-
Hashimoto's Thyroiditis
Wikipedia
., i.e. transmits an inhibitory signal to T cells, so reduced functioning is associated with increased T-lymphocyte activity. [18] [19] A family history of thyroid disorders is common, with the HLA-DR5 gene most strongly implicated conferring a relative risk of 3 in the UK. [20] Having other autoimmune diseases is a risk factor to develop Hashimoto’s thyroiditis, and the opposite is also true. [1] Autoimmune diseases most commonly associated to Hashimoto’s thyroiditis include celiac disease , type 1 diabetes , vitiligo , and alopecia . [21] Preventable environmental factors, including high iodine intake, selenium deficiency , and infectious diseases and certain drugs, have been implicated in the development of autoimmune thyroid disease in genetically predisposed individuals. [22] The genes implicated vary in different ethnic groups and the incidence is increased in people with chromosomal disorders, including Turner , Down , and Klinefelter syndromes usually associated with autoantibodies against thyroglobulin and thyroperoxidase . ... Severe thyroid atrophy presents often with denser fibrotic bands of collagen that remains within the confines of the thyroid capsule. [24] Diagnosis [ edit ] Ultrasound imaging of the thyroid gland (right lobe longitudinal) in a person with Hashimoto thyroiditis Diagnosis is usually made by detecting elevated levels of antithyroid peroxidase antibodies in the serum, but seronegative (without circulating autoantibodies) thyroiditis is also possible. [25] Given the relatively nonspecific symptoms of initial hypothyroidism, Hashimoto's thyroiditis is often misdiagnosed as depression , cyclothymia , premenstrual syndrome , chronic fatigue syndrome , fibromyalgia , and less frequently, as erectile dysfunction or an anxiety disorder . ... Lymphocytic infiltration of the thyrocyte -associated tissues often leads to the histologically significant finding of germinal center development within the thyroid gland. [ citation needed ] Hashimoto's when presenting as mania is known as Prasad's syndrome after Ashok Prasad, the psychiatrist who first described it. [28] Treatment [ edit ] Managing hormone levels [ edit ] Hypothyroidism caused by Hashimoto's thyroiditis is treated with thyroid hormone replacement agents such as levothyroxine , triiodothyronine , or desiccated thyroid extract . ... Retrieved 4 December 2017 . ^ "Prasad's syndrome" . Archived from the original on 9 June 2011. ^ "Does Your Doctor Know About the New TSH Lab Standards?" ... Classification D ICD - 10 : E06.3 ICD - 9-CM : 245.2 OMIM : 140300 MeSH : D050031 DiseasesDB : 5649 External resources eMedicine : med/949 Patient UK : Hashimoto's thyroiditis v t e Thyroid disease Hypothyroidism Iodine deficiency Cretinism Congenital hypothyroidism Myxedema Myxedema coma Euthyroid sick syndrome Signs and symptoms Queen Anne's sign Woltman sign Thyroid dyshormonogenesis Pickardt syndrome Hyperthyroidism Hyperthyroxinemia Thyroid hormone resistance Familial dysalbuminemic hyperthyroxinemia Hashitoxicosis Thyrotoxicosis factitia Thyroid storm Graves' disease Signs and symptoms Abadie's sign of exophthalmic goiter Boston's sign Dalrymple's sign Stellwag's sign lid lag Griffith's sign Möbius sign Pretibial myxedema Graves' ophthalmopathy Thyroiditis Acute infectious Subacute De Quervain's Subacute lymphocytic Palpation Autoimmune /chronic Hashimoto's Postpartum Riedel's Enlargement Goitre Endemic goitre Toxic nodular goitre Toxic multinodular goiter Thyroid nodule Colloid nodule v t e Hypersensitivity and autoimmune diseases Type I / allergy / atopy ( IgE ) Foreign Atopic eczema Allergic urticaria Allergic rhinitis (Hay fever) Allergic asthma Anaphylaxis Food allergy common allergies include: Milk Egg Peanut Tree nut Seafood Soy Wheat Penicillin allergy Autoimmune Eosinophilic esophagitis Type II / ADCC IgM IgG Foreign Hemolytic disease of the newborn Autoimmune Cytotoxic Autoimmune hemolytic anemia Immune thrombocytopenic purpura Bullous pemphigoid Pemphigus vulgaris Rheumatic fever Goodpasture syndrome Guillain–Barré syndrome " Type V "/ receptor Graves' disease Myasthenia gravis Pernicious anemia Type III ( Immune complex ) Foreign Henoch–Schönlein purpura Hypersensitivity vasculitis Reactive arthritis Farmer's lung Post-streptococcal glomerulonephritis Serum sickness Arthus reaction Autoimmune Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis Type IV / cell-mediated ( T cells ) Foreign Allergic contact dermatitis Mantoux test Autoimmune Diabetes mellitus type 1 Hashimoto's thyroiditis Multiple sclerosis Coeliac disease Giant-cell arteritis Postorgasmic illness syndrome Reactive arthritis GVHD Transfusion-associated graft versus host disease Unknown/ multiple Foreign Hypersensitivity pneumonitis Allergic bronchopulmonary aspergillosis Transplant rejection Latex allergy (I+IV) Autoimmune Sjögren syndrome Autoimmune hepatitis Autoimmune polyendocrine syndrome APS1 APS2 Autoimmune adrenalitis Systemic autoimmune disease Authority control GND : 4357666-7 NSK : 000216146TG, CTLA4, C1S, IL2RA, PTPN22, FOXD3, VAV3, PTEN, TRIM60, DCLRE1C, BACH2, HT, TTC7A, CA10, HLA-DRB1, TPO, POLG, PLCG2, CLCNKB, TBX2, IFNG, TSHR, RET, TIMM23, BRAF, SLC12A3, IL6, SEC23B, IL17A, SLC25A27, LPP, MIR3681HG, TNF, CXCL10, VDR, FOXP3, SLC6A4, IL10, IL1B, FAS, ISG20, TGFB1, RBM45, CD274, ATN1, HLA-DQA1, ICAM1, PTCH1, TP53, IL37, FASLG, LINC01193, KRT19, HLA-C, IL4, IL23R, CCDC6, SELENOS, SLC5A5, IL23A, CD40, F9, BCL2, IL18, MIR125A, TAS2R38, HLA-DQB1, STAT3, LGALS3, TSHB, IFNA13, MIR155, CAV1, IFNA1, MIR146A, CALCA, CASP8, HLA-G, IL5, TLR2, NCAM1, SIRT1, MBL2, SPP1, AQP3, IL1RL1, SLC26A4, PIK3CA, CD24, ICOS, INS, HLA-DRB4, IL12B, MIR451A, CLDN1, IL15, TRBV20OR9-2, S100A9, IFIH1, DPP4, CD68, EDN1, IL33, PTPRC, EPHB2, PTGS2, ESR1, ESR2, HLA-DPB1, CYP27B1, FCGRT, FLNB, FCRL3, IL17F, S100A8, AITD1, H2AC14, PPARG, HLA-B, HLA-A, HIF1A, MAPK1, TNFSF4, WDR11, TERT, AIM2, PDLIM7, MAGI2, GNA14, VIP, VEGFA, CD83, UBE2B, TK1, NCOA4, THRB, CDR3, EOMES, RASGRP1, TNFSF18, TLR4, IL18R1, IL18RAP, TNFRSF25, TNFSF10, UBE2L3, ABCA1, TNFSF13B, SCGB3A2, TPH2, EARS2, DOCK11, CEP128, IL34, SLC5A8, TIGIT, IFNL3, IFNL1, MIRLET7E, MIR142, MIR210, MIR22, MIR223, MIR27A, MIR29A, XRCC6P5, MIR326, SNORA21, KIR2DS2, LINC01672, PSC, IFNG-AS1, CERNA3, MTCO2P12, IP6K3, FCRL1, BTG3, ABCC11, PTGDR2, ECD, IKZF3, IKZF2, IL17RA, AGO2, IGHV3-23, SETD2, TBX21, IL21R, IL22, F11R, GHRL, SDK2, BANK1, CHDH, ZFAT, HAMP, C6orf47, IL21, FCRL2, UNC93B1, TLR10, FBN3, FCRLA, MBIP, PSMB9, TBX1, CCR5, CLDN7, CSF1R, CTSB, CTSS, CYBB, CYP19A1, DAP, DCK, DIO2, DNASE1, EDNRA, EPAS1, ERBB2, ETS1, F3, FCGR2B, FOXO3, MTOR, GAST, GAD1, GAD2, GAS6, GATA3, GEM, GHRH, GJA1, GLUL, GPX3, GZMB, COL1A1, CDX2, ABCC8, CD81, ADA, AFP, AGER, JAG1, AMH, AIRE, APOA1, AQP4, AVP, CCND1, BCL6, BDNF, BGLAP, BLK, C3, CASP3, CD1A, CD1C, CD3G, CD14, CD19, CD27, CD28, CD80, CD86, TNFRSF8, TNFSF8, SCARB1, CD38, HLA-DOA, HMGB1, IRF8, IFNA2, PIK3CB, PIK3CD, PIK3CG, PLAT, PRKAR1A, PRKCE, ACP1, PTGDS, PTH, RAB4A, MOK, RARA, RARG, RASGRF1, RENBP, S100A1, S100B, ATXN2, CCL5, CXCL11, SELENOP, SLAMF1, SLC22A4, SMN1, SMN2, SOAT1, SOS1, STAT1, STAT4, PCYT1A, PCNA, NT5E, SH2D1A, IGF1, IGH, IL1A, IL1RN, IL6R, IL7, IRAK2, ITGAL, ITGB2, KIR2DL2, KIR3DL1, KIT, LTA, MAOB, NRAS, MIF, CXCL9, NR3C2, MMP3, MMP9, COX2, NUDT1, MTTP, MTRR, MYC, NDUFB2, NFKB1, NFKBIA, LINC02605
-
Hypokalemia
Wikipedia
These include renal artery stenosis and tumors (generally nonmalignant) of the adrenal glands, e.g., Conn's syndrome (primary hyperaldosteronism ). Cushing's syndrome can also lead to hypokalemia due to excess cortisol binding the Na + /K + pump and acting like aldosterone. ... This deficiency—known as apparent mineralocorticoid excess syndrome —can either be congenital or caused by consumption of glycyrrhizin , which is contained in extract of licorice , sometimes found in herbal supplements , candies , and chewing tobacco. Rare hereditary defects of renal salt transporters, such as Bartter syndrome or Gitelman syndrome , can cause hypokalemia, in a manner similar to that of diuretics. ... Concomitant hypomagnesemia will inhibit potassium replacement, as magnesium is a cofactor for potassium uptake. [23] Popular culture [ edit ] The plot of the science fiction novel Destiny's Road by Larry Niven centers around the setting's scarcity of available potassium, and the resulting deficiency and its effects on the world's colonists and their society. [27] [28] [29] [30] See also [ edit ] Bartter syndrome Gitelman syndrome Hypokalemic acidosis Potassium deficiency (plant disorder) Superior mesenteric artery syndrome References [ edit ] ^ a b c d e f g h i j k l m n o p Soar, J; Perkins, GD; Abbas, G; Alfonzo, A; Barelli, A; Bierens, JJ; Brugger, H; Deakin, CD; Dunning, J; Georgiou, M; Handley, AJ; Lockey, DJ; Paal, P; Sandroni, C; Thies, KC; Zideman, DA; Nolan, JP (October 2010).NR3C1, ADRB2, SST, POMC, INS, NPPB, AGT, NOS1AP, USP8, OCRL, CDH23, SCN4A, SCN4B, SCN5A, SCN10A, MAGED2, SCNN1A, SCNN1B, TRDN, SCNN1G, SLC2A2, SLC4A1, SLC12A1, AKAP9, SNTA1, KCNE2, TP53, BSND, AIP, CLDN10, SLC12A3, KCNQ1, SMAD4, KCNJ10, ANK2, ATP1A1, FXYD2, BMPR1A, CACNA1D, CACNA1S, CALM1, CALM2, CAV3, CLCN2, CLCNKA, CLCNKB, COL3A1, CTNS, CYP11B1, CYP11B2, CYP17A1, SLC26A3, HMBS, HSD11B2, KCNE1, KCNH2, KCNJ1, KCNJ2, KCNJ5, KCNJ18, SLC26A7
-
Postterm Pregnancy
Wikipedia
Postterm pregnancy Other names Post-term, postmaturity, prolonged pregnancy, post-dates pregnancy, postmature birth Specialty Obstetrics Postterm pregnancy is when a woman has not yet delivered her baby after 42 weeks of gestation , two weeks beyond the typical 40 week duration of pregnancy. [1] Post-mature births carry risks for both the mother and the baby, including fetal malnutrition, meconium aspiration syndrome , and stillbirths . [2] After the 42nd week of gestation, the placenta , which supplies the baby with nutrients and oxygen from the mother, starts aging and will eventually fail. ... It is common to encounter the following terms when describing different time periods of pregnancy. [4] Postterm - ≥ 42 weeks + 0 days of gestation (≥ 294 days from the first day of last menstrual period, or ≥ 14 days from the estimated due date) Late term - 41 weeks + 0 days to 41 weeks + 6 days of gestation Full term - 39 weeks + 0 days to 40 weeks + 6 days of gestation Early term - 37 weeks + 0 days to 38 weeks + 6 days of gestation Preterm - ≤ 36 weeks + 6 days of gestation [5] Besides postterm pregnancy, other terminologies have been used to describe the same condition (≥ 42w+0d), such as prolonged pregnancy, postdates, and postdatism. [6] However, these terminologies are less commonly used to avoid confusion. [7] Postterm pregnancy should not be confused with postmaturity, postmaturity syndrome, or dysmaturity. These terms describe the neonatal condition that may be caused by postterm pregnancy instead of the duration of pregnancy. [6] Signs and symptoms [ edit ] Because postterm pregnancy is a condition solely based on gestational age, there are no confirming physical signs or symptoms. ... It is associated with complications such as cord compression, abnormal heart rate, fetal acidosis, and meconium amniotic fluid. [10] Meconium aspiration syndrome —Respiratory compromise secondary to meconium present in infant's lungs. [11] Macrosomia —Estimated fetal weight of ≥ 4.5 kg. ... CS1 maint: multiple names: authors list ( link ) External links [ edit ] Classification D ICD - 10 : O48 , P08.2 ICD - 9-CM : 766.22 MeSH : D007233 DiseasesDB : 10417 External resources eMedicine : med/3248 v t e Pathology of pregnancy , childbirth and the puerperium Pregnancy Pregnancy with abortive outcome Abortion Ectopic pregnancy Abdominal Cervical Interstitial Ovarian Heterotopic Embryo loss Fetal resorption Molar pregnancy Miscarriage Stillbirth Oedema , proteinuria and hypertensive disorders Gestational hypertension Pre-eclampsia HELLP syndrome Eclampsia Other, predominantly related to pregnancy Digestive system Acute fatty liver of pregnancy Gestational diabetes Hepatitis E Hyperemesis gravidarum Intrahepatic cholestasis of pregnancy Integumentary system / dermatoses of pregnancy Gestational pemphigoid Impetigo herpetiformis Intrahepatic cholestasis of pregnancy Linea nigra Prurigo gestationis Pruritic folliculitis of pregnancy Pruritic urticarial papules and plaques of pregnancy (PUPPP) Striae gravidarum Nervous system Chorea gravidarum Blood Gestational thrombocytopenia Pregnancy-induced hypercoagulability Maternal care related to the fetus and amniotic cavity amniotic fluid Oligohydramnios Polyhydramnios Braxton Hicks contractions chorion / amnion Amniotic band syndrome Chorioamnionitis Chorionic hematoma Monoamniotic twins Premature rupture of membranes Obstetrical bleeding Antepartum placenta Circumvallate placenta Monochorionic twins Placenta accreta Placenta praevia Placental abruption Twin-to-twin transfusion syndrome Labor Amniotic fluid embolism Cephalopelvic disproportion Dystocia Shoulder dystocia Fetal distress Locked twins Nuchal cord Obstetrical bleeding Postpartum Pain management during childbirth placenta Placenta accreta Preterm birth Postmature birth Umbilical cord prolapse Uterine inversion Uterine rupture Vasa praevia Puerperal Breastfeeding difficulties Low milk supply Cracked nipples Breast engorgement Childbirth-related posttraumatic stress disorder Diastasis symphysis pubis Postpartum bleeding Peripartum cardiomyopathy Postpartum depression Postpartum psychosis Postpartum thyroiditis Puerperal fever Puerperal mastitis Other Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy Category v t e Conditions originating in the perinatal period / fetal disease Maternal factors complicating pregnancy, labour or delivery placenta Placenta praevia Placental insufficiency Twin-to-twin transfusion syndrome chorion / amnion Chorioamnionitis umbilical cord Umbilical cord prolapse Nuchal cord Single umbilical artery presentation Breech birth Asynclitism Shoulder presentation Growth Small for gestational age / Large for gestational age Preterm birth / Postterm pregnancy Intrauterine growth restriction Birth trauma scalp Cephalohematoma Chignon Caput succedaneum Subgaleal hemorrhage Brachial plexus injury Erb's palsy Klumpke paralysis Affected systems Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome Pleural disease Pneumothorax Pneumomediastinum Wilson–Mikity syndrome Bronchopulmonary dysplasia Cardiovascular Pneumopericardium Persistent fetal circulation Bleeding and hematologic disease Vitamin K deficiency bleeding HDN ABO Anti-Kell Rh c Rh D Rh E Hydrops fetalis Hyperbilirubinemia Kernicterus Neonatal jaundice Velamentous cord insertion Intraventricular hemorrhage Germinal matrix hemorrhage Anemia of prematurity Gastrointestinal Ileus Necrotizing enterocolitis Meconium peritonitis Integument and thermoregulation Erythema toxicum Sclerema neonatorum Nervous system Perinatal asphyxia Periventricular leukomalacia Musculoskeletal Gray baby syndrome muscle tone Congenital hypertonia Congenital hypotonia Infections Vertically transmitted infection Neonatal infection rubella herpes simplex mycoplasma hominis ureaplasma urealyticum Omphalitis Neonatal sepsis Group B streptococcal infection Neonatal conjunctivitis Other Miscarriage Perinatal mortality Stillbirth Infant mortality Neonatal withdrawal
-
New Daily Persistent Headache
Wikipedia
New daily persistent headache Specialty Neurology New daily persistent headache ( NDPH ) is a primary headache syndrome which can mimic chronic migraine and chronic tension-type headache . ... Infection or flu-like illness and stressful life event are most often cited. [1] The pathophysiology of NDPH is poorly understood. The syndrome is difficult to treat and may persist for years. ... It is one of the types of primary headache syndromes that present as a chronic daily headache, which is a headache present for more than 15 days a month for more than 3 months. ... "New daily persistent headaches: definition of a benign syndrome". Headache . 26 : 317. doi : 10.1111/j.1526-4610.1986.t01-1-.x . ^ Silberstein, Stephen D.; Lipton, Richard B.; Solomon, Seymour; Mathew, Ninan T. (1994). ... "New Daily Persistent Headache: A Syndrome Not a Discrete Disorder". Headache: The Journal of Head and Face Pain . 51 (4): 650–3. doi : 10.1111/j.1526-4610.2011.01872.x .
-
Emotional And Behavioral Disorders
Wikipedia
Behaviour Management (EBD) Review Group: Published reviews Classification D ICD - 10 : F90 – F98 ICD - 9-CM : 312 v t e Mental and behavioral disorders Adult personality and behavior Gender dysphoria Ego-dystonic sexual orientation Paraphilia Fetishism Voyeurism Sexual maturation disorder Sexual relationship disorder Other Factitious disorder Munchausen syndrome Intermittent explosive disorder Dermatillomania Kleptomania Pyromania Trichotillomania Personality disorder Childhood and learning Emotional and behavioral ADHD Conduct disorder ODD Emotional and behavioral disorders Separation anxiety disorder Movement disorders Stereotypic Social functioning DAD RAD Selective mutism Speech Stuttering Cluttering Tic disorder Tourette syndrome Intellectual disability X-linked intellectual disability Lujan–Fryns syndrome Psychological development ( developmental disabilities ) Pervasive Specific Mood (affective) Bipolar Bipolar I Bipolar II Bipolar NOS Cyclothymia Depression Atypical depression Dysthymia Major depressive disorder Melancholic depression Seasonal affective disorder Mania Neurological and symptomatic Autism spectrum Autism Asperger syndrome High-functioning autism PDD-NOS Savant syndrome Dementia AIDS dementia complex Alzheimer's disease Creutzfeldt–Jakob disease Frontotemporal dementia Huntington's disease Mild cognitive impairment Parkinson's disease Pick's disease Sundowning Vascular dementia Wandering Other Delirium Organic brain syndrome Post-concussion syndrome Neurotic , stress -related and somatoform Adjustment Adjustment disorder with depressed mood Anxiety Phobia Agoraphobia Social anxiety Social phobia Anthropophobia Specific social phobia Specific phobia Claustrophobia Other Generalized anxiety disorder OCD Panic attack Panic disorder Stress Acute stress reaction PTSD Dissociative Depersonalization disorder Dissociative identity disorder Fugue state Psychogenic amnesia Somatic symptom Body dysmorphic disorder Conversion disorder Ganser syndrome Globus pharyngis Psychogenic non-epileptic seizures False pregnancy Hypochondriasis Mass psychogenic illness Nosophobia Psychogenic pain Somatization disorder Physiological and physical behavior Eating Anorexia nervosa Bulimia nervosa Rumination syndrome Other specified feeding or eating disorder Nonorganic sleep Hypersomnia Insomnia Parasomnia Night terror Nightmare REM sleep behavior disorder Postnatal Postpartum depression Postpartum psychosis Sexual dysfunction Arousal Erectile dysfunction Female sexual arousal disorder Desire Hypersexuality Hypoactive sexual desire disorder Orgasm Anorgasmia Delayed ejaculation Premature ejaculation Sexual anhedonia Pain Nonorganic dyspareunia Nonorganic vaginismus Psychoactive substances, substance abuse and substance-related Drug overdose Intoxication Physical dependence Rebound effect Stimulant psychosis Substance dependence Withdrawal Schizophrenia , schizotypal and delusional Delusional Delusional disorder Folie à deux Psychosis and schizophrenia-like Brief reactive psychosis Schizoaffective disorder Schizophreniform disorder Schizophrenia Childhood schizophrenia Disorganized (hebephrenic) schizophrenia Paranoid schizophrenia Pseudoneurotic schizophrenia Simple-type schizophrenia Other Catatonia Symptoms and uncategorized Impulse control disorder Klüver–Bucy syndrome Psychomotor agitation Stereotypy v t e Emotional and behavioral disorders Emotional/behavioral ADHD Conduct disorder Oppositional defiant disorder Emotional/behavioral disorder (EBD) Separation anxiety Social functioning Selective mutism RAD DAD Tic disorders Tourette syndrome Speech disorders Stuttering Cluttering Stereotypic movement disorder Elimination disorders Enuresis Encopresis
-
Neonatal Jaundice
Wikipedia
