• FindZebra
  • About
  • Contact
  • Help
  • Login
Advanced
  • Iodine Deficiency Wikipedia
    Generally, however, long-standing goiters caused by iodine deficiency respond with only small amounts of shrinkage after iodine supplementation, and patients are at risk for developing hyperthyroidism . [20] Epidemiology [ edit ] Deaths due to iodine deficiency per million persons in 2012 0-0 1-1 2-3 4-18 Disability-adjusted life year for iodine deficiency per 100,000 inhabitants in 2004. [28] no data <50 50-100 100-150 150-200 200-250 250-300 300-350 350-400 400-450 450-500 500-750 >750 Iodine deficiency resulting in goiter occurs in 187 million people globally as of 2010 [update] (2.7% of the population). [6] Certain areas of the world, due to natural deficiency and unavailability of iodine, are severely affected by iodine deficiency, which affects approximately two billion people worldwide.
    TG, APOE, VEGFA, TSHR, SLC5A5, BRAF, TNF, NKX2-1, TFF3, RET, SLC26A4, NRCAM, NOTCH1, MAP1B, KDR, RBPJ, HIF1A, MTOR, FABP7, DIO2, DIO1, DLL1
  • Anti-Catholicism Wikipedia
    Then, once Cromwell had returned to England, the English Commissary, General Henry Ireton adopted a deliberate policy of crop burning and starvation, which was responsible for the majority of an estimated 600,000 deaths out of a total Irish population of 1,400,000." [28] Laws that restricted the rights of Irish Catholics [ edit ] The Great Famine of Ireland was due in part to Anti-Catholic laws.
  • Diabetes In Dogs Wikipedia
    Secondary diabetes may be caused by use of steroid medications, the hormones of estrus , acromegaly , ( spaying can resolve the diabetes), pregnancy, or other medical conditions such as Cushing's disease . [18] [28] [29] [30] In such cases, it may be possible to treat the primary medical problem and revert the animal to non-diabetic status. [31] [32] [33] Returning to non-diabetic status depends on the amount of damage the pancreatic insulin-producing beta cells have sustained. [34] [35] It happens rarely, but it is possible for a pancreatitis attack to activate the endocrine portion of the organ back into being capable of producing insulin once again in dogs. [36] It is possible for acute pancreatitis to cause a temporary, or transient diabetes, most likely due to damage to the endocrine portion's beta cells. [24] Insulin resistance that can follow a pancreatitis attack may last for some time thereafter. [37] Pancreatitis can damage the endocrine pancreas to the point where the diabetes is permanent. [24] Genetic susceptibility of certain breeds [ edit ] This list of risk factors for canine diabetes is taken from the genetic breed study that was published in 2007. ... Archived from the original on March 15, 2012 . Retrieved 28 May 2010 . CS1 maint: unfit URL ( link ) ( PDF ) ^ Schermerhorn, Thomas (2008). "Strategies for monitoring diabetes mellitus in dogs" . DVM 360 . Retrieved 28 May 2010 . ^ Cook, Audrey (1 June 2010).
  • Influenza Wikipedia
    Symptoms of influenza, [21] [22] with fever and cough the most common symptoms. [20] Approximately 33% of people with influenza are asymptomatic. [23] [24] Symptoms of influenza can start quite suddenly three to four days after infection. [25] Usually the first symptoms are chills and body aches, with fever also common early in the infection, with body temperatures ranging from 38 to 39 °C (approximately 100 to 103 °F). [26] Many people are so ill that they are confined to bed for several days, with aches and pains throughout their bodies, which are worse in their backs and legs. [27] Symptoms of influenza Fever and chills Cough Nasal congestion Runny nose Sore throat Hoarseness Earache Muscle pains Fatigue Headache Irritated, watering eyes Reddened eyes, skin (especially face) , mouth, throat and nose Petechial rash [28] In children, gastrointestinal symptoms such as vomiting , diarrhea , and abdominal pain [29] [30] (may be severe in children with influenza B) [31] It can be difficult to distinguish between the common cold and influenza in the early stages of these infections. [32] Influenza symptoms are a mixture of symptoms of common cold and pneumonia , body ache, headache, and fatigue.
    DDX58, IFITM3, MX1, CXCL10, IRF7, LAMP3, CCL2, EIF2AK2, RSAD2, STAT1, ISG15, TNFSF10, IFIH1, PLSCR1, OAS2, IFIT5, ATF3, OAS1, IFI44L, TNFAIP6, APOL6, OASL, OAS3, DDX60, RTP4, HERC6, SLC22A8, IFI44, UBE2L6, ZCCHC2, SAMD9, XAF1, SERPING1, CCL8, SCO2, MX2, GBP1, PARP12, IFI6, HERC5, IFI27, IFIT3, XIST, TOR1B, IFI35, TRIM22, IFIT2, SIGLEC1, TDRD7, TREX1, IFIT1, LY6E, SFTPD, RAB39B, IL1B, IL2, IVNS1ABP, SARS2, ERVK-6, TNF, IFNG, IFNB1, IFNA13, IFNA1, PTPN11, IL10, ROBO3, PLAAT4, IL17A, SARS1, TLR4, IL6, HLA-A, PBRM1, TLR7, LINC01672, ERVK-32, TLR2, COPD, KRT31, CRP, ZMYND10, CD248, CPVL, TLR9, TLR3, VHLL, IRF3, HMOX1, CD40LG, MAPK1, LSAMP, IGHA1, IL22, ARIH1, CSF2, MAPK14, IL4, NLRP3, ACTB, PIK3CA, NR1I2, TRIM25, MED1, IL2RA, DOCK3, PPBP, ISG20, TMPRSS2, CASP1, ST14, IL33, GRN, PKD1, PEBP1, HLA-C, RNPC3, MYD88, NCR1, MAVS, DHX9, PRNP, MRC1, ACE2, GZMB, FOLH1, TRBV20OR9-2, MBL2, ICAM1, HSPA4, HCL2, RPS19, PIK3CG, IL27, POLDIP2, CCR5, CD28, GRAP2, CD80, CFTR, RNF19A, IL5, CRK, AHSA1, LOH19CR1, SRL, IL1A, CCR2, CXCL8, SARDH, PER2, AIMP2, IFNL1, ATN1, PIK3CD, IFNAR1, PIK3CB, EIF4G1, HLA-B, TLR5, PRDX2, CFH, HLA-DRB1, HMGB1, TNFRSF9, TXN, MYO1G, IL7R, ERVW-1, IL15, KRT32, NM, HCRT, EPHA3, NHS, EGFR, DHFR, ST6GAL1, CTLA4, RAB11A, CCL5, CD86, PLG, ANP32B, POTEF, CASP3, B3GAT1, CAP1, IL17D, C4BPA, PPARG, BST2, IRF9, ABCB6, ALB, CD274, PTGS2, SDS, CARD14, EPHB2, FPR2, MPO, SPINT1, CBLIF, CFAP97, GPI, SOD1, GABPA, XPO1, NFE2L2, COX2, MFAP1, FOXP3, IPO5, RELA, NS2, CMPK1, ICOS, PPIA, MMP9, SEC14L2, MPPE1, BRD4, LNPEP, LRIT1, TGFB1, NOS2, VTRNA1-1, STAT3, PAM, SEA, XCL1, GOLPH3, SERPINB6, LAMP1, LAMC2, MUC5AC, MUC1, SMS, MYDGF, NT5C2, PAGR1, RBM45, ANP32A, PRDM1, STING1, NR4A3, BCL2, AREG, EIF4A2, APRT, ESCO2, F2RL1, FGF2, MLANA, FN1, GAST, VTN, GALNS, GAPDH, RTL1, SLC9A6, CTAA1, TNFSF9, CD79A, HACD1, CDC42, IL18R1, SORBS1, TNFRSF18, MIR223, MBTPS1, NCR2, TNFSF13B, CLK1, IL32, CPT2, CD163, MIR155, MIR146A, RIPK3, ERVK-20, ABHD2, HLA-DQB1, TRAF6, DOT1L, TRAF3, MTCO2P12, ADAR, IFNA2, IFNAR2, IGF1, LINC02605, IL7, CXCR2, IL18, ILF3, ABO, ITGAE, ITGAM, SHCBP1, EBI3, TTR, TIRAP, LOC102724971, APCS, XCR1, BATF2, LOC102723407, ANXA1, UCK2, IL17F, SOCS3, MTSS2, ATG7, ZMPSTE24, RIDA, PRPF8, B3GNT3, FLVCR1, ATP2C1, RTN3, BET1, TRIM3, PPIE, DLL1, RBMS3, IL17C, CLEC10A, DISC1, TBK1, SLC35A1, IL37, NXF1, CFDP1, BAMBI, KHDRBS1, SLC27A4, IL24, TPPP, ADAMTS7, IRAK3, PADI4, CHP1, USP18, ARHGAP45, SRRM2, MORC3, ECD, P2RX2, SNRNP200, WDTC1, TRAM1, MPRIP, SIRT1, CLEC5A, BACE1, CXCR6, SLC27A5, PTPN22, CTCF, POLD3, PLK4, BACE2, CCL27, KLK5, LILRB1, MALT1, MCF2L, CPSF4, JTB, SUGT1, IL17RA, TMED2, CKAP4, SGK3, ABCA1, IL22RA1, CD207, MIR192, TICAM2, CCL4L1, PRSS57, LINC01194, MIR144, MIR15A, MIR184, MIR198, CYCSP51, MIR200C, MIR205, MIR206, MIR21, MIR29A, MIR29B1, MIR29B2, HLA-P, RAB7B, MIR30C1, NRSN1, TARS3, B4GALNT2, NMS, IL31RA, EGFLAM, ASZ1, TRIM69, MUC15, TREML4, TICAM1, DEFT1P, BCL6B, PTF1A, IFNL3, CLEC9A, BTBD8, MIR29C, MIR30C2, CTHRC1, ERVK-21, MFT2, MIR1260A, TMED7-TICAM2, PSMB8-AS1, P2RX5-TAX1BP3, ERVK-10, ERVK-9, ERVK-18, MIR744, ERVK-25, ERVK-24, MYMX, GATD3B, ERVK-19, CST12P, H3P24, EGOT, GGTLC4P, MIR31, MIR146B, MIR34A, MIR34C, DEFB103A, MIR328, ERVK-7, MIR451A, MIR485, MIR505, GGT2, ERVK-8, MIR483, GGTLC5P, H3P38, MIR449B, MUC5B, GGTLC3, IL22RA2, SLC46A1, GEMIN4, SMU1, UGT1A4, UGT1A1, UGT1A3, OTUD4, CASZ1, MARCHF1, NUDT11, PACC1, UGT1A5, ENAH, DEFB103B, LANCL2, CCL28, SPHK2, PNO1, SH3GLB2, UGT1A9, UGT1A6, CD177, BPIFA1, MBL3P, TMED5, TMED7, DYNC1LI1, LINC00328, VPS28, HSPA14, TLR8, UGT1A7, CRLF3, DDX41, ISYNA1, IL23A, DDIT4, UGT1A10, UGT1A8, CHPT1, AICDA, SCGB3A1, NLRC5, NDFIP1, NPL, ZBP1, UNC93B1, TLR10, TRIM56, PARP9, CHD6, DHDDS, GINS4, HOPX, MAK16, WNT3A, FRMD7, MCU, TRIM41, TARS2, NLRX1, GATAD2B, KLRG1, SEMA6A, ARHGAP21, SUGP1, