Papilledema Foster Kennedy syndrome Optic atrophy Optic disc drusen Optic neuropathy Ischemic anterior (AION) posterior (PION) Kjer's Leber's hereditary Toxic and nutritional Strabismus Extraocular muscles Binocular vision Accommodation Paralytic strabismus Ophthalmoparesis Chronic progressive external ophthalmoplegia Kearns–Sayre syndrome palsies Oculomotor (III) Fourth-nerve (IV) Sixth-nerve (VI) Other strabismus Esotropia / Exotropia Hypertropia Heterophoria Esophoria Exophoria Cyclotropia Brown's syndrome Duane syndrome Other binocular Conjugate gaze palsy Convergence insufficiency Internuclear ophthalmoplegia One and a half syndrome Refraction Refractive error Hyperopia Myopia Astigmatism Anisometropia / Aniseikonia Presbyopia Vision disorders Blindness Amblyopia Leber's congenital amaurosis Diplopia Scotoma Color blindness Achromatopsia Dichromacy Monochromacy Nyctalopia Oguchi disease Blindness / Vision loss / Visual impairment Anopsia Hemianopsia binasal bitemporal homonymous Quadrantanopia subjective Asthenopia Hemeralopia Photophobia Scintillating scotoma Pupil Anisocoria Argyll Robertson pupil Marcus Gunn pupil Adie syndrome Miosis Mydriasis Cycloplegia Parinaud's syndrome Other Nystagmus Childhood blindness Infections Trachoma Onchocerciasis