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Bone Cancer
Mayo_clinic
Risk factors It's not clear what causes bone cancer, but doctors have found certain factors are associated with an increased risk, including: Inherited genetic syndromes. Certain rare genetic syndromes passed through families increase the risk of bone cancer, including Li-Fraumeni syndrome and hereditary retinoblastoma.PLOD2, PLAU, TGFBR2, BAP1, NCOA3, PTGS2, MMP2, MMP9, OPRM1, TNF, SIRT1, CNR2, EWSR1, P2RX7, FOXP1, HDAC9, TLR3, GDNF, MTOR, ESR1, CASP3, TRPV1, IL6, PIK3CD, TP53, PENK, PIK3CA, PIK3CB, PIK3CG, VEGFA, SMC3, SOCS3, GPR65, VSNL1, CXCR4, NR1H2, TNFRSF1A, VDAC1, ASIC3, UCN, CXCL13, SLIT2, TRIM14, MIR486-1, BDNF-AS, MIR34A, MIR217, MIR145, GADL1, SGMS2, FSIP1, OSR1, CHDM, AZIN2, PRRT2, CD276, SUV39H2, WNK1, SLC12A5, NMUR2, TRAT1, SMUG1, CRTC1, ARC, RHOBTB2, MCF2L2, SYNPO, MGLL, SPP1, BCL2L11, STAT1, GRK2, SOD1, GJA1, GFAP, ERG, EPHB2, EPHB1, EPHA3, ENG, EGFR, DRD2, DPEP1, DNMT3A, DLG3, CTLA4, CSF2, CRH, CHRM3, CDKN2A, CD38, RUNX2, TSPO, BSG, BMP2, BMI1, CXCR5, GH1, GRIN2B, CXCL12, GRM1, ROCK1, ROBO1, REST, MAPK1, PRKCB, PRKCA, BDNF, P2RX3, OPRK1, MTAP, LRP2, KDR, KCNA2, JAK2, ITGAV, IL18, IL10, IL1B, HMGB1, HLA-DOA, HDAC2, HDAC1, GRM5, COMMD3-BMI1
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Raynaud's Disease
Mayo_clinic
Other names for this condition are: Raynaud's phenomenon. Raynaud syndrome. Women are more likely than men to have Raynaud's disease. ... Other diseases that increase the risk of Raynaud's include lupus, rheumatoid arthritis and Sjogren's syndrome. Diseases of the arteries. These include a buildup of fatty deposits in blood vessels that feed the heart and a disorder in which the blood vessels of the hands and feet become inflamed. A type of high blood pressure that affects the arteries of the lungs also may cause secondary Raynaud's. Carpal tunnel syndrome. This condition involves pressure on a major nerve to the hand.
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Infantile Sialic Acid Storage Disease
Omim
Each of the 3 new cases presented differently: the first with nephrotic syndrome, the second with fetal and neonatal ascites, and the third with fetal ascites and esophageal atresia type III. Coarse facies, fair complexion, hepatosplenomegaly, and severe psychomotor retardation were constant findings. Nephrotic syndrome occurred in 4 of 7 cases in which renal studies were performed. ... INHERITANCE - Autosomal recessive GROWTH Other - Failure to thrive HEAD & NECK Face - Coarse facial features Eyes - Clear cornea - Albinoid fundi - Epicanthal folds - Ptosis - Nystagmus Nose - Anteverted nose Mouth - Gum hypertrophy - High-arched palate CARDIOVASCULAR Heart - Cardiomegaly - Heart failure CHEST Ribs Sternum Clavicles & Scapulae - Mild rib widening ABDOMEN - Ascites Liver - Hepatomegaly Spleen - Splenomegaly GENITOURINARY Kidneys - Nephrotic syndrome SKELETAL - Osteopenia Skull - J-shaped sella Limbs - Metaphyseal irregularities Feet - Calcaneal calcifications SKIN, NAILS, & HAIR Skin - Hypopigmented skin Hair - Fair hair NEUROLOGIC Central Nervous System - Developmental delay - Hypotonia - Seizures - Hydrocephalus - Cerebral atrophy PRENATAL MANIFESTATIONS - Hydrops fetalis Delivery - Premature birth LABORATORY ABNORMALITIES - Increased urinary free sialic acid (N-acetylneuraminic acid, 20-200x normal) - Increased fibroblast free sialic acid - Enlarged lysosomal vacuoles in lymphocytes - Conjugated hyperbilirubinemia MISCELLANEOUS - Allelic to Sialuria, Finnish type ( 604369 ) - Early death (mean age 13 months) MOLECULAR BASIS - Caused by mutations in the solute carrier family 17 (sodium phosphate), member 5 gene (SLC17A5, 604322.0002 ) ▲ Close
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Cutis Laxa, Autosomal Recessive, Type Ia
Omim
The skin lacks elastic recoil, in marked contrast to the hyperelasticity apparent in classical Ehlers-Danlos syndrome (see 130000). These properties are nearly always attributable to loss, fragmentation, or severe disorganization of dermal elastic fibers (summary by Davidson and Giro, 2002). ... Classification of autosomal recessive cutis laxa is further divided into type II (ARCL2), associated with bone dystrophy, joint laxity, and developmental delay; and type III (ARCL3), or de Barsy syndrome, which presents very severe symptoms, with ocular involvement and mental retardation (summary by Davidson and Giro, 2002). ... The father and many of his relatives had the benign hypermobile form of Ehlers-Danlos syndrome. Beighton (1972) reported a case with first-cousin parents and a case resulting from a father-daughter mating.
