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Dry Eyes
Mayo_clinic
Common causes of decreased tear production include: Aging Certain medical conditions including Sjogren's syndrome, allergic eye disease, rheumatoid arthritis, lupus, scleroderma, graft vs. host disease, sarcoidosis, thyroid disorders or vitamin A deficiency Certain medicines, including antihistamines, decongestants, hormone replacement therapy, antidepressants, and medicines for high blood pressure, acne, birth control and Parkinson's disease Corneal nerve desensitivity caused by contact lens use, nerve damage or laser eye surgery, though symptoms of dry eyes related to this procedure are usually temporary Increased tear evaporation The oil film produced by small glands on the edge of your eyelids (meibomian glands) might become clogged.TNF, NLRP3, IFNG, MMP9, TRPM8, IL17A, BPIFA2, TRPV1, CFTR, THBS1, MUC5AC, IL6, PAX6, HMGB1, CRP, EGF, TMSB4X, DNASE1, MUC1, MUC16, CA6, TAC1, IL1A, IL1B, NLRP6, SYMPK, VAMP8, SQSTM1, NSD2, RGN, MAPKAPK2, SPHK1, ACAT1, VDR, CRISP2, TLR4, TIMP1, TGM2, TGM1, TGFB3, TGFB2, PPP1R11, ELOVL4, STAT3, ST2, TRIM21, SPRR2A, ADIPOQ, NFAT5, ATG5, CREBZF, KIR2DS2, PRSS55, BHLHA15, TMTC3, RMDN2, PHETA1, LEAP2, IL33, SPZ1, TLR10, MAP1LC3B, BRCC3, ELOVL1, NOD2, HAMP, SCRN1, PBK, SYBU, RMDN3, TLR8, MZB1, RMDN1, CD207, HPGDS, CHIA, AATF, SPDEF, SOD1, NOD1, PRG4, SPRR1B, RPS6KA2, SOAT1, CSF2, HSP90AA1, HLA-DRB1, HLA-DRA, HLA-C, HCFC1, GSTP1, NR3C1, GPT, GOT2, EGFR, ATN1, DEFB4A, ACE, CTSS, CSF1R, SFTPD, CP, CCR7, CLU, CES1, CD47, CASP8, SERPING1, BDNF, BCL2, AR, AQP5, AIRE, ALB, JAG1, HTN1, ICAM1, IGF1, IGFBP3, CCL21, CCL19, CCL3, CCL2, RPS6KA3, ADCYAP1, RPS6KA1, PTGS2, PTGDS, PPARG, PPARA, POMC, CNTN3, P2RY2, OSM, MYD88, MTHFR, MPI, LGALS3, LCAT, KIR3DL2, KIR2DS1, ITGB2, ITGAM, ITGAL, IL18, IL13, IL10, IL5, DEFB4B
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Erectile Dysfunction
Mayo_clinic
Common causes include: Heart disease Clogged blood vessels (atherosclerosis) High cholesterol High blood pressure Diabetes Obesity Metabolic syndrome — a condition involving increased blood pressure, high insulin levels, body fat around the waist and high cholesterol Parkinson's disease Multiple sclerosis Certain prescription medications Tobacco use Peyronie's disease — development of scar tissue inside the penis Alcoholism and other forms of substance abuse Sleep disorders Treatments for prostate cancer or enlarged prostate Surgeries or injuries that affect the pelvic area or spinal cord Low testosterone Psychological causes of erectile dysfunction The brain plays a key role in triggering the series of physical events that cause an erection, starting with feelings of sexual excitement.NOS3, EDN1, BCL2, EDNRA, BCL2L1, VEGFA, SHBG, PRL, GRIN3A, PDE5A, VIP, NOS1, TNF, NOS2, IL6, GJA1, AKT1, AGT, CASP3, DYNLL1, GRK2, TGFB1, IGFBP3, BAD, BAX, P2RY2, CFL1, P2RY1, SIRT1, CCND2, HDAC3, PRKG1, KDR, FABP4, MCAM, AGER, CCND1, CNR1, FSHR, LMNB1, SUFU, TTC7A, ACOXL, CHD7, WDR11, KISS1, ANOS1, IRF8, GRAMD1B, HFE, HEXB, MATN2, NSMF, MEN1, SLC40A1, TTR, FGF17, TFR2, TACR3, TAC3, CACNA1G, SMARCB1, AIP, ATXN8OS, HS6ST1, PTGFRN, SP140, PDGFB, GUCY1A1, SACS, NF2, COQ2, HAMP, IRF4, ACE, FMR1, HJV, ABCD1, DUSP6, PROKR2, CDH13, SLC5A12, FGF8, FGFR1, GPR101, KISS1R, DRAIC, MIR4435-2HG, BMP2, SPRY4, ATXN8, CDH23, PROK2, GNRH1, GNRHR, CRP, ARG2, IGF1, GNB3, NGF, DECR1, BDNF, ALDH7A1, TLR4, ROCK2, ROCK1, SHH, CXCL12, TWIST2, AR, ADIPOQ, GPT, NECTIN1, MIAT, NFE2L2, MYOCD, ADRB3, MTHFR, TERT, FGF2, ALB, PTK2B, LOX, MBTPS1, TBPL1, PEA15, PCSK9, S1PR2, MIR155, MIR328, MIR146A, MIR205, MSC, MIR141, SELENBP1, CES2, CLOCK, MIR200A, PLA2G15, WASF2, ABCC4, TRPM8, PNPLA2, TP63, ACSS2, MEG3, DDIT4, CCHCR1, COA8, MCHR2, NT5C1A, SCLY, EBPL, MYLIP, ACCS, NUS1, DKK2, DKK3, SMR3A, PART1, OPRPN, DDAH1, DDAH2, NT5C2, MLXIP, CIT, MARCHF8, ESM1, IL27, NUS1P3, ACHE, POMC, VWF, MSTN, EGF, ELK3, ENG, ENO2, EPO, FLNA, FSHMD1A, GABPA, GH1, VHL, CXCR3, GUCY1B1, HMGCS2, IL7R, ILK, KCNMA1, KLK1, KRT7, DRD4, DRD2, CYP19A1, COMP, ADRA1A, AHSG, ALCAM, AMBP, ANGPT1, ANGPT2, KLK3, ARG1, ATM, BGLAP, VPS51, CAMP, CASP1, CD37, CD40, CDH5, CFTR, LBP, LEP, LIMK1, MAPK8, PTAFR, PTX3, RAC1, REG1A, ROS1, S100A1, S100A8, SDC1, SIM1, SLC2A1, SLC5A2, SOAT1, SRC, TAL1, THPO, TNNI3, TYRP1, PSMB9, PON1, LIMK2, ACTB, LPL, MBP, COX2, MYD88, NEUROD1, NPR1, OCA2, OXTR, PAEP, PCYT1A, PDE3A, SERPINF1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PITX3, CERNA3
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Canavan Disease
Gene_reviews
Disorders to Consider in the Differential Diagnosis of Canavan Disease View in own window Disorder Gene(s) MOI Clinical Features of This Disorder Overlapping w/Canavan disease Distinguishing from Canavan disease Alexander disease GFAP AD Neurodegenerative disorder of infancy Normal or large head Marked frontal predominance of white matter changes Rostrocaudal progression of myelin loss on serial imaging studies Tay-Sachs disease HEXA AR Neurodegenerative disorder of infancy Normal or large head Increased startle response Cherry-red spot of the macula of the retina Metachromatic leukodystrophy ARSA AR Neurodegenerative disorder of infancy Normal or large head Late-infantile onset (age <30 mos) after a period of apparently normal development Glutaric acidemia type 1 GCDH AR Neurodegenerative disorder of infancy Normal or large head Progressive movement disorder Leigh syndrome (see also Mitochondrial Disorders Overview) mtDNA mt AR Spongy degeneration of the brain Decompensation (often w/elevated lactate levels in blood &/or CSF) during an intercurrent illness is typically associated w/psychomotor retardation or regression.
- Muscular Dystrophy, Congenital Merosin-Deficient, 1a Omim
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Grin1-Related Neurodevelopmental Disorder
Gene_reviews
Differential Diagnosis Because the phenotypic features associated with GRIN1 -related neurodevelopmental disorder ( GRIN1 -NDD) are not sufficient to diagnose this condition, all disorders with the following features should be considered in the differential diagnosis: Intellectual disability (ID) without other distinctive findings; to date more than 180 such disorders have been identified (see OMIM Phenotypic Series: Autosomal dominant ID, Autosomal recessive ID, Nonsyndromic X-linked ID, and Syndromic X-linked ID). Early-onset epileptic encephalopathy (EIEE); to date, more than 70 disorders with EIEE have been identified (see EIEE OMIM Phenotypic Series).
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16p11.2 Recurrent Microdeletion
Gene_reviews
Heterozygous loss-of-function PRRT2 pathogenic variants (which cause paroxysmal kinesigenic dyskinesia; see following) also cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndrome [Heron et al 2012], both of which have been reported in a number of individuals with the 16p11.2 recurrent microdeletion.