This causes an accumulation of bilirubin in the blood ( hyperbilirubinemia ), leading to the symptoms of jaundice. [ citation needed ] If the neonatal jaundice is not resolved with simple phototherapy , other causes such as biliary atresia , Progressive familial intrahepatic cholestasis , bile duct paucity, Alagille syndrome , alpha 1-antitrypsin deficiency , and other pediatric liver diseases should be considered. ... HbH disease Extrinsic causes of hemolysis [ edit ] Systemic conditions Sepsis Arteriovenous malformation Alloimmunity (The neonatal or cord blood gives a positive direct Coombs test and the maternal blood gives a positive indirect Coombs test ) Hemolytic disease of the newborn (ABO) [11] Rh disease [11] Hemolytic disease of the newborn (anti-Kell) Hemolytic disease of the newborn (anti-Rhc) Other blood type mismatches causing hemolytic disease of the newborn Non-hemolytic causes [ edit ] Breastfeeding jaundice Breast milk jaundice Cephalohematoma Polycythemia Urinary tract infection Sepsis Hypothyroidism Gilbert's syndrome Crigler–Najjar syndrome High GI obstruction ( Pyloric stenosis , Bowel obstruction ) Conjugated (Direct) [ edit ] Liver causes [ edit ] Infections Sepsis Hepatitis A Hepatitis B TORCH infections Metabolic Galactosemia Alpha 1-antitrypsin deficiency , which is commonly missed, and must be considered in DDx Cystic fibrosis Dubin–Johnson syndrome Rotor syndrome Drugs Total parenteral nutrition Idiopathic Post-liver [ edit ] Biliary atresia or bile duct obstruction Alagille syndrome Choledochal cyst Non-organic causes [ edit ] Breastfeeding jaundice [ edit ] "Breastfeeding jaundice" (or "lack of breastfeeding jaundice") is caused by insufficient breast milk intake, [12] resulting in inadequate quantities of bowel movements to remove bilirubin from the body. ... Classification D ICD - 10 : P58 , P59 ICD - 9-CM : 773 , 774 MeSH : D007567 DiseasesDB : 8881 External resources MedlinePlus : 001559 eMedicine : ped/1061 Patient UK : Neonatal jaundice v t e Conditions originating in the perinatal period / fetal disease Maternal factors complicating pregnancy, labour or delivery placenta Placenta praevia Placental insufficiency Twin-to-twin transfusion syndrome chorion / amnion Chorioamnionitis umbilical cord Umbilical cord prolapse Nuchal cord Single umbilical artery presentation Breech birth Asynclitism Shoulder presentation Growth Small for gestational age / Large for gestational age Preterm birth / Postterm pregnancy Intrauterine growth restriction Birth trauma scalp Cephalohematoma Chignon Caput succedaneum Subgaleal hemorrhage Brachial plexus injury Erb's palsy Klumpke paralysis Affected systems Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome Pleural disease Pneumothorax Pneumomediastinum Wilson–Mikity syndrome Bronchopulmonary dysplasia Cardiovascular Pneumopericardium Persistent fetal circulation Bleeding and hematologic disease Vitamin K deficiency bleeding HDN ABO Anti-Kell Rh c Rh D Rh E Hydrops fetalis Hyperbilirubinemia Kernicterus Neonatal jaundice Velamentous cord insertion Intraventricular hemorrhage Germinal matrix hemorrhage Anemia of prematurity Gastrointestinal Ileus Necrotizing enterocolitis Meconium peritonitis Integument and thermoregulation Erythema toxicum Sclerema neonatorum Nervous system Perinatal asphyxia Periventricular leukomalacia Musculoskeletal Gray baby syndrome muscle tone Congenital hypertonia Congenital hypotonia Infections Vertically transmitted infection Neonatal infection rubella herpes simplex mycoplasma hominis ureaplasma urealyticum Omphalitis Neonatal sepsis Group B streptococcal infection Neonatal conjunctivitis Other Miscarriage Perinatal mortality Stillbirth Infant mortality Neonatal withdrawal
-
Cardiomegaly
Wikipedia
Please help improve this article if you can. ( May 2020 ) ( Learn how and when to remove this template message ) Cardiomegaly Cardiomegaly on chest X-ray with a pacemaker Specialty Cardiology Types Athletic heart syndrome , [1] Ventricular hypertrophy , Atrial enlargement Causes Dilated cardiomyopathy , [2] [3] [4] [5] Hypertrophic cardiomyopathy . [1] [6] [7] [8] [9] Diagnostic method Hypertrophic cardiomyopathy screening [10] [11] Cardiomegaly (sometimes megacardia or megalocardia ) is a medical condition in which the heart is enlarged. ... For example, the athletic heart syndrome is a non- pathological condition commonly seen in sports medicine in which the human heart is enlarged, and the resting heart rate is lower than normal. ... External links [ edit ] Classification D ICD - 10 : I51.7 ICD - 9-CM : 429.3 MeSH : D006332 DiseasesDB : 30769 American Heart Association v t e Cardiovascular disease (heart) Ischaemic Coronary disease Coronary artery disease (CAD) Coronary artery aneurysm Spontaneous coronary artery dissection (SCAD) Coronary thrombosis Coronary vasospasm Myocardial bridge Active ischemia Angina pectoris Prinzmetal's angina Stable angina Acute coronary syndrome Myocardial infarction Unstable angina Sequelae hours Hibernating myocardium Myocardial stunning days Myocardial rupture weeks Aneurysm of heart / Ventricular aneurysm Dressler syndrome Layers Pericardium Pericarditis Acute Chronic / Constrictive Pericardial effusion Cardiac tamponade Hemopericardium Myocardium Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Tachycardia-induced Restrictive Loeffler endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular dysplasia Endocardium / valves Endocarditis infective endocarditis Subacute bacterial endocarditis non-infective endocarditis Libman–Sacks endocarditis Nonbacterial thrombotic endocarditis Valves mitral regurgitation prolapse stenosis aortic stenosis insufficiency tricuspid stenosis insufficiency pulmonary stenosis insufficiency Conduction / arrhythmia Bradycardia Sinus bradycardia Sick sinus syndrome Heart block : Sinoatrial AV 1° 2° 3° Intraventricular Bundle branch block Right Left Left anterior fascicle Left posterior fascicle Bifascicular Trifascicular Adams–Stokes syndrome Tachycardia ( paroxysmal and sinus ) Supraventricular Atrial Multifocal Junctional AV nodal reentrant Junctional ectopic Ventricular Accelerated idioventricular rhythm Catecholaminergic polymorphic Torsades de pointes Premature contraction Atrial Junctional Ventricular Pre-excitation syndrome Lown–Ganong–Levine Wolff–Parkinson–White Flutter / fibrillation Atrial flutter Ventricular flutter Atrial fibrillation Familial Ventricular fibrillation Pacemaker Ectopic pacemaker / Ectopic beat Multifocal atrial tachycardia Pacemaker syndrome Parasystole Wandering atrial pacemaker Long QT syndrome Andersen–Tawil Jervell and Lange-Nielsen Romano–Ward Cardiac arrest Sudden cardiac death Asystole Pulseless electrical activity Sinoatrial arrest Other / ungrouped hexaxial reference system Right axis deviation Left axis deviation QT Short QT syndrome T T wave alternans ST Osborn wave ST elevation ST depression Strain pattern Cardiomegaly Ventricular hypertrophy Left Right / Cor pulmonale Atrial enlargement Left Right Athletic heart syndrome Other Cardiac fibrosis Heart failure Diastolic heart failure Cardiac asthma Rheumatic fever Medicine portalEDN1, NOS3, ATP2A2, NPPA, PPARD, SIRT6, CAV1, AGT, GSK3B, IL1B, PRKCA, PRKCB, HAND2, FGF2, CYP1B1, MFN2, NPPB, MYBPC3, RRAD, TNNT2, PPARA, IL18, HTR2B, GATA4, SOX4, SRC, MT2A, AKAP5, SLC2A4, ROCK2, ITPR2, FHL2, STAT3, PIK3CG, GAS6, HIF1A, HMOX1, PLPP3, SHC1, IGF1, GSN, REN, IDH2, UCP2, TNF, HRC, DMD, TRPC1, HDAC2, PRKCZ, CAV3, CCND2, AOC1, POMC, PLD2, TBX20, PLD1, TRIM63, AKT1, AHR, MYOCD, GRK2, ADRA2C, ADRA2A, ADRA1B, FNDC5, MIR125B2, MIR21, NPR1, PRKAA2, SOD2, NKX2-5, BAMBI, CABIN1, SIRT4, CPT1B, LIF, GLRX3, RBCK1, CYP2E1, CYP1A1, CTF1, AGTR1, ACE, RCAN1, MAPK1, CORIN, S100A1, PTEN, PRKCE, PYGM, RELA, PRKCD, RPS6KB1, HAND1, SLC8A1, PPARGC1A, MIR30B, MIR30A, MAP1LC3A, HAMP, AGTRAP, HDAC8, ATG16L1, TRPM4, ERRFI1, ANKRD1, SIRT1, ACOT2, POSTN, STAR, RAPGEF3, RAMP2, PARP2, TOMM70, ATG5, APLN, BECN1, OGT, YY1, VLDLR, TIMP4, TGFB1, PLAU, A2M, ATP5F1D, SLC25A4, MMP9, MMP2, MET, HAS1, LYN, LOXL1, ANXA5, HAS2, COX5B, RHOA, ATP1A2, AVPR1A, BAD, ITGA3, CD44, IL6, CD38, ANXA2, CYP11A1, MYC, EP300, PDGFRB, OPA1, NOS1, NME1, MTOR, CYP11B1, NDUFS3, HSF1, S1PR1, MYH6, GRK3, MYH7, PRKAG2, ABCC9, CDKN1C, SAMHD1, ESRRG, B3GAT3, CPT2, ELN, CLIC2, TREX1, FIG4, CPT1A, RNASEH2A, KCNQ1OT1, PEX7, SLC17A5, RNASEH2B, SPRY4-AS1, ACADM, ACTA2, ADAR, LINC02694, NHLRC2, H19, TAPT1, NEK9, RNASEH2C, GNPTAB, TBL2, IFIH1, ALPK3, PDSS2, HYMAI, FBN1, VAC14, BMP2, C1QBP, PAM16, COQ2, GTF2IRD1, FUCA1, FGF1, TGFBR2, TGFB3, FOXE3, JUP, KCNJ8, KCNQ1, LAMP2, SLC22A5, LBR, LIMK1, LOX, SMAD3, RFC2, MAT2A, RAF1, PSMB8, PRKG1, MYH11, MYLK, NAGA, PRKAR1A, NAGLU, NEU1, PLAGL1, TGFBR1, TGFB2, H19-ICR, CLIP2, IGF2, GTF2I, DYSF, HFE, MFAP5, CHST3, GAA, HEXB, TTR, HBB, GBA, PHYH, ZIC3, BAZ1B, ADM, SLC9A1, TNNI3, AKT3, PARP1, PPP3CB, NFATC4, HDAC4, GAB1, THRB, MAPK3, CYP11B2, CRP, LATS2, SCN5A, VCL, YWHAQ, VCAM1, MYOZ2, STK11, TP53, CAMK2D, ATXN7
-
Acute Stress Disorder
Wikipedia
Hans Selye was the first to coin the term "general adaptation syndrome" to suggest that stress-induced physiological responses proceed through the stages of alarm, resistance, and exhaustion. [6] The sympathetic branch of the autonomic nervous system gives rise to a specific set of physiological responses to physical or psychological stress. ... External links [ edit ] Classification D ICD - 10 : F43.0 ICD - 9-CM : 308 MeSH : D040701 v t e Emotions ( list ) Emotions Acceptance Adoration Aesthetic emotions Affection Agitation Agony Amusement Anger Angst Anguish Annoyance Anticipation Anxiety Apathy Arousal Attraction Awe Boredom Calmness Compassion Confidence Contempt Contentment Courage Cruelty Curiosity Defeat Depression Desire Despair Disappointment Disgust Distrust Ecstasy Embarrassment Vicarious Empathy Enthrallment Enthusiasm Envy Euphoria Excitement Fear Flow (psychology) Frustration Gratification Gratitude Greed Grief Guilt Happiness Hatred Hiraeth Homesickness Hope Horror Hostility Humiliation Hygge Hysteria Indulgence Infatuation Insecurity Inspiration Interest Irritation Isolation Jealousy Joy Kindness Loneliness Longing Love Limerence Lust Mono no aware Neglect Nostalgia Outrage Panic Passion Pity Self-pity Pleasure Pride Grandiosity Hubris Insult Vanity Rage Regret Social connection Rejection Remorse Resentment Sadness Melancholy Saudade Schadenfreude Sehnsucht Self-confidence Sentimentality Shame Shock Shyness Sorrow Spite Stress Suffering Surprise Sympathy Tenseness Trust Wonder Worry World views Cynicism Defeatism Nihilism Optimism Pessimism Reclusion Weltschmerz Related Affect consciousness in education measures in psychology Affective computing forecasting neuroscience science spectrum Affectivity positive negative Appeal to emotion Emotion and art and memory and music and sex classification evolution expressed functional accounts group homeostatic perception recognition in conversation in animals regulation interpersonal work Emotional aperture bias blackmail competence conflict contagion detachment dysregulation eating exhaustion expression intelligence and bullying intimacy isolation lability labor lateralization literacy prosody reasoning responsivity security selection symbiosis well-being Emotionality bounded Emotions and culture in decision-making in the workplace in virtual communication history moral self-conscious social social sharing sociology Feeling Gender and emotional expression Group affective tone Interactions between the emotional and executive brain systems Meta-emotion Pathognomy Pathos Social emotional development Stoic passions Theory affect appraisal discrete emotion somatic marker constructed emotion v t e Mental and behavioral disorders Adult personality and behavior Gender dysphoria Ego-dystonic sexual orientation Paraphilia Fetishism Voyeurism Sexual maturation disorder Sexual relationship disorder Other Factitious disorder Munchausen syndrome Intermittent explosive disorder Dermatillomania Kleptomania Pyromania Trichotillomania Personality disorder Childhood and learning Emotional and behavioral ADHD Conduct disorder ODD Emotional and behavioral disorders Separation anxiety disorder Movement disorders Stereotypic Social functioning DAD RAD Selective mutism Speech Stuttering Cluttering Tic disorder Tourette syndrome Intellectual disability X-linked intellectual disability Lujan–Fryns syndrome Psychological development ( developmental disabilities ) Pervasive Specific Mood (affective) Bipolar Bipolar I Bipolar II Bipolar NOS Cyclothymia Depression Atypical depression Dysthymia Major depressive disorder Melancholic depression Seasonal affective disorder Mania Neurological and symptomatic Autism spectrum Autism Asperger syndrome High-functioning autism PDD-NOS Savant syndrome Dementia AIDS dementia complex Alzheimer's disease Creutzfeldt–Jakob disease Frontotemporal dementia Huntington's disease Mild cognitive impairment Parkinson's disease Pick's disease Sundowning Vascular dementia Wandering Other Delirium Organic brain syndrome Post-concussion syndrome Neurotic , stress -related and somatoform Adjustment Adjustment disorder with depressed mood Anxiety Phobia Agoraphobia Social anxiety Social phobia Anthropophobia Specific social phobia Specific phobia Claustrophobia Other Generalized anxiety disorder OCD Panic attack Panic disorder Stress Acute stress reaction PTSD Dissociative Depersonalization disorder Dissociative identity disorder Fugue state Psychogenic amnesia Somatic symptom Body dysmorphic disorder Conversion disorder Ganser syndrome Globus pharyngis Psychogenic non-epileptic seizures False pregnancy Hypochondriasis Mass psychogenic illness Nosophobia Psychogenic pain Somatization disorder Physiological and physical behavior Eating Anorexia nervosa Bulimia nervosa Rumination syndrome Other specified feeding or eating disorder Nonorganic sleep Hypersomnia Insomnia Parasomnia Night terror Nightmare REM sleep behavior disorder Postnatal Postpartum depression Postpartum psychosis Sexual dysfunction Arousal Erectile dysfunction Female sexual arousal disorder Desire Hypersexuality Hypoactive sexual desire disorder Orgasm Anorgasmia Delayed ejaculation Premature ejaculation Sexual anhedonia Pain Nonorganic dyspareunia Nonorganic vaginismus Psychoactive substances, substance abuse and substance-related Drug overdose Intoxication Physical dependence Rebound effect Stimulant psychosis Substance dependence Withdrawal Schizophrenia , schizotypal and delusional Delusional Delusional disorder Folie à deux Psychosis and schizophrenia-like Brief reactive psychosis Schizoaffective disorder Schizophreniform disorder Schizophrenia Childhood schizophrenia Disorganized (hebephrenic) schizophrenia Paranoid schizophrenia Pseudoneurotic schizophrenia Simple-type schizophrenia Other Catatonia Symptoms and uncategorized Impulse control disorder Klüver–Bucy syndrome Psychomotor agitation Stereotypy
-
Pituitary Apoplexy
Wikipedia
Treatment of prolactinomas (pituitary adenomas that secrete prolactin ) with dopamine agonist drugs, as well as withdrawal of such treatment, has been reported to precipitate apoplexy. [1] [2] [4] Hemorrhage from a Rathke's cleft cyst , a remnant of Rathke's pouch that normally regresses after embryological development, may cause symptoms that are indistinguishable from pituitary apoplexy. [4] Pituitary apoplexy is regarded by some as distinct from Sheehan's syndrome , where the pituitary undergoes infarction as a result of prolonged very low blood pressure , particularly when caused by bleeding after childbirth . This condition usually occurs in the absence of a tumor. [4] Others regard Sheehan's syndrome as a form of pituitary apoplexy. [3] [9] Mechanism [ edit ] The pituitary gland is located in a recess in the skull base known as the sella turcica ("Turkish saddle", after its shape). ... External links [ edit ] Classification D ICD - 10 : E23.6 ICD - 9-CM : 253.8 MeSH : D010899 DiseasesDB : 10049 SNOMED CT : 237701005 External resources MedlinePlus : 001167 eMedicine : oph/471 Orphanet : 95613 v t e Pituitary disease Hyperpituitarism Anterior Acromegaly Hyperprolactinaemia Pituitary ACTH hypersecretion Posterior SIADH General Nelson's syndrome Hypophysitis Hypopituitarism Anterior Kallmann syndrome Growth hormone deficiency Hypoprolactinemia ACTH deficiency / Secondary adrenal insufficiency GnRH insensitivity FSH insensitivity LH/hCG insensitivity Posterior Neurogenic diabetes insipidus General Empty sella syndrome Pituitary apoplexy Sheehan's syndrome Lymphocytic hypophysitis Pituitary adenoma v t e Cardiovascular disease (vessels) Arteries , arterioles and capillaries Inflammation Arteritis Aortitis Buerger's disease Peripheral artery disease Arteriosclerosis Atherosclerosis Foam cell Fatty streak Atheroma Intermittent claudication Critical limb ischemia Monckeberg's arteriosclerosis Arteriolosclerosis Hyaline Hyperplastic Cholesterol LDL Oxycholesterol Trans fat Stenosis Carotid artery stenosis Renal artery stenosis Other Aortoiliac occlusive disease Degos disease Erythromelalgia Fibromuscular dysplasia Raynaud's phenomenon Aneurysm / dissection / pseudoaneurysm torso : Aortic aneurysm Abdominal aortic aneurysm Thoracic aortic aneurysm Aneurysm of sinus of Valsalva Aortic dissection Aortic rupture Coronary artery aneurysm head / neck Intracranial aneurysm Intracranial berry aneurysm Carotid artery dissection Vertebral artery dissection Familial aortic dissection Vascular malformation Arteriovenous fistula Arteriovenous malformation Telangiectasia Hereditary hemorrhagic telangiectasia Vascular nevus Cherry hemangioma Halo nevus Spider angioma Veins Inflammation Phlebitis Venous thrombosis / Thrombophlebitis primarily lower limb Deep vein thrombosis abdomen Hepatic veno-occlusive disease Budd–Chiari syndrome May–Thurner syndrome Portal vein thrombosis Renal vein thrombosis upper limb / torso Mondor's disease Paget–Schroetter disease head Cerebral venous sinus thrombosis Post-thrombotic syndrome Varicose veins Gastric varices Portacaval anastomosis Caput medusae Esophageal varices Hemorrhoid Varicocele Other Chronic venous insufficiency Chronic cerebrospinal venous insufficiency Superior vena cava syndrome Inferior vena cava syndrome Venous ulcer Arteries or veins Angiopathy Macroangiopathy Microangiopathy Embolism Pulmonary embolism Cholesterol embolism Paradoxical embolism Thrombosis Vasculitis Blood pressure Hypertension Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension Hypotension Orthostatic hypotension
-
Cryoglobulinemia
Wikipedia
The vascular deposition of these types of cryoglobulin-containing immune complexes and complement can cause a clinical syndrome of cutaneous small-vessel vasculitis characterized by systemic vasculitis and inflammation termed cryoglobulinemic vasculitis . [9] Accordingly, type II and type III cryoglobulinemic diseases are often grouped together and referred to as mixed cryoglobulinemia or mixed cryoglobulinemic disease. [8] The monoclonal IgM involved in Type I cryoglobulinemic diseases lacks rheumatoid factor activity. [9] More recent high resolution protein electrophoresis methods have detected a small monoclonal immunoglobulin component in type III cryoglobulins and/or a micro-heterogeneous composition of oligo-clonal (i.e., more than one monoclonal) immunoglobulin components or immunoglobulins with structures that do not fit into any classifications in the cryoglobulins of ≈10% of type II and III disease cases. It has been proposed that these cases be termed an intermediate type II-III variant of cryoglobulinemic disease and that some of the type III cases associated with the expression of low levels of a one or more isotypes of circulating monoclonal immunoglobulin(s) are in transition to type II disease. [7] [10] Signs and symptoms [ edit ] The clinical features of cryoglobulinemic disease can reflect those due not only to the circulation of cryoglobulins but also to any underlying hematological premalignant or malignant disorder, infectious disease, or autoimmune syndrome. The following sections of clinical features focuses on those attributed to the cryoglobulins. ... Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura , blue discoloration of the arms or legs (acrocyanosis) , necrosis, ulcers, and livedo reticularis ; spontaneous nose bleeds , joint pain , membranoproliferative glomerulonephritis ; and cardiovascular disturbances such as shortness of breath, inadequate levels of oxygen in the blood (hypoxemia) , and congestive heart failure . [2] [9] Types II and III cryoglobulinemic disease [ edit ] Types II and III (or mixed or variant) cryoglobulinemic disease may also present with symptoms and signs of blood hyperviscosity syndrome and deposition of cryoglobulins within blood vessels but also include those attributable to cryoglobulinemic vasculitis. " Meltzer's triad " of palpable purpura , joint pain , and generalized weakness occurs in ≈33% of patients presenting with type II or type III disease. One or more skin lesions including palpable purpura, ulcers, digital gangrene , and areas of necrosis occur in 69-89% of these mixed disease cases (see attached photograph); less common findings include painful peripheral neuropathy (often manifesting as mononeuritis multiplex in 19-44% of cases), kidney disease (primarily membranoproliferative glomerulonephritis (30%), joint pain (28%), and, less commonly, dry eye syndrome , Raynaud phenomenon (i.e., episodic painful reductions in blood flow to the fingers and toes). [9] [12] While the glomerulonephritis occurring in mixed disease appears to be due to inflammatory vasculitis, the glomerulonephritis occurring in type I disease appears due to the interruption of blood flow. [12] The hematological, infectious, and autoimmune diseases underlying type II cryoglobulinemic disease and the infectious and autoimmune diseases underlying type III cryoglobulinemic disease are also critical parts of the disease's clinical findings. ... "Prevalence of mixed cryoglobulinaemia syndrome and circulating cryoglobulins in a population-based survey: the Origgio study".
-
Macropsia
Wikipedia
Macropsia is related to other conditions dealing with visual perception , such as aniseikonia and Alice in Wonderland Syndrome ( AIWS , also known as Todd's syndrome). ... There is evidence that those who experience Alice in Wonderland Syndrome and associated macropsia are able to recount their experiences with thorough detail. ... Grune and Stratton; 1952. ^ Cinbis M, Aysun S: Alice in Wonderland syndrome as an initial manifestation of Epstein-Barr virus infection (case report). ... Abnormal magnetic resonance imaging in a child with Alice in Wonderland syndrome following Epstein-Barr virus infection No to hattatsu. Brain and development. 2002 Jul;34(4): 348-52 ^ a b Lahat E, et al. Alice in Wonderland syndrome and infectious mononucleosis in children.
-
Vasodilatory Shock
Wikipedia
If vasodilatory shock lasts more than a few minutes, the lack of oxygen starts to damage the body’s organs . [2] Vasodilatory shock like other types of shock should be treated quickly, otherwise it can cause permanent organ damage or death as a result of multiple organ dysfunction . [3] [4] [5] [6] Treatment typically involves uses of vasopressor , inotropes , fluid boluses , and introduction of resuscitation . [4] In case vasodilatory shock fails to respond to high doses of vasopressors (defined as ≥ 0.5 mg/kg/min norepinephrine-equivalent dose [7] ), meaning it's vasopressor-resistant and advances to being called refractory vasodilatory shock or simply refractory shock . [4] [8] Adjunctive therapies include angiotensin II , hydrocortisone , thiamine , catecolamines , ascorbic acid and combinations of thereof. [4] [9] [10] Contents 1 Signs and symptoms 2 Cause 3 Pathophysiology 4 Diagnosis 5 Management 6 Epidemiology 7 Prognosis 8 References Signs and symptoms [ edit ] See also: Cardiogenic shock § Signs and symptoms , Shock (circulatory) § Signs and symptoms , and Hypovolemic shock § Signs and symptoms Confusion or lack of alertness Loss of consciousness A sudden and ongoing rapid heartbeat Sweating Pale skin A weak pulse Rapid breathing Decreased or no urine output Cool hands and feet [3] Cause [ edit ] A bacterial infection in the bloodstream, [11] a severe allergic reaction ( anaphylaxis ), systemic inflammatory response syndrome , [12] or damage to the nervous system ( brain and nerves ) may cause vasodilatory shock. [3] [12] [13] Besides, nearly all kinds of distributive shock such as septic shock , neurogenic shock , anaphylactic shock , drug and toxin-induced shock , endocrine shock can turn out into rafractory vasodilatory shock when the original shock becomes more severe. [14] [2] [15] [16] [17] [4] The most common cause of vasodilatory shock is sepsis . [5] Except sepsis, other causes comprise severe acute pancreatitis , post cardiopulmonary bypass vasoplegia and other triggers for a systemic inflammatory response syndrome. [18] [19] [20] [21] Low serum calcium values might take a role in vasodilatory shock. [17] Pathophysiology [ edit ] In case of cardiogenic shock or acute hemorrhagic shock resulted from heart failure or from a large volume of blood loss , respectively, body deals with which by constricting peripheral vessels for the sake of reversing low arterial pressure that causes inadequate tissue perfusion. [22] Nevertheless, in vasodilatory shock, peripheral vascular smooth muscle finds it difficult to constrict. [22] In refractory vasodilatory shock, peripheral vascular smooth muscle even finds itself poorly respond to therapy with vasopressor drugs. [22] Vasopressin deficiency may play an important role in vasodilatory shock. [23] In refractory vasodilatory shock, the patient have both vasopressin secretion deficit as well as an advanced resistance to vasopressin-induced blood pressure changes. [23] Some hypothesized that patients with vasopressin deficiency including a decrease in baroreceptor stimulation appear to suffer from impaired autonomic reflexes. [23] They also argued that tonic may be inhibited by atrial stretch receptors and vasopressin release may be inhibited by nitric oxide or high circulating levels of norepinephrine . [23] Often, vasodilatory shock is contributed by the dysfunction of the physiologic compensatory mechanisms such as sympathetic nervous system , vasopressin arginine system , and the renin-angiotensin aldosterone system . [24] [5] [6] Diagnosis [ edit ] See also: Shock index The definition of refractory shock or vasodilatory shock varies. ... "The systemic inflammatory response syndrome following cardiac surgery: different expression of proinflammatory cytokines and procalcitonin in patients with and without multiorgan dysfunctions". ... "Systemic inflammatory response syndrome after cardiac surgery under cardiopulmonary bypass". ... PMID 29872882 . v t e Shock Distributive Septic shock Neurogenic shock Anaphylactic shock Toxic shock syndrome Obstructive Abdominal compartment syndrome Low volume Hemorrhage Hypovolemia Osmotic shock Other Spinal shock Cryptic shock Vasodilatory shock v t e Intensive care medicine Health science Medicine Medical specialities Respiratory therapy General terms Intensive care unit (ICU) Neonatal intensive care unit (NICU) Pediatric intensive care unit (PICU) Coronary care unit (CCU) Critical illness insurance Conditions Organ system failure Shock sequence SIRS Sepsis Severe sepsis Septic shock Multiple organ dysfunction syndrome Other shock Cardiogenic shock Distributive shock Anaphylaxis Obstructive shock Neurogenic shock Spinal shock Vasodilatory shock Organ failure Acute renal failure Acute respiratory distress syndrome Acute liver failure Respiratory failure Multiple organ dysfunction syndrome Neonatal infection Polytrauma Coma Complications Critical illness polyneuropathy / myopathy Critical illness–related corticosteroid insufficiency Decubitus ulcers Fungemia Stress hyperglycemia Stress ulcer Iatrogenesis Methicillin-resistant Staphylococcus aureus Oxygen toxicity Refeeding syndrome Ventilator-associated lung injury Ventilator-associated pneumonia Dialytrauma Diagnosis Arterial blood gas Catheter Arterial line Central venous catheter Pulmonary artery catheter Blood cultures Screening cultures Life-supporting treatments Airway management Chest tube Dialysis Enteral feeding Goal-directed therapy Induced coma Mechanical ventilation Therapeutic hypothermia Total parenteral nutrition Tracheal intubation Drugs Analgesics Antibiotics Antithrombotics Inotropes Intravenous fluids Neuromuscular-blocking drugs Recombinant activated protein C Sedatives Stress ulcer prevention drugs Vasopressors ICU scoring systems APACHE II Glasgow Coma Scale PIM2 SAPS II SAPS III SOFA Physiology Hemodynamics Hypotension Level of consciousness Acid–base imbalance Water-electrolyte imbalance Organisations Society of Critical Care Medicine Surviving Sepsis Campaign European Society of Paediatric and Neonatal Intensive Care Related specialties Anesthesiology Cardiology Internal medicine Neurology Pediatrics Pulmonology Surgery Traumatology
-
Iminoglycinuria
Wikipedia
"Glucoglycinuria, a new familial syndrome". The Journal of Pediatrics . 61 (3): 386–394. doi : 10.1016/S0022-3476(62)80369-2 . ... External links [ edit ] Classification D ICD - 10 : E72.0 ICD - 9-CM : 270.8 OMIM : 242600 MeSH : C536285 DiseasesDB : 6720 SNOMED CT : 84121007 External resources Orphanet : 42062 v t e Inborn error of amino acid metabolism K → acetyl-CoA Lysine /straight chain Glutaric acidemia type 1 type 2 Hyperlysinemia Pipecolic acidemia Saccharopinuria Leucine 3-hydroxy-3-methylglutaryl-CoA lyase deficiency 3-Methylcrotonyl-CoA carboxylase deficiency 3-Methylglutaconic aciduria 1 Isovaleric acidemia Maple syrup urine disease Tryptophan Hypertryptophanemia G G→ pyruvate → citrate Glycine D-Glyceric acidemia Glutathione synthetase deficiency Sarcosinemia Glycine → Creatine : GAMT deficiency Glycine encephalopathy G→ glutamate → α-ketoglutarate Histidine Carnosinemia Histidinemia Urocanic aciduria Proline Hyperprolinemia Prolidase deficiency Glutamate / glutamine SSADHD G→ propionyl-CoA → succinyl-CoA Valine Hypervalinemia Isobutyryl-CoA dehydrogenase deficiency Maple syrup urine disease Isoleucine 2-Methylbutyryl-CoA dehydrogenase deficiency Beta-ketothiolase deficiency Maple syrup urine disease Methionine Cystathioninuria Homocystinuria Hypermethioninemia General BC / OA Methylmalonic acidemia Methylmalonyl-CoA mutase deficiency Propionic acidemia G→ fumarate Phenylalanine / tyrosine Phenylketonuria 6-Pyruvoyltetrahydropterin synthase deficiency Tetrahydrobiopterin deficiency Tyrosinemia Alkaptonuria / Ochronosis Tyrosinemia type I Tyrosinemia type II Tyrosinemia type III / Hawkinsinuria Tyrosine → Melanin Albinism : Ocular albinism ( 1 ) Oculocutaneous albinism ( Hermansky–Pudlak syndrome ) Waardenburg syndrome Tyrosine → Norepinephrine Dopamine beta hydroxylase deficiency reverse: Brunner syndrome G→ oxaloacetate Urea cycle / Hyperammonemia ( arginine aspartate ) Argininemia Argininosuccinic aciduria Carbamoyl phosphate synthetase I deficiency Citrullinemia N-Acetylglutamate synthase deficiency Ornithine transcarbamylase deficiency / translocase deficiency Transport / IE of RTT Solute carrier family : Cystinuria Hartnup disease Iminoglycinuria Lysinuric protein intolerance Fanconi syndrome : Oculocerebrorenal syndrome Cystinosis Other 2-Hydroxyglutaric aciduria Aminoacylase 1 deficiency Ethylmalonic encephalopathy Fumarase deficiency Trimethylaminuria v t e Genetic disorder , membrane: Solute carrier disorders 1-10 SLC1A3 Episodic ataxia 6 SLC2A1 De Vivo disease SLC2A5 Fructose malabsorption SLC2A10 Arterial tortuosity syndrome SLC3A1 Cystinuria SLC4A1 Hereditary spherocytosis 4 / Hereditary elliptocytosis 4 SLC4A11 Congenital endothelial dystrophy type 2 Fuchs' dystrophy 4 SLC5A1 Glucose-galactose malabsorption SLC5A2 Renal glycosuria SLC5A5 Thyroid dyshormonogenesis type 1 SLC6A19 Hartnup disease SLC7A7 Lysinuric protein intolerance SLC7A9 Cystinuria 11-20 SLC11A1 Crohn's disease SLC12A3 Gitelman syndrome SLC16A1 HHF7 SLC16A2 Allan–Herndon–Dudley syndrome SLC17A5 Salla disease SLC17A8 DFNA25 21-40 SLC26A2 Multiple epiphyseal dysplasia 4 Achondrogenesis type 1B Recessive multiple epiphyseal dysplasia Atelosteogenesis, type II Diastrophic dysplasia SLC26A4 Pendred syndrome SLC35C1 CDOG 2C SLC39A4 Acrodermatitis enteropathica SLC40A1 African iron overload see also solute carrier family
-
Arteriovenous Malformation
Wikipedia
This question is currently being addressed in clinical trials. [32] See also [ edit ] Foix–Alajouanine syndrome Haemangioma Klippel–Trénaunay syndrome Parkes Weber syndrome References [ edit ] ^ "National Institute of Neurological Disorders and Stroke" . nih.gov . ... "Increased Prevalence of Aortic Stenosis in Patients With Arteriovenous Malformations of the Gastrointestinal Tract in Heyde Syndrome" . Archives of Internal Medicine . 163 (15): 1821–4. doi : 10.1001/archinte.163.15.1821 . ... September 26, 2018. ^ Research trials in arterio-venous malformations; Rustam Al-Shahi Salman Archived February 17, 2012, at the Wayback Machine Classification D ICD - 10 : Q27.3 , Q28.0 , Q28.2 , I77.0 , I25.4 ICD - 9-CM : 747.6 , 747.81 MeSH : D001165 DiseasesDB : 15235 External resources MedlinePlus : 000779 eMedicine : search/Arteriovenous%20Malformation v t e Congenital vascular defects / Vascular malformation Great arteries / other arteries Aorta Patent ductus arteriosus Coarctation of the aorta Interrupted aortic arch Double aortic arch Right-sided aortic arch Overriding aorta Aneurysm of sinus of Valsalva Vascular ring Pulmonary artery Pulmonary atresia Stenosis of pulmonary artery Subclavian artery Aberrant subclavian artery Umbilical artery Single umbilical artery Great veins Superior / inferior vena cava Congenital stenosis of vena cava Persistent left superior vena cava Pulmonary vein Anomalous pulmonary venous connection ( Total , Partial ) Scimitar syndrome Arteriovenous malformation Cerebral arteriovenous malformation v t e Cardiovascular disease (vessels) Arteries , arterioles and capillaries Inflammation Arteritis Aortitis Buerger's disease Peripheral artery disease Arteriosclerosis Atherosclerosis Foam cell Fatty streak Atheroma Intermittent claudication Critical limb ischemia Monckeberg's arteriosclerosis Arteriolosclerosis Hyaline Hyperplastic Cholesterol LDL Oxycholesterol Trans fat Stenosis Carotid artery stenosis Renal artery stenosis Other Aortoiliac occlusive disease Degos disease Erythromelalgia Fibromuscular dysplasia Raynaud's phenomenon Aneurysm / dissection / pseudoaneurysm torso : Aortic aneurysm Abdominal aortic aneurysm Thoracic aortic aneurysm Aneurysm of sinus of Valsalva Aortic dissection Aortic rupture Coronary artery aneurysm head / neck Intracranial aneurysm Intracranial berry aneurysm Carotid artery dissection Vertebral artery dissection Familial aortic dissection Vascular malformation Arteriovenous fistula Arteriovenous malformation Telangiectasia Hereditary hemorrhagic telangiectasia Vascular nevus Cherry hemangioma Halo nevus Spider angioma Veins Inflammation Phlebitis Venous thrombosis / Thrombophlebitis primarily lower limb Deep vein thrombosis abdomen Hepatic veno-occlusive disease Budd–Chiari syndrome May–Thurner syndrome Portal vein thrombosis Renal vein thrombosis upper limb / torso Mondor's disease Paget–Schroetter disease head Cerebral venous sinus thrombosis Post-thrombotic syndrome Varicose veins Gastric varices Portacaval anastomosis Caput medusae Esophageal varices Hemorrhoid Varicocele Other Chronic venous insufficiency Chronic cerebrospinal venous insufficiency Superior vena cava syndrome Inferior vena cava syndrome Venous ulcer Arteries or veins Angiopathy Macroangiopathy Microangiopathy Embolism Pulmonary embolism Cholesterol embolism Paradoxical embolism Thrombosis Vasculitis Blood pressure Hypertension Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension Hypotension Orthostatic hypotensionRASA1, AKT1, PTEN, PIK3CA, TEK, NOTCH1, FANCF, RFWD3, FANCI, ARHGAP31, FANCG, FANCE, FANCB, GUSB, FANCD2, FANCC, FANCA, DOCK6, FANCL, RBPJ, DLL4, MNX1, ERCC4, UBE2T, MAD2L2, ADAMTS3, XRCC2, VHL, VEGFA, RAD51, RAD51C, SLPI, FANCM, GNAQ, BRCA1, EOGT, ENG, CCBE1, FAT4, ACVRL1, PALB2, ARL6IP6, CBS, BRCA2, BRIP1, SLX4, SMAD4, IL6, TNF, KRAS, APOE, EPHB4, SMS, ANGPTL4, IL1B, GDF2, RSS, BRAF, ANGPT2, MAP2K1, MMP9, SOX17, PIK3CB, PIK3CD, PIK3CG, VWF, ANXA5, AGT, VCAM1, MMP3, MMP2, PART1, ICAM1, ELN, F3, EDN1, ACE, CLN3, CD6, SMG8, KDR, ABCA2, PAGE4, SYNGAP1, TGFB2, TGFB3, TGFBR1, THBS1, MIR137, SMUG1, TLR4, PDGFD, NES, COL18A1, CDKN2B-AS1, MIR210, PIK3R4, MIR195, KLF2, TMEM100, ESAM, BMP10, TGFB1, MVP, NOS1AP, MIR18A, PAGE1, BLNK, NOTCH3, STAT3, DLAT, MTOR, FN1, FLT1, FOXC2, FGF2, F2, ETS1, EPHB2, EFNB2, EFNA1, EDNRA, CRYAB, SPP1, COX8A, CDKN2A, CDH5, CD34, CCT, CASP3, VPS51, BDNF, ANPEP, ALX3, ALCAM, GJA5, HIF1A, HRAS, IFNG, SOX2, SNCA, SLC2A1, S100B, RBBP8, PTPN14, MAPK1, PLOD2, PECAM1, PDGFRB, PCYT1A, NOTCH4, ACTB, NOS3, NOS2, NOS1, MYB, MSH3, ABCC1, MGP, MDM4, MDM2, ITGB8, CERNA3
-
Chmp2b Frontotemporal Dementia
Gene_reviews
It typically starts between ages 46 and 65 years with subtle personality changes and slowly progressive behavioral changes, dysexecutive syndrome, dyscalculia, and language disturbances. ... Several individuals have developed an asymmetric akinetic rigid syndrome with arm and gait dystonia and pyramidal signs that may be related to treatment with neuroleptic drugs. ... Some individuals develop depressive symptoms early in the illness; they are typically mild. Manic syndromes have been observed in a few individuals. ... Four years into the illness, several individuals have developed a striking motor syndrome that develops into an asymmetric akinetic rigid syndrome with arm and gait dystonia and pyramidal signs. This syndrome may be related to treatment with neuroleptic drugs [Gydesen et al 2002, Brown et al 2004].
-
Flat Feet
Wikipedia
Navy special warfare trainees found no significant difference in the incidence of stress fractures among sailors and Marines with different arch heights. [25] See also [ edit ] Planovalgus deformity Marfan syndrome Ehlers-Danlos syndrome Comparison of orthotics References [ edit ] ^ a b Franco, Abby Herzog (1987). ... External links [ edit ] Can minimalist shoes help flat feet Natural flat feet solution the details Classification D ICD - 10 : M21.4 , Q66.5 ICD - 9-CM : 734 MeSH : D005413 DiseasesDB : 4852 External resources MedlinePlus : 001262 eMedicine : Orthoped/540 v t e Acquired musculoskeletal deformities Upper limb shoulder Winged scapula Adhesive capsulitis Rotator cuff tear Subacromial bursitis elbow Cubitus valgus Cubitus varus hand deformity Wrist drop Boutonniere deformity Swan neck deformity Mallet finger Lower limb hip Protrusio acetabuli Coxa valga Coxa vara leg Unequal leg length patella Luxating patella Chondromalacia patellae Patella baja Patella alta foot deformity Bunion/hallux valgus Hallux varus Hallux rigidus Hammer toe Foot drop Flat feet Club foot knee Genu recurvatum Head Cauliflower ear General terms Valgus deformity / Varus deformity Joint stiffness Ligamentous laxity v t e Congenital malformations and deformations of musculoskeletal system / musculoskeletal abnormality Appendicular limb / dysmelia Arms clavicle / shoulder Cleidocranial dysostosis Sprengel's deformity Wallis–Zieff–Goldblatt syndrome hand deformity Madelung's deformity Clinodactyly Oligodactyly Polydactyly Leg hip Hip dislocation / Hip dysplasia Upington disease Coxa valga Coxa vara knee Genu valgum Genu varum Genu recurvatum Discoid meniscus Congenital patellar dislocation Congenital knee dislocation foot deformity varus Club foot Pigeon toe valgus Flat feet Pes cavus Rocker bottom foot Hammer toe Either / both fingers and toes Polydactyly / Syndactyly Webbed toes Arachnodactyly Cenani–Lenz syndactylism Ectrodactyly Brachydactyly Stub thumb reduction deficits / limb Acheiropodia Ectromelia Phocomelia Amelia Hemimelia multiple joints Arthrogryposis Larsen syndrome RAPADILINO syndrome Axial Skull and face Craniosynostosis Scaphocephaly Oxycephaly Trigonocephaly Craniofacial dysostosis Crouzon syndrome Hypertelorism Hallermann–Streiff syndrome Treacher Collins syndrome other Macrocephaly Platybasia Craniodiaphyseal dysplasia Dolichocephaly Greig cephalopolysyndactyly syndrome Plagiocephaly Saddle nose Vertebral column Spinal curvature Scoliosis Klippel–Feil syndrome Spondylolisthesis Spina bifida occulta Sacralization Thoracic skeleton ribs : Cervical Bifid sternum : Pectus excavatum Pectus carinatum Authority control BNE : XX4422912 NDL : 00563110HOXD10, ELN, AUTS2, B4GALT7, EXOC6B, PHF8, IQSEC2, DHX30, CNKSR2, PUF60, AP4S1, ADNP, IL1RAPL1, PRDM5, MID2, TLK2, RAI1, STAG2, MED13L, AP4E1, RIN2, ATP6V0A2, FLRT3, FTSJ1, RAB3GAP2, NSMF, B3GAT3, BSCL2, TBL2, UBE2T, ANKRD11, GMPPB, ZDHHC9, RLIM, DACT1, AP4B1, ABL1, DEAF1, CCNK, AP4M1, AIFM1, BAZ1B, HERC1, FGF17, HESX1, CDK10, TRIP4, OFD1, CUL4B, USP9X, GDF5, GAN, MFAP5, CRLF1, EFTUD2, SEC23A, AMMECR1, MAD2L2, SEMA3A, ATP6AP2, HUWE1, SCO2, MED12, CUL7, LONP1, FRMPD4, GTF2IRD1, TBX4, CHST3, ARHGEF6, HS6ST1, DPM3, IL17RD, ALMS1, SLC9A7, C12orf57, STX1B, GORAB, RFT1, SLC39A13, ALG2, MYPN, CANT1, KISS1R, ZNF469, SLX4, ADGRV1, BRIP1, SPRTN, RAB39B, B3GALT6, PHIP, CCDC141, GDF6, USP27X, FEZF1, PTPRQ, HCN1, ZNF81, BRWD3, PROKR2, ALG14, ARX, VPS13B, PTCHD1, NDUFAF6, TANGO2, RAB33B, LAS1L, SPRY4, IARS2, FANCM, CHD8, SELENON, SALL4, HDAC8, WDR11, PACS1, TRIM8, CHD7, SLC29A3, FANCI, RFWD3, FANCL, FKBP14, WDR19, TRPV4, PROK2, PIEZO2, CXorf56, XYLT1, XYLT2, NSD1, SIL1, REEP1, UPF3B, PALB2, EHMT1, ALG13, PYROXD1, FBXO11, ASXL3, RAB7A, ZNF148, ACTA2, BPTF, FGF8, FGD1, FBN1, FANCG, FANCF, FANCB, ACSL4, FOXG1, FANCE, FANCD2, FANCC, FANCA, EXT2, ERCC4, FGFR1, FOXE3, GRM1, GABRG2, GRIA3, GLI3, GFPT1, GDI1, GATA4, GARS1, GABRD, FLI1, MTOR, FN1, FMR1, FLNB, FLNA, FLII, EP300, DUSP6, DPAGT1, ATR, CAPN1, CACNA1A, BRCA2, BRCA1, BCR, ATRX, ATP7A, DMD, ATP6V1E1, ATP6V1B2, AHCY, AGTR2, AGA, AEBP1, CTSC, CHAT, CLCN4, COL1A1, COL1A2, COL2A1, COL5A1, COL5A2, COL6A1, COL6A2, COL6A3, COL12A1, CPT2, CREBBP, CRKL, DCC, DLG3, GRIN2D, GTF2I, ZNF41, SCN2A, TACR3, SYP, SOX10, SLC16A2, SKI, SCN9A, SCN1B, TGFB1, SCN1A, SBF1, SARS1, SALL1, RYR1, RPS6KA3, TCF4, TGFB2, HCFC1, TTN, ZNF711, XRCC2, CLIP2, VLDLR, UCHL1, UBE2A, TRPS1, TGFB3, TRIO, TPM3, TPM2, TSPAN7, TGFBR2, TGFBR1, RFC2, CHCHD10, RAD51C, LMNA, MGAT2, MECP2, MAT2A, SMAD3, LOX, LMX1B, LIMK1, RAD51, LIFR, KIF22, KCNH1, ANOS1, HSPG2, HNRNPH2, MMP2, MYH7, MYH11, MYLK, NONO, PAK3, CHMP1A, PEX1, PEX6, PLOD1, PMM2, PRKG1, MAPK1, PTCH1, PURA, PYCR1, ALDH18A1, PDPN
-
Henoch–schönlein Purpura
Wikipedia
More than half also have proteinuria (protein in the urine), which in one eighth is severe enough to cause nephrotic syndrome (generalised swelling due to low protein content of the blood). ... PMID 10575422 . ^ Fauci AS (1987). "269:The Vasculitis Syndromes". In Braunwald E, Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS (eds.). ... "Henoch-Schönlein purpura in adulthood and childhood: two different expressions of the same syndrome" . Arthritis and Rheumatism . 40 (5): 859–64. doi : 10.1002/art.1780400513 . ... External links [ edit ] Classification D ICD - 10 : D69.0 ( ILDS D69.010) ICD - 9-CM : 287.0 MeSH : D011695 DiseasesDB : 5705 External resources MedlinePlus : 000425 eMedicine : derm/177 emerg/767 emerg/845 ped/3020 Wikimedia Commons has media related to Henoch–Schönlein purpura . v t e Hypersensitivity and autoimmune diseases Type I / allergy / atopy ( IgE ) Foreign Atopic eczema Allergic urticaria Allergic rhinitis (Hay fever) Allergic asthma Anaphylaxis Food allergy common allergies include: Milk Egg Peanut Tree nut Seafood Soy Wheat Penicillin allergy Autoimmune Eosinophilic esophagitis Type II / ADCC IgM IgG Foreign Hemolytic disease of the newborn Autoimmune Cytotoxic Autoimmune hemolytic anemia Immune thrombocytopenic purpura Bullous pemphigoid Pemphigus vulgaris Rheumatic fever Goodpasture syndrome Guillain–Barré syndrome " Type V "/ receptor Graves' disease Myasthenia gravis Pernicious anemia Type III ( Immune complex ) Foreign Henoch–Schönlein purpura Hypersensitivity vasculitis Reactive arthritis Farmer's lung Post-streptococcal glomerulonephritis Serum sickness Arthus reaction Autoimmune Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis Type IV / cell-mediated ( T cells ) Foreign Allergic contact dermatitis Mantoux test Autoimmune Diabetes mellitus type 1 Hashimoto's thyroiditis Multiple sclerosis Coeliac disease Giant-cell arteritis Postorgasmic illness syndrome Reactive arthritis GVHD Transfusion-associated graft versus host disease Unknown/ multiple Foreign Hypersensitivity pneumonitis Allergic bronchopulmonary aspergillosis Transplant rejection Latex allergy (I+IV) Autoimmune Sjögren syndrome Autoimmune hepatitis Autoimmune polyendocrine syndrome APS1 APS2 Autoimmune adrenalitis Systemic autoimmune disease v t e Systemic vasculitis Large vessel Takayasu's arteritis Giant cell arteritis Medium vessel Polyarteritis nodosa Kawasaki disease Thromboangiitis obliterans Small vessel Pauci-immune c-ANCA Granulomatosis with polyangiitis p-ANCA Eosinophilic granulomatosis with polyangiitis Microscopic polyangiitis Type III hypersensitivity Cutaneous small-vessel vasculitis IgA vasculitis Ungrouped Acute hemorrhagic edema of infancy Cryoglobulinemic vasculitis Bullous small vessel vasculitis Cutaneous small-vessel vasculitis Other Goodpasture syndrome Sneddon's syndromeC3, PLAU, SPAST, ATL1, KIF5A, MEFV, HLA-DRB1, HSP90B2P, SPG7, REEP1, SPG11, CYP7B1, ZFYVE26, CYP2U1, IGAN1, IGHA1, NIPA1, CXCL8, ACE, HSPD1, CAPN1, CRP, SPART, IL10, WASHC5, DDHD2, DDHD1, BSCL2, KIF1A, TFG, TNF, CCL2, FA2H, ERLIN2, PLP1, IL6, REN, NOS3, SOD1, PRDX5, MIF, VCP, HAVCR1, VEGFA, ALDH18A1, IL17A, KIF1B, PTHLH, MAD2L1BP, AGT, GBA2, PDXP, HSP90AA1, HLA-B, IL1B, IFT122, TLR4, PAX2, BICD2, ARL6IP1, SFXN1, RBM45, KIF1C, DNM2, CTLA4, CD28, CCL5, CPT1C, ATP13A2, SLC2A1, SLC33A1, IGFALS, PTPN22, SPG16, UBAP1, L1CAM, DNM1L, ARHGEF5, TIMELESS, AP5Z1, ITPR1, PLA2G6, SPG27, ABCB6, TECPR2, WG, FARS2, AP4B1, MIR33A, TUBB4A, HT, DNAJB1P1, C9orf72, LRPPRC, PNPLA6, IL18BP, CIC, AFG3L2, ZFYVE27, MMP26, ATAD3A, REEP2, C1GALT1, HSPA14, SCYL1, SEC24D, ICOS, NAAA, ALS2, CXCL16, POU2F3, IL21, PLD3, DAPK2, TARDBP, KIF13B, UBA5, RNF170, PITPNM3, DPY30, HAVCR2, IL17F, IL22, ASIC2, ASIC3, FXN, GATA3, GPT, GRM1, HLA-A, HMGB1, HSPA1A, HSPA1B, HSPA2, HSPA4, DNAJB1, ICAM1, IFNG, IL1A, IL1RN, IL6R, B4GALNT1, FCGRT, AP4M1, FAT2, AGTR1, ALB, ATP1A1, BCL2, BCL6, CXCR5, C5AR1, CFTR, COL4A5, CRMP1, CSK, DNMT1, EPHB2, ESR1, F2, IL6ST, IL18, CXCL10, ITGB2, RNF6, ATXN2, CXCL5, CX3CL1, SLC1A2, PARP1, SPTAN1, TIMP4, TLR2, TP53, SCGB1A1, UTRN, XRCC1, DENR, DLEU2, MAPK3, MAPK1, PON1, ATXN3, KCNA2, KIF5B, KIF5C, KRT10, MBL2, MGAT5, MMP3, PF4, MMP9, MTHFR, TRNT, NEFL, NM, NOS2, SPG36
-
Ltbp4-Related Cutis Laxa
Gene_reviews
The phenotypic spectrum of ATP6V0A2 -related cutis laxa includes Debré-type cutis laxa at the severe end and wrinkly skin syndrome at the mild end. Affected individuals have furrowing and premature wrinkling of the skin of the entire body that improves with time. ... Patients who additionally have corneal clouding due to ruptures in Descemet’s membrane or cataracts are considered to have ARCL3B (de Barsy syndrome B) [Reversade et al 2009, Dimopoulou et al 2013]. ... Autosomal recessive cutis laxa type 3A (ARCL3A, de Barsy syndrome A) (OMIM 219150) is similar to ARCL3B, but is usually situated at the most severe end of the type 3 recessive cutis laxa spectrum with severe IUGR, a progeroid appearance with a thin skin and visible veins, adducted thumbs, and corneal clouding and/or cataract. ... Both mutation of GORAB [Hennies et al 2008] and PYCR1 [Yildirim et al 2011] have been described. Occipital horn syndrome (OHS) (sometimes referred to as X-linked cutis laxa [XLCL]) is characterized by "occipital horns," distinctive wedge-shaped exostoses at the sites of attachment of the trapezius muscle and the sternocleidomastoid muscle to the occipital bone. ... Macrocephaly, alopecia, cutis laxa, scoliosis (MACS) syndrome (also known as RIN2 syndrome) (OMIM 613075) is an autosomal recessive disorder that includes the eponymous clinical manifestations as well as progressive facial coarsening, gingival hyperplasia, and skin and joint laxity.
-
Optic Neuritis
Wikipedia
External links [ edit ] Classification D ICD - 10 : H46 , G44.848 ICD - 9-CM : 377.30 MeSH : D009902 DiseasesDB : 9242 External resources MedlinePlus : 000741 eMedicine : radio/488 v t e Diseases of the human eye Adnexa Eyelid Inflammation Stye Chalazion Blepharitis Entropion Ectropion Lagophthalmos Blepharochalasis Ptosis Blepharophimosis Xanthelasma Ankyloblepharon Eyelash Trichiasis Madarosis Lacrimal apparatus Dacryoadenitis Epiphora Dacryocystitis Xerophthalmia Orbit Exophthalmos Enophthalmos Orbital cellulitis Orbital lymphoma Periorbital cellulitis Conjunctiva Conjunctivitis allergic Pterygium Pseudopterygium Pinguecula Subconjunctival hemorrhage Globe Fibrous tunic Sclera Scleritis Episcleritis Cornea Keratitis herpetic acanthamoebic fungal Exposure Photokeratitis Corneal ulcer Thygeson's superficial punctate keratopathy Corneal dystrophy Fuchs' Meesmann Corneal ectasia Keratoconus Pellucid marginal degeneration Keratoglobus Terrien's marginal degeneration Post-LASIK ectasia Keratoconjunctivitis sicca Corneal opacity Corneal neovascularization Kayser–Fleischer ring Haab's striae Arcus senilis Band keratopathy Vascular tunic Iris Ciliary body Uveitis Intermediate uveitis Hyphema Rubeosis iridis Persistent pupillary membrane Iridodialysis Synechia Choroid Choroideremia Choroiditis Chorioretinitis Lens Cataract Congenital cataract Childhood cataract Aphakia Ectopia lentis Retina Retinitis Chorioretinitis Cytomegalovirus retinitis Retinal detachment Retinoschisis Ocular ischemic syndrome / Central retinal vein occlusion Central retinal artery occlusion Branch retinal artery occlusion Retinopathy diabetic hypertensive Purtscher's of prematurity Bietti's crystalline dystrophy Coats' disease Sickle cell Macular degeneration Retinitis pigmentosa Retinal haemorrhage Central serous retinopathy Macular edema Epiretinal membrane (Macular pucker) Vitelliform macular dystrophy Leber's congenital amaurosis Birdshot chorioretinopathy Other Glaucoma / Ocular hypertension / Primary juvenile glaucoma Floater Leber's hereditary optic neuropathy Red eye Globe rupture Keratomycosis Phthisis bulbi Persistent fetal vasculature / Persistent hyperplastic primary vitreous Persistent tunica vasculosa lentis Familial exudative vitreoretinopathy Pathways Optic nerve Optic disc Optic neuritis optic papillitis Papilledema Foster Kennedy syndrome Optic atrophy Optic disc drusen Optic neuropathy Ischemic anterior (AION) posterior (PION) Kjer's Leber's hereditary Toxic and nutritional Strabismus Extraocular muscles Binocular vision Accommodation Paralytic strabismus Ophthalmoparesis Chronic progressive external ophthalmoplegia Kearns–Sayre syndrome palsies Oculomotor (III) Fourth-nerve (IV) Sixth-nerve (VI) Other strabismus Esotropia / Exotropia Hypertropia Heterophoria Esophoria Exophoria Cyclotropia Brown's syndrome Duane syndrome Other binocular Conjugate gaze palsy Convergence insufficiency Internuclear ophthalmoplegia One and a half syndrome Refraction Refractive error Hyperopia Myopia Astigmatism Anisometropia / Aniseikonia Presbyopia Vision disorders Blindness Amblyopia Leber's congenital amaurosis Diplopia Scotoma Color blindness Achromatopsia Dichromacy Monochromacy Nyctalopia Oguchi disease Blindness / Vision loss / Visual impairment Anopsia Hemianopsia binasal bitemporal homonymous Quadrantanopia subjective Asthenopia Hemeralopia Photophobia Scintillating scotoma Pupil Anisocoria Argyll Robertson pupil Marcus Gunn pupil Adie syndrome Miosis Mydriasis Cycloplegia Parinaud's syndrome Other Nystagmus Childhood blindness Infections Trachoma Onchocerciasis v t e Headache Primary ICHD 1 Migraine Familial hemiplegic Retinal migraine ICHD 2 Tension Mixed tension migraine ICHD 3 Cluster Chronic paroxysmal hemicrania SUNCT ICHD 4 Hemicrania continua Thunderclap headache Sexual headache New daily persistent headache Hypnic headache Secondary ICHD 5 Migralepsy ICHD 7 Ictal headache Post-dural-puncture headache ICHD 8 Hangover Medication overuse headache ICHD 13 Trigeminal neuralgia Occipital neuralgia External compression headache Cold-stimulus headache Optic neuritis Postherpetic neuralgia Tolosa–Hunt syndrome Other VascularMOG, CAPN1, AQP4, TK2, POLG, PLXNA2, TNF, CSF2, LAMC2, HLA-DRB1, ASCC2, PMEL, MBP, SART3, IL10, IL4, IFNG, HLA-DRB5, CD19, HLA-DQB1, CAT, TPX2, HCRT, SND1, NFKB2, OAS3, CUX1, HT, SDC1, REN, STAT1, OPN1LW, TG, IL27, PRKCD, CXCL13, TPO, PHLDA2, PLA2G6, RBM45, RTN4R, MLC1, POU2F3, RASL12, RASD1, IL17D, LINGO1, DPYSL5, APOE, MS, PLA2G2A, HLA-A, AVPR2, BDNF, CD14, CD27, CISH, CCR5, CNR1, EDN1, GABPA, GFAP, GSTM1, GSTT1, HLA-DQA1, PLA2G1B, IL17A, ITGB3, MAG, MAP3K5, MIF, MMP2, MMP9, FAS, NEFH, NEFL, NFE2L2, CLDN11, MARCHF11
-
Kidney Disease
Wikipedia
Nephritis and nephrosis can give rise to nephritic syndrome and nephrotic syndrome respectively. ... It is characterized by nephrotic syndrome and diffuse scarring of the glomeruli . ... External links [ edit ] Classification D ICD - 10 : N00 - N29 MeSH : D007674 v t e Kidney disease Glomerular disease See Template:Glomerular disease Tubules Renal tubular acidosis proximal distal Acute tubular necrosis Genetic Fanconi syndrome Bartter syndrome Gitelman syndrome Liddle's syndrome Interstitium Interstitial nephritis Pyelonephritis Balkan endemic nephropathy Vascular Renal artery stenosis Renal ischemia Hypertensive nephropathy Renovascular hypertension Renal cortical necrosis General syndromes Nephritis Nephrosis Renal failure Acute renal failure Chronic kidney disease Uremia Other Analgesic nephropathy Renal osteodystrophy Nephroptosis Abderhalden–Kaufmann–Lignac syndrome Diabetes insipidus Nephrogenic Renal papilla Renal papillary necrosis Major calyx / pelvis Hydronephrosis Pyonephrosis Reflux nephropathyUMOD, AGTR1, B2M, TTC21B, RPGRIP1L, TREX1, EDN1, ALB, KL, NFE2L2, FGA, AGT, REN, LCN2, EPO, TGFB1, MTHFR, ACE, CST3, IGF1, NPHS1, MPO, IL1RN, HAVCR1, PTGS2, SOD2, SPP1, COL4A1, WNK1, FGF2, SLC12A3, SPARC, NOS2, PPARA, LRP2, EGF, CASP1, ACKR3, MIR21, THG1L, ANXA1, IL33, GLIS2, WNT4, CYP2C8, SV2B, CYP3A5, FABP4, PYCARD, GSTP1, CYBB, CLU, SLC7A9, HNF1A, PARP1, MIR192, MXI1, LEPR, NQO1, RRM2B, CCL2, SLC22A2, RBP4, SMPD1, CALB1, TRPC6, ALAD, MT4, RASAL1, CNNM2, CTSD, SLC47A1, IFT122, PCSK5, NPR1, MMP9, HOXD11, HOXA11, SIX2, NR4A1, NEK8, POMC, TERT, TFAP2A, TFF3, CSF3, CDKN1A, ACTA2, THAS, CTF1, GATM, ADRA1B, RGN, ADRB2, CCL5, ABCB1, BMP7, CASP9, XYLT1, TGFBI, TGFBR2, MIF, G6PD, CASP3, RAMP2, CASP8, CFH, NLRP3, CYGB, SREBF2, ABCC3, SREBF1, RELB, MKI67, MYH9, PPP3CA, TGFBR1, LMX1B, PPARG, WT1, INS, GLA, TTR, APOA1, LYZ, MEFV, HNF4A, CD151, EIF2AK3, FOS, IFT140, TMEM67, SCNN1G, CEP290, WDR73, CLDN19, FAM20A, NPHP1, GCK, ABCC8, SCNN1A, SCARB2, CCND1, WFS1, BLK, PAFAH1B1, VPS33B, SIRT1, PAX4, FOXI1, INPP5E, SERPINE1, MAFB, ALG1, LAGE3, PRDX1, CISD2, WAS, ZNF423, NUP133, BSCL2, CFHR5, SAA1, VEGFA, IL6, SCNN1B, WDR34, IL10, WDR60, KLF11, DPP4, SLC26A4, OSGEP, TP53RK, DYNC2H1, MMACHC, ACE2, IGAN1, VIPAS39, HLA-DPB2, PKD2, WDR19, NOD2, NPHS2, PKD1, RAPGEF5, FGF23, HPRT1, APPL1, IFT80, CC2D2A, TMEM237, YWHAE, NUP107, WIPF1, IFT172, PRODH, PSMB8, GABPA, APOE, TMEM231, PTH, PDX1, HIC1, NOS3, TPRKB, SLC5A2, NEUROD1, TNF, ADA2, DYNC2LI1, AGPAT2, HORMAD2, TMEM138, MUC1, CCN2, CEP120, KCNJ10, WDR4, CEL, CAVIN1, HNF1B, COL7A1, COL4A5, COL4A3, ACTN4, SEC61A1, NR3C2, KCNJ11, TMEM216, CAV1, APOL1, AKR1B1, ADIPOQ, CRP, IL1B, ADM, POSTN, CNDP1, GCG, IL17A, GLP1R, LGALS3, AGER, EHMT1, ELMO1, ESR1, ACTB, VDR, TLR4, HIF1A, SLC2A1, STAT3, MTOR, HLA-DRB1, ZGLP1, RAC1, COL4A4, LEP, LPA, CAT, PLG, CABIN1, CCR5, EGFR, HMOX1, CTNNB1, FN1, DECR1, TNFRSF1A, PON1, PGR-AS1, CD2AP, TP53, TRPC5, KEAP1, GH1, INF2, PSMD9, CCR2, SOD1, FGF21, ANGPT2, ATP6AP2, BCL2, RENBP, NFKB1, COQ8B, IGHA1, TM7SF2, ANGPT1, VPS51, G6PC, GPBAR1, ABO, KLK1, IL4, HAMP, CXCL10, PKHD1, HGF, ACACB, IL1A, SMAD3, SLC33A1, MPV17, KLK4, GDF15, PAX2, HP, SMARCAL1, MBL2, IL18, NPPB, SMAD7, CXCL8, ADAM17, MMP2, PRKCB, SLC2A2, DCN, CYBA, IQCB1, DDR1, EDNRA, TXN, SCGB1A1, MOK, AVP, ATM, PCSK9, PRKD1, THBS1, GORASP1, TLR2, CYP24A1, TIMP1, RBM45, SLC4A1, RTN1, DIANPH, PODXL, MIR155, AHI1, MMP7, SGK1, GPX3, UTS2, EGR1, TSC2, SYNPO, GSTM1, TNFRSF12A, PPARGC1A, SYT1, SDC2, HLA-DQA1, SELL, COQ2, CCN3, KDR, SLC9C1, HSPG2, FABP1, GJA1, ACR, CUBN, CLDN16, COL4A6, MAPK8, MAP3K5, KLF15, CLCN5, TMSB4X, APOC3, ADD1, DKK3, ERAL1, FOXO1, OGA, HIPK2, IL22, TLR9, HMGB1, APOM, MYO1E, RELA, AGTR2, MYH2, ADAM19, KLF4, ARTN, CXCR6, LPAR2, COX1, SSTR4, COX2, TCF7L2, TGFA, NAGLU, ANGPTL3, XPR1, MTRR, HPSE, TIMP2, TNFSF13B, TNFSF13, SOAT1, GADD45G, PLA2G1B, NCF2, ANP32B, LOH19CR1, HDAC6, NR1H4, VWF, CNTN3, NEDD4L, SIRT3, MLYCD, ENPP1, SERPINF1, HMGA2, MAPK3, DDAH1, PRKAB1, PRKAA2, PRKAA1, CADM1, CXCR4, MANF, RNU1-4, SLC17A5, P2RX7, NPPA, SLC12A1, IRS2, SOCS1, NGF, NOTCH1, NOTCH3, TNFRSF1B, DGKE, TSC1, RPS6KA1, VCAM1, SLC11A2, CUL3, ULK1, SCN7A, SCD, NTRK1, RPS19, CXCL12, MAP3K14, SETD2, RETN, FAT1, MIR214, C3, FCGRT, BTK, FOXC1, FLI1, NOX5, BRS3, CRELD2, GATA3, AGXT2, GHR, HHIP, BDNF, CXCR3, UTS2R, GPR42, BDKRB1, HBA1, HFE, STS, ARSA, HSD11B2, PDSS2, CAD, CALD1, SLC19A3, NPHP4, CTLA4, CP, CTNS, COX8A, CTSL, CX3CR1, THSD7A, FRMD3, CYP2E1, CYP3A4, COPD, CLCNKB, MIR182, IFNL3, AQP11, CFTR, GOLGA6A, CDC42, ENO1, CD40, CD80, MS4A1, CD14, CASR, HSPA9, BGN, MAPK14, ADRA2B, AFM, IHG1, IL2, RCBTB1, AGRP, AHSG, ILK, IDO1, INSR, APEX1, SIRT6, AMBP, ITGAM, ALPL, NBAS, JAG1, ICAM1, KNG1, AKT1, KRT20, AHR, IGHG3, TREM1, ADRA1A, IGFBP7, MTCO2P12, NOX4, LINC01672, FAS, IFNG, ADAM10, MGP, NOG, MIR141, MTHFS, CCT2, H3P10, MIR10A, SLC19A2, MIR145, SLC22A6, PKD2L1, MIRLET7C, MASP2, CAPN9, PRSS55, MIR146A, MIR150, SLC7A7, SUMO4, AHSA1, STON1-GTF2A1L, IFNL1, H3P23, OR10A4, DCTN6, COX7A2L, PDPN, SPESP1, CRB2, TXNIP, CD163, HCAR2, FCGR2C, NRK, TBX18, SH2B2, TICAM2, GSTK1, CTCF, MIF-AS1, MIR1207, MIR191, BMS1, AIM2, MAGI2, HNP1, MIR146B, NPS, DELYQ11, ARHGEF11, NCF1, SPATA2, MIR618, KLRC4-KLRK1, RPL17-C18orf32, MIR377, MIR802, KTWS, SOD2-OT1, CD24, MFT2, TMED7-TICAM2, MIR1915, CLOCK, PTGES, TBPL1, MIR1249, COMMD3-BMI1, ARID2, UBD, GDF11, ZNRD2, UNC13B, NSA2, SIRT1-AS, MIR19B1, SLC22A8, GRAP2, CORO2B, KLF2, MIR216A, AD17, FADS2, MIR375, CELA3A, NAMPT, MIR99B, TRAP1, MIR148B, MIR4490, ABCB6, HDAC5, MIR151A, MIR373, NTN1, MIR200A, C1QTNF1, NES, SEMA3G, ZNF410, TRIB3, EPB41L5, USP36, GOPC, POLDIP2, C1GALT1, CHMP2B, PTPN22, CLEC4E, ANKS1B, SUCNR1, SLC2A9, CCL28, TP53INP2, SOSTDC1, BBS12, LY96, PSD4, DDAH2, COLEC11, SMURF2, DDX58, MPP5, ABCG8, RNF19A, IFIH1, XYLT2, TNMD, XPNPEP3, UBE2O, ELOVL5, ZC4H2, CNDP2, FAR2, SOST, SNX9, NOSIP, TMED7, SMPDL3B, DERL2, ASCC1, SGSM3, RNLS, TAS2R13, MBL3P, RGCC, COMMD5, NXPH1, ICOS, IL23A, GPRC5B, GNMT, IL17C, ANLN, IL37, CCHCR1, PALD1, INVS, FBLIM1, MKS1, NAT8, NOX1, TESC, FOXD3, MOCOS, BBS7, MMD, EFHD2, BHLHE41, CCDC114, STON1, SGF29, PRRT2, TREH, MYOCD, CHEK2, DNER, VASH1, RSAD2, GPR182, PHB2, LRSAM1, MCU, ABCC11, GTF2A1L, SORCS1, C1GALT1C1, VASN, KCNQ1OT1, IL17RE, MAPRE2, SLCO6A1, FERMT2, MAGED2, SIRPA, PTPRVP, PLB1, ZSWIM2, CFHR3, SDCCAG8, HFM1, TDGF1P6, HAVCR2, TNFRSF13B, STAB1, PDGFD, ITPKC, MCF2L2, DDN, KDM6B, TBC1D9, ALPK1, SPZ1, BICC1, JADE1, VTCN1, NLRX1, BRD4, CEP97, WNT10A, CMIP, MYO16, PALLD, APOL4, PLA2R1, MAPRE1, KLRK1, APOL3, SETD7, ARHGAP24, HMCN1, SACM1L, MINDY4, NLRP1, WDR83, NT5C1A, ABCA1, RSC1A1, SOCS3, FABP2, PTK2B, FCGR2A, FCGR2B, FGF13, FGG, FGL1, FOXC2, FLII, FLT1, FMOD, FOSB, FOSL2, GAST, SLC37A4, GAD1, GAD2, GAS1, GC, GCKR, GEM, GFPT1, ACSL1, F10, GLO1, F5, DUSP5, EDA, EDNRB, EFNB1, EFNB2, CELA1, ELAVL1, ENG, ENO2, STX2, ERBB4, ERCC1, ERCC4, ESRRA, ESRRG, ETFA, ETS1, EYA1, F2, F2R, F3, GCLC, GNAO1, INPP5D, HES1, HSPA1B, HSPA4, HSPA5, HSP90AA1, NDST1, HTC2, ID1, CFI, IFI27, IFN1@, IFNA1, IFNA13, IFNAR1, IFNB1, IGFBP1, IGFBP3, IL1R1, IL2RA, IL7R, IL9, CXCR2, HSPA1A, PRMT1, GNB3, HRES1, GOLGB1, GPT, GPX4, GRP, GSK3B, GSN, GSTT1, GUCA2A, GUCA2B, HAS2, HAS3, HDAC1, HDAC2, CFHR1, HLA-C, HLA-DPA1, HLA-DQB1, HLA-DQB2, HLA-E, HPS1, HPT, HBEGF, RCAN1, ATN1, SERPINC1, ATIC, ATR, BCL3, BGLAP, BLVRA, BMI1, DST, BRAF, BSG, BTF3P11, C3AR1, C5, C5AR1, CA1, CA2, CALR, CAMK4, CARS1, CAV2, RUNX2, CD5L, ATF4, ARSL, DRD3, ARRB1, ACACA, ADCYAP1, ADD3, ALOX12, ALOX5, AMH, SLC25A4, APOA4, APOB, APOC1, APRT, KLK3, AQP1, AQP2, AQP4, AQP5, AQP6, AREG, ARF6, ARG2, ARNTL, CD28, CD34, CD36, CD40LG, CSF1, CSH1, CSH2, VCAN, CTSB, CYLD, CYP2A6, CYP2B6, CYP2C19, CYP2C9, CYP19A1, CYP27B1, DAB2, DAO, DBH, DDIT3, DDOST, DES, DIAPH1, DMRT1, DNASE2, CRK, CR2, MAP3K8, CHGA, CDH5, CDH13, CDK4, CDK9, CDKN1C, CDKN2A, CEBPB, CETP, CFL1, CHI3L1, COL11A2, CHIT1, CISH, ERCC8, CLC, CMA1, CCR3, ABCC2, CNR1, COL4A2, INHBC, IRF5, HAP1, SRC, SSBP1, SST, ST2, STAT4, STATH, SULT1E1, TAC1, TAGLN, TBX3, TRBV20OR9-2, TFRC, TGFB2, THBD, THBS2, THY1, TIMP3, TLR3, NR2E1, TPM3, CRISP2, TRPC1, TRIM21, SP3, TWIST1, SOX2, SALL1, SCT, SRL, CCL7, CCL21, SDC1, SDC4, SELE, SFRP1, SFTPD, SHBG, SKP2, SLC5A1, SLC9A3, SLC15A2, SMARCB1, SIGLEC1, SNCA, SNRPD1, SOD3, SORD, TRPC3, TNFSF4, ITGA2, NR4A3, MKKS, PLA2G6, BBOX1, ITGA8, AP3B1, RUVBL1, AOC3, KCNK5, VAMP8, MBTPS1, TNFSF10, TNFRSF6B, NRP2, NRP1, KAT2B, PROZ, LDB1, PER2, ARHGEF7, SELENBP1, PGLYRP1, SLC25A16, AIMP2, TNFRSF4, RNF217-AS1, TYRO3, TYROBP, TYRP1, UCHL1, UGT2B17, KDM6A, VASP, VEGFC, VHL, EZR, VIM, TRPV1, VTN, WNT9A, XDH, YWHAZ, ZFP36, ZNF236, ALMS1, TFEB, PUJO, S100A8, RPL17, RPL10, LPL, LTF, SMAD2, MAS1, MCL1, CD46, SMCP, MDH2, MDM2, MFAP1, CXCL9, MLN, KMT2A, MME, MMP10, MMP14, MS, MST1R, ATP6, COX3, ND5, TRNT, LTA, LOXL2, ROS1, LMNA, ITGB1, ITGB2, JUN, JUNB, JUND, KCNE1, KCNQ1, KIR2DS1, KIR2DS3, KIR3DL1, KIR3DS1, KIT, KRAS, LAMA5, LAMB2, LCAT, LDLR, LECT2, LGALS1, LIMS1, LIPC, MYBPH, NCAM1, NDN, NFYA, PRKCA, MAPK1, MAP2K7, PROC, PSMA6, PTEN, PTGDS, PTGS1, PTK2, PTPRC, PTX3, PVR, RAB4A, RAG1, RARA, RARRES2, PLAAT4, REG1A, RFC1, RMRP, RNASE2, PRD, PPIA, PON2, PC, NGFR, NOS1, NPY, NOTCH2, NOTCH4, YBX1, TNFRSF11B, PAEP, PAH, PCBD1, PLXNA1, PCNA, PDCD1, PF4, CFP, PIK3CG, PLA2G2A, PLAT, PLAU, PLAUR, H3P40