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Glanders
Wikipedia
WAHID Interface - OIE World Animal Health Information Database Disease card Animal health aspects of glanders Center for Biosecurity Agent Fact Sheet Burkholderia mallei genomes and related information at PATRIC , a Bioinformatics Resource Center funded by NIAID Notes On Glander Disease in Horse v t e Proteobacteria -associated Gram-negative bacterial infections α Rickettsiales Rickettsiaceae / ( Rickettsioses ) Typhus Rickettsia typhi Murine typhus Rickettsia prowazekii Epidemic typhus , Brill–Zinsser disease , Flying squirrel typhus Spotted fever Tick-borne Rickettsia rickettsii Rocky Mountain spotted fever Rickettsia conorii Boutonneuse fever Rickettsia japonica Japanese spotted fever Rickettsia sibirica North Asian tick typhus Rickettsia australis Queensland tick typhus Rickettsia honei Flinders Island spotted fever Rickettsia africae African tick bite fever Rickettsia parkeri American tick bite fever Rickettsia aeschlimannii Rickettsia aeschlimannii infection Mite-borne Rickettsia akari Rickettsialpox Orientia tsutsugamushi Scrub typhus Flea-borne Rickettsia felis Flea-borne spotted fever Anaplasmataceae Ehrlichiosis : Anaplasma phagocytophilum Human granulocytic anaplasmosis , Anaplasmosis Ehrlichia chaffeensis Human monocytotropic ehrlichiosis Ehrlichia ewingii Ehrlichiosis ewingii infection Rhizobiales Brucellaceae Brucella abortus Brucellosis Bartonellaceae Bartonellosis : Bartonella henselae Cat-scratch disease Bartonella quintana Trench fever Either B. henselae or B. quintana Bacillary angiomatosis Bartonella bacilliformis Carrion's disease , Verruga peruana β Neisseriales M+ Neisseria meningitidis/meningococcus Meningococcal disease , Waterhouse–Friderichsen syndrome , Meningococcal septicaemia M− Neisseria gonorrhoeae/gonococcus Gonorrhea ungrouped: Eikenella corrodens / Kingella kingae HACEK Chromobacterium violaceum Chromobacteriosis infection Burkholderiales Burkholderia pseudomallei Melioidosis Burkholderia mallei Glanders Burkholderia cepacia complex Bordetella pertussis / Bordetella parapertussis Pertussis γ Enterobacteriales ( OX− ) Lac+ Klebsiella pneumoniae Rhinoscleroma , Pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli : Enterotoxigenic Enteroinvasive Enterohemorrhagic O157:H7 O104:H4 Hemolytic-uremic syndrome Enterobacter aerogenes / Enterobacter cloacae Slow/weak Serratia marcescens Serratia infection Citrobacter koseri / Citrobacter freundii Lac− H2S+ Salmonella enterica Typhoid fever , Paratyphoid fever , Salmonellosis H2S− Shigella dysenteriae / sonnei / flexneri / boydii Shigellosis , Bacillary dysentery Proteus mirabilis / Proteus vulgaris Yersinia pestis Plague / Bubonic plague Yersinia enterocolitica Yersiniosis Yersinia pseudotuberculosis Far East scarlet-like fever Pasteurellales Haemophilus : H. influenzae Haemophilus meningitis Brazilian purpuric fever H. ducreyi Chancroid H. parainfluenzae HACEK Pasteurella multocida Pasteurellosis Actinobacillus Actinobacillosis Aggregatibacter actinomycetemcomitans HACEK Legionellales Legionella pneumophila / Legionella longbeachae Legionnaires' disease Coxiella burnetii Q fever Thiotrichales Francisella tularensis Tularemia Vibrionaceae Vibrio cholerae Cholera Vibrio vulnificus Vibrio parahaemolyticus Vibrio alginolyticus Plesiomonas shigelloides Pseudomonadales Pseudomonas aeruginosa Pseudomonas infection Moraxella catarrhalis Acinetobacter baumannii Xanthomonadaceae Stenotrophomonas maltophilia Cardiobacteriaceae Cardiobacterium hominis HACEK Aeromonadales Aeromonas hydrophila / Aeromonas veronii Aeromonas infection ε Campylobacterales Campylobacter jejuni Campylobacteriosis , Guillain–Barré syndrome Helicobacter pylori Peptic ulcer , MALT lymphoma , Gastric cancer Helicobacter cinaedi Helicobacter cellulitis Authority control GND : 4578160-6
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Glycogen Storage Disease
Wikipedia
Exercise-induced muscle cramps and weakness Myoglobinuria [13] GSD XI / GSD 11 Muscle lactate dehydrogenase ( LDHA ) ? ? ? ? Fanconi-Bickel syndrome formerly GSD XI / GSD 11, no longer considered a GSD Glucose transporter ( GLUT2 ) ? ... GSD type VIII (GSD 8): In the past it was considered a distinct condition, [16] however it is now classified with GSD type VI [17] or GSD IXa1; [18] it has been described as X-linked recessive inherited. [19] GSD type XI (GSD 11): Fanconi-Bickel syndrome , hepatorenal glycogenosis with renal Fanconi syndrome, no longer considered a glycogen storage disease. [3] GSD type XIV (GSD 14): Now classed as Congenital disorder of glycosylation type 1 (CDG1T), affects the phosphoglucomutase enzyme (gene PGM1). [3] Lafora disease is considered a complex neurodegenerative disease and also a glycogen metabolism disorder. [20] Diagnosis [ edit ] Micrograph of glycogen storage disease with histologic features consistent with Cori disease .PHKA2, PHKG2, GYG1, G6PC, SLC37A4, GAA, GYS2, AGL, PFKM, GBE1, PGM1, PYGM, PGAM2, LAMP2, FBP1, GYG2, PYGL, ALDOA, PHKB, NHLRC1, PGK1, PFKL, EPM2A, FBP2, ENO3, LDHA, GYS1, PHKA1, TRAPPC4, MGAM, SI, PRKAG2, SLC2A2, BTD, MFRP, POLDIP3, G6PC3, H3P36, NSUN2, G6PC2, NT5C3A, C1QTNF5, VWF, ABCA1, MNAT1, PHEX, ACADM, ANXA2, APRT, SLC25A20, SCARB1, CSF3, EHHADH, GH1, GLA, CXCL2, HADHA, HNF4A, IDUA, CXCL8, MB, MFAP1, H3C9P
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Arthritis Mutilans
Wikipedia
As the condition worsens, luxation , phalangeal and metacarpal bone absorption, and skeletal architecture loss in the fingers occurs. [5] Cause [ edit ] Arthritis mutilans occurs mainly in people who have pre-existing psoriatic arthritis , but can occur, if less often, in advanced rheumatoid arthritis; it can also occur independently. [5] [6] Psoriasis and psoriatic arthritis are interrelated heritable diseases, occurring with greater heritable frequency than rheumatoid arthritis , primary Sjögren syndrome and thyroid disease. [7] Psoriasis affects 2–3% of the Caucasian population, and psoriatic arthritis affects up to 30% of those. [7] Arthritis mutilans presents in about 5–16% of psoriatic arthritis cases, involves osteolysis of the DIP and PIP joints, and can include bone edema , bone erosions , and new bone growth. [8] Most often psoriatic arthritis is seronegative for rheumatoid factor (occurring in only about 13% of cases [9] ), and has genetic risk factor overlap with ankylosing spondylitis with HLA-B27 , IL-23R77 , and IL-1 , [7] however, as of 2016, immunopathogenesis is unclear. [8] Diagnosis [ edit ] Enthesitis can assist in differentiating arthritis mutilans' parent condition psoriatic arthritis from rheumatoid arthritis and osteoarthritis , with evidence in plain radiographs (x-rays) and MRI as periostitis , new bone formation, and bone erosions. [7] Dactylitis , spondylitis and sacroiliitis are common with the parent condition psoriatic arthritis, but are not in rheumatoid arthritis. [9] MRI bone edema scores are high in arthritis mutilans and correlate with radiographic measures of joint damage, although they may not correlate with disease activity. [10] A source of significant pain, bone marrow edema (or lesions, using newer terminology), can be detected on MRI or with ultrasonography by signals of excessive water in bone marrow. [11] Specifically, bone marrow edema can be detected within bone on T1-weighted images as poorly defined areas of low signal, with a high signal on T2-weighted fat-suppressed images. [12] Comparatively, with arthritis mutilans in rheumatoid arthritis , bone marrow edema often involves the subchondral bone layer, while the condition as a subtype of psoriatic arthritis includes a greater extent of marrow edema, expanding to diaphysis . [10] [13] Treatment [ edit ] Medication [ edit ] The bone edema in arthritis mutilans can be treated with TNF inhibitors in the short term: a 2007 study found that the bone edema associated with psoriatic arthritis (of which arthritis mutilans is a subtype) responded to TNF inhibitors with "dramatic" improvement, but the study was not determinative of whether TNF inhibitors would prevent new bone formation, bone fusion, or osteolysis ( bone resorption ). [10] [14] Surgical [ edit ] Although a 2011 research article stated that disagreements between hand surgeons and rheumatologists remain regarding the indications, timing and effectiveness of rheumatoid hand surgery, [15] arthritis mutilans may be successfully treated by iliac - bone graft and arthrodesis of the interphalangeal joints and the metacarpophalangeal joint in each finger. [5] [16] Outcomes [ edit ] Arthritis mutilans' parent condition psoriatic arthritis leaves people with a mortality risk 60% higher than the general population, with premature death causes mirroring those of the general population, cardiovascular issues being most common. [9] [17] Life expectancy for people with psoriatic arthritis is estimated to be reduced by approximately 3 years. [9] References [ edit ] ^ National Institutes of Health Genetics Home Reference, Psoriatic arthritis . ... External links [ edit ] Classification D ICD - 10 : M07.1 ICD - 9-CM : 696 DiseasesDB : C0702102 v t e Diseases of joints General Arthritis Monoarthritis Oligoarthritis Polyarthritis Symptoms Joint pain Joint stiffness Inflammatory Infectious Septic arthritis Tuberculosis arthritis Crystal Chondrocalcinosis CPPD (Psudogout) Gout Seronegative Reactive arthritis Psoriatic arthritis Ankylosing spondylitis Other Juvenile idiopathic arthritis Rheumatoid arthritis Felty's syndrome Palindromic rheumatism Adult-onset Still's disease Noninflammatory Hemarthrosis Osteoarthritis Heberden's node Bouchard's nodes Osteophyte v t e Spinal disease Deforming Spinal curvature Kyphosis Lordosis Scoliosis Other Scheuermann's disease Torticollis Spondylopathy inflammatory Spondylitis Ankylosing spondylitis Sacroiliitis Discitis Spondylodiscitis Pott disease non inflammatory Spondylosis Spondylolysis Spondylolisthesis Retrolisthesis Spinal stenosis Facet syndrome Back pain Neck pain Upper back pain Low back pain Coccydynia Sciatica Radiculopathy Intervertebral disc disorder Schmorl's nodes Degenerative disc disease Spinal disc herniation Facet joint arthrosis v t e Medicine Specialties and subspecialties Surgery Cardiac surgery Cardiothoracic surgery Colorectal surgery Eye surgery General surgery Neurosurgery Oral and maxillofacial surgery Orthopedic surgery Hand surgery Otolaryngology ENT Pediatric surgery Plastic surgery Reproductive surgery Surgical oncology Transplant surgery Trauma surgery Urology Andrology Vascular surgery Internal medicine Allergy / Immunology Angiology Cardiology Endocrinology Gastroenterology Hepatology Geriatrics Hematology Hospital medicine Infectious disease Nephrology Oncology Pulmonology Rheumatology Obstetrics and gynaecology Gynaecology Gynecologic oncology Maternal–fetal medicine Obstetrics Reproductive endocrinology and infertility Urogynecology Diagnostic Radiology Interventional radiology Nuclear medicine Pathology Anatomical Clinical pathology Clinical chemistry Cytopathology Medical microbiology Transfusion medicine Other Addiction medicine Adolescent medicine Anesthesiology Dermatology Disaster medicine Diving medicine Emergency medicine Mass gathering medicine Family medicine General practice Hospital medicine Intensive care medicine Medical genetics Narcology Neurology Clinical neurophysiology Occupational medicine Ophthalmology Oral medicine Pain management Palliative care Pediatrics Neonatology Physical medicine and rehabilitation PM&R Preventive medicine Psychiatry Addiction psychiatry Radiation oncology Reproductive medicine Sexual medicine Sleep medicine Sports medicine Transplantation medicine Tropical medicine Travel medicine Venereology Medical education Medical school Bachelor of Medicine, Bachelor of Surgery Bachelor of Medical Sciences Master of Medicine Master of Surgery Doctor of Medicine Doctor of Osteopathic Medicine MD–PhD Related topics Alternative medicine Allied health Dentistry Podiatry Pharmacy Physiotherapy Molecular oncology Nanomedicine Personalized medicine Public health Rural health Therapy Traditional medicine Veterinary medicine Physician Chief physician History of medicine Book Category Commons Wikiproject Portal Outline
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Hypernatremia
Wikipedia
There are several recorded cases of forced ingestion of concentrated salt solution in exorcism rituals leading to death. [11] Mineralcorticoid excess due to a disease state such as Conn's syndrome usually does not lead to hypernatremia unless free water intake is restricted. ... External links [ edit ] Sodium at Lab Tests Online Classification D ICD - 10 : E87.0 ICD - 9-CM : 276.0 MeSH : D006955 DiseasesDB : 6266 External resources eMedicine : emerg/263 Patient UK : Hypernatremia v t e Electrolyte imbalances Sodium High Salt poisoning Low Hypotonic Isotonic Cerebral salt-wasting syndrome Potassium High Low Chloride High Low Calcium High Low Symptoms and signs Chvostek sign Trousseau sign Milk-alkali syndrome Disorders of calcium metabolism Calcinosis ( Calciphylaxis , Calcinosis cutis ) Calcification ( Metastatic calcification , Dystrophic calcification ) Familial hypocalciuric hypercalcemia Phosphate High Low Magnesium High LowPOMC, AQP2, FGFR1, ARNT2, MAGEL2, AVPR2, DSG1, REN, AGT, HSD11B2, AVP, NR3C2, RNU1-4, AGTR1, SGK1, PLG, SLC5A2, SLC12A3, LEP, ATM, SLC33A1, PGR-AS1, PLAU, SLC12A1, FGF23, SLC9A3, SLC9A1, ADD1, SLC12A2, ZIC2, NPHS2, CCL4, KL, ATP6AP2, EGLN1, MIR429, SDC1, OPRM1, SCNN1A, GH1, AQP3, CASR, CRH, CRP, ACE, DRD1, EDN1, EDNRA, GHSR, ACSM3, HIF1A, IL17A, KLKB1, LRP2, MME, COX2, ADM, PTGS2, MTCO2P12
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Obstetrical Bleeding
Wikipedia
External links [ edit ] Classification D ICD - 10 : O20, O46 , O67, O72 ICD - 9-CM : 641 , 666 Wikipedia's health care articles can be viewed offline with the Medical Wikipedia app . v t e Pathology of pregnancy , childbirth and the puerperium Pregnancy Pregnancy with abortive outcome Abortion Ectopic pregnancy Abdominal Cervical Interstitial Ovarian Heterotopic Embryo loss Fetal resorption Molar pregnancy Miscarriage Stillbirth Oedema , proteinuria and hypertensive disorders Gestational hypertension Pre-eclampsia HELLP syndrome Eclampsia Other, predominantly related to pregnancy Digestive system Acute fatty liver of pregnancy Gestational diabetes Hepatitis E Hyperemesis gravidarum Intrahepatic cholestasis of pregnancy Integumentary system / dermatoses of pregnancy Gestational pemphigoid Impetigo herpetiformis Intrahepatic cholestasis of pregnancy Linea nigra Prurigo gestationis Pruritic folliculitis of pregnancy Pruritic urticarial papules and plaques of pregnancy (PUPPP) Striae gravidarum Nervous system Chorea gravidarum Blood Gestational thrombocytopenia Pregnancy-induced hypercoagulability Maternal care related to the fetus and amniotic cavity amniotic fluid Oligohydramnios Polyhydramnios Braxton Hicks contractions chorion / amnion Amniotic band syndrome Chorioamnionitis Chorionic hematoma Monoamniotic twins Premature rupture of membranes Obstetrical bleeding Antepartum placenta Circumvallate placenta Monochorionic twins Placenta accreta Placenta praevia Placental abruption Twin-to-twin transfusion syndrome Labor Amniotic fluid embolism Cephalopelvic disproportion Dystocia Shoulder dystocia Fetal distress Locked twins Nuchal cord Obstetrical bleeding Postpartum Pain management during childbirth placenta Placenta accreta Preterm birth Postmature birth Umbilical cord prolapse Uterine inversion Uterine rupture Vasa praevia Puerperal Breastfeeding difficulties Low milk supply Cracked nipples Breast engorgement Childbirth-related posttraumatic stress disorder Diastasis symphysis pubis Postpartum bleeding Peripartum cardiomyopathy Postpartum depression Postpartum psychosis Postpartum thyroiditis Puerperal fever Puerperal mastitis Other Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy Category
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Epidemic Dropsy
Wikipedia
When mustard oil is adulterated deliberately (as in most cases) or accidentally with argemone oil, proteinuria (specifically loss of albumin ) occurs, with a resultant edema as would occur in nephrotic syndrome . Other major symptoms are bilateral pitting edema of extremities, headache , nausea , loose bowels, erythema , glaucoma and breathlessness . ... Argemone seeds find use as a substitute because of the easy availability, low cost and their complete miscibility of their oil with mustard oil. [2] Mechanism [ edit ] Mortality is usually due to heart failure, pneumonia, respiratory distress syndrome or renal failure and is around 5%. ... External links [ edit ] Classification D ICD - 10 : T62.8 DiseasesDB : 32789 v t e Poisoning Toxicity Overdose History of poison Inorganic Metals Toxic metals Beryllium Cadmium Lead Mercury Nickel Silver Thallium Tin Dietary minerals Chromium Cobalt Copper Iron Manganese Zinc Metalloids Arsenic Nonmetals Sulfuric acid Selenium Chlorine Fluoride Organic Phosphorus Pesticides Aluminium phosphide Organophosphates Nitrogen Cyanide Nicotine Nitrogen dioxide poisoning CHO alcohol Ethanol Ethylene glycol Methanol Carbon monoxide Oxygen Toluene Pharmaceutical Drug overdoses Nervous Anticholinesterase Aspirin Barbiturates Benzodiazepines Cocaine Lithium Opioids Paracetamol Tricyclic antidepressants Cardiovascular Digoxin Dipyridamole Vitamin poisoning Vitamin A Vitamin D Vitamin E Megavitamin-B 6 syndrome Biological 1 Fish / seafood Ciguatera Haff disease Ichthyoallyeinotoxism Scombroid Shellfish poisoning Amnesic Diarrhetic Neurotoxic Paralytic Other vertebrates amphibian venom Batrachotoxin Bombesin Bufotenin Physalaemin birds / quail Coturnism snake venom Alpha-Bungarotoxin Ancrod Batroxobin Arthropods Arthropod bites and stings bee sting / bee venom Apamin Melittin scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism Loxoscelism tick paralysis Plants / fungi Cinchonism Ergotism Lathyrism Locoism Mushrooms Strychnine 1 including venoms , toxins , foodborne illnesses .
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Congenital Dyserythropoietic Anemia
Wikipedia
External links [ edit ] Classification D ICD - 10 : D64.4 ICD - 9-CM : 285.8 MeSH : D000742 External resources Orphanet : 85 Scholia has a topic profile for Congenital dyserythropoietic anemia . v t e Medicine Specialties and subspecialties Surgery Cardiac surgery Cardiothoracic surgery Colorectal surgery Eye surgery General surgery Neurosurgery Oral and maxillofacial surgery Orthopedic surgery Hand surgery Otolaryngology ENT Pediatric surgery Plastic surgery Reproductive surgery Surgical oncology Transplant surgery Trauma surgery Urology Andrology Vascular surgery Internal medicine Allergy / Immunology Angiology Cardiology Endocrinology Gastroenterology Hepatology Geriatrics Hematology Hospital medicine Infectious disease Nephrology Oncology Pulmonology Rheumatology Obstetrics and gynaecology Gynaecology Gynecologic oncology Maternal–fetal medicine Obstetrics Reproductive endocrinology and infertility Urogynecology Diagnostic Radiology Interventional radiology Nuclear medicine Pathology Anatomical Clinical pathology Clinical chemistry Cytopathology Medical microbiology Transfusion medicine Other Addiction medicine Adolescent medicine Anesthesiology Dermatology Disaster medicine Diving medicine Emergency medicine Mass gathering medicine Family medicine General practice Hospital medicine Intensive care medicine Medical genetics Narcology Neurology Clinical neurophysiology Occupational medicine Ophthalmology Oral medicine Pain management Palliative care Pediatrics Neonatology Physical medicine and rehabilitation PM&R Preventive medicine Psychiatry Addiction psychiatry Radiation oncology Reproductive medicine Sexual medicine Sleep medicine Sports medicine Transplantation medicine Tropical medicine Travel medicine Venereology Medical education Medical school Bachelor of Medicine, Bachelor of Surgery Bachelor of Medical Sciences Master of Medicine Master of Surgery Doctor of Medicine Doctor of Osteopathic Medicine MD–PhD Related topics Alternative medicine Allied health Dentistry Podiatry Pharmacy Physiotherapy Molecular oncology Nanomedicine Personalized medicine Public health Rural health Therapy Traditional medicine Veterinary medicine Physician Chief physician History of medicine Book Category Commons Wikiproject Portal Outline v t e Diseases of red blood cells ↑ Polycythemia Polycythemia vera ↓ Anemia Nutritional Micro- : Iron-deficiency anemia Plummer–Vinson syndrome Macro- : Megaloblastic anemia Pernicious anemia Hemolytic (mostly normo- ) Hereditary enzymopathy : Glucose-6-phosphate dehydrogenase deficiency glycolysis pyruvate kinase deficiency triosephosphate isomerase deficiency hexokinase deficiency hemoglobinopathy : Thalassemia alpha beta delta Sickle cell disease / trait Hereditary persistence of fetal hemoglobin membrane : Hereditary spherocytosis Minkowski–Chauffard syndrome Hereditary elliptocytosis Southeast Asian ovalocytosis Hereditary stomatocytosis Acquired AIHA Warm antibody autoimmune hemolytic anemia Cold agglutinin disease Donath–Landsteiner hemolytic anemia Paroxysmal cold hemoglobinuria Mixed autoimmune hemolytic anemia membrane paroxysmal nocturnal hemoglobinuria Microangiopathic hemolytic anemia Thrombotic microangiopathy Hemolytic–uremic syndrome Drug-induced autoimmune Drug-induced nonautoimmune Hemolytic disease of the newborn Aplastic (mostly normo- ) Hereditary : Fanconi anemia Diamond–Blackfan anemia Acquired: Pure red cell aplasia Sideroblastic anemia Myelophthisic Blood tests Mean corpuscular volume normocytic microcytic macrocytic Mean corpuscular hemoglobin concentration normochromic hypochromic Other Methemoglobinemia Sulfhemoglobinemia Reticulocytopenia
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Puerperal Disorder
Wikipedia
External links [ edit ] Classification D ICD - 10 : O85 - O92 ICD - 9-CM : 670 - 676 MeSH : D011644 v t e Pathology of pregnancy , childbirth and the puerperium Pregnancy Pregnancy with abortive outcome Abortion Ectopic pregnancy Abdominal Cervical Interstitial Ovarian Heterotopic Embryo loss Fetal resorption Molar pregnancy Miscarriage Stillbirth Oedema , proteinuria and hypertensive disorders Gestational hypertension Pre-eclampsia HELLP syndrome Eclampsia Other, predominantly related to pregnancy Digestive system Acute fatty liver of pregnancy Gestational diabetes Hepatitis E Hyperemesis gravidarum Intrahepatic cholestasis of pregnancy Integumentary system / dermatoses of pregnancy Gestational pemphigoid Impetigo herpetiformis Intrahepatic cholestasis of pregnancy Linea nigra Prurigo gestationis Pruritic folliculitis of pregnancy Pruritic urticarial papules and plaques of pregnancy (PUPPP) Striae gravidarum Nervous system Chorea gravidarum Blood Gestational thrombocytopenia Pregnancy-induced hypercoagulability Maternal care related to the fetus and amniotic cavity amniotic fluid Oligohydramnios Polyhydramnios Braxton Hicks contractions chorion / amnion Amniotic band syndrome Chorioamnionitis Chorionic hematoma Monoamniotic twins Premature rupture of membranes Obstetrical bleeding Antepartum placenta Circumvallate placenta Monochorionic twins Placenta accreta Placenta praevia Placental abruption Twin-to-twin transfusion syndrome Labor Amniotic fluid embolism Cephalopelvic disproportion Dystocia Shoulder dystocia Fetal distress Locked twins Nuchal cord Obstetrical bleeding Postpartum Pain management during childbirth placenta Placenta accreta Preterm birth Postmature birth Umbilical cord prolapse Uterine inversion Uterine rupture Vasa praevia Puerperal Breastfeeding difficulties Low milk supply Cracked nipples Breast engorgement Childbirth-related posttraumatic stress disorder Diastasis symphysis pubis Postpartum bleeding Peripartum cardiomyopathy Postpartum depression Postpartum psychosis Postpartum thyroiditis Puerperal fever Puerperal mastitis Other Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy Category
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Tick-Borne Disease
Wikipedia
Lineage 2 POWV is also known as deer tick virus (DTV) Vector: Ixodes cookei , Ix. scapularis , Ix. marxi , Ix. spinipalpus m, Dermacentor andersoni , and D. variabilis Endemic to: North America and eastern Russia Colorado tick fever Organism: Colorado tick fever virus (CTF), a coltivirus from the Reoviridae Vector: Dermacentor andersoni Region: US (West) Crimean-Congo hemorrhagic fever Organism: CCHF virus, a nairovirus , from the Bunyaviridae Vector: Hyalomma marginatum , Rhipicephalus bursa Region: Southern part of Asia, Northern Africa, Southern Europe Severe febrile illness [16] Organism: Heartland virus , a phlebovirus , from the Bunyaviridae Vector: Lone star tick ( Amblyomma americanum ) Region: Missouri and Tennessee, United States Severe febrile illness, headaches, coma in 1/3 patients [17] Organism: tentatively Alongshan virus, jingmenvirus group in the flavivirus family Vector: tick (likely Ixodes persulcatus , Ixodes ricinus ), mosquitoes Region: Inner Mongolia but potentially more widespread Protozoan [ edit ] Babesiosis Organism: Babesia microti , Theileria equi Vector: Ixodes scapularis (deer tick), I. pacificus (western black-legged tick) Region (US): Northeast, West Coast Cytauxzoonosis Organism: Cytauxzoon felis Vector: Amblyomma americanum (Lone star tick) Region (US): South, Southeast Toxin [ edit ] Tick paralysis Cause: Toxin Vector (US): Dermacentor andersoni (Rocky Mountain wood tick), D. variabilis (American dog tick or wood tick) Region (US): D. andersoni : East, D. variabilis : East, West coast Vector (Australia): Ixodes holocyclus (Australian paralysis tick) [18] Region (Australia): East Allergies [ edit ] Alpha-gal allergy - Alpha-gal syndrome caused by immune reaction to the Alpha-gal sugar molecule introduced by ticks. ... External links [ edit ] Classification D MeSH : D017282 External resources eMedicine : emerg/584 Tick-Borne Diseases: Recommendations for Workers and Employers —National Institute for Occupational Safety and Health Tickborne Diseases —National Center for Infectious Diseases (CDC) Tickborne Disease Website —Massachusetts Department of Public Health Ixodes Scapularis —3D animation of Deer or Blacklegged Tick from US Army site Parasitic Insects, Mites and Ticks: Genera of Medical and Veterinary Importance Wikibooks v t e Tick-borne diseases and infestations Diseases Bacterial infections Rickettsiales Anaplasmosis Boutonneuse fever Ehrlichiosis ( Human granulocytic , Human monocytotropic , Human E. ewingii infection ) Scrub typhus Spotted fever rickettsiosis Pacific Coast tick fever American tick bite fever rickettsialpox Rocky Mountain spotted fever ) Spirochaete Baggio–Yoshinari syndrome Lyme disease Relapsing fever borreliosis Thiotrichales Tularemia Viral infections Bhanja virus Bourbon virus Colorado tick fever Crimean–Congo hemorrhagic fever Heartland bandavirus Kemerovo tickborne viral fever Kyasanur Forest disease Omsk hemorrhagic fever Powassan encephalitis Severe fever with thrombocytopenia syndrome Tete orthobunyavirus Tick-borne encephalitis Protozoan infections Babesiosis Other diseases Tick paralysis Alpha-gal allergy Southern tick-associated rash illness Infestations Tick infestation Species and bites Amblyomma Amblyomma americanum Amblyomma cajennense Amblyomma triguttatum Dermacentor Dermacentor andersoni Dermacentor variabilis Ixodes Ixodes cornuatus Ixodes holocyclus Ixodes pacificus Ixodes ricinus Ixodes scapularis Ornithodoros Ornithodoros gurneyi Ornithodoros hermsi Ornithodoros moubata Other Rhipicephalus sanguineus
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Elevated Alkaline Phosphatase
Wikipedia
Elevated alkaline phosphate is associated with certain medical conditions [3] or syndromes (e.g., hyperphosphatasia with mental retardation syndrome , HPMRS). It serves as a significant indication for certain medical conditions, diseases and syndromes. If the reason for alkaline phosphatase is unknown, isoenzyme studies using electrophoresis can confirm the source of the ALP.
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Hyperplasia
Wikipedia
Some of the more commonly known clinical forms of hyperplasia, or conditions leading to hyperplasia, are: Benign prostatic hyperplasia , also known as prostate enlargement. [1] Cushing's disease – Physiopathology of hyperplasia of adrenal cortex due to increased circulating level of ACTH (adrenocorticotropic hormone). [18] Congenital adrenal hyperplasia – Inherited disorder of gland (adrenal). [19] Endometrial hyperplasia – Hyperproliferation of the endometrium, usually in response to unopposed estrogen stimulation in the setting of polycystic ovary syndrome or exogenous administration of hormones. ... ISBN 9781607950141 . ^ Cushing's Syndrome: New Insights for the Healthcare Professional: 2013 Edition: ScholarlyBrief . ... External links [ edit ] Classification D MeSH : D006965 SNOMED CT : 76197007 External resources MedlinePlus : 003441 Scholia has a topic profile for Hyperplasia . v t e Overview of tumors , cancer and oncology Conditions Benign tumors Hyperplasia Cyst Pseudocyst Hamartoma Malignant progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck ( oral , nasopharyngeal ) Digestive system Respiratory system Bone Skin Blood Urogenital Nervous system Endocrine system Histology Carcinoma Sarcoma Blastoma Papilloma Adenoma Other Precancerous condition Paraneoplastic syndrome Staging / grading TNM Ann Arbor Prostate cancer staging Gleason grading system Dukes classification Carcinogenesis Cancer cell Carcinogen Tumor suppressor genes / oncogenes Clonally transmissible cancer Oncovirus Carcinogenic bacteria Misc.TGFB1, CCND1, MMP9, HMOX1, IL13, LEP, OGG1, PTGS2, HIF1A, TCF7L2, ZFP36, MAPK6, GLP1R, PRG4, NFE2L2, MYCN, MAT1A, KDM1A, LDLR, KCNK1, BRD4, IL9, HSPB1, RLN3, PIK3CA, AKT1, MIR340, COL2A1, EGFR, MMP2, PAM, TGFBR2, CCNB1, MMP1, CDKN1A, ASCL1, IKBKB, CSK, CDKN2A, TP53, KRAS, PTEN, CAV1, VDR, PLAU, LHCGR, IRS1, GJA1, STAR, CASR, IRS2, PDE11A, RET, XIAP, BCL2, IL25, TGFA, KRT75, TERT, NOD2, SOD1, SHBG, SCG5, SCN9A, SAA1, S100A9, BLM, TNFRSF13B, TNF, TNFAIP3, AREG, TNFRSF10D, TNFSF10, TP63, TNFSF13B, IRS4, AR, SLC7A5, CXCR4, VGF, VEGFC, VEGFA, RXRA, KLK3, TPMT, TP73, CCN5, RXRG, EPOR, RLN2, HGF, IL15, CHGA, IL4, CCN1, IGFBP3, IGF1, HTR4, HBEGF, GPX1, RLN1, GNAS, EPO, FPR2, FN1, FOXO3, FOXO1, FGF2, EZH2, INSL3, ITGB1, CDKN2B, KRT5, PTK2, BMPR2, PTGIR, CALB2, PRKAR1A, ESR2, PLAUR, PAPPA, SERPINE1, P2RX7, OXTR, CD34, MUC5AC, APEX1, MEN1, CDH1, MARCKS, POMC
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Relapsing Fever
Wikipedia
External links [ edit ] CDC: Relapsing Fever v t e Bacterial diseases due to gram negative non- proteobacteria ( BV4 ) Spirochaete Spirochaetaceae Treponema Treponema pallidum Syphilis / bejel Yaws Treponema carateum ( Pinta ) Treponema denticola Borrelia Borrelia burgdorferi / Borrelia afzelii Lyme disease Erythema migrans Neuroborreliosis Borrelia recurrentis ( Louse borne relapsing fever ) Borrelia hermsii / Borrelia duttoni / Borrelia parkeri ( Tick borne relapsing fever ) Leptospiraceae Leptospira Leptospira interrogans ( Leptospirosis ) Chlamydiaceae Chlamydia Chlamydia psittaci ( Psittacosis ) Chlamydia pneumoniae Chlamydia trachomatis Chlamydia Lymphogranuloma venereum Trachoma Bacteroidetes Bacteroides fragilis Tannerella forsythia Capnocytophaga canimorsus Porphyromonas gingivalis Prevotella intermedia Fusobacteria Fusobacterium necrophorum ( Lemierre's syndrome ) Fusobacterium nucleatum Fusobacterium polymorphum Streptobacillus moniliformis ( Rat-bite fever / Haverhill fever ) v t e Tick-borne diseases and infestations Diseases Bacterial infections Rickettsiales Anaplasmosis Boutonneuse fever Ehrlichiosis ( Human granulocytic , Human monocytotropic , Human E. ewingii infection ) Scrub typhus Spotted fever rickettsiosis Pacific Coast tick fever American tick bite fever rickettsialpox Rocky Mountain spotted fever ) Spirochaete Baggio–Yoshinari syndrome Lyme disease Relapsing fever borreliosis Thiotrichales Tularemia Viral infections Bhanja virus Bourbon virus Colorado tick fever Crimean–Congo hemorrhagic fever Heartland bandavirus Kemerovo tickborne viral fever Kyasanur Forest disease Omsk hemorrhagic fever Powassan encephalitis Severe fever with thrombocytopenia syndrome Tete orthobunyavirus Tick-borne encephalitis Protozoan infections Babesiosis Other diseases Tick paralysis Alpha-gal allergy Southern tick-associated rash illness Infestations Tick infestation Species and bites Amblyomma Amblyomma americanum Amblyomma cajennense Amblyomma triguttatum Dermacentor Dermacentor andersoni Dermacentor variabilis Ixodes Ixodes cornuatus Ixodes holocyclus Ixodes pacificus Ixodes ricinus Ixodes scapularis Ornithodoros Ornithodoros gurneyi Ornithodoros hermsi Ornithodoros moubata Other Rhipicephalus sanguineus Authority control NDL : 00564580IL1RN, TNFRSF1A, NLRP12, MEFV, NLRP3, NTRK1, LPIN2, XIAP, BCAP31, STXBP2, ELP1, CRLF1, SLC29A3, SH3KBP1, QDPR, NOD2, ORAI1, ZFHX2, RNF168, IBA57, SLC12A3, STIM1, PTS, PMP22, GCH1, PSMB9, GALC, LIFR, MVK, PEX6, PSMB4, CYP21A2, PSMB8, CYP11B2, IL2RG, TNF, CFH, HSPD1, ELANE, CXCL8, NLRC4, CPVL, ADA2, NT5C2, POLD3, TRBV20OR9-2, CRP, VHLL
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Webbed Penis
Wikipedia
PMID 26088081 . v t e Male congenital anomalies of the genitalia, including Intersex and DSD Internal Testicle Cryptorchidism Polyorchidism Monorchism Anorchia Sertoli cell-only syndrome True hermaphroditism Mixed gonadal dysgenesis Swyer syndrome Vas deferens Congenital absence of the vas deferens Other Persistent Müllerian duct syndrome External Penis Hypospadias Epispadias Chordee Micropenis Penile agenesis Diphallia Penoscrotal transposition Other Pseudohermaphroditism
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Hypotrichosis 8
Omim
Woolly hair is also a feature of several syndromes, such as Naxos disease (601214) and cardiofaciocutaneous syndrome (115150) (Petukhova et al., 2009), or the palmoplantar keratoderma and cardiomyopathy syndrome (601214) (Carvajal-Huerta, 1998).
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Short Sleeper
Omim
See also familial advanced sleep-phase syndrome (FASPS; 604348), which is a distinct disorder characterized by very early sleep onset and offset.
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Hyperthyroxinemia, Euthyroid, Caused By Generalized 5-Prime-Deiodinase Deficiency
Omim
Thus, the girl appeared to have a previously unrecognized syndrome of generalized 5-prime-deiodinase deficiency.