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Htra1 Disorder
Gene_reviews
Nomenclature Other names for HTRA1 disorder include the following: CARASIL, for those who have biallelic HTRA1 pathogenic variants Familial young adult-onset arteriosclerotic leukoencephalopathy with alopecia and lumbago without arterial hypertension Nemoto disease Maeda syndrome CADASIL2 ( c erebral a rteriopathy, a utosomal d ominant, with s ubcortical i nfarcts and l eukoencephalopathy, type 2; OMIM 616779) Prevalence HTRA1 disorder has been reported in individuals from Asia, Europe, and North America.
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Duarte Variant Galactosemia
Gene_reviews
The differential diagnosis of a positive NBS for galactosemia is: Classic galactosemia and clinical variant galactosemia Duarte variant galactosemia GALE (epimerase) deficiency galactosemia GALK (galactokinase) deficiency (OMIM 230200) GALM deficiency galactosemia (OMIM 618881) Compromised galactose utilization not caused by a Leloir enzyme deficiency (e.g., Fanconi-Bickel syndrome [OMIM 227810] or portosystemic shunt [Bernard et al 2012]).
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Pulmonary Hypertension, Primary, 1
Omim
Pediatric-onset pulmonary hypertension may be seen in association with ischiocoxopodopatellar syndrome (ICPPS; 147891). The skeletal manifestations of ICPPS are highly variable and may not be detected in children.
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Galactosemia
Omim
Heterogeneity Clinical Heterogeneity With the several mutations that have been identified at the GALT locus, the tendency for clinical complications to develop varies from apparent clinical normality in the relatively common Duarte type to perhaps mild symptoms in the S135L variant and to the severe galactosemia syndrome in the 'classic,' Indiana, and Rennes variants (Hammersen et al., 1975).
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Angioedema, Hereditary, Type I
Omim
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Search Hereditary Angioedema case abstracts
Perricone et al. (1992) concluded that polycystic ovaries (PCO syndrome; 184700) or multifollicular ovaries occur with unusually high frequency in women with HANE.
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Hiv/aids In The Philippines
Wikipedia
. ^ "Duterte signs law strengthening HIV, AIDS health services" . v t e HIV/AIDS in Asia Sovereign states Afghanistan Armenia Azerbaijan Bahrain Bangladesh Bhutan Brunei Cambodia China Cyprus East Timor (Timor-Leste) Egypt Georgia India Indonesia Iran Iraq Israel Japan Jordan Kazakhstan North Korea South Korea Kuwait Kyrgyzstan Laos Lebanon Malaysia Maldives Mongolia Myanmar Nepal Oman Pakistan Philippines Qatar Russia Saudi Arabia Singapore Sri Lanka Syria Tajikistan Thailand Turkey Turkmenistan United Arab Emirates Uzbekistan Vietnam Yemen States with limited recognition Abkhazia Artsakh Northern Cyprus Palestine South Ossetia Taiwan Dependencies and other territories British Indian Ocean Territory Christmas Island Cocos (Keeling) Islands Hong Kong Macau Book Category Asia portal v t e HIV / AIDS topics HIV/AIDS HIV HIV Lentivirus structure and genome subtypes CDC classification disease progression rates HIV/AIDS diagnosis management pathophysiology prevention research vaccination PrEP WHO disease staging system for HIV infection and disease Children Teens / Adults Countries by AIDS prevalence rate Conditions Signs and symptoms AIDS-defining clinical condition Diffuse infiltrative lymphocytosis syndrome Lipodystrophy Nephropathy Neurocognitive disorders Pruritus Superinfection Tuberculosis co-infection HIV Drug Resistance Database Innate resistance to HIV Serostatus HIV-positive people Nutrition Pregnancy History History Epidemiology Multiple sex partners Timeline AIDS Museum Timothy Ray Brown Women and HIV/AIDS Social AIDS orphan Catholic Church and HIV/AIDS Circumcision and HIV Criminal transmission Discrimination against people Economic impact Cost of treatment HIV-affected community HIV/AIDS activism HIV/AIDS denialism Red ribbon Safe sex Sex education List of HIV-positive people People With AIDS Self-Empowerment Movement HIV/AIDS in the porn industry Culture Discredited HIV/AIDS origins theories International AIDS Conference International AIDS Society Joint United Nations Programme on HIV/AIDS (UNAIDS) Media portrayal of HIV/AIDS Misconceptions about HIV/AIDS President's Emergency Plan for AIDS Relief (PEPFAR) The SING Campaign Solidays Treatment Action Campaign World AIDS Day YAA/Youthforce "Free Me" Larry Kramer Gay Men's Health Crisis ACT UP Silence=Death Project HIV/AIDS pandemic by region / country Africa Angola Benin Botswana Democratic Republic of the Congo Egypt Eswatini Ethiopia Ghana Guinea Côte d'Ivoire (Ivory Coast) Kenya Lesotho Madagascar Malawi Mali Mozambique Namibia Niger Nigeria Rwanda Senegal Tanzania South Africa Uganda Zambia Zimbabwe North America Canada Mexico El Salvador Guatemala Honduras Nicaragua United States New York City Caribbean Haiti Jamaica Dominican Republic South America Bolivia Brazil Colombia Guyana Peru Asia Afghanistan Armenia Azerbaijan Bahrain Bangladesh Bhutan Cambodia China (PRC) ( Yunnan ) East Timor India Indonesia Iran Iraq Japan Jordan North Korea Laos Malaysia Myanmar (Burma) Nepal Pakistan Philippines Saudi Arabia Sri Lanka Taiwan (ROC) Thailand United Arab Emirates Turkey Vietnam Europe United Kingdom Russia Ukraine Oceania Australia New Zealand Papua New Guinea List of countries by HIV/AIDS adult prevalence rate List of HIV/AIDS cases and deaths registered by region
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Alcohol Myopia
Wikipedia
Sulfonic acids : Acamprosate Religion and alcohol Christian views on alcohol alcohol in the Bible Islam and alcohol History Bratt System Related Index of alcohol-related articles Austrian syndrome Ban on caffeinated alcoholic beverages Brief intervention Gateway drug effect Last call Mood disorder Non-alcoholic fatty liver disease Self-medication Spins Sober companion Sober living houses Sobering center Town drunk Category
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Diabetes In Cats
Wikipedia
. ^ Hayden, MR (September 2002). "Islet amyloid, metabolic syndrome, and the natural progressive history of type 2 diabetes mellitus".
- Asbestos-Related Diseases Wikipedia
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Dependent Personality Disorder
Wikipedia
Richards, Henry Jay (1993). Therapy of the Substance Abuse Syndromes . New York: Jason Aronson. ISBN 978-0-87668-539-6 .
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Abortion In Hawaii
Wikipedia
Under Donald Trump, these dollars have been cut in Hawaii, leaving poor and rural women particularly vulnerable when it comes to ability to access prenatal care . [11] History [ edit ] After Hawaii legalized abortion in 1970, the number of live births of children with Down syndrome decreased. [12] Women in rural Hawaii faced huge problems getting access to abortion services in 2017. [11] Women seeking abortions in 2017 often had to travel great distances, often paying more than $300 and take one or more days off and book accommodation, to get an abortion.
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Codependency
Wikipedia
Codependency support: general at Curlie Codependency support: co-alcoholic at Curlie Codependency support: borderline personality disorder at Curlie v t e Borderline personality disorder General Dimensional models of personality disorders Impulse control disorders Trauma model of mental disorders Misdiagnosis of borderline personality disorder Symptoms and behaviors Dissociation Eating disorders Emotional dysregulation Feelings of emptiness Hypersexuality Idealization and devaluation Impulsivity Mood swings Projection Self-harm Splitting Suicidal ideation Management Dialectical behavior therapy Dynamic deconstructive psychotherapy McLean Hospital Mentalization-based treatment Schema therapy Social psychiatry Transference focused psychotherapy Family challenges BPDFamily (support group) Codependency Complex PTSD Emotional blackmail Family estrangement Personal boundaries v t e Narcissism Types Collective Egomania Flying monkeys Healthy Malignant Narcissistic personality disorder Spiritual Workplace Characteristics Betrayal Boasting Egocentrism Egotism Empathy (lack of) Envy Entitlement (exaggerated sense of) Fantasy Grandiosity Hubris Magical thinking Manipulative Narcissistic abuse Narcissistic elation Narcissistic rage and narcissistic injury Narcissistic mortification Narcissistic supply Narcissistic withdrawal Perfectionism Self-esteem Self-righteousness Shamelessness Superficial charm Superiority complex True self and false self Vanity Defences Denial Idealization and devaluation Distortion Projection Splitting Cultural phenomena Control freak Don Juanism Dorian Gray syndrome My way or the highway Selfie Related articles Codependency Counterdependency Dark triad Ego ideal "Egomania" (film) Egotheism Empire-building God complex History of narcissism Messiah complex Micromanagement Narcissism of small differences Narcissistic leadership Narcissistic parent Narcissistic Personality Inventory Narcissus (mythology) On Narcissism Sam Vaknin Self-love Self-serving bias Spoiled child The Culture of Narcissism Workplace bullying
- Non-Communicable Disease Wikipedia
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Blast-Related Ocular Trauma
Wikipedia
Healing of these injuries occurs naturally by scarring of dorsal orbital fat to the sclera . [2] [3] If a clinically significant increase in intraocular pressure is detected with orbital compartment syndrome, the ophthalmologist may perform an emergency canthotomy on the lateral canthus.