• FindZebra
  • About
  • Contact
  • Help
  • Login
Advanced
  • Hyperuricemia Wikipedia
    Medications that have a similar effect include acetazolamide . [ medical citation needed ] Temperature [ edit ] Low temperature is a reported trigger of acute gout. [28] An example would be a day spent standing in cold water, followed by an attack of gout the next morning.
    XDH, HPRT1, ABCG2, SLC2A9, ALDH16A1, APLN, SLC5A8, JAK2, SLC22A2, SLC22A12, UMOD, STAT3, REN, HNF1B, PRPS1, MUC1, PPARG, G6PC, SARS2, VEGFA, CLDN16, PFKM, MYC, PHKG2, NFATC1, GNAS, SIPA1L3, PHKA2, SFMBT1, LRP2, TNFRSF11B, SEC61A1, IGF1R, HMBS, NFAT5, KCNQ1, HMGCL, HNF4A, LRIG1, SH2B1, EIF2AK3, ACAT1, SLC2A6, RREB1, SLC37A4, SLC25A26, WDR72, TNFRSF11A, DPEP1, UOX, BAZ1B, KCNQ1-AS1, ETV5, ALMS1, ALDOB, FBP1, TMEM171, BCAS1, NLRP3, IL6, IL1B, SLC22A6, TNF, GPT, MTHFR, APOE, CRP, ADRB3, ALB, RAPGEF5, SLC5A2, KCNK3, IL18, CXCL8, HLA-B, SIRT1, P2RX7, SLC22A8, PERCC1, MEFV, LCN2, FABP2, APOA1, DECR1, DBP, GCKR, CASP8, GH1, CYBA, COL1A1, ZNF365, WNT3A, FUZ, SELENBP1, ZPBP2, PLA2G7, SLC28A2, BPIFA2, OIT3, IFNL3, MIR143, UCP2, P2RX5-TAX1BP3, P2RX6, ADIPOQ, WNK1, GORASP1, RIPK3, SLC17A3, GPATCH8, MPRIP, KLF2, HAVCR1, ABCC4, RIDA, SLC17A4, SLC23A1, ADIPOR1, CCHCR1, SHLD2, SLC47A1, CDC42BPG, SLC22A11, P2RX2, TYMS, ABCA4, THBD, GLI2, FBL, ETFA, EZH2, FOXO3, MTOR, GJA4, GNB3, ATN1, HAS2, HBG1, HBG2, HFE, HNF4G, HSPA9, EDN1, CST3, TCTA, B2M, ACTA2, ADH1B, AFP, ALDH2, APOC3, AR, CAPN1, CSH2, CASP3, CAT, ERCC8, CLTC, COMP, CSH1, HTR2A, IL10, KHK, RRBP1, PRPSAP1, PRPSAP2, PSPH, RARRES2, REG1A, RELA, SAA1, MAOA, CCL2, CCL5, SHBG, SLC4A1, STXBP3, SYT1, PSPN, MAPK3, PRKG2, POU2F2, PON1, SERPINA5, PC, P2RY2, P2RY1, P2RX5, P2RX4, P2RX3, P2RX1, PNP, MSMB, MMP3, NR3C2, PPARA
  • Stomatitis Wikipedia
    . ^ "Balsam of Peru contact allergy" . Dermnetnz.org. December 28, 2013 . Retrieved March 5, 2014 . ^ James, William D.; Berger, Timothy G.; et al. (2006).
    XRCC1, NBN, CSF3, IFNA2, FGF7, TNF, ALB, EGF, MTHFR, ABCB1, DPYD, EPO, XRCC3, TFF3, SCT, TGFB1, RRM1, TNFRSF1A, TYMS, RNR1, AGT, XRCC5, RAD51, TBC1D9, SIRT1, FBXO3, GHRL, GRHL3, DMRTA1, SPNS1, MIR200C, MIR1206, MIR2053, LGR5, NARS1, PPARG, PECAM1, APEH, CCND1, ABCC2, CSF2, CYP2B6, ESR1, FGF2, MTOR, XRCC6, GSK3B, H2AX, HMGB1, IKBKB, IL1A, IL1B, CXCL8, CXCR2, IL17A, SMAD7, MTX1, CNOT4, PERCC1
  • Latent Autoimmune Diabetes In Adults Wikipedia
    Risk factors [ edit ] There is limited research on LADA and its etiology. [21] [4] As with both T1D and T2D, the risk of LADA depends on both genetic and environmental factors. [21] [15] Genetic risk factors for LADA are similar to T1D, i.e. is affected by the HLA complex, but also genetic variants associated with T2D have been identified in LADA. [21] LADA has several lifestyle risk factors in common with T2D, such as obesity, physical inactivity, smoking and consumption of sweetened beverages, all of which are linked to insulin resistance. [21] Obesity has been shown to increase the risk of LADA in several studies, and one study showed that the risk was particularly high in combination with having diabetes in the family. [21] [22] [23] Physical activity also affects the risk of LADA, with less physical activity increasing the risk. [21] A Swedish study showed that low birth weight, in addition to increasing the risk of T2D, increases the risk of LADA. [24] Although smoking has been shown to increase the risk of T2D while coffee consumption has been shown to reduce the risk of T2D, the results regarding these products and LADA are unclear. [21] However, results from two studies based on the same population seem to indicate that coffee consumption increases the risk of LADA. [25] [26] Other foods that have been shown to increase the risk of LADA are sweetened beverages and processed red meat [27] [28] [29] while consumption of fatty fish has been shown to have a protective effect. [30] Management [ edit ] Main article: Diabetes management Diabetes is a chronic disease, i.e. it cannot be cured, but symptoms and complications can be minimized with proper treatment.
    PTPN22, INS, ATXN2, INS-IGF2, BACH2, SH2B3, CTLA4, DPP4, GAD2, TCF7L2, GAD1, LINC01193, SOX13, MICA, HLA-DQB1, HLA-DOA, HLA-DRB1, GCG, CCR2, CSN2, SUMO4, DSPP, SUV39H2, FTO, FABP5, SOST, FOXP3, GPT, KDM4C, HNF4A, TSPAN7, HLA-DQA1, PDE4B, LAD1, CCR5, IL18, IL6, IFNG, CD38
  • Far-Sightedness Wikipedia
    October 2010. Archived from the original on 28 July 2016 . Retrieved 30 July 2016 . ^ "Complications of long-sightedness" .
    MFRP, NOG, CRB1, RPGR, POMT2, NPAP1, SIN3A, B3GAT3, PGAP2, ANKRD11, MKRN3-AS1, IFT52, PIGT, MAGEL2, P4HTM, CNGB3, RBFOX1, SLC25A24, ADNP, SETD5, SYNE1, PACS2, POGZ, IQSEC2, EMC1, ATF6, PUF60, MAN1B1, POLR3A, KERA, SRCAP, YME1L1, CLDN16, CTCF, PHIP, PIGV, RAD50, LCA5, PIGY, SHANK3, PGAP3, DMBX1, DNAJC21, PWAR1, FLCN, TBC1D23, CHAMP1, KANSL1, PIGW, SNORD115-1, BLOC1S3, PWRN1, PIGO, KIAA1109, FBXO11, TCTN2, EHMT1, BCL11B, NMNAT1, NSD1, SLC39A8, FAM111A, TRPV4, WDR19, KIDINS220, GATAD2B, CCDC47, ERMARD, MBD5, ZMPSTE24, SNORD116-1, NDN, PDE6C, PCNT, NFIX, NEK1, PQBP1, MRE11, MITF, MIPEP, FOXL2, MARK3, MAG, SMAD4, LMNA, LAMA2, KIF11, IPW, GRID1, GNAT2, FGF14, FGD1, FKTN, ERCC6, EPRS1, CTNNB1, COL3A1, CNGA3, ERCC8, CHD3, CACNA1A, CHMP1A, PDE6H, BEST1, APOE, PIGL, CHST3, EIF2AK3, RAB11B, HERC2, CACNA1G, EED, PPM1D, KDM5C, USP9X, ZNF148, PDGFRB, MKRN3, SLC35A2, TYR, SON, SNRPN, SLC6A8, RS1, ATP6V1A, DPF2, ATP6AP1, PTPN11, PEX1, HGF, PRSS56, RAB8A, CACNA1F, MYRF, APLP2, GUCY2D, CABP4, RARA, RPE, SOX2, IFT140, AAVS1
    • Farsightedness Mayo_clinic
      Overview Farsightedness (hyperopia) is a common vision condition in which you can see distant objects clearly, but objects nearby may be blurry. The degree of your farsightedness influences your focusing ability. People with severe farsightedness may be able to clearly see only objects a great distance away, while those with mild farsightedness may be able to clearly see objects that are closer. Farsightedness usually is present at birth and tends to run in families. You can easily correct this condition with eyeglasses or contact lenses. Another treatment option is surgery. Symptoms Farsightedness may mean: Nearby objects may appear blurry You need to squint to see clearly You have eyestrain, including burning eyes, and aching in or around the eyes You have general eye discomfort or a headache after doing close tasks, such as reading, writing, computer work or drawing, for a time When to see a doctor If your degree of farsightedness is pronounced enough that you can't perform a task as well as you wish, or if your quality of vision detracts from your enjoyment of activities, see an eye doctor.
  • Cryptococcosis Wikipedia
    Soil, fowl manure, and pigeon droppings are among the sources of infection. [28] [29] References [ edit ] ^ "Cryptococcosis" .
    CHIA, TNF, IFNG, DDX56, CYP51A1, SMUG1, LYPLA1, LAMC2, IL18, CSF2, SOD1, TAP1, FKBP1AP4, FKBP1AP3, FKBP1AP2, FKBP1AP1, FKBP1A, FBP1, IL17A, IL6, CLEC4D, FAS, CLEC6A, BRD4, GNLY, SORBS1, PRPF8, EBNA1BP2, VPS45, EPB41L3, MLIP, CAP1, ATP6V0A2, DNPEP, SEC1P, GORASP2, VCX, VPS41, GLRX3, SLC9A6, SLC39A1, YAP1, LINC01672, KLHL41, LANCL1, TCIRG1, AK6, RABEPK, HDAC9, ATG5, S1PR2, AURKB, HACD1, ARHGEF2, ARTN, LGALS7B, ATP6V0A4, SLC39A2, UGGT1, MIOX, PLB1, SLC9B1, SRXN1, IL31RA, NLRP3, CLEC7A, UBASH3B, GORASP1, IPPK, ATG9A, SCD5, MINDY4, IL33, SLC30A10, UGT1A3, UGT1A1, UGT1A4, SHOC1, ZFP1, UGT1A9, UGT1A5, TP63, UGT1A6, NCR3, UGT1A7, UGT1A8, ARMH1, UGT1A10, MBTPS2, MBL3P, PABPC4, ACTB, SLC30A1, CTAA1, EPHA2, ERN1, FCGR2A, FCGR2B, FCGR3A, FCGR3B, HK2, HSPA4, HSP90AA1, HTN3, ICAM1, IGHG3, IL4, IL5, IL9, DNAH8, CPS1, ITGB2, CP, ANXA2, ANXA6, AQP1, ARG1, ATP6V0A1, CASP1, CD2, CD44, CDK8, CGA, RCC1, CHIT1, CLU, CCR5, SLC31A2, ITGAL, RPSA, CNBP, PTPRC, RPS4X, CCL5, SLC6A1, SOAT1, SP1, SRM, STAT1, TGFBR1, AGRP, TXN, SLC35A2, UGT1A, WAS, XPNPEP1, XPO1, PTX3, PSMD7, LGALS3, MAPK1, LGALS7, LNPEP, MBL2, MID1, MMP9, MPI, NFKB1, NM, PCK1, SERPINB6, PITX2, PPARG, PRKAA1, PRKAA2, PRKAB1, H3P28
    • Cryptococcosis Orphanet
      A cosmopolitan fungal infection due to Cryptococcus neoformans . Epidemiology Annual incidence has been estimated at between 1/5,000 and 1/50,000 depending on the geographic region. Immunodeficient patients are the main target. Clinical description Primary pulmonary cryptococcosis is usually asymptomatic, but disseminates throughout the organism, particularly to the central nervous system causing subacute meningoencephalitis. Mucocutaneous infection is frequent. Etiology C. neoformans is an encapsulated yeast that reproduces by budding. It is abundant in the ground, in fruit, milk, and pigeon droppings. Infection is acquired via the respiratory or digestive route, rarely through the skin, and disseminates in the organism by blood or the lymphatic system. Interhuman transmission does not occur. Diagnostic methods Diagnosis is made after detection of encapsulated yeast in cerebrospinal fluid or other affected organs, or in cultures.
  • Mitochondrial Dna Depletion Syndrome 1 (Mngie Type) Omim
    Two had sensorineural deafness. Death occurred between ages 28 and 39 years, suggesting that decreased life span is associated with this disorder.
    TYMP, RRM2B, POLG, SCO2
    • Mitochondrial Dna Depletion Syndrome 4b (Mngie Type) Omim
      A number sign (#) is used with this entry because of evidence that mitochondrial DNA depletion syndrome-4B (MTDPS4B), which manifests as a neurogastrointestinal encephalopathy (MNGIE), is caused by compound heterozygous mutation in the POLG gene (174763) on chromosome 15q26. See also MTDPS1 (603041) for a more common form of MNGIE caused by recessive mutation in the thymidine phosphorylase gene (TYMP; 131222). Description Mitochondrial DNA depletion syndrome-4B is an autosomal recessive progressive multisystem disorder clinically characterized by chronic gastrointestinal dysmotility and pseudoobstruction, cachexia, progressive external ophthalmoplegia (PEO), axonal sensory ataxic neuropathy, and muscle weakness (van Goethem et al., 2003). For a discussion of genetic heterogeneity of autosomal recessive mtDNA depletion syndromes, see MTDPS1 (603041). Clinical Features Vissing et al. (2002) reported 2 sisters who presented at age 15 years with unsteady gait and gastrointestinal malabsorption.
    • Mitochondrial Neurogastrointestinal Encephalopathy Disease Gene_reviews
      Summary Clinical characteristics. Mitochondrial neurogastrointestinal encephalopathy (MNGIE) disease is characterized by progressive gastrointestinal dysmotility (manifesting as early satiety, nausea, dysphagia, gastroesophageal reflux, postprandial emesis, episodic abdominal pain and/or distention, and diarrhea); cachexia; ptosis/ophthalmoplegia or ophthalmoparesis; leukoencephalopathy; and demyelinating peripheral neuropathy (manifesting as paresthesias (tingling, numbness, and pain) and symmetric and distal weakness more prominently affecting the lower extremities). The order in which manifestations appear is unpredictable. Onset is usually between the first and fifth decades; in about 60% of individuals, symptoms begin before age 20 years. Diagnosis/testing. The clinical diagnosis of MNGIE disease is based on the presence of severe gastrointestinal dysmotility, cachexia, ptosis, external ophthalmoplegia, sensorimotor neuropathy, asymptomatic leukoencephalopathy as observed on brain MRI, and family history consistent with autosomal recessive inheritance. The diagnosis of MNGIE disease can be established in a proband by detection of one of the following: (1) biallelic pathogenic variants in TYMP (formerly known as ECGF1 ); (2) markedly reduced levels of thymidine phosphorylase enzyme activity; or (3) elevated plasma concentrations of thymidine and deoxyuridine. Management. Treatment of manifestations: Management is primarily supportive and includes attention to swallowing difficulties and airway protection; dromperidone for nausea and vomiting; gastrostomy, and parenteral feeding for nutritional support; antibiotics for intestinal bacterial overgrowth; amitriptyline, nortriptyline, and gabapentin for neuropathic symptoms; specialized schooling arrangements; and physical and occupational therapy.
    • Mitochondrial Dna Depletion Syndrome 8a (Encephalomyopathic Type With Renal Tubulopathy) Omim
      A number sign (#) is used with this entry because mitochondrial DNA depletion syndromes 8A (MTDPS8A) and 8B (MTDPS8B) are caused by homozygous or compound heterozygous mutation in the RRM2B gene (604712) on chromosome 8q22. See also PEOA5 (613077), an allelic disorder caused by heterozygous mutations in the RRM2B gene. Description Mitochondrial DNA depletion syndrome-8A is a severe autosomal recessive disorder characterized by neonatal hypotonia, lactic acidosis, and neurologic deterioration. Renal tubular involvement may also occur (Bourdon et al., 2007). Mitochondrial DNA depletion syndrome-8B is characterized by ophthalmoplegia, ptosis, gastrointestinal dysmotility, cachexia, peripheral neuropathy, and brain MRI changes, known as the MNGIE phenotype (Shaibani et al., 2009). For a discussion of genetic heterogeneity of mtDNA depletion syndromes, see MTDPS1 (603041).
    • Mitochondrial Neurogastrointestinal Encephalopathy Syndrome Wikipedia
      Mitochondrial neurogastrointestinal encephalopathy syndrome Other names MNGIE syndrome Structure of thymidine phosphorylase enzyme, the main gene product of the TYMP gene. Mutations in the TYMP gene result in the loss of function of thymidine phosphorylase activity leading to the onset of MNGIE. [1] Mitochondrial neurogastrointestinal encephalopathy syndrome ( MNGIE ) is a rare autosomal recessive mitochondrial disease. [2] It has been previously referred to as polyneuropathy , ophthalmoplegia , leukoencephalopathy , and POLIP syndrome. [3] The disease presents in childhood, but often goes unnoticed for decades. [2] [4] [5] Unlike typical mitochondrial diseases caused by mitochondrial DNA (mtDNA) mutations, MNGIE is caused by mutations in the TYMP gene, which encodes the enzyme thymidine phosphorylase . [2] [5] Mutations in this gene result in impaired mitochondrial function, leading to intestinal symptoms as well as neuro-ophthalmologic abnormalities. [2] [4] A secondary form of MNGIE, called MNGIE without leukoencephalopathy , can be caused by mutations in the POLG gene. [3] Contents 1 Signs and symptoms 2 Genetics 3 Diagnosis 4 Management 5 References 6 External links Signs and symptoms [ edit ] Like other mitochrondrial diseases, MNGIE is a multisystem disorder . [6] MNGIE primarily affects the gastrointestinal and neurological systems. Gastrointestinal symptoms may include gastrointestinal dysmotility, due to inefficient peristalsis , which may result in pseudo-obstruction and cause malabsorption of nutrients. [2] [5] Additionally, gastrointestinal symptoms such as borborygmi , early satiety, diarrhea, constipation, gastroparesis , nausea, vomiting, weight loss, and diverticulitis may be present in MNGIE patients. [2] Neurological symptoms may include diffuse leukoencephalopathy , peripheral neuropathy , and myopathy . [2] Ocular symptoms may include retinal degeneration, ophthalmoplegia , and ptosis . [2] [5] Those with MNGIE are often thin and experience continuous weight loss. The characteristic thinness of MNGIE patients is caused by multiple factors including inadequate caloric intake due to gastrointestinal symptoms and discomfort, malabsorption of food from bacterial overgrowth due to decreased motility, as well as an increased metabolic demand due to inefficient production of ATP by the mitochondria. [ citation needed ] Genetics [ edit ] A variety of mutations in the TYMP gene have been discovered that lead to the onset of mitochondrial neurogastrointestinal encephalopathy syndrome. [2] The TYMP gene is a nuclear gene, however, mutations in the TYMP gene affect mitochrondrial DNA and function. [2] Mutations in this gene result in a loss of thymidine phosphorylase activity. [2] Thymidine phosphorylase is the enzymatic product of the TYMP gene and is responsible for breaking down thymidine nucleosides into thymine and 2-deoxyribose 1-phosphate. [2] Without normal thymidine phosphorylase activity, thymidine nucleosides begin to build up in cells. [2] High nucleoside levels are toxic to mitochondrial DNA and cause mutations that lead to dysfunction of the respiratory chain , and thus, inadequate energy production in the cells. [2] These mitochondrial effects are responsible for the symptomatology associated with the disease. [2] Diagnosis [ edit ] Diverticula While the disease manifests early in life in most cases, diagnosis of the disease is often quite delayed. [2] [4] [5] The symptoms that affected patients present vary, but the most common presenting symptoms are gastrointestinal issues such as nausea, vomiting, abdominal pain, and diarrhea, and neurologic or ocular symptoms such as hearing loss, weakness, and peripheral neuropathy. [4] These gastrointestinal symptoms cause patients with MNGIE to be very thin and experience persistent weight loss and this often leads to MNGIE being misdiagnosed as an eating disorder. [2] These symptoms without presentation of disordered eating and warped body image warrant further investigation into the possibility of MNGIE as a diagnosis. [2] Presentation of these symptoms and lack of disordered eating are not enough for a diagnosis. Radiologic studies showing hypoperistalsis, large atonic stomach, dilated duodenum, diverticula , and white matter changes are required to confirm the diagnosis. [4] Elevated blood and urine nucleoside levels are also indicative of MNGIE syndrome. [2] Abnormal nerve conduction as well as analysis of mitochondria from liver, intestines, muscle, and nerve tissue can also be used to support the diagnosis. [2] [4] Management [ edit ] A successful treatment for MNGIE has yet to be found, however, symptomatic relief can be achieved using pharmacotherapy and celiac plexus neurolysis. [4] Celiac plexus neurolysis involves interrupting neural transmission from various parts of the gastrointestinal tract.
    • Mitochondrial Neurogastrointestinal Encephalopathy Syndrome Gard
      Mitochondrial neurogastrointestinal encephalopathy (MNGIE) syndrome is a condition that mainly affects the digestive system and nervous system. Signs and symptoms most often begin by age 20 and worsen with time. Almost all people with MNGIE have gastrointestinal dysmotility, in which the muscles and nerves of the digestive system do not move food through the digestive tract efficiently and result in early satiety, nausea, dysphagia, gastroesophageal reflux, vomiting after eating (postprandial emesis), episodic abdominal pain and/or distention, and diarrhea . Affected people may also have cachexia, dropped eyelids or weakness of other muscles of the eyes, peripheral neuropathy (manifesting as tingling, numbness, and pain (paresthesias) symmetric weakness, that mainly affect the lower extremities) and hearing loss. Leukoencephalopathy, which is the deterioration of a type of brain tissue known as white matter, is a hallmark of MNGIE; however it does not usually cause symptoms in people with this disorder. MNGIE is caused by variations (mutations) in the TYMP gene, important for allowing adequate levels of thymidine in the mitochondria.
    • Mitochondrial Neurogastrointestinal Encephalomyopathy Orphanet
      Mitochondrial NeuroGastroIntestinal Encephalomyopathy (MNGIE) syndrome is characterized by the association of gastrointestinal dysmotility, peripheral neuropathy, chronic progressive external ophthalmoplegia and leukoencephalopathy. Epidemiology So far, just under 100 sporadic and familial cases have been reported. Clinical description The first clinical manifestations generally appear between the ages of 10 and 40 (most often before 20 years of age). The symptoms are progressive and the clinical picture is dominated by severe gastrointestinal disorders (cramping, vomiting, diarrhea, intestinal pseudo-obstruction, dysphagia and gastroparesis) due to abnormal bowel motility. Gastrointestinal disorders gradually progress to chronic pseudo-obstruction leading to cachexia.
  • Breast Cancer Wikipedia
    These symptoms are called non-specific symptoms because they could be manifestations of many other illnesses. [28] Rarely breast cancer can spread to exceedingly uncommon sites such as peripancreatic lymph nodes causing biliary obstruction leading to diagnostic difficulties. [29] Most symptoms of breast disorders, including most lumps, do not turn out to represent underlying breast cancer. ... Preventive Services Task Force and American College of Physicians recommends mammography every two years in women between the ages of 50 and 74, [11] [106] the Council of Europe recommends mammography between 50 and 69 with most programs using a 2-year frequency, [107] while the European Commission recommends mammography from 45 to 75 every 2 to 3 years, [108] and in Canada screening is recommended between the ages of 50 and 74 at a frequency of 2 to 3 years. [109] These task force reports point out that in addition to unnecessary surgery and anxiety, the risks of more frequent mammograms include a small but significant increase in breast cancer induced by radiation. [110] The Cochrane collaboration (2013) states that the best quality evidence neither demonstrates a reduction in cancer specific, nor a reduction in all cause mortality from screening mammography. [9] When less rigorous trials are added to the analysis there is a reduction in mortality due to breast cancer of 0.05% (a decrease of 1 in 2000 deaths from breast cancer over 10 years or a relative decrease of 15% from breast cancer). [9] Screening over 10 years results in a 30% increase in rates of over-diagnosis and over-treatment (3 to 14 per 1000) and more than half will have at least one falsely positive test. [9] [111] This has resulted in the view that it is not clear whether mammography screening does more good or harm. [9] Cochrane states that, due to recent improvements in breast cancer treatment, and the risks of false positives from breast cancer screening leading to unnecessary treatment, "it therefore no longer seems beneficial to attend for breast cancer screening" at any age. [112] Whether MRI as a screening method has greater harms or benefits when compared to standard mammography is not known. [113] [114] Prevention [ edit ] Lifestyle [ edit ] Women can reduce their risk of breast cancer by maintaining a healthy weight, reducing alcohol use, increasing physical activity, and breast-feeding. [115] These modifications might prevent 38% of breast cancers in the US, 42% in the UK, 28% in Brazil, and 20% in China. [115] The benefits with moderate exercise such as brisk walking are seen at all age groups including postmenopausal women. [115] [116] High levels of physical activity reduce the risk of breast cancer by about 14%. [117] Strategies that encourage regular physical activity and reduce obesity could also have other benefits, such as reduced risks of cardiovascular disease and diabetes. [32] The American Cancer Society and the American Society of Clinical Oncology advised in 2016 that people should eat a diet high in vegetables, fruits, whole grains, and legumes. [118] High intake of citrus fruit has been associated with a 10% reduction in the risk of breast cancer. [119] Marine omega-3 polyunsaturated fatty acids appear to reduce the risk. [120] High consumption of soy -based foods may reduce risk. [121] Pre-emptive surgery [ edit ] Removal of both breasts before any cancer has been diagnosed or any suspicious lump or other lesion has appeared (a procedure known as "prophylactic bilateral mastectomy " or "risk reducing mastectomy") may be considered in people with BRCA1 and BRCA2 mutations, which are associated with a substantially heightened risk for an eventual diagnosis of breast cancer. [122] [123] Evidence is not strong enough to support this procedure in anyone but those at the highest risk. [124] BRCA testing is recommended in those with a high family risk after genetic counseling. ... In the twelve world regions, the annual age-standardized incidence rates per 100,000 women are as follows: 18 in Eastern Asia, 22 in South Central Asia and sub-Saharan Africa, 26 in South-Eastern Asia, 26, 28 in North Africa and Western Asia, 42 in South and Central America, 42, 49 in Eastern Europe, 56 in Southern Europe, 73 in Northern Europe, 74 in Oceania, 78 in Western Europe, and 90 in North America. [167] Metastatic breast cancer affects between 19% (United States) and 50% (parts of Africa) of women with breast cancer. [168] The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. [169] [170] Breast cancer is strongly related to age with only 5% of all breast cancers occurring in women under 40 years old. [171] There were more than 41,000 newly diagnosed cases of breast cancer registered in England in 2011, around 80% of these cases were in women age 50 or older. [172] Based on U.S. statistics in 2015 there were 2.8 million women affected by breast cancer. [161] In the United States, the age-adjusted incidence of breast cancer per 100,000 women rose from around 102 cases per year in the 1970s to around 141 in the late-1990s, and has since fallen, holding steady around 125 since 2003.
    BRCA1, BARD1, PIK3CA, BRCA2, ESR1, TP53, CDH1, CAV1, PTEN, ERBB2, CHEK2, BRIP1, PALB2, ATM, EP300, FGFR2, AKT1, KRAS, RAD54L, PARP1, ROR1, STAT1, FOXA1, ESR2, NOS2, CASP8, AKT2, FGFR1, NOTCH1, HRAS, RB1, CDKN1B, FGF3, NCOA3, FBXW7, PPM1D, FN1, RAD51, IGF1, MMP1, MDM2, NQO1, PHB, PTHLH, AR, BAP1, GATA3, TBX3, FLT1, NOTCH2, GPNMB, RB1CC1, FGF4, IFNB1, PLA2G4A, NCOR1, PDPK1, ZNF366, MYH9, ADAR, SREBF2, ICAM5, APC2, GRIK2, STARD8, NRCAM, TOX3, MSH6, NBN, ERBB4, ABCC1, RAD51B, MDM4, FTO, ZNF365, COL7A1, ZNF432, NOP9, ARID1B, LSP1, CDKN2A, HOXB13, HADHB, LGR6, STXBP4, ZMIZ1, OLA1, NR2F6, SORBS1, YBX1, GPX1, XRCC3, AURKA, XRCC2, NAT2, CXCR4, GRB7, RECQL, CXCL12, SNAI2, GJA1, PIN1, KLK10, STMN1, BCL2, CCND1, DKK1, RAF1, XBP1, CAT, BAX, PHGDH, PIK3CB, MIR29A, GPER1, BMP2, MIR206, BRAF, BCAR1, ABCG2, MIR222, MIR221, GLI1, MIR214, APOBEC3B, ADAM12, CCNE1, WWOX, BMP4, MTDH, MIR200C, MIR200B, ZEB1, LOXL2, LEPR, LEP, SNAI1, AGR2, SULT1A1, WT1, CYP1A1, IFNG, PTGS2, ETV4, EZH2, CXCL8, TYMS, F3, CYP24A1, CYP19A1, CYP17A1, PAEP, CYP3A4, IL6, CYP2D6, IL24, ZEB2, CYP1B1, THBS1, FASN, TGM2, JUN, IL10, ESRRA, SLC2A1, E2F1, UBE2C, EGFR, EGF, TOP2A, SLC5A5, EDNRA, TP53BP1, TP73, IDO1, ERBB3, TNF, ABCB6, EPHB4, PAK1, DNMT3B, DNMT3A, SERPINB2, DNMT1, CTNNB1, KEAP1, CST6, RAD51C, COMT, IGF1R, TFAP2A, SNCG, MIR10B, YAP1, MIR126, KRT5, TERT, FOXM1, FOS, MIR141, MIR145, MIR146A, SERPINB5, CHEK1, MTOR, SFRP1, VIM, VEGFC, IL1B, TFRC, SLC39A6, FOXP3, MALAT1, CSF3, CSF2, CSF1R, CSF1, SIRT1, KDR, NISCH, PGR, IGFBP7, IGFBP5, ABCB1, CLDN4, VDR, BCAR4, NDRG1, BAG1, MIR205, NOTCH3, ABL1, H2AX, ADAM10, APRT, MST1, CLDN1, MMP9, NCOA1, PRKAA1, SETD2, AREG, TNFSF10, PRKAA2, STAT5A, INPP4B, GSTP1, HPSE, PDCD4, JAG1, SPP1, MAP3K1, ARID1A, RARB, MMP14, STAT3, NOS3, MTR, MKI67, MMP3, MMP2, HSP90AA1, AHR, NRG1, HRG, HIC1, HIF1A, MRE11, RARA, SOD2, SRC, MTHFR, MAP2K7, NOTCH4, NHS, BCAR3, APC, GSN, HMOX1, ETS2, TUBB3, PER2, KCNIP3, CUX1, NF1, ADRA1A, WNK1, PPARGC1B, RELA, TEK, DHFR, KIT, MIR342, SLC2A5, ANKRD30A, IKBKB, CADM1, MIF, MIR152, HMMR, NRIP1, SLCO1B1, SFRP2, KRT8, HES1, APOBEC3A, EMSY, RPS6KA3, MIR429, EPOR, DDX3X, FLNA, GPI, LEF1, TXN, RNF115, PIM1, CD40, FABP4, FST, ATF2, LAMTOR5, ALK, MIR127, RASAL2, CDH5, PLXNB1, PER3, SLC22A18, KDM3A, CXCR5, MIR301A, MAP2K4, PTGS1, RBM3, CPT1A, DLL4, KCNH1, CD74, PRC1, MIR489, CFL1, NET1, DLEC1, NCOA2, BIRC5, H19, ENO1, SGK3, KRT14, NF2, TOP1, MME, KRT18, MIR132, PER1, TIMELESS, C1QBP, RAPH1, FHL2, TFPI2, NR2F1, ATP2A3, MIR10A, CCL20, HP, MFGE8, NEDD4, PFKFB4, JMJD6, FOLR2, SULF2, WNT10B, FGF10, GPX4, SLC16A3, STC2, DDIT3, BCL2A1, HOXB9, RPS6KB2, OCLN, ABRAXAS1, EIF4A2, LHCGR, SHMT1, PRDX5, FLNB, RPS6, GAB1, PBRM1, LDHB, GZMB, MYOD1, BCHE, KMT2D, CDKN2C, CLSPN, FOXQ1, PDLIM7, GPX2, ARRDC3, MSI1, CLCA2, CSNK1D, ACHE, DEK, ECT2, PLD2, ADAMTS1, NORAD, DPYD, ELK3, H6PD, PTPRC, THEMIS2, FKBPL, PLS3, TACC2, AKAP9, CENPF, CNR2, NAA25, SERPINE2, SLC35A2, GPC1, ROBO1, HDAC4, MAL, ABCA4, BIRC2, BMPR2, XDH, RRAD, CBFB, CXCL9, CLIP1, FABP7, ARFGEF2, TNIP1, HDLBP, TENM1, MED28, SFRP5, EFNA1, DSC3, BCL11A, NFKBIA, TMPRSS6, SLCO2B1, SRARP, RARG, EXO1, APCS, NQO2, ACVR1, ERCC6, MAOA, ANGPTL4, FBL, HDAC7, ADAM33, TRIM29, CDC27, HHEX, MECOM, AKAP12, EPB41L3, LPAR1, OCA2, GABRP, CDA, CUL5, IRF8, LIMD2, DES, KLK15, ARF1, SRSF1, SLC2A2, NSD2, RGS2, GSDMB, EREG, ENPEP, PPM1E, FOXP4, LLGL2, EFEMP1, MTMR3, EIF2S2, NUP214, AMFR, MAGEA4, PCDH8, FGD5, MIR101-2, DDX10, BTK, REPS2, ARAP3, ZNF404, TP53BP2, PLCB1, EHMT1, MEIS1, HSD11B1, MAP3K13, FBXO8, NCOA6, ATG10, CASP7, BGN, CHD5, CIC, TCL1B, ACCS, FAAH, CTU1, NUP98, ARHGDIA, TCP1, MICAL1, FUS, PDCD6, H4C1, EDNRB, SEMA3A, MMP10, RPS4X, AFP, DLL1, MIR24-2, ABCB10, UTS2R, MFAP5, CDH2, IFNA2, DIP2C, DAP3, GEN1, ZFYVE26, UMPS, KCNA5, CLPTM1L, CFP, SUV39H2, SLC2A10, SLC10A6, BCORL1, DMD, BTN3A2, HNRNPK, HNRNPL, PTPN14, HOXA4, GPC2, HEY2, SUSD3, PTPRD, ACADM, DVL3, TICAM1, ZNF569, MAGEC2, B3GALNT2, SLC6A3, MT3, NDUFS3, TEKT4, ERCC3, DIO3, P3H2, NIPBL, PRRT1, ZNF436, ARHGAP11A, HLCS, FLACC1, JAG2, AHSA2P, SIM1, PDZK1, ZC3H11A, SLAMF1, SRGAP3, SPATA18, G3BP2, MACF1, NSMCE2, AKAP8, MED12, RIC8A, ADHFE1, PDGFA, DEPP1, SLC28A1, RMND1, HEYL, IBSP, RSPO3, SLC6A5, DOP1A, AQP8, PRODH, CFL2, MAGEA1, HELQ, RPRD1A, POU2F1, RXRB, RPS9, WARS1, LBX1, BMP1, GALNT16, COTL1, MRPS23, ASL, DHX32, ZNF668, SCP2, TP53I3, HSPA1B, CCNH, PPA1, ELP3, TRERF1, H2BC4, RCCD1, SPAG6, TBXAS1, LIPE, UBD, SIK3, KAT6B, VWF, MNX1-AS1, PRPS1, TREM1, MIR31HG, MAGED2, MCF2L2, CXCL3, RAC2, SYNJ2, APPL1, VEGFB, CRHR1, LRRC3B, MANEA, PRPF4B, GRIK3, CEP85L, COL11A1, EPG5, NMBR, TAS2R13, GKN1, HERC2, SMC6, INPP5K, MACIR, C16orf58, HEY1, RUFY1, SMARCD1, EIF5, CELA1, SPTLC1, SLC9A2, FNDC3B, CXCL2, SYT3, TLL1, NLE1, SMARCA4, GRIN2D, GDF10, SPAST, ZNF541, EVL, HOXA3, GRM6, TSPAN4, STX5, NECTIN2, PLEKHA8, GOLGB1, ANKRD29, NOA1, FARP1, SURF1, RAP1GAP, RFC4, MICALL1, LZTS2, B4GAT1, NPBWR1, L3MBTL3, STX12, DYNC2H1, MFSD9, TMEM25, UNC45B, SLC8A3, HOOK3, NFYC, ABHD12B, POP1, GNAI2, TMTC4, WDCP, SMOX, H2BC12, KBTBD8, SIX4, RANBP1, ARHGEF38, ZBTB3, LMF2, STPG1, PKDREJ, OSBPL11, SORCS1, HGF, GNB1L, THBS3, FCRL5, TESK1, UGT1A9, TCF7L1, IGBP1, FAM83F, ADAT3, HOXD11, DDX59, COG3, TECTA, CPSF3, EIF3M, ZNF281, FCRL3, PCDH20, PIGS, TMEM125, TSC22D4, MRPL9, CFHR5, FAM189B, DNAJC24, HK3, EFCAB13, SORL1, FAM210A, SCGB3A2, NLRP8, WDR88, FKTN, KLHDC7A, AGAP2, OR12D3, C1orf87, PPHLN1, ZNF318, INHBE, H1-2, GTF2A1, SPTAN1, CD109, ARFRP1, ALKBH8, BOC, MPLKIP, PHF7, RASL10B, RALYL, LONRF3, SCARF2, ZNF644, SEMA5B, NLRC5, FASTKD3, PUS1, SPOCD1, TMEM39A, TLE3, HNRNPR, SLC25A51, FSCB, TFAP2D, UBLCP1, FAM131A, TXNDC15, METTL6, RTP1, TRMT10A, VPS72, RASGRF2, OBSCN, LDHAL6B, G6PC, GUCY2F, STAT4, GABRA4, PADI3, GUCY1A2, ATP6AP1L, TMED1, DNAJC21, SP110, SLC22A9, OR1N1, DTX3L, PHKB, CLCN1, CLIC1, ZNF532, KPNA5, GALNT5, MAGEE1, CNGA2, ZSWIM5, PPP1R12B, OXSM, ZFP64, SHROOM2, ZNF646, ABCB8, SMARCAL1, PDZD4, SPATA21, KANSL1-AS1, GPR45, CDS1, KIAA1324, PIK3R4, LRRC7, LAMA2, NUP133, WNT1, KTN1, MET, PPM1F, TRMT2A, CHRND, ARAF, YY2, HAPLN4, MRPL13, KRTAP10-8, SETBP1, ITSN2, OSTC, ZNF277, ARHGEF4, CRX, SIPA1L1, COL19A1, CDH20, CRYAA, KCNJ15, C5orf34, PRRC2A, MROH7, LINC00671, KALRN, C4orf50, GFRAL, WFDC1, MRPS28, NUDT2, ACAP1, ARTN, PPP1R3A, SLC7A7, PLEKHD1, APOC4, MAP3K6, MIA2, WBP4, N4BP2, INA, VPS39, EOMES, MYH1, FEM1C, SLC17A6, MIR345, IL1RAPL2, CCT5, PURG, SCNN1B, MOSPD1, MAN2C1, TBC1D9B, LRRC37A2, PANX2, PLAU, MCOLN1, ARFGAP3, UBR4, CMC2, ZDHHC4, KLHDC10, CUBN, MRPS22, OTOF, ARHGAP29, C1QB, AKAP6, CNNM4, MYC, PLOD1, SPEN, KDM1A, ZNHIT2, FXR1, PCDHB15, RRP9, LGALS2, LRBA, LRRFIP1, TOR1AIP1, POLH, AVPR2, GGA1, POLR2F, PRICKLE3, ATP7B, NID2, ATP6V0B, CDH10, COLGALT2, DYSF, PRRG1, PCDHGB6, PABPC1, RIBC2, TAFA4, MAGOHB, RIF1, SYNE1, FRMPD1, ZNF22, LLGL1, ZNF75A, DAZAP1, PNLIPRP1, MED14, CD2, TRAPPC8, GGA3, KCNJ1, RHD, SH2D3A, TRPC4, DNASE1L3, NME8, BEND7, PXDC1, DPAGT1, RNF182, HEPACAM2, KIF6, EHBP1, RPL31, ADGRF4, NSUN6, SLC39A12, DNAH9, ACTA2, PGBD3, MAP7D2, MRPL19, RGL1, ALS2CL, CATSPERE, ITGA9, HEATR9, TTC3, HSPA14, ACY1, TANK, SNX32, RPLP2, NDUFA3, THOC5, ZNF438, ACO2, ZNF25, EEF2, SSNA1, GPR180, ABCA3, USP54, EEF1B2, RFX2, SYNE2, KRT76, MAMDC4, VPS13B, TNS1, EGR1, RPL23A, ASTN2, FAM217B, TP63, DAW1, ANKEF1, TPM4, ANAPC5, XIRP1, TPTE, GIMAP1, ADAMTS19, NIP7, DTX3, PACC1, UQCC1, NDUFA8, NUDT17, HOOK1, BOD1L1, RCE1, CNTN6, MRPS7, ALDOA, CLUL1, KCNT2, TMEM161A, TREML1, TRIML1, ELP1, KRTAP21-1, ZNF546, RPS7, NDUFA2, DGKE, NLRP14, STRBP, UPK1B, DDX18, CUTC, ZNF667-AS1, TAX1BP1, CTU2, AP1M1, RPS8, ATP8B1, AFF1, MTMR8, KIF16B, ANK1, WDR53, CST4, CTIF, ANK2, NLRP9, TRAPPC12, TRMT11, DGKG, JAKMIP3, PDE2A, CYB5R4, OTOGL, EXOC3L1, CAVIN1, ZCCHC14, SKIV2L, ANKRD34A, APOL1, GOLIM4, DBN1, CLASRP, RNF149, EIF6, LRRC37A, KRTAP20-1, H2AC21, DDO, HSD17B8, SBNO1, UTP20, THRB, ETV6, ESPL1, TCF7L2, ADSL, CASC16, MSH2, MRTFA, MLH1, MUTYH, SLC19A1, PVT1, PRSS46P, SLC4A7, TGFBR2, RET, CCDC170, PMS2, TET2, COL1A1, SIAH2, ITPR1, ARHGEF5, CASC9, RNF146, TAB2, BABAM1, ANKLE1, EBF1, CDKN2B-AS1, FANCI, PEX14, HSPG2, RALY, PDE4D, POU5F1B, DCLRE1B, CCDC88C, ELL, ADAM29, CASC8, FBXO11, SLC22A3, SOAT1, BRCA3, SLN, SMUG1, IL4, ZNF410, MMP13, MMP11, TBC1D9, JAK2, MMP8, MMP7, HSD17B1, IL2, NCL, NLRP2, CCN1, JUNB, JUND, COPS5, SHBG, MRPL34, IL1A, TRPM7, MUC1, CD82, NEU1, SIX1, IL17RB, IL17A, REN, TNIP3, HEATR6, MT1E, IL15, PGRMC1, RPE65, SOX9, IL18, RPS6KB1, SLC9A1, BRD4, IRS1, SOX17, CXCL10, ITGA6, INSR, COX2, GAS5, IL11, CXCR2, SKP2, MPO, MEG3, RASSF1, SLC16A1, SOX2, ITGB3, NEK2, LILRB1, HPGD, ITGB1, SOX4, MRC1, LAPTM4B, NME1, MSH3, TRNE, MTRR, IGFBP3, RRAS, ROS1, LPA, MAPT, RETN, S100A9, CCL2, S100A8, S100A7, S100A6, S100A4, LOX, MCPH1, CCL5, LNPEP, CCL18, VTCN1, HTC2, LMNA, MCAM, IFI27, BECN1, NFKB1, MGMT, SMAD3, UGT1A1, MUL1, MYBL2, EPCAM, SUB1, SLC12A9, SLC52A2, SMAD2, SMAD4, S100B, SATB1, TNC, ACKR3, SCD, MYB, ABHD8, MYD88, FSD1, CCL21, MCL1, LIG4, ANO8, SET, SEMA6A, PREX1, KRT19, MFAP1, DDA1, CIP2A, RRM1, IGF2, SLC52A1, KISS1, SCGB2A2, IGF2R, HSF1, ICAM1, RNASE3, BANP, IGFBP2, SELE, INTS2, LASP1, HSPA4, MYO9B, SIRT3, NGF, LIN28A, SDC1, CKAP4, LGALS3, NFE2L2, HSPB2, HSPB1, LGALS1, SHROOM4, LDHA, LCN2, PHB2, PPARGC1A, HSPA5, DICER1, NAT1, SP1, MIR29B1, MIR34A, MIR31, MIR30C2, CASP3, MIR30A, NPEPPS, CASR, RUNX2, RUNX1, PSMD9, MIR29B2, RUNX3, MIR27B, CMA1, CCK, MIR27A, ZNF217, PLAT, CCNB1, PSAT1, CCND2, PLAG1, MIR223, MIR22, NR1D1, CLOCK, PLG, BTG2, CALR, MIR93, MIR373, PPIG, KL, PML, MIR340, CD274, SLC9A3R1, ADIPOQ, BSG, PSG2, MIR335, KLF5, COX5A, BTF3P11, GRAP2, CAPN5, GSTO1, AIMP2, CA9, CA12, USP7, CALCB, CALCR, MIR96, PLK1, MIR210, MIR21, NCOR2, XPC, CDKN1A, PIK3R1, CDKN2B, PIK3CG, PIK3CD, CEACAM5, MIR182, MIR18A, CEACAM3, CEACAM7, MIR17, IKBKE, SERPINB6, MIR155, WNT5A, MIR148A, CHI3L1, CHKA, MIR143, MIR142, MIR140, CISH, CKS1B, MIR139, SPARC, PTH, CDK6, CD34, CDK4, CD36, MIR204, MIR203A, ZFP36, CD44, CD47, TRAF4, CD68, MIR200A, MIR20A, CD151, CDK1, MIR19B1, PKM, KLK4, CDC25A, MIR195, PITX2, CDC42, ERVW-1, XRCC4, PIP, MIR191, CDK2, XRCC1, BMP7, BMP6, FOSL1, PCAT1, ERVK-20, COMMD3-BMI1, LMO4, ADRB2, MAPK3, MAPK7, MAPK8, TMED7-TICAM2, AGER, AGT, AGTR1, NR1I2, ALB, ALCAM, ALDH1A1, CD24, PGAM1P5, SPHK1, AKR1B1, SQSTM1, HOTAIR, AMH, MBD2, MCAT, DIRC3, MAPK1, ERVK-18, PTPA, LINC-ROR, PRKCB, H3P10, H3P23, EIF3A, IRS2, PRKCA, DKK3, ABO, TNFRSF11A, ERVK-32, MTCO2P12, TNFRSF10B, TNFSF11, ACTB, PRKAB1, DLX2-DT, NRP1, LINC01488, LINC01527, LINC02143, LINC01416, PRKDC, ADH1C, HPGDS, ADM, CCR2, ANGPT1, BMI1, AXIN2, POU5F1, MIR499A, ATF3, MIR497, PROS1, LPAR2, PON1, TAM, ATR, HACD1, MIR20B, BACH1, RNU1-1, PTTG1, KLK6, BCL6, KLF4, HMGA2, MIR375, BDNF, CD163, CEACAM1, SLIT2, PSEN2, BLM, NEURL1, STS, ANGPT2, POU5F1P3, HSPB3, SGSM3, ANXA1, ANXA2, ANXA5, ANXA6, FOXP1, SOCS3, APEX1, XIAP, MCTS1, PELP1, APOE, PRL, KLK3, FAS, CLDN6, PRLR, DIRAS3, UCA1, PPARG, MTA1, EMBP1, POU5F1P4, PPARA, POLDIP2, CLU, CCR5, AGO2, NR5A2, MUC16, CAP1, FUT4, ODC1, CARM1, XRCC6, GABPA, GAPDH, MYBBP1A, CIB1, RAD51D, ZNRD2, PAK4, GH1, GHRH, TAZ, CXCL13, MAP3K7, ABCC11, GLS, ADAM17, NTRK1, TAC1, ARFGEF1, NT5E, PRRT2, PRMT5, OGG1, FOSB, EMID1, TGFBR1, FDXR, FEN1, FGF1, FGF2, SPDEF, FGF7, CDYL2, RAC1, FGFR4, TGFB1, TGFA, FHIT, MUCL1, OSM, TFF1, DLC1, GDE1, FOXC1, ANIB1, TFAP2C, FOXO1, FOXO3, TNFRSF11B, SYK, SFN, AHSA1, HDAC1, KHDRBS1, HFE, SSTR4, CXCR6, SST, HK2, HLA-A, CTCF, NECTIN4, DCTN6, HLA-G, COL18A1, HMGB1, NPY, SRCIN1, KRT20, HMGA1, HNF4G, CD276, NES, PPP1R2C, KDM5B, HOXA5, SEPTIN9, WASF3, ST14, ARHGAP24, CXCR3, PLVAP, PDLIM5, STK11, POSTN, GRB2, GRID1, GRID2, GRN, BRMS1L, NR3C1, NRAS, TLR9, CXCL1, GRPR, GSK3B, GSTM1, GSTM2, STAT6, STAT5B, GSTT1, NPAS2, USHBP1, FSD1L, BCL2L12, CHST9, HAS2, CCR7, PTK2B, FANCD2, CYP2C19, CTAA1, TMED7, CCN2, CTLA4, GMNN, CTSB, CTSD, CTSL, FMN1, CYP1A2, PTPN1, CYP2B6, PECAM1, PDCD1, TAS2R64P, PTPN11, CYP27B1, DACH1, PDK1, DAPK1, TWIST1, DCN, ACE, NEAT1, TTK, DHCR24, TICAM2, GSTK1, UGT2B7, PFN1, MIR125A, MIR122, GREB1, PTK2, MIR100, PTK6, LINC01194, COL11A2, VIP, EZR, LINC01376, COX8A, VEGFA, ADAMTS7P3, HDAC9, CLDN7, CPOX, LDLRAD1, CREB1, VASP, UVRAG, CRK, CRP, MAPK14, F11R, BRMS1, SCO2, DLX4, AQP4-AS1, SRA1, PWAR1, EPAS1, CFAP54, PRKN, CNTN3, EPHB2, TLR4, PXN, EPO, TLR1, ERCC1, ERCC2, ERCC4, ERCC5, ESRRB, SERPINE1, ETS1, TIMP3, TIMP2, TIMP1, F2R, F2RL1, SLCO6A1, SYNPR, CTTN, HSD17B7, CBLL2, RNF19A, TSG101, TRPS1, HDAC6, ATN1, PCNA, DUSP1, RAD50, E2F4, TYMP, C11orf65, NAMPT, CYTB, TNFRSF1B, NEK10, PAX9, EPHA2, TNNT3, ELF3, EIF4E, EIF4EBP1, TNFRSF1A, ELAVL2, MTNR1A, LPAR3, BBC3, PYCARD, RNU1-4, WWTR1, MYOF, PAWR, GDNF, PRKD1, CCAR2, CTNND1, IGFBP1, FERMT2, IL1RN, UGCG, CTBP1, CTAG1B, CXCR1, IL13, VCAN, SMURF2, VCAM1, GPR42, ING1, VIPR1, MIR137, MIR149, ITGA5, PTP4A3, ZNF350, CDKN3, MELK, IFNA13, IFNA1, GRHL2, HAVCR2, SULT1E1, TCHP, STC1, GLO1, SSTR2, STARD13, SCGB3A1, VEGFD, SOX10, NR1I3, NANOG, TLR2, EPHA3, TRIM28, TPT1, DUSP4, FSCN1, CYP4Z1, DDX5, CDKN1C, ILK, CDK7, FANCM, BRS3, BCS1L, PIWIL1, XPR1, MIR193B, CCNE2, MEN1, MIR320A, RRM2, CUL4A, PROM1, ADRA2B, CCN5, RHOBTB2, GDF15, ZNF469, CDH13, CCND3, PCGF2, MIR26B, CDC25C, KMT5A, FGF8, MIR183, P2RX5, KLK5, TGFBI, LMTK3, RECK, ANXA3, CKS1BP7, ESRRG, TFPI, FOLH1, MAP2K1, LINC01672, CEBPD, GDF2, TBX2, CCN6, SYT1, ORAI1, CDK10, LOC107987479, ABCC3, CDX2, TXNRD2, CTCFL, ARF6, TLR3, CRY2, CRYAB, MIR34B, MIR30C1, DDR1, CASP9, RASSF7, BNIP3, MIRLET7B, PRSS50, MIR29C, POLD1, ADIPOR1, AXL, USP9X, GAB2, UBE2I, PTCH1, MIR15A, TSC2, CTAG1A, ARNTL, LATS1, MED1, WRN, PAPPA, AKT3, WWC1, SMYD3, RBP1, RPS6KA1, TRIB3, MGP, S100A1, MCC, NDRG2, RAB40B, HOXB7, SAFB, HOXD13, WBP2, MRPS30, SOD1, RAB25, CYP4F3, PRMT1, MMRN1, MSMB, MTA3, IL2RA, MT1JP, FRTS1, RASA1, GORASP1, SLC20A1, PPP1R1B, MT1F, NEDD9, C17orf97, CAMP, LRP1, RFC1, CXCL5, CREBBP, ANO1, S100A14, LIFR, CERS2, CXCL14, CALM1, KDM6A, CCNA2, LIMK1, IRF1, PHLDA1, MIR150, GOLPH3, FSTL1, CEBPB, MIR185, PSIP1, KMT2C, CDK9, ABCC2, CDH3, MIR106B, TSPO, PKD1, GRM1, CDC20, YWHAZ, CD59, LGALS7, MIR17HG, TXNIP, BUB1, MICA, APP, MIR590, APOA1, KMT2A, RBM38, NR0B2, DYRK2, ALDH1A3, MSN, HDAC3, RPS6KA6, UHRF1, MT1A, MT1B, BHLHE40, ADH1B, MT1H, IQGAP1, ACACA, IL17B, SOCS1, MT1L, FASLG, LGALS7B, PRNP, RHOA, BST2, LTA, BIK, REST, INTS6, MIR423, MIR424, KDM4B, MAD2L1, SMAD7, BAD, ROCK1, MIR451A, ATP2B2, ARHGEF2, POU1F1, MBL2, POU4F2, MIR503, FZD4, ZNF423, LUM, EBI3, STARD3, ENG, PVR, MT2A, FLT4, ELF5, EIF4G1, TPD52, OXER1, DNM1L, NR2C2, HSP90B1, TRAF2, TNFRSF12A, GPRC6A, RAC3, ERP29, HAX1, TIMM8A, PART1, TM7SF2, DNER, USP17L2, PRAP1, SIRT6, POLQ, HNF4A, TET1, TFF3, FBLN1, FOXF1, PEBP1, FABP5, PRDX1, HOXD10, RBBP8, FLOT2, HMGCR, PIWIL4, AGFG1, OTUD4, PLAC1, DCTN4, CYP11A1, PTPN6, CYP3A5, CYP2E1, GADD45A, GHR, GLI2, GGCT, NFATC2, STING1, UCHL1, IL6ST, PFKFB3, DAPK2, GTF2H1, GRP, STIM1, NUP62, TMPRSS13, LMLN, ATG7, TCF4, PDGFRB, TXNRD1, MVP, ING4, G6PD, MOK, RIPK1, RXRA, CLDN2, TERF2, KAT2B, POLD3, NMI, IL18R1, NDC80, RNF8, ULK1, RAD21, TACC1, TAGLN2, CFLAR, GPRC5A, PROCR, TBX1, SASH1, SREBF1, RAD52, TRIM21, SND1, NR1H2, SMR3B, TGFB2, PTPN12, MFN2, SHC1, XIST, LRIG1, ST8SIA1, SIPA1, WNT7B, ISG15, WDR5, SETDB1, OPN1LW, WEE1, UCP2, VAV2, RAB31, QSOX1, PTN, UTRN, UGT2B17, SRSF3, YY1, SPG7, TES, CITED2, THRSP, MLRL, AURKB, BCAS2, IL32, KDM2A, SOS1, TRIM13, NR4A3, CHST3, LRPPRC, RALBP1, CCL22, PRDM2, PSMD10, MLLT11, TRIM25, PTPN13, WWP1, PEA15, ID1, MIR148B, FKBP4, FOXF2, FOXC2, FLI1, LY6K, FOLR1, NEUROD1, AZIN2, TP53INP1, ORAI3, FYN, GATA4, GC, MIR449A, TSLP, GHSR, PRKCD, KRT88P, RERG, PIWIL2, GNRH1, NM, MRGPRX4, GSTO2, NUCB2, MED19, BTG1, E2F2, CYP4Z2P, P2RY2, ELANE, PRIMA1, EPHX1, UIMC1, GPR151, MIR381, EYA2, NTRK3, FABP3, NRF1, FANCC, FAP, FAT1, KLF17, FCGR3A, GNRHR, NR0B1, BEX2, KRT8P3, GALNT14, MB, DHRS11, ASAH1, IGFBP4, SLC2A4RG, MIR455, CDCP1, IL7, ARR3, MECP2, RHBDF1, MT1IP, IRAK1, ISG20, PNPLA2, CXADRP1, ITK, ANKRD36B, AICDA, HSD11B2, PBK, AVP, HDGF, SLX4, MIR409, MIR485, MIR146B, H2AZ1, SOX7, ZNF654, MT1X, MT1M, MT1G, ATF4, SHARPIN, MST1R, ALOX5, TRPV6, MIR494, HLA-DRB1, NR4A1, HOXA1, ZNF703, DPP4, MRGPRX3, GATAD2B, MIR19A, CSNK1E, CD80, HUNK, FLVCR1, MIR211, KLK14, LOC111589215, LAMTOR2, VN1R17P, HSD17B13, CTSK, IL22, CTSS, CXADR, GADL1, RGCC, CRYZ, MIR23A, EFEMP2, CETN1, CALM3, MIR107, CALM2, MIRLET7C, COMP, POLG, CALCA, EEF2K, MIR98, MIR99A, PPARD, CLDN3, CDH11, CRMP1, SERPINF1, CGA, DECR1, CAV2, PDGFRA, SDF4, MRGPRX1, PC, BRINP1, PRKAR1A, GPR166P, CBR1, MIR23B, CYP2C8, CCL27, HOXA10, MIR192, EBAG9, CAMKMT, MIR519D, HPN, KPNA2, LAG3, ZFHX3, KIFC1, PPP1R13L, KLF8, KLHL1, FOXA2, PRDM14, CDK3, CDK8, MIR655, SSX2, RGS6, CEBPA, MIR638, MTUS1, MAP1LC3B, HLA-C, MIR7-2, SELP, XK, HLA-DOA, EBP, SRY, MIR193A, NMU, HSD17B2, MIR7-1, MS4A1, USP14, IL25, FZD1, ITGB4, SLC16A4, ITGA2, PIM2, RPP14, PRMT2, KRIT1, CD14, SLC6A4, CD9, MIR215, RHOC, EIF3E, TBPL1, SLCO1A2, MIR7-3, MIR296, ABCG1, GALNT6, APOB, SGK1, HSPA8, HYAL1, CD40LG, IARS1, CD33, SCUBE2, SLPI, HAMP, AQP3, AQP5, JAK1, IL1R1, DMBT1, MIR144, BID, KIF14, CYP27A1, EYA1, CYP2C9, F5, TIAM1, THY1, FANCA, CYLD, THRA, ACSL4, AKR1A1, FBLN2, FBP1, FGFR3, SCGB1A1, TFF2, SDCBP, BCL3, CDK2AP2, MSLN, SCGB1D2, EPHB6, DMP1, HDAC5, MIR135B, BCL2L11, NPNT, E2F3, DDT, FSIP1, ECM1, LYPD5, S1PR1, EDN1, AMOT, EPHA10, DST, EPHA1, MIR374A, EPHA5, PTP4A2, DCD, PWAR4, CST3, CTHRC1, SNORD14B, VDAC1, GCLC, TACR1, MAP3K8, AZGP1, UBASH3B, VHL, GOT2, TSC1, SNORD35B, ECRG4, MIEN1, MIR106A, GSTA1, MDC1, MIR202, CLCN3, HDAC2, SNORD14C, SNORD14D, SNORD14E, CLEC10A, TFAM, FMR1, UGT8, TERC, USP4, PCLAF, VAV3, SAT2, GATA2, B2M, SEMA4D, CRH, VAV1, IL33, KAT5, CRABP2, LIN28B, GFRA1, KLF6, GPC3, CCN4, PTPRO, ZBTB7A, TNFRSF10D, SIN3A, MIR190B, PTPRJ, POT1, PAX6, PTX3, RPS27, PAX5, RRS1, ARHGEF7, SYCE1L, TNFRSF10A, PAK2, PCSK6, PTPRA, MIR708, GNL3, PTGER4, SAI1, PLCG1, PHLPP2, PTBP1, KDM4C, AKR1C3, MCM2, ADAM15, SCGB2A1, CDK19, DELEC1, PDGFC, PGF, ASAP1, RSU1, PAG1, MUC4, PA2G4, RMDN3, KLRC4-KLRK1, ARID4B, TMX2-CTNND1, CDK12, BCAS3, SH3BP4, DENR, NEK3, FBLIM1, NKILA, CORO1C, PLAAT4, ANLN, PRAME, SEC14L2, RASGRF1, CCN3, ALKBH5, GINS2, DSCAM-AS1, NSD3, RORA, SIRT7, SNORD15A, NCSTN, BRD2, PINX1, CEACAM6, ACTN4, NCS1, SF3B1, ANGPTL2, GABARAPL1, SF3B6, SEMA4C, MAGI2-AS3, SMAD1, SPRY4-IT1, LATS2, TACSTD2, MUC5B, NLRP1, PPIA, H3P8, TPX2, DANCR, ZHX2, WASL, PMP22, POLB, KLRK1, TBK1, SMURF1, FOXD3, RHBDD2, SALL4, CHPT1, NUMB, LPO, F2RL3, PRKCZ, LGMN, DYNLL1, EDIL3, MACROD1, ATAD2, PRDM1, XPA, XRCC5, RNF41, TNK2, OXTR, ELK1, TPM1, MIR339, MKNK1, NXT1, ZFP36L1, PDIK1L, RAB27B, P2RX7, LINC01638, EEF1A2, CCDC6, EEF1B2P2, AGR3, CDK5, RAB27A, POMC, NRP2, MIR338, TNKS, RMDN2, PLB1, TOB1, TLR5, NUPR1, CD63, PPP1R1A, TPTEP2-CSNK1E, MIR216A, SOCS2, MIR224, MIR378A, HYAL2, SOX18, FANCF, RABGEF1, NPM1, PGR-AS1, CHD1L, BHLHE22, PRG2, LGR5, FGF13, RBMS3, PIMREG, MIR382, SIGMAR1, SERPINA3, RAP1A, MAPK9, EIF2AK2, MAP2K5, MIR190A, BRI3BP, FLOT1, MIR212, TSPAN13, EPS8, ERN1, MZF1, PPP3CA, BGLAP, ABCC4, H3P17, NTSR1, STUB1, DDR2, F2, MIR326, XBP1P1, TPO, UBE2N, PRPF31, CSK, MTSS1, KDM4A, VTN, SLC40A1, UGT2B15, CSPG4, PIK3R2, PI3, CCR6, WAS, ADAM9, CTSO, MIR134, PRRX1, MIR136, MNS16A, TNFRSF6B, CSH1, RNF144A, UQCRFS1, PTPN22, ROCK2, FZD5, AOC1, PLOD2, LINC00511, COX11, CPB2, PLCD1, PSMD8, ADAM23, OSGIN1, SERTAD1, NOC2L, CA2, RACGAP1, PLA2G1B, KMT2B, CSE1L, FFAR4, PTPN2, RNF168, LOC110806263, CFTR, DLD, CERS6, ABCA1, SARDH, MIR181C, LETMD1, DNASE1, DPEP1, CHAF1A, DCDC2, TRH, TRAF6, ABCC5, BUB1B, H3P9, MPEG1, CDO1, DACT2, MYLIP, ZFAS1, CGB3, TMED10P1, ENPP2, BPIFA4P, CHUK, TWIST2, CD55, EIF2AK3, WNT2, ENPP1, DAP, RCC1, TYK2, VPS51, RMDN1, WDR1, LOC107228383, ANKRD11, SLC13A5, BRD7, TRIM59, LDLR, KDM5A, MAPK12, RTL10, FASTK, MIR483, MAZ, ADIPOR2, BAG3, BHLHE41, CUL1, STIP1, IDUA, MIR484, MIR486-1, RRP1B, TMED10, SPHK2, CUL3, MRPL36, MIR671, KIF2C, IL6R, TLK2, KLK11, FOXK2, HSP90AB1, LYVE1, HSD17B4, HOXA9, SETD7, ITIH5, SLC19A3, SRD5A2, PTGES3, RPS14, HNRNPA1, MIR495, SYBU, MTHFD2, DDIT4, MYDGF, RAB11FIP1, ASRGL1, KITLG, HOXC8, NAA10, HOXD@, HPR, HDAC8, CD46, VASH2, CSMD1, MARCKS, SRPK1, FZD7, CXCL16, ANPEP, PTENP1, CCL8, LMO2, KLK1, KLK2, DDX20, CCL17, CEMIP, MIR605, MIR663A, KRT17, LALBA, MIR608, PADI2, MIR618, SELPLG, LIF, RPSA, MIR630, LBR, SPOP, SLC13A2, KCNMA1, SHH, SIRT2, SLC6A8, AKR1B10, SLC6A2, DAAM1, NUS1P3, PCBP4, IRF6, LTF, SCN5A, ISL1, SLC1A5, KCNJ3, GOPC, RGN, ITGAV, ITGB2, PAK5, LRP6, SIM2, ST3GAL1, MIR542, MIR421, HLA-DQB1, SPINT1, MIR302A, PRDX2, ESRP1, WRAP53, MASTL, ATAD1, SLC34A2, MRPL28, AFAP1-AS1, TDO2, CBX2, EPSTI1, EGLN2, NELL1, SPZ1, KISS1R, ST6GALNAC2, PRMT6, SPAG5, CYTOR, ABCE1, CDK5R1, DOT1L, ANP32B, RPS6KA5, CBX5, SEMA3C, MIR448, BAK1, MTA2, BCAS1, NCAM1, ITGB3BP, CGB8, PES1, KSR1, TAT, GJB2, CGB5, GAST, RNASEL, HOTTIP, NEFL, MIR452, GPX3, MYCBPAP, QRSL1, C20orf181, NUS1, ATP6, LARP6, ALOX12, ST6GALNAC5, HIVEP1, MSR1, EGLN1, CHDH, NME2, CD200, SAGE1, MIR493, MMP17, RBBP7, NFKB2, NGFR, CREB3, SCRIB, ANTXR1, MTTP, CYGB, MUC2, KLLN, MIR425, NLRP3, MIR1246, GSTM3, TIMM17A, MAP3K14, MIR34C, PRB2, CCAT2, MIR544A, GATD3B, TRIP10, MIR660, MIR30E, MIR379, MBTPS1, MIR661, HNRNPA1P10, ANGPTL1, PANDAR, MIR361, MIR564, NOL3, CDR1-AS, SART1, TNFRSF10C, CISD2, UBE2L6, MIR506, MIR502, FHL5, TRAP, RAB11A, MIR324, MIR876, MIR216B, DDX21, MIR940, MIR526B, RN7SL263P, MIR944, MIR492, MCM3AP, MAP4K4, MIR133B, AIM2, MIR760, POTEKP, CBFA2T2, MIAT, XRCC6P5, POTEF, SNHG14, MIR323B, FGF18, MIR372, MIR370, SNHG6, POTEM, LINC02605, MIR330, MIR1271, WASF1, MIR1258, BLID, TEC, APLN, TRIM24, MIR300, TNFSF13, GLS2, PTGES, TCIM, TMPRSS4, SUSD2, CHFR, ENAH, TENM3, NSUN5, HIF1AN, STAB1, AMBRA1, FERMT1, HJURP, SLC39A9, BRF2, MGA, IMP3, NAT10, TRIM62, SATB2, CEP55, CDCA8, PPP1R13B, KIF26B, RNF31, AKIP1, PMEPA1, MIR25, SMG1, WDHD1, LZTS1, PLEKHB1, WIF1, AKAP13, ZBTB4, ZNF398, MIB1, PARK7, ACOT7, OIP5, CASC3, AHRR, RRAS2, ITGA11, RAB22A, CBX8, ARFGEF3, MLXIP, TP73-AS1, TWSG1, CIAPIN1, CEACAM19, TUG1, KCNH4, CT55, CYP2W1, KCNK9, GLCE, ASCC1, SOST, IL20, CHST11, NOX4, KLK12, SH3KBP1, NOP53, FBXO22, PSMC3IP, HSPB8, SENP1, CARD10, SNORD44, RNF11, DNAJC2, UBE2T, GIT1, TMEM97, POLL, CACYBP, UBR5, NELFB, GTSE1, PTOV1, CASZ1, NSUN2, TRIM44, LEPROT, PRMT7, AMACR, WNT4, ZMYND8, ERRFI1, FXYD5, TMEFF2, CXXC5, SHC3, RSF1, RTRAF, LSR, SUN2, UFM1, ACKR4, QPCT, VTA1, SULT4A1, NTN4, TRPV4, SENP2, TMEM132D, PDCD6IP, PARP3, MARCHF8, SLC25A43, PRSS55, PTPRU, ACTR2, BCAP31, CNTN4, IL23R, G3BP1, C1orf52, LYPD4, LINC00052, BCDIN3D, PSME3, CACUL1, FOXR2, SPRY1, TAAR1, FSTL3, KCNH8, ACVR1C, IL27, CASC2, NR2E3, DCAF1, PRDX6, MIR199B, MIR196A2, MIR188, MIR154, MIR130A, ST18, MIRLET7G, RAB11FIP3, C4orf3, MIR100HG, TINCR, TMEM189-UBE2V1, TMEM189, MAML1, NDUFS7, MACC1, ACTBL2, SCARA5, HOXA-AS2, HS3ST2, NR1H4, MSI2, C10orf90, ERLIN2, TUBA1B, PEAK1, NOL9, BRD8, FAT4, SPIN1, WDR77, TRPM8, AHNAK, MARCKSL1, TUT1, TNS3, TMPRSS3, RIPK3, COP1, ADRM1, NOD2, LRRC4, TNN, MIIP, KAT7, RINT1, AFAP1, PBOV1, LPCAT1, LINC00472, DHDDS, HOPX, KLHDC7B, CRB3, NAF1, CREB3L1, CIB2, PYGO2, WNT3A, SLC22A16, HTATIP2, SNHG7, PDPN, ZC3H12A, IGF2BP1, RPAIN, RHBDD1, IGF2BP3, IGF2BP2, VMP1, CLDN16, HM13, PDCD1LG2, PDGFD, SLURP1, H3P40, HNRNPM, MYO10, E2F5, NOS1, NONO, NOP2, TNFAIP1, EFNA5, EFNB2, DRG1, AMPH, TPI1, EIF4A1, CRISP2, TTC4, ELAVL1, MYLK, CCT3, MXI1, MVD, TRPC1, ELN, TRIM37, TRPC5, MARK2, EMP1, DVL1, NUMA1, SLC25A5, OPRM1, TCF3, DDB2, SLC25A3, PGK1, TRA, CDK14, PF4, GSDME, TERF1, DKC1, NR2F2, TFDP1, DOCK1, TGFB3, PBX1, PAX2, DRD2, P4HB, TIE1, ANXA7, TIMP4, ANXA4, TK1, MTNR1B, COX1, PDHX, LGALS8, FES, XPO1, MXD1, TM4SF1, SH2D1A, LYN, LPP, FKBP1A, LPL, LIMS1, SLC30A1, LGALS3BP, ALPP, AFF3, LAD1, PAX8, KRT7, TFEB, SEM1, KIR3DL1, AP2A1, FRK, PSCA, FRZB, FECH, FCGR3B, FCGR2A, MAS1, TTN, MPST, MOS, EPHA4, TYRP1, EPHB1, AFDN, ALDH2, UBE2V1, UBE3A, MEOX1, SUMO1, UGT1A, AIF1, ETV5, EXTL3, USF1, MDK, F8, MCM7, MC4R, TRPV1, VRK1, DCC, PLAUR, TAP1, BHMT, SEMA3F, RORC, SELENOP, RNH1, RNF5, BMPR1B, BMPR1A, RNF2, FOXN3, SGCG, RGS4, RFC2, DAB2, BCYRN1, SIAH1, ST6GAL1, RELB, REG1A, SKI, RBBP6, CCR4, SLC2A3, ACKR2, SLC3A2, RPA1, RPA2, SDHB, CDK11B, SALL1, CASP2, CASP10, CBFA2T3, S100A11, SORT1, SLC25A20, CCL1, CD1D, CCL4, RPS6KA2, RPN2, PTTG1IP, C5AR1, CD28, C5, CCL19, TNFRSF8, XCL1, CD38, RPL17, C1QA, CD70, BCAT1, RAN, SLC12A3, HTRA1, RELN, PROX1, SQLE, ARSA, SRF, CTBP2, CTH, SRGN, PPP2R2B, ST13, ARHGAP1, PPP2R1B, PPP1R8, CYP2A6, TRIM23, PODXL, ABCC8, SUV39H1, PMAIP1, CYP26A1, AQP1, SYP, TAL1, KLK7, PSAP, COL5A1, CSH2, RAD9A, RAB5A, ATP7A, RAB1A, PYCR1, ALDH7A1, CP, SMARCE1, PTPRF, SMO, CPD, SNCB, PTPN9, CPT2, CR1, ATIC, PTGIS, PTGFR, PSMD4, SOD3, SOX5, CRKL, CRY1, KCNH2, CAPN1, SEMA7A, HMGN2, HLA-B, ADA, ACTG2, IGSF1, ACR, FFAR1, ADAM8, PARP4, GTF2H4, HNRNPU, GEM, IFI16, HMGB2, HMGB3, OGT, PIAS1, IRF5, STK24, GSTZ1, GATD3A, GBP2, CDC7, GCG, GATA1, GNB3, GDF1, ACTG1, IDH2, HDC, HSD3B1, IRF3, HTT, SLC7A5, IFIT3, USP11, HOXC10, GLB1, ING2, IL5, HOXA@, HNRNPC, BRF1, PPFIA1, GUSB, MAD1L1, GYPA, KAT2A, ITPR3, GLI3, FTH1, IL9, ITGB6, GSTA2, AXIN1, ACP3, AANAT, HOXC11, IL13RA2, HSPD1, PDE5A, RBM10, GTF3A, IL3, GPD1, MAPK11, HCAR1, MAPK6, CST1, PRAC2, CSRP2, PALD1, CSTA, WLS, PDE7B, LINC01193, TUBA4B, HCN1, SKA2, FOXD2-AS1, DKK2, STEAP1, DNAJC3, KDM2B, TAS2R38, CCL4L1, GLYR1, PSMD3, FBXO10, FBXO5, ERAL1, HOXA7, PSMC3, CRIP2, HOXA11, LHX6, PREX2, HOXB@, AATF, SIGLEC7, CSHL1, CKAP2, HAVCR1, CSN1S1, SPSB1, HBP1, LINC01116, HOXB3, CSNK2A1, HOXB5, NPTN, MLH3, PIF1, NCR3LG1, SOX2-OT, FSHR, LSM1, PADI1, DOK7, UBQLN1, A1CF, RGMB, HSPA9, PLCB2, DAPK3, PLCG2, DBT, DAG1, SCAI, RMC1, PLD1, E2F8, LIN9, PLEK, PLAGL1, ZNF326, HSPA2, FBXL19-AS1, BCL9L, CENPU, AKR1C1, PGC, FGF14-AS2, GLP1R, PGP, GLUD1, PKD2, MIR22HG, CXCL17, KLK9, DCK, ADGRE2, GLUL, RSPO1, ICOS, FXYD3, PDLIM3, GOLGA2, PPP1R2, HPRT1, SLC27A6, DCPS, CYC1, HPD, PPP2R2A, CYBA, PPM1B, ABCB5, HTRA2, CPP, PRCP, PREP, BMP10, CRCP, LINC01139, PPIB, POTED, GNAS, PLP2, GNA11, PARVB, PLXNA1, SEPTIN4, GNA12, KDM8, POLE, PPBP, FHOD1, POR, DNAJC15, DROSHA, PIP4K2C, CLEC4D, LINC00339, PHF5A, SMIM10L2A, KLK13, MIR199A1, KIF18A, GTF2H2, USP22, MIR196A1, SIN3B, CDC6, MIR198, MIR199A2, CDKN2D, RPL10, HCLS1, ANKRD12, CD81, HBB, CD69, HAS1, RORB, CDR1, CEP70, SIRT5, CHI3L2, ING5, CHD4, RIEG2, MIR15B, PDIA3, SIRT4, GSPT1, MIR187, MINDY4, MIR181A2, RAB1B, CENPA, MIR184, LOXL4, MIR186, ASCC2, AIF1L, HABP2, CBS, PHF8, CCNG2, CCNG1, H1-0, CCNF, ITCH, CCNC, S100A10, MIR208A, ROPN1L, EMILIN2, MIR30D, SARS1, CAST, PALLD, MIR32, KDM6B, CCT6A, SEPTIN6, MPRIP, FBXO28, FAM107B, SULF1, KAT8, SESN2, RHNO1, ACSBG1, CD6, KANK1, FERMT3, RCOR1, MIR219A1, CRISPLD2, TLCD3B, RPS15A, AKT1S1, CHIT1, RFX1, PGLS, POC1A, NECTIN1, MAK16, BACE2, GPR39, MTO1, RAB2A, RAD54B, RAD23B, WNT5B, RAD17, PANX1, ZBP1, KIF4A, BRD1, FLRT2, MR1, RCHY1, SOSTDC1, PTPN23, PTH1R, PTPN3, ATRNL1, TNKS2, HNRNPA2B1, CSAG3, TENM4, TIPARP, USP17L9P, KANK2, PNKD, AKR1C2, HNMT, AFAP1L2, CPA1, MIRLET7E, COL4A2, RFC3, SUZ12, PSD4, DNPEP, RBFOX2, RBL2, RBM4, SRRM2, RBP2, MNX1, PLPP5, SNX27, FAM83D, ANP32E, CBX7, REV3L, ELOF1, CHRNA4, MIR130B, GRB14, MIR129-2, DDAH1, HLA-DQA1, MIRLET7I, SMPX, RAP1GDS1, LCOR, PLA2G15, CNR1, SNHG1, CMKLR1, GRK5, RARRES2, RASA2, DDX58, BRSK1, TRIM11, PFN2, CYB5R3, TMED5, ZNF395, INS, TSHZ2, FBN1, FBRS, CMPK2, RBM45, ACSL1, NSD1, F10, PCDHGB7, ALG1, MCM6, F9, ARHGAP9, F7, CPEB2, ACSS2, METTL3, LTB4R2, CCL28, PNO1, MAGEA2, GARS1, LXN, TINAGL1, SMARCAD1, TNFAIP8L1, SEMA4A, OSCP1, IQGAP3, MAN1A1, ROBO3, WDR20, LINC00628, TSACC, BCCIP, DIABLO, UNC45A, GAS6, PFKM, ECHDC1, MGAT5, IL16, ERG, DOCK11, S100A16, MIP, EPS15, DYNLL2, MAP3K9, DEPDC1, MAP3K10, ASAP3, MAP3K11, IL15RA, UBE2Q1, CHRNA9, ILRUN, ATF7IP, MGAT3, TNFRSF9, ILF3, ANKRD44, MAP3K3, GBP1, MAP3K5, ST6GALNAC1, ETV1, ETFA, CMTR2, MEST, TDP1, PRR11, ETF1, PDIA2, OGDHL, AGK, CCAR1, TMEM88, SMYD2, MEPE, FGF5, FOSL2, ITGB5, KIF11, FMOD, MYOCD, MIR155HG, PHRF1, CARD16, USP28, KRT6A, ITGA4, STIM2, KRT13, CFAP97, L1CAM, SRR, SMYD4, LACTB, KNG1, UCN3, FUT1, EGLN3, ACE2, IL21, KCNN3, SLC25A19, FRA16D, PRUNE1, KIF2A, KIR3DL2, FRA7G, NGB, PTBP2, CYP4F11, MARK4, FOXP2, KIR2DS1, PIEZO2, ITGA2B, RPTOR, LY6E, FH, FGR, LTB, LRRK2, LTBP3, H4-16, BCAM, PDXP, PDX1, TIMM50, INSRR, ADAMTS9, TPPP2, IFI6, TC2N, PAQR4, LRP5, ACKR1, ARHGAP31, TENM2, LAMC2, ARL11, KIDINS220, LCN1, FOXJ1, FUT8, LGALS4, IRF7, LOXL1, LGALS9, LIG3, PBXIP1, UBE2Q2, VANGL2, EIF3H, VWA5A, ENGASE, E2F7, MNT, EPB41L4A-DT, PTRH2, OLR1, GFAP, GFPT1, CT83, BRCC3, SLC36A1, TSPYL5, NOX5, OXA1L, PAGR1, PAM, NCKIPSD, ID4, NOP16, ISYNA1, NKD1, DERL1, HBEGF, OAS3, SYNPO2, CITED4, CHAC1, TERF2IP, NPPA, DDX53, LINC00160, DUSP6, ADAM22, CMPK1, SPA17, DUSP2, MAP3K20, NTS, MAPKAP1, TMEM8B, CADM4, MRPL58, PRRX2, ADGRF5, ARHGAP10, NUSAP1, CPA4, PDC, PCSK9, HRH4, SLC26A4, RHBDF2, MLXIPL, TFDP3, GAL, NDUFA13, MEMO1, MAGEA2B, ISOC1, DHX9, DDX1, RICTOR, GOLM1, PCDH7, HOXA11-AS, KDM1B, SERPINA5, ATRAID, POMP, LINC00518, CHST15, PCP4, GJA3, HTR2A, FZR1, TNFAIP8L2, GJA8, TLR8, SPDYA, PDB1, DNAH8, FGD3, NNMT, SMPD3, NMT1, TBL1Y, APPL2, MUC6, LINC00473, IL4R, CASD1, MCU, MSTO1, MYCL, MYH2, MRPL41, MYH10, MYH11, FANCL, PRPF38B, ELF1, IL2RB, IL7R, EMP2, ASXL2, MSX1, MPG, HES6, ZNF331, MCM10, MPZ, CITED1, MSRA, SYNJ2BP, MTHFD1, CERK, DRAM1, MSX2, MTAP, ATP8, P2RY12, NUDT1, SERPINB1, GPAT2, GPBAR1, EFNA2, NEDD8, ZBTB10, PEBP4, NEO1, ERCC6L, RHPN1-AS1, PPP1R12C, EEF1A1, FNBP1L, SLC5A8, NFYA, SLC25A21, DNAAF4, ECHS1, NNAT, UGT1A8, PGPEP1, CELSR2, LAMTOR1, EGR3, RBPJ, TESC, CAPN2, NAIP, NAP1L1, IGKC, ODAM, SARS2, SEPTIN2, PAQR3, MLIP, KLB, NDN, FAM53A, NDUFB3, SLC2A12, VAMP8, PTGDS, SLC14A2, MIR1301, HIF1A-AS2, PDLIM1, ATP6AP2, PDZK1IP1, AFM, SSTR5, SSTR1, SSRP1, ARHGDIB, SMIM10L2B, WNT11, MIR1290, TNFSF13B, AIFM1, SSAV1, TNFAIP3, CTR9, CRNDE, USP39, NRG3, ARNT, USP8, CERNA2, ARRB1, ARRB2, ANG, H3P12, LPAR6, NME1-NME2, ARID3B, OSMR, ARF3, MYOM2, HEXIM1, TMPO, COX7A2L, PCSK7, RBM5, RBCK1, MIR4732, TKTL1, EPX, TRIM16, CELF2, ZFX, SULT1A2, AURKC, ZNF197, H4C9, STK3, STAT2, STAR, LINC00598, ADRA2A, ACOX2, LINC00461, PLK4, WNT3, SIX2, MIR454, SOX11, BIN1, SPAG9, MIR500A, SOX3, WIPF1, MIR668, HCP5, ASPH, PKD2L1, ARPC2, LSINCT5, SNTA1, RAI2, MIR520C, BLACAT1, TSPAN1, MIR1204, PRNCR1, ATHS, HAP1, MALT1, MIR498, ATOX1, ARPC1B, CERT1, TPD52L2, FRY, AGTR2, SPAM1, RAI1, H4C4, CLIP2, CHL1, GIPC1, SPRR2A, H4C6, H4C12, TNP1, H4C11, CAPG, H4C3, APOBEC3A_B, NBAT1, OPTN, LINC01133, CCR9, TRAP1, ANCR, H4C2, STARD10, H4C5, H4C13, MIR505, H4C14, DVL1P1, SULT2A1, BLCAP, TLE1, PEMT, KAT6A, PIAS3, TFAP2B, RECQL4, EEF1E1, RECQL5, VPS4B, GOSR1, LIPG, BRD3, ZFYVE9, NCOA4, RACK1, IFITM3, RAPGEF3, LINC00673, SSX2B, SLC25A16, RBM14, MAP3K12, LONP1, FAM3C, TMBIM6, ADAMTS9-AS2, TEAD4, SELENOF, TFCP2, MIR539, LUCAT1, MAEA, ATG5, MIR652, DLEU1, ST8SIA4, KLF10, SLC39A7, AP2B1, MAFK, THBS2, TLR6, APBB1, KLF2, MIR3646, MICU1, TGFBR3, NKX2-1, NTN1, TUSC3, AIRE, TUBB4B, TKT, SYCP2, DNALI1, CNKSR1, NOD1, NBR2, SLC9A3R2, MAD2L2, MIA, TBXA2R, MIR4728, P3H3, DLG5, DLGAP1, CDR3, GLRX3, KIR2DS2, TARBP2, PRDX4, ARL6IP5, TAP2, APOD, PIBF1, SLC19A2, MIR411, DCLK1, OLFM4, AKAP3, RBM39, CCT4, CCT2, SLC33A1, KIF20B, AQP4, H3P41, NOG, HYOU1, ZNF32, ZNF35, MIR597, EI24, MIR592, TADA3, NXF1, GRK2, TRIP13, TCF21, LINC00968, RBM14-RBM4, RPL17-C18orf32, ADRB3, MIR574, ADRB1, TCL1A, CCL4L2, ZNF143, MIR569, TCF7, MIR568, FBLN5, ELOC, APOC3, EIF1, GDF3, SNCA, H4C8, ACYP2, ACP1, MIR874, API5, LOC100288966, FGF19, UPP1, HPS5, MIR346, SELENOW, SIRT1-AS, ACP5, BNIP3L, KHSRP, SLC23A2, MIR422A, MIR331, TUBG1, SEL1L, ALOX15, TUFT1, SOX2-SRR2, LINP1, MIR328, KLF9, TUSC2, CBX3, UGT2B4, KLK8, TUB, UTS2, HCAR3, MIR384, TOX, LINC01857, BVES, PARG, RASSF2, CORO1A, PMEL, ACTN1, PTBP3, NUDT5, IKBKG, IFITM1, SHMT2, BDKRB1, CFB, HNRNPDL, SH3GL1, THOC1, IRAIN, GACAT3, CBX4, MIR543, MIR937, POLI, GABARAP, UGDH, MGLL, CCL7, UBC, TNFSF9, LNCRNA-ATB, SRL, TNFSF12, TNFSF12-TNFSF13, MAPRE1, PLA2R1, H3P7, GPAA1, SNW1, UBE2B, KIN, H3P24, AGAP2-AS1, H3P42, PTGR1, S1PR4, UBE2E2, H3P47, MIR9-1, ALDH3A1, CAMK2B, NINL, CANX, CA5A, MAPT-AS1, MIR302B, MORC2, SPATA2, MIR151A, TYR, SDC4, SDC2, CX3CL1, EGOT, TYRO3, C3, ACLY, MANCR, ZNF652, CCL25, IQSEC1, PLPP1, CCL16, USO1, DLK1, ST8SIA6-AS1, FADD, RIPK2, MIR2052HG, HSD17B6, CA1, GINS1, SIX3, THPO, SART3, MIR888, MIR675, AK6, MIR511, SLC7A1, H4C15, ATP2B4, VGF, ATP2B3, CACNA1H, CNMD, SMARCA5, CBX1, CACNA1I, MIR765, AMD1, PRDX3, TOPBP1, BCL2L10, MORF4L1, DNAJB4, MIR362, VTRNA2-1, MIR665, MIR1247, MIR410, AMHR2, IATPR, BTRC, RANBP9, AZU1, HSP90B2P, ATP6V1C1, FAF1, KIAA0100, PARP2, SMARCA1, MIR433, BCL10, SLCO2A1, SLC25A1, MIR491, MIR18B, TRPM2-AS, BAAT, TRPC3, ZGLP1, ATP2A2, MIR1307, MIR301B, SELENBP1, EHMT2, LIMD1, ATP1B2, RAE1, USP1, MIR4435-2HG, MIR873, RCAN3, CAVIN2, CSAG2, ABI1, SLC2A4, GHET1, TPM2, SMS, SMPD2, SETD1A, TRPM2, ACTRT1, MIR1229, TAF8, MIR1266, MIR3666, LRG1, MIR3908, MIR3617, F11, TGM7, CNTROB, TOP1MT, MIR1207, PNCK, FANCB, FAH, ZFHX4-AS1, FOXL1, FANCE, MIR3942, MIR1256, GRIN3B, MLANA, MIR1296, ZNF501, ATG4A, AD11, FOXS1, ALAD, TNFRSF13C, MIR3609, MIR3614, FLG, FUNDC1, UPRT, DBH-AS1, ERV3-1, MIR3922, FBN2, PIGU, MIR3923, MIR1297, UHRF2, FBXO32, MIR1228, FLII, JMJD7, OMA1, FOXE1, BHLHE23, WDR92, AHCY, AK4, PIFO, VASN, MAGEE2, AFA1, MIR374C, H3P20, UHMK1, FOXD1, CPT1C, MIR548J, MIR1471, FGA, AEBP1, EVI2B, TDRD9, LOC100422227, SPPL3, MIR1267, MIR3196, MIR1915, MIR1469, MIR1236, MIR3188, TDRD10, NCOA7, MIR1179, HMGB4, MIR761, TSPY10, MIR2276, FGF9, EMB, USP43, ZEB2-AS1, TMEM132E, MIR663B, F2RL2, EZH1, CYB5D2, MIR762, GNG12-AS1, MIR1284, FGD1, EXT1, TBC1D16, TMEM219, EWSR1, SETD9, MTPN, LOXL1-AS1, MIR1193, GOLT1A, LINC00899, FKBP1AP1, AHSG, MIR1972-2, MIR3141, MIR4262, MIR3184, FKBP1AP2, MIR4282, FCER1A, MIR1249, PXDNL, FKBP1AP3, FKBP1AP4, CD200R1, FOXG1, THEM4, ANTXR2, MIR3065, ALKBH2, MIR1245A, ETV3, FGD4, VPS37A, MIR4293, MIR1287, FGL1, MEF2B, MIR4316, MIR664A, SFR1, FCGR1B, MIR4301, MMP21, FHL1, FHL3, EXOSC6, MIR3200, FOXN4, MIR33A, RHPN1, KLHL22, C3orf67-AS1, MIR503HG, ZNF496, ABHD14B, PLCD4, ADAMTS9-AS1, ODC1-DT, GPAT3, LINC01585, LOC101930370, KMT5C, GOT1, SPSB2, GPLD1, GPM6B, GPT2, LOXL3, MIR6826, CCDC54, PPP1R9B, CCR10, SLC9A7, MIR6861, MIR6882, TRIM63, MIR8073, MIR7847, USP32, MIR6875, ZNF503, RIOX2, COMETT, GOLGA1, FOXD3-AS1, RGS8, GHRHR, GIP, LINC01355, NPY4R2, GLA, MYLK2, ALG2, KRT90P, ADH5, PLIN2, SNHG12, FAM83A, EZR-AS1, ADCYAP1R1, ATG4D, ADARB1, GM2A, MAEL, ATG4C, PPP1R15B, GNAQ, FBH1, LINC01483, LINC01787, GNB1, ACVRL1, PTPN5, MIR8084, XCR1, ROCR, USP38, GSR, SNORD138, GSTM4, TMEM126A, TRAF7, GSTM5, LOC110283621, LOC110599580, ACAT2, ACADSB, BTG3-AS1, ABR, KIAA1109, RNASEH2C, SIRLNT, ABL2, GTF2I, ABCB7, AARS1, AAMP, USP44, H3P28, RAB6C, GUCY1B1, MAGT1, AADAC, H3P33, GYPB, CCDC8, HSDL2, TALAM1, GRM4, GRK4, GPR17, LOC102723971, ACVR2B, LNCTAM34A, GPR19, ACVR2A, ST6GAL2, SLC12A8, MAP1LC3A, GPR35, LINC01287, FOXC2-AS1, MCM8, PERCC1, GRIN1, LOC105371849, MAP3K21, SYVN1, MKNK2, GPT, ACTC1, GPX7, LINC01614, LOC105377871, ACTA1, LOC108004545, HVCN1, SARNP, NKD2, B4GALT1, FLT3, CENPI, MIR497HG, BIRC8, GAS1RR, TUNAR, CCAT1, FTH1P3, FTL, ABCC12, FUCA1, ORMDL3, LINC00707, SFXN1, FUT2, CT47A12, SNHG16, ARHGAP18, C8orf17, FUT3, LINC00458, FUT6, PGAP3, LINC01016, LY75-CD302, ZNF276, MAFG-DT, BCL2L2-PABPN1, RAB4B-EGLN2, ATXN3L, SPECC1, CAVIN3, MRPS30-DT, DCLK3, IL17F, CCDC85A, RAD51-AS1, UBE2Q2L, ITGB2-AS1, PSMG3-AS1, FLT3LG, LINC02582, FMO5, MAL2, AP2A2, LOC100505909, LINC00963, HOTAIRM1, GAS6-DT, CBR3-AS1, LINC00310, SLC35A4, FPR1, PIK3IP1, FRA6E, LIFR-AS1, CYP2U1, CMTM1, GRK3, TMEM54, FRA7H, KIF12, CDCA5, MTFR2, FYB1, ADRA2C, BIVM-ERCC5, GABRA3, GCSH, ADRA1D, NNT-AS1, GCY, ADORA2B, DUOXA1, MIR5188, BMF, HEIH, MSTN, UNC5A, CERS6-AS1, KCNH7, FSBP, WDR34, CYP3A7-CYP3A51P, AQP10, SEC16B, ERVK-11, ABCC10, NAV1, MYB-AS1, STARD13-AS, HOXC-AS3, HOXC13-AS, ADORA1, IFNG-AS1, SCIN, GFM1, ERVK-22, ERVK-15, ERVK-12, MIR4480, GAD2, TMEM132C, GALNS, ERVK-2, LRRC32, MIR4469, ZNF300, CHRDL1, MIR4428, GAS1, MIR4458, GAS8, SLFN11, DERL3, CARMIL3, GATA6, BOD1, MIR4530, L3MBTL4, MIR4513, MIR4485, GBX2, MIR4766, MIR4665, MIR4484, JPT2, MIR4443, GCNT2, GPR119, FEZF1-AS1, MUC17, NPS, CSNK2A2, ASCL2, HCC, MBOAT4, LINC00589, KLKP1, HAS2-AS1, HDDC3, ENHO, MIR510, SLC27A1, MIR509-1, CA13, MIR507, ASCL1, ARSF, RBMY1D, CSTF1, RBMY2DP, SLC35B2, ARL2, AMIGO2, ARPIN, BCRP1, ARSD, ASPG, NUP43, ZACN, RGSL1, MIR487A, DND1, CSNK2B, ASIP, HMGA1P7, MIR567, LRRC26, PCARE, TSPYL6, MUSTN1, CPM, MIR496, ATP1B1, C1QL3, MIR99AHG, MIR432, BRCA1P1, ATP2B1, CPB1, FENDRR, COX6C, LRRC75B, HRNR, SNHG5, SERPINA13P, ASNS, ASPA, CRIP1, C10orf143, C12orf75, CREM, MIR520G, CRABP1, RTL1, TNFAIP8L3, ASS1, CRAT, IMMP2L, YPEL2, IGFBPL1, CTNNA1, ARHGDIG, AQP7, DAB1, MIR33B, SNORA7B, CELIAC2, CHSY3, CYP11B1, CYP4B1, TRARG1, CYP2J2, PAX8-AS1, CYP2D7, AQP9, S100A7A, ASAH2B, EIF4E3, DGKA, ZFP57, MIR553, STPG4, MIR562, EPHA6, SUMF1, CTBP1-AS, MIR559, LINC00491, MIR449B, MROCKI, MIR552, DAZ1, SNHG15, DLX6-AS1, MIR551A, CT47A7, ARF4, IFNE, CX3CR1, VSIG1, SIAH1P1, NANOS1, NEK5, CYB5A, STAC2, CTSZ, HSR, RSPO4, TMPRSS7, CTSG, CTRL, RASSF10, CTNND2, ARHGAP5, RSPO2, TSPAN33, LINC00520, ARSI, CYLC2, RHOB, LINC00273, C3orf35, ARMH1, CLEC4G, CYP2A7, LINC01089, CYP3A7, HCAR2, SCFV, CYP2C18, COX5B, LINC00668, COX4I1, ADGRE5, CDH4, CDC25B, MIR197, BTF3, SEPTIN7, CDC5L, BYSL, CDH15, ENTPD5, ENTPD3, BPY2C, BPY2B, C4BPA, CD86, BTD, CDH17, CHD1, CETP, MIR16-1, CEACAM8, MIR196B, BMP5, BMP8B, MIR367, CENPE, BTC, CEL, BNIP1, CLGN, BOK, BPHL, ZFP36L2, CD27, GAS8-AS1, CD22, RUNX1T1, MIR95, MIR28, CALML3, CBR3, SERPINH1, CBL, MIR92A2, CD8A, CASP6, CASP5, CASP1, CALU, CAMLG, CAPNS1, CCKBR, CALD1, CAD, CACNA1E, MIR24-1, CCT, CD1A, CA11, PIM3, CD3D, SMIM22, CD3E, MAP1LC3C, MIR218-2, MIR217, CD5L, NRARP, TARP, CHD3, HAGLR, BCAT2, MIR363, MIRLET7D, PGM5-AS1, MIRLET7F1, ANKRD30BL, BAGE, BCL2L1, MIRLET7A2, COL4A1, MIR101-1, CNTN1, CNP, KIR2DL5B, PLK3, COL4A5, HNP1, AKR1C4, CUEDC1, CORT, MIR488, CASC15, KPNA7, IFITM10, COL15A1, LINC01561, MIRLET7A1, MIR376B, ATRX, KIF1A, COL12A1, COL10A1, ANKHD1-EIF4EBP3, CNGB1, LTB4R, MIR124-2, CHM, CIRBP, BCR, CKB, BDH1, MIR377, CHRNA5, EID3, ATXN7L3B, SUMO1P3, BNC1, MIR147A, CHGB, CHGA, POTEE, CKS2, CLCA1, CLK2, CLN3, MIR133A1, TNFRSF17, CLTA, BCL9, CLTC, BCL7A, MIR128-2, BCL2L2, CCR3, ANIB3, DUXAP9, MIR125B1, CT45A1, MIF-AS1, RUSC1-AS1, ASB6, TMTC3, MOSPD2, RHOXF1, USP51, USP17L30, SLC35G1, EDN3, S1PR3, MEMO1P1, CLEC14A, EDA, SPRED1, USP17L29, SLFN5, FBXO39, C2orf92, SHOC1, USP17L28, IQUB, TBC1D3, DAB2IP, IRX2, PRSS3P2, AMOTL1, OIP5-AS1, TEX46, EFNA3, UNC5B-AS1, SPANXB1, ANKRD46, HULC, LRATD2, LINGO2, PLPPR5, CALML6, LOC284454, CT47A1, MIER3, DUSP8, DUSP7, BHLHA15, HTR3C, TSPY3, PSORS1C2, LINC00460, ADAMTS17, ADAMTS18, DUSP5, ASXL1, CT47A2, DNAJB1P1, SGMS2, RASSF6, IFNLR1, HFM1, USP17L27, ECE1, USP17L26, ANK3, USP17L25, USP17L24, CCDC116, MAGED4, E2F6, WBP2NL, DEFA1B, DYRK1A, CARMN, DUSP9, MEGF9, EIF2S1, BTLA, EPB41, MIR939, KRT80, MIR933, EPB41L2, A2ML1, FBXL14, SLC38A6, OR2AG1, ALPI, ENSA, ALPL, MIR942, ENO2, ALX3, MIR365A, TTC36, EIF2B1, NRSN1, FOXO6, RAB6C-AS1, GATA5, ALDH1B1, EPRS1, TFAP2A-AS1, FGF13-AS1, ALOX5AP, SRXN1, SIRPA, MIB2, EPHB3, ABCD2, MUC15, HAPLN3, MIR934, NRG4, EIF4G2, AMELX, TMEM170B, PYHIN1, SHLD1, SIK1, AIFM3, AMPD1, EN2, LINC00309, EIF4B, PSS, MIR802, MIR766, EIF2S3, ELF4, MIR298, AMD1P2, HJV, MIR450B, ELK4, CREB3L4, EMD, SPC24, TMC4, APCDD1, AMBP, SLC25A52, CCBE1, TMEM199, EMP3, IL34, CT47A3, AGO3, AGO4, DLAT, PROSER2, OR2T6, DLG3, ANKK1, CT47A11, MIR612, DHPS, DLX2, DHODH, GPX6, BIRC3, FAM133B, DFFB, APOA4, RNF169, MIR613, FOXK1, RNASEH1, SRRM3, TRDMT1, FAM83B, MAPK15, MIR616, DNM2, NEIL2, BRWD3, DNA2, DNM1, MMS22L, DLX5, MSRB3, YTHDF3, ASPM, MIR603, DFFA, DCX, CASC22, MIR588, MIR584, MIR578, NEK8, MIR577, DCTD, MAGI3, MIR573, ZNF763, WDR62, ZFP82, MIR7-3HG, SLC25A41, DDC, LINC00641, MIR589, MUC19, RASSF3, APOC1P1, MIR591, OR10A4, MIR593, MIR599, MIR600, DEFA1, HCA1, NPAS4, MIR601, HS6ST3, STEAP2, THSD7A, MIR621, PLPP4, FLCN, CRTC2, DSPP, TET3, PIKFYVE, TMEM17, ARL13B, SNORD118, LINC00466, RDM1, DSG3, HTRA4, DSC2, SLC25A6, DSC1, SLC26A2, SLC25A4, DOCK3, CT47A6, IMMP1L, RILPL2, CT47A4, CT47A5, METTL7B, RMST, PAOX, CT47A10, CT47A8, CT47A9, ADCY4, CT62, MLKL, GGN, DRD5, TMEM26, DRD4, DPYSL2, ALKBH3, MIR92B, SKA3, MIR645, ZUP1, OPN5, APAF1, TBATA, DPYS, DPT, MIR628, MIR627, DOK1, MIR622, MIR650, DPYSL3, SLC26A3, FAM171A1, UCMA, JMJD1C, DRD1, HEPACAM, OTUD1, MIR653, DOK6, LRTOMT, DDIAS, DRD3, SLC37A2, ANXA13, HYLS1, SLC4A11, LMNB1, TATDN1, CD160, PLAAT3, HHLA2, ST3GAL3, SHOX2, STRAP, ADAMTS6, FBXW4, MAP4K1, SH3GL2, ITSN1, SGTA, SFTPD, SFTPC, TRA2B, AKAP10, SRSF6, DUSP10, SRSF5, SRSF2, ZWINT, SLC1A2, SLC38A3, CIT, SLC27A4, SLC27A2, SLC18A1, SLC16A2, SLC11A1, SLC8A1, SLC7A2, TENT4A, SLC6A6, SLC5A2, CPSF6, SLC5A1, SLC4A1, SLC3A1, SPACA9, ADAMTS8, ADAMTS5, PRSS23, KRR1, RASSF8, PDCD10, ZHX1, SLC6A14, CCL14, CCL11, ANKRD6, CARD8, SACM1L, FAN1, CCL3, NCBP2, ATF6, SEPHS2, SCNN1A, SCAP, SCN4B, SCN3A, TRIM32, SCN2A, PAXIP1, NT5C2, SCN1B, INPP5F, DZIP1, FASTKD2, SDHA, HRH3, XPOT, NRM, USP18, TREX1, SEC14L1, ECD, SEA, SYNPO, CNKSR2, SDF2, CLCA4, IKZF3, IKZF2, ATF5, PUF60, CHSY1, CILK1, SDS, IMMT, GREM1, PAICS, STX3, TRIM3, STX1A, STK4, NPRL2, CAMKK2, YKT6, SPINT2, KHDRBS3, ST2, CD226, CGRRF1, SSR1, GNA13, DLL3, RO60, SRMS, SRI, SLC12A7, STYX, PAIP1, SLC22A1, CDC42EP3, APPBP2, HNF1A, TCEA3, DDX17, TCEA2, TCEA1, TBX5, TBP, TBL1X, TALDO1, IFI44, TAF7, SYN1, VAMP7, NPC2, GNLY, VAMP1, PRPF8, SULT1C2, OGA, NFAT5, SRD5A1, YME1L1, SNRPN, SNRPD1, CPSF4, JTB, GADD45G, EDAR, COPS8, SNAPC1, SIGLEC1, SMN2, TMED2, SMN1, SMARCC1, SMARCB1, EBNA1BP2, SLIT3, SLC22A5, COPS6, KCNQ1OT1, WDR3, C1QL1, SORD, CYSLTR1, MAP3K2, SPRR1A, PLK2, ZMYND11, ARPP21, NEK6, NCKAP1, SPOCK1, SPN, ME3, GJB6, HSPH1, SPINK1, FRS2, ALDH1L1, CD3EAP, SOX12, RUVBL2, ATXN8OS, CEP131, ATXN7, SLC7A11, RAP2A, RAP1B, PRKD3, RAG2, PPIL2, ARHGAP8, IFIT5, SHC2, RASGRP3, RAB5B, BRI3, RAB3A, TNFAIP8, TXN2, PYGM, POU2F3, PYGB, ASF1A, ARMC8, CEMIP2, RAP2B, ATXN1, EDC4, RBMY1A1, CABIN1, RBMS2, NNT, MMD, ATP6V0A2, TSPAN12, RBL1, PADI4, PRG1, CASP14, ARID4A, FAM215A, RARRES1, PHLDA3, RARS1, RUSC1, CBLC, RAPSN, PRKD2, RAD1, PAMR1, PTPRN2, PTGER3, PTGER2, PSMD7, SPAG8, PTTG3P, FBXW8, PSMD2, PLA2G2D, PSMD1, FGF21, EHF, PSMB9, PYY, PSMB8, PSMB7, PSMB5, PSMB4, PSEN1, RGS17, WSB1, TANC2, HERC4, VIRMA, TMEM158, PTPRM, PTPRK, ZDHHC5, CLIC4, PTPRG, NECTIN3, SYF2, EGFL6, RAI14, NGDN, L3MBTL1, RPAP1, PTMAP4, PTMA, TWF1, GIGYF2, PTK7, POFUT1, RENBP, ISCU, TMEM131L, RTN1, RTKN, ANKLE2, RPS27A, RPS19, RPS16, LPIN1, RFTN1, DIP2A, PHLDB1, CYFIP1, FBXL7, GSE1, ARL6IP1, MLC1, RPL36A, RPL39, RPL29, RPL24, RXRG, CUL9, RYR3, PDS5B, RAB21, SAT1, FAIM2, TSPAN31, USP33, SALL2, MYT1L, TNIK, ACSM3, KIF1B, ZHX3, VPS52, S100A12, CMTR1, HECW1, PEG10, S100A2, ARHGAP26, SIK2, PDS5A, TRAM1, RPL13, SRGAP2, RNU2-1, ECPAS, PIP5K1C, RNF6, RN7SL1, RMRP, ZFPM2, RHEB, TMED3, RYBP, GPR161, RHOQ, TARDBP, OTP, SF3B3, RHAG, RGS3, CBX6, PUM2, RNY1, ARHGEF12, MGRN1, MINAR1, OTUD3, DDHD2, CAMTA1, MCF2L, ADGRL2, ADGRL3, RPL7A, RPL5, ZNF629, NEMP1, DMXL2, DNAJC13, TUT4, NEDD4L, SYNM, ROM1, SUN1, SEMA4F, SEMA6B, TCF12, SCAF11, RASSF9, BUB3, CHAF1B, SLC16A7, GDF5, AKAP1, COIL, MSC, ST8SIA2, GCM2, GPR50, ANP32A, CACNA2D2, GPR68, DPF3, GPR55, S1PR2, CD83, CDK2AP1, ESS2, TMSB10, MACROH2A1, KDM5C, USP6, USP2, H2BC10, H2BC6, H2BC7, H2BC8, H2AC20, SLC16A6, FZD6, CNOT9, PRPF4, PRPF3, CCNB2, BRAP, ARHGEF1, ATG12, PDCD5, HGS, DYRK1B, COPS2, ALX1, TRIP4, AD5, SLBP, SEMA3B, SCLC1, KIF23, RPH3AL, ADAMTS4, ADAMTS3, ADAMTS2, LRP8, GAL3ST1, PTP4A1, MEMO1, SCAMP1, ZYX, TP53I11, ZNF236, IGDCC3, RAB3D, APBA3, PCYT1B, LAP, ITM2A, STOML1, CNOT8, RPL23, MLF2, LHX2, ITGBL1, CSRP3, RAB9A, NRXN3, LPXN, FZD3, TMPRSS11D, FADS2, CYP7B1, ST7, NCR2, MED23, MED7, ITM2B, H2BC21, DNAJA3, PKMYT1, HAT1, TMEFF1, CDKL1, PRKRA, PDLIM4, FGF17, CES2, MADD, YARS1, TCAP, GGH, CDC14A, AP3B1, PIR, BARX2, CAMK1, YBX3, AKAP4, ALDH1A2, GAS7, RGS20, NOP14, PLA2G4C, RNMT, EIF3G, EIF3D, GALNT4, B3GALT4, EIF3C, TRADD, TNFRSF25, EED, LAMTOR3, RUVBL1, ABCB11, KCNK5, AOC3, RTCA, UNC5C, TNFRSF14, PSMG1, RGS11, LDB1, MMP23A, BPY2, MMP23B, USP13, RASAL1, RPS6KA4, TNFSF18, LTBP4, SNHG3, SPARCL1, PLA2G10, CLIC3, BRSK2, PLA2G6, BAZ1B, CCRL2, TAAR5, DOK2, PIP5K1A, CLDN12, ASH2L, CLDN10, P4HA2, MGAM, KYNU, EIF2B5, PIK3R3, SGPL1, FUBP1, ZPR1, SLC5A6, GEMIN2, EIF2B4, EIF2B2, CPNE3, CUL4B, CDC42BPA, CCNA1, AP1S2, IRS4, CACNA1G, KLF11, MBD4, CUL2, ZNF224, VEZF1, TCF20, TNNC1, FAM13A, TNFAIP6, MBNL2, ABI2, TNFAIP2, WASF2, CLDN5, TMOD1, TSHZ1, ALG3, TSPAN8, MPHOSPH10, DHRS2, MPZL2, NR2E1, USPL1, SEC62, PSMD14, PRG4, CLEC3A, TNNT1, ZNF131, TOP2B, SH2D3C, DNAJB6, SMC4, UBA2, SAE1, TRAF3, TRAF1, IL18BP, DPP3, HUWE1, TPM3, GPC6, PPIF, TPH1, KIF20A, ACTR1B, RASGRP1, PDIA6, TOP3A, ANGPTL7, KLRG1, GDF11, TRIB1, IRF9, BTN3A3, CPQ, BASP1, TF, IFI30, TEP1, TEAD1, MERTK, TDGF1, ZNHIT1, TDG, TIMM44, TRBV20OR9-2, CAP2, TCN1, VAT1, STK25, ENOX2, TFE3, CACNG2, TRIM22, TJP1, TLN1, RASGRP2, TLE4, GPHN, RABEPK, SPRY2, STAM2, ZMPSTE24, STAG1, THBD, TIAL1, LILRB2, THOP1, APBB3, LANCL1, THBS4, SMYD5, TFG, TRO, TROAP, FRAT1, TM9SF4, CEP135, SAFB2, EIF5B, IPO13, VRK2, VGLL4, UBE3C, CROCC, CEP57, BEST1, USP6NL, NOS1AP, VLDLR, VIPR2, DOCK4, VCP, VCL, SLK, USH2A, ZNF516, SOCS5, MICAL2, NFE2L3, ZNF121, BABAM2, CDC42BPB, ZNF24, ZNF23, WTAP, CNBP, PITPNM1, CARTPT, WNT6, ZIC1, ZAP70, YWHAE, YES1, WNT9A, WNT7A, FEZ1, ZNF592, USF2, PIEZO1, SH2B3, UCK2, KBTBD11, PUM3, TNFSF4, HS3ST3B1, HS3ST3A1, USP3, TNFSF15, TTR, MED13, CCS, NR1D2, FGFBP1, TTF1, SLC12A6, TSTA3, EIPR1, TSPY1, TSHR, TRPC6, SEC16A, ARNT2, ATP2C2, PPP1R26, UMOD, IST1, UCHL3, ARHGEF11, TRIM14, UBE2V2, ZBTB24, HEPH, MAGI2, MRC2, TLK1, UBE2D3, TOX4, UBE2D2, RHOBTB1, NUAK1, FIG4, UBAP2L, MYEOV, PRSS8, EIF2A, LBP, LAMP2, HACE1, LAMP1, LAMB3, LAMA5, MICAL3, LAMA3, PCDH10, KIF17, KRT81, WDR48, TSHZ3, KIAA1522, KRT2, KRT1, EPB41L5, CHD8, KIF22, USP37, MAVS, NLGN4X, LRP2, LCP1, CORO1B, VARS2, SLC39A10, SELENON, FADS1, LIMK2, SENP7, ZNF304, TTYH1, RHOJ, LIG1, LHB, SPC25, SLC24A3, NDRG3, BIRC6, TBC1D24, GRAMD1B, LDHC, MIER1, KLC1, NCOA5, KIR2DL3, JUP, JAK3, ITPKA, ITIH4, C12orf10, EDA2R, ITIH2, HPSE2, IGAN1, ALX4, ITGAX, ITGAM, ITGA7, PROK2, ITGA1, CHP2, NECAB3, IRF4, TP53AIP1, SCPEP1, KCNA1, SIGIRR, CTDSP1, KIF5B, G6PC2, LSM2, CCDC181, KIF5A, MUC3B, RBPJP4, KIF3C, KCNN4, UBL5, TP53INP2, CREBZF, RPRD1B, OVOL2, OPRPN, SCAF1, KCNK1, HIVEP3, GJC2, RALGAPB, SNORD24, VPS11, SELENOS, CISD1, USE1, MEFV, MEF2A, RCC2, ADAM11, AJAP1, SLC50A1, KLHL7, MCM5, PCDHG@, PCDHB@, PCDHA@, TEX15, TEX14, RNF17, MC1R, MBD1, DCAF6, MAP3K4, LSS, DOK5, RABL6, MICB, VAC14, CCDC88A, IPO9, CD99, IQCC, ASF1B, HHAT, MGAT1, PARVA, MFAP4, INAVA, H2AJ, ZNF415, DEPDC1B, CSGALNACT1, CACNA2D3, FOXJ2, RNF20, CPXM1, MAX, PARD3, SMAD6, ENY2, SMAD5, RGMA, PARP6, NBR1, KIF15, CAPRIN1, CTNNBIP1, LYZ, CCNL1, LY75, LTBR, CYSLTR2, KMT5AP1, REXO4, CAMK1D, CD177, RTN4, DUSP22, ARNTL2, CA10, JPH1, SLC7A10, DNAJC12, MMP26, EIF5A2, MATN1, CLDND1, MATK, MAT1A, MAP2, MAGEA5, BARHL1, MAGEA12, BDH2, THAP10, MAP3K7CL, C1GALT1, NMUR2, PAK6, ERVK-6, PERP, CDH23, ALPK1, WDR26, HOXA6, CPEB4, ZKSCAN3, HNRNPF, COASY, HMGCS2, TSGA10, HMBS, ASXL3, EEPD1, DUSP16, KDM7A, HLA-E, HLA-DRB5, ILKAP, HLA-DRB3, HLA-DRA, HLA-DOB, HOXB1, HOXB2, PBLD, HKDC1, MAP9, HDAC11, GGNBP2, PRR5L, CYBRD1, SETD6, HOXD3, HOXD1, SCD5, CPED1, HOXC6, STN1, ESRP2, C10orf88, HOXC@, TRIM46, HOXB8, HOXB4, MUS81, ITFG1, SLC38A1, TMX1, GDPD5, PITPNM3, HELLS, NUF2, HARS1, HADHA, TEX101, PARP9, TRAPPC9, H2BC5, RIOK1, GZMM, MARVELD1, GUCY2D, ATAD3B, RAB34, TBC1D10A, GYPE, CDCA7, LRMDA, QTRT1, CFH, MED25, DOCK8, TDRD3, MAGED4B, TXNDC5, ACTL8, CDT1, DIAPH3, HK1, HIVEP2, PPP1R14C, CFHR1, ADAMTS12, TLR10, SLCO5A1, UBE2K, VANGL1, TRIM56, HIP1, SPRY4, CBLL1, CPSF7, CSPP1, IFNGR2, NUCKS1, ACBD3, ILF2, IL12B, DEPTOR, CYP3A43, FBXL17, NIBAN2, NABP1, PAPOLG, CENPH, PINK1, CDK15, IGHMBP2, IGHG3, IFNW1, ZFP69B, WNK2, DLK2, IMPDH1, GIGYF1, CPEB1, P3H1, MCCC2, PARVG, INPPL1, CENPK, RTP4, MAGEF1, SLC39A8, INPP5D, PDLIM2, IMPDH2, ARHGEF28, INHBB, SIL1, HHIP, CDH22, INCENP, DCLRE1C, ATG3, CUEDC2, IFNGR1, FAM124B, IFNAR1, FOXN2, NDST1, DNAJB1, RIOX1, HSPE1, MORC4, NPEPL1, TBL1XR1, HSP90AA2P, HSPA1A, RERGL, FBXO31, SHCBP1, HAND2-AS1, HRH1, ERAS, HPX, HPS1, AGBL2, HTN3, NLRX1, PPP1R3B, MMEL1, PVRIG, DDX54, IFN1@, CFI, FA2H, IDS, TMEM43, IRX3, IDH1, HTR1B, HMGN5, NKAP, ID2, ICAM4, CERS4, NAA16, IAPP, HUS1, NBPF1, RNF126, ATXN3, ABCB4, PGM3, DEF6, GEMIN4, ANO7, PGD, NEUROG3, PGAM1, TRAT1, HEBP1, PFKP, DERL2, PFKFB2, MRPS18C, PRLH, PFDN4, LAP3, RPS27L, APIP, TMX2, GALNT9, PHF2, ANAPC7, NOX3, OBP2A, ERO1A, PLA2G2A, PKLR, PKD3, SOX8, VSX1, PITX1, PIK3C3, SOCS7, EHD2, PIK3C2B, TAX1BP3, PIK3C2A, SERPINB9, RRM2B, SERPINA1, G0S2, PHKG2, PENK, CRYL1, PEG3, SH3GLB1, DNAJC27, TLR7, GMPR2, CD320, ZDHHC3, ARMCX1, SLC25A37, CDK18, PLAC8, SPG21, CDK16, DACT1, PCSK5, TAOK3, PCSK1, ZMYND10, PCNT, PRKAG2, POLK, PIPOX, NT5C3A, PHF20, LINC00328, PHF20L1, PDK4, PDHB, INSIG2, CHCHD2, PDGFB, PDE8A, SLC45A2, JPT1, CLDN18, EGFL7, DBR1, PDE4B, PDE4A, PDCD2, GPN3, NIN, ZDHHC2, SLC39A2, RHOD, NRBF2, DESI1, PKIB, GNMT, PRKACG, PRKACA, PCDH17, PRIM2, HPLH1, RND1, PRIM1, TNRC6A, PRB4, NPY4R, UBE2S, PPT1, PPP5C, PPP3R1, PCSK1N, PPP4C, STK39, PRKCE, PRKCH, INTU, MAP2K3, CHORDC1, PRSS3, CYFIP2, TPK1, PROC, ZBTB32, ACAD8, PRM1, LAMP3, CPNE7, MAPK13, MTBP, MAPK10, B3GAT1, PRKCSH, DKK4, PRKCQ, INPP5J, PPP2R5E, EML4, PLAGL2, SLCO4A1, PLXNA2, TMOD4, PLTP, CYP2S1, REPIN1, TRPM5, CNOT7, TRA2A, GPSM2, CCDC106, GPR132, DSE, PKN3, ANAPC4, DNMT3L, PLCB4, IL19, SLC25A24, PRICKLE4, PNMT, UBL3, PON2, NOB1, SLCO3A1, SLCO1B3, REM1, PPP2R1A, PPP2CA, PPP1R7, PPP1R3C, MAGEH1, NTMT1, CFAP20, PPP1CA, HIPK2, KLF15, PPID, NDUFAF4, PHPT1, PPAT, LGALSL, SNX9, SCARA3, BCAS4, NCAPG2, CDKAL1, NDUFB9, NDP, DUSP23, ADPRS, SOHLH2, SDHAF2, C1orf109, TIPIN, PIGX, NCAM2, TMEM70, MYO6, PIH1D1, CDCA4, TRMT12, SUSD4, MYO5A, MYO1D, NDUFS4, UHRF1BP1, PCBP1, ANKHD1, RRN3, MARCHF5, NFIL3, NFIC, NFIB, NFE2L1, ZRANB1, NFATC4, BTG4, NFATC1, MED18, TRIT1, DYM, GIPC2, NEFH, LRRC49, NEFM, GDPD2, ST7L, TMEM45A, ARGLU1, MYO1C, GPATCH2, MSH4, STYK1, PI4K2A, IMPACT, LGR4, LRRC59, BATF3, MNAT1, MMP12, PLXNA3, SUPT20H, TENT5A, OTUB1, MLN, PRR5, STAP2, THUMPD1, CHD7, SLC48A1, COX3, CASC1, MTM1, MAP1S, MYL4, ARHGAP17, MYH6, PNPO, MRPS18A, MMUT, MUC5AC, PLEKHG6, MUC3A, ND2, MTX1, ATAD3A, ND5, ND4, ND3, LRRC1, UBA6, OGFOD1, CRLS1, UGT1A4, PAF1, NUP88, LARP7, AZIN1, TRIM33, SIX6, EEF1AKNMT, PIGT, OPCML, CHMP3, RASD1, OGN, MPC1, OGDH, NLK, OAZ1, ACSL5, ZNF44, RAB23, RAPGEF6, GHRL, ORC4, OTX1, OTX2, REG3A, VGLL1, REV1, NAT8B, LIMA1, PARN, RTCB, TRIAP1, UFC1, ETV7, IL23A, DTL, TMEM14C, ANAPC11, PAH, P4HA1, P2RY6, OXT, RAB6B, NR4A2, RTEL1, CCNJ, ROR2, NPPB, PNP, SLC38A2, DNAJC10, SSH1, NOVA2, NOVA1, RIN2, TAF7L, CNOT3, DGCR8, NODAL, CCHCR1, EPB41L4B, UGT1A6, NKX3-1, LZTFL1, NID1, DDX56, NPR1, CYCS, NANS, BCO1, KDM3B, NTRK2, NTF4, IL17D, TM6SF1, LRP1B, NRL, STX18, PRKAG3, CHRAC1, NRDC, SLC11A2, IL20RA, FGFRL1, DUOX1, SLC37A1, SETD4, NPY5R, NRG2
    • Breast Cancer Mayo_clinic
      Overview Breast cancer is cancer that forms in the cells of the breasts. After skin cancer, breast cancer is the most common cancer diagnosed in women in the United States. Breast cancer can occur in both men and women, but it's far more common in women. Substantial support for breast cancer awareness and research funding has helped create advances in the diagnosis and treatment of breast cancer. Breast cancer survival rates have increased, and the number of deaths associated with this disease is steadily declining, largely due to factors such as earlier detection, a new personalized approach to treatment and a better understanding of the disease.
  • Tsen54 Pontocerebellar Hypoplasia Gene_reviews
    Other disorders to consider in the differential diagnosis Lissencephalies without known gene defects exhibiting two-layered cortex, extreme microcephaly, and cerebellar and pontine hypoplasia [Forman et al 2005] Pontocerebellar hypoplasia in extremely premature infants (<28 weeks' gestational age); an acquired phenocopy to be considered [Volpe 2009, Pierson & Al Sufiani 2016] Management Evaluations Following Initial Diagnosis To establish the extent of disease and needs in an individual diagnosed with TSEN54 pontocerebellar hypoplasia ( TSEN54 -PCH), the evaluations summarized in Table 4 (if not performed as part of the evaluation that led to the diagnosis) are recommended.
  • Cryptomnesia Wikipedia
    Shemer felt very bad when she found that it was similar to Pello Joxepe , but when Ibáñez was asked how he felt about the issue, he replied he was "glad it helped in some way", and that he was not angry, nor did he perceive it as plagiarism. [27] Tyler [ edit ] In 1984, when Aerosmith were recording Done With Mirrors , lead singer Steven Tyler heard the group's "You See Me Crying" on the radio and, not remembering that it was their own song, suggested that the group record a cover version, to which guitarist Joe Perry replied, "That's us, fuckhead!". [28] Harrison [ edit ] The precedent in United States copyright law, since 1976, has been to treat alleged cryptomnesia no differently from deliberate plagiarism.
  • Cystinuria Omim
    Font et al. (2001) reported the genomic structure of SLC7A9 and 28 new mutations in this gene that, together with 7 previously reported, characterized 79% of the mutant alleles in 61 non-type I cystinuria patients.
    SLC3A1
  • Mpv17-Related Mitochondrial Dna Maintenance Defect Gene_reviews
    Clinical Manifestations of MPV17 -Related Encephalohepatopathy View in own window Clinical Manifestations Frequency Hepatic Liver dysfunction 1 96/96 (100%) Liver failure 2 87/96 (91%) Cholestasis 70/96 (73%) Hepatomegaly 60/96 (63%) Steatosis 49/96 (51%) Liver cirrhosis 20/96 (21%) Hepatocellular cancer 3 3/96 (3%) Neurologic 4 Developmental delay 5 75/91 (82%) Hypotonia 67/91 (74%) Microcephaly 21/91 (23%) Peripheral neuropathy 6 17/91 (19%) Seizures 9/91 (10%) Dystonia 4/91 (4%) Ataxia 3/91 (3%) Abnormalities on brain MRI White matter 7 27/71 (38%) Brain stem signal 6/71 (8%) Basal ganglia signal 6/71 (8%) Gastrointestinal Failure to thrive 8 82/91 (90%) Gastrointestinal dysmotility 9 30/91 (33%) Feeding difficulties 28/91 (31%) Metabolic Lactic acidosis 10 72/91 (79%) Hypoglycemia 11 55/91 (60%) Other Renal tubulopathy 9/91 (10%) Nephrocalcinosis 7/91 (8%) Hypoparathyroidism 4/91 (4%) Retinopathy 7/91 (8%) Nystagmus 6/91 (7%) Corneal anesthesia & ulcers 4/91 (4%) 1.
  • Mecr-Related Neurologic Disorder Gene_reviews
    Heimer et al [2016] describe a male age 46 years (Family C, Patient II:2) with unintelligible speech and contractures who was confined to a wheelchair and totally dependent for all activities of daily living, whereas his brother age 28 years (Patient II:8) walked independently despite limb dystonia and had slightly slurred dysarthric – but intelligible – speech.
  • Congenital Cataracts, Facial Dysmorphism, And Neuropathy Gene_reviews
    Nervous System Hypomyelinating peripheral neuropathy is symmetric and distally accentuated, with predominantly motor involvement progressing to severe disability by the third decade of life. In a study of 28 affected children ages four months to 16 years, Kalaydjieva et al [2005] observed an invariable delay in early motor development, with all starting to walk between ages two and three years, often with an unsteady gait.
    CTDP1, SGCG
    • Congenital Cataracts-Facial Dysmorphism-Neuropathy Syndrome Orphanet
      Congenital Cataracts Facial Dysmorphism Neuropathy (CCFDN) syndrome is a complex developmental disorder of autosomal recessive inheritance. Epidemiology To date, CCFDN has been found to occur exclusively in patients of Roma (Gypsy) ethnicity; over 100 patients have been diagnosed. Clinical description Developmental abnormalities include congenital cataracts and microcorneae, primary hypomyelination of the peripheral nervous system, impaired physical growth, delayed early motor and intellectual development, mild facial dysmorphism and hypogonadism. Para-infectious rhabdomyolysis is a serious complication reported in an increasing number of patients. During general anaesthesia, patients with CCFDN require careful monitoring as they have an elevated risk of complications.
    • Congenital Cataracts, Facial Dysmorphism, And Neuropathy Medlineplus
      Congenital cataracts, facial dysmorphism, and neuropathy (CCFDN) is a rare disorder that affects several parts of the body. It is characterized by a clouding of the lens of the eyes at birth (congenital cataracts ) and other eye abnormalities, such as small or poorly developed eyes (microphthalmia) and abnormal eye movements (nystagmus). Affected individuals, particularly males, often have distinctive facial features that become more apparent as they reach adulthood. These features include a prominent midface, a large nose, protruding teeth, and a small lower jaw. CCFDN causes progressive damage to the peripheral nerves, which connect the brain and spinal cord to muscles and sensory cells.
    • Congenital Cataracts, Facial Dysmorphism, And Neuropathy Omim
      A number sign (#) is used with this entry because congenital cataracts with facial dysmorphism and neuropathy (CCFDN) is caused by homozygous mutation in the CTDP1 gene (604927) on chromosome 18q23. Description Congenital cataracts, facial dysmorphism, and neuropathy is an autosomal recessive disorder that is prevalent among Bulgarian Gypsies. Additional features include delayed psychomotor development, skeletal anomalies, and hypogonadism. The predominantly motor neuropathy becomes evident during childhood and progresses to severe disability by the third decade (Tournev et al., 1999). CCFDN is genetically distinct from Marinesco-Sjogren syndrome (MSS; 248800), although the 2 disorders share some overlapping features, including congenital cataracts, delayed psychomotor development, and ataxia (Merlini et al., 2002).
  • Complete Plasminogen Activator Inhibitor 1 Deficiency Gene_reviews
    A woman with complete PAI-1 deficiency was treated with FFP during three pregnancies at eight to 11 weeks' gestation two to three times per week; treatment was increased to daily at 20-28 weeks' gestation. The first pregnancy ended in miscarriage at 19 weeks.
  • Chd4 Neurodevelopmental Disorder Gene_reviews
    Select Features of CHD4 Neurodevelopmental Disorder View in own window Feature % of Persons with Feature Comment Speech delay 94% (29/31) Motor delay 91% (29/32) Intellectual disability 83% (19/23) Mostly mild-to-moderate ID Ophthalmologic abnormalities 74% (14/19) Congenital heart defect 72% (21/29) Hypotonia 71% (17/24) Hearing impairment 58% (11/19) Cryptorchidism 52% (11/21) Macrocephaly 46% (13/28) >90th %ile Skeletal/limb anomalies 42% (14/33) Hypogonadotropic hypogonadism 38% (8/21) Reported in males only Short stature 31% (9/29) Some w/growth hormone deficiency Hydrocephalus requiring shunting 18% (6/33) Developmental delay (DD) and intellectual disability (ID).
    CHD4
    • Sifrim-Hitz-Weiss Syndrome Omim
      A number sign (#) is used with this entry because of evidence that Sifrim-Hitz-Weiss syndrome (SIHIWES) is caused by heterozygous mutation in the CHD4 gene (603277) on chromosome 12p13. Description Sifrim-Hitz-Weiss syndrome is an autosomal dominant intellectual developmental disorder with variable congenital defects affecting other systems, including cardiac, skeletal, and urogenital. Some patients may have short stature, enlarged head circumference, hearing loss, and nonspecific dysmorphic facial features (summary by Sifrim et al., 2016 and Weiss et al., 2016). Clinical Features Sifrim et al. (2016) reported 5 unrelated patients, ranging in age from 1 to 16 years, with a syndrome associated with congenital heart defects. Three had tetralogy of Fallot (TOF) or TOF-like features, 1 had an aortic coarctation, and 1 had a septal defect.
  • Depdc5-Related Epilepsy Gene_reviews
    ., a single occurrence in a family) focal cortical dysplasia or hemimegalencephaly [D'Gama et al 2015] 4/130 individuals with infantile spasms [Carvill et al 2015] 1/17 individuals with familial mesial temporal lobe epilepsies, and 0/28 families with autosomal dominant epilepsy with auditory features [Striano et al 2015] 17/190 individuals with familial focal epilepsies, and 1/132 simplex cases with focal epilepsies [Ricos et al 2016] 2/15 unrelated probands with epilepsy with auditory features [Pippucci et al 2015] 6/61 individuals with epilepsy who died of SUDEP [Bagnall et al 2016] 4/48 unrelated probands with focal epilepsies [Weckhuysen et al 2016] 1/101 individuals with brain overgrowth [Mirzaa et al 2016] Differential Diagnosis The differential diagnosis for DEPDC5 -related epilepsy includes other focal epilepsy syndromes as well as other genetic causes of (familial) focal epilepsy and focal cortical dysplasia.
  • Schizophrenia 3 Omim
    They found an association of schizophrenia with a large set of similarly associating SNPs in the distal 2 Mb of the MHC, the most strongly associated being rs13194504 (p = 5.5 X 10(-28)). The other peak of association centered at the C4 locus, where schizophrenia associated most strongly with the genetic predictor of C4A expression levels (p = 3.6 X 10(-24)).
    CSF2, LAMC2
  • Checkpoint Kinase 2 Omim
    Among 578 men with prostate cancer (176807), Dong et al. (2003) found 28 (4.8%) germline CHEK2 mutations, 16 of which were unique.
    APC, ATM, BARD1, BRCA1, BRCA2, CYP17A1, PHB, CHEK2, WBP1L, PALB2, C11orf65
  • Cartilage-Hair Hypoplasia Omim
    Kaitila and Perheentupa (1980) referred to 33 cases of cartilage-hair hypoplasia in 28 families in Finland. In Finland, Makitie et al. (1999) reviewed 122 patients with CHH who had been identified in 2 countrywide epidemiologic surveys in 1974 and in 1986.
    RMRP, MARCKSL1, ABCC1, WLS, ANOS1, FGFR1, CHD7, EBP, GNRHR, AMH, PROK2, CGB5, SPRY2, KLB, POP1, CORO1A, CGB8, FLRT3, FGF21, SPRY4, POP5, IL17RD, RSAD2, RPP25, NTN1, WDR11, POP7, TACR3, HS6ST1, HTC2, CGA, CGB3, CYP3A4, DUSP6, FGF8, FN1, GH1, GNRH1, IL11, FGF17, CXCL10, LHCGR, SMAD2, NR3C2, NME1, SOX4, TAC3, CAT, IGSF10
    • Cartilage-Hair Hypoplasia Medlineplus
      Cartilage-hair hypoplasia is a disorder of bone growth characterized by short stature (dwarfism) with other skeletal abnormalities; fine, sparse hair (hypotrichosis ); and abnormal immune system function (immune deficiency) that can lead to recurrent infections. People with cartilage-hair hypoplasia have unusually short limbs and short stature from birth. They typically have malformations in the cartilage near the ends of the long bones in the arms and legs (metaphyseal chondrodysplasia), which then affects development of the bone itself. Most people with cartilage-hair hypoplasia are unusually flexible in some joints, but they may have difficulty extending their elbows fully. Affected individuals have hair that is lighter in color than that of other family members because the core of each hair, which contains some of the pigment that contributes the hair's color, is missing.
    • Cartilage–hair Hypoplasia Wikipedia
      This article needs additional citations for verification . Please help improve this article by adding citations to reliable sources . Unsourced material may be challenged and removed. Find sources: "Cartilage–hair hypoplasia" – news · newspapers · books · scholar · JSTOR ( May 2018 ) ( Learn how and when to remove this template message ) Cartilage-hair hypoplasia Other names = McKusick type metaphyseal chondrodysplasia , [1] : 578 Cartilage-hair hypoplasia has an autosomal recessive pattern of inheritance Pronunciation / ˌ k ɑːr t ɪ l ɪ dʒ ... ˌ h aɪ p oʊ ˈ p l eɪ ʒ ə / Symptoms Short limb dwarfism Very fine thin light hairs and eyebrows Hyperextensible joints of hand and feet Abnormalities of spine Neutropenia Defective antibody and cell mediated immunity Cartilage–hair hypoplasia ( CHH ) is a rare genetic disorder . Symptoms may include short-limbed dwarfism due to skeletal dysplasia , variable level of immunodeficiency , and predisposition to cancer . It was first reported in 1965 by McKusick. Contents 1 Signs and symptoms 2 Genetics 2.1 Immunodeficiency 3 Diagnosis 4 Treatment 5 See also 6 References 7 Further reading 8 External links Signs and symptoms [ edit ] Short limb dwarfism very fine thin light hairs and eyebrows hyperextensible joints of hand and feet abnormalities of spine neutropenia defective antibody and cell mediated immunity Genetics [ edit ] Phytohemagglutinin CHH is an autosomal recessive [2] inherited disorder.
    • Cartilage-Hair Hypoplasia Gard
      Cartilage-hair hypoplasia is a disorder of bone growth characterized by short stature ( dwarfism ) with other skeletal abnormalities; fine, sparse hair (hypotrichosis); and abnormal immune system function (immune deficiency) that can lead to recurrent infections. Signs and symptoms may vary among affected individuals. People with this condition are also at an increased risk of developing cancer, particularly blood, skin, and immune system cancers. Gastrointestinal problems are also common. Cartilage-hair hypoplasia is caused by mutations in the RMRP gene and is inherited in an autosomal recessive fashion.
    • Cartilage-Hair Hypoplasia Orphanet
      Cartilage-hair hypoplasia is a disease affecting the bone metaphyses causing small stature from birth. Epidemiology Prevalence is unknown. Clinical description The disease is associated with fine, slow growing hair, and sometimes with immune deficiencies. Other symptoms include short hands and possibly short, deformed limbs (varus). X-ray reveals metaphyseal lesions, especially in the knees, and large, round epiphyses during childhood. Short stature is common and has very early onset but immune deficiency is not always present.
  • Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 1 Omim
    Despite nasogastric feeding, malnutrition was a problem, requiring continuous gastrostomy feeding from 19 to 28 months of age. A verbal IQ of 104 and a performance IQ of 90 was observed at 4 years of age.
    HELLS, CDCA7, DNMT3B
    • Icf Syndrome Orphanet
      The Immunodeficiency, Centromeric region instability, Facial anomalies syndrome (ICF) is a rare autosomal recessive disease characterized by immunodeficiency, although B cells are present, and by characteristic rearrangements in the vicinity of the centromeres (the juxtacentromeric heterochromatin) of chromosomes 1 and 16 and sometimes 9. Epidemiology ICF has been described in about 50 patients worldwide. Clinical description Other variable symptoms of this probably under-diagnosed syndrome include mild facial dysmorphism, growth retardation, failure to thrive, and psychomotor retardation. Serum levels of IgG, IgM, IgE, and/or IgA are low, although the type of immunoglobulin deficiency is variable. Recurrent infections are the presenting symptom, usually in early childhood. Etiology ICF always involves limited hypomethylation of DNA and often arises from mutations in one of the DNA methyltransferase genes ( DNMT3B ).
    • Immunodeficiency–centromeric Instability–facial Anomalies Syndrome Wikipedia
      This article needs additional citations for verification . Please help improve this article by adding citations to reliable sources . Unsourced material may be challenged and removed. Find sources: "Immunodeficiency–centromeric instability–facial anomalies syndrome" – news · newspapers · books · scholar · JSTOR ( August 2008 ) ( Learn how and when to remove this template message ) ICF syndrome Other names Immunodeficiency-centromeric instability-facial anomalies syndrome ICF syndrome (or I mmunodeficiency, C entromere instability and F acial anomalies syndrome ) [1] is a very rare autosomal recessive [2] immune disorder . Contents 1 Presentation 2 Genetics 3 Diagnosis 4 Treatment 5 See also 6 References 7 External links Presentation [ edit ] It is characterized by variable reductions in serum immunoglobulin levels which cause most ICF patients to succumb to infectious diseases before adulthood . ICF syndrome patients exhibit facial anomalies which include hypertelorism , low-set ears , epicanthal folds and macroglossia . Genetics [ edit ] Mutations in four genes can cause this syndrome: [3] Cell division cycle associated protein 7 ( CDCA7 ), DNA-methyltransferase 3b ( DNMT3B ), Lymphoid specific helicase ( HELLS ) and Zinc finger- and BTB domain containing protein 24 ( ZBTB24 ).
  • ←
  • 1
  • 2
    • ...
  • 152
  • 153
  • 154
  • 155
  • 156
  • 157
  • 158
    • ...
  • 188
  • 189
  • →

FindZebra

contact@findzebra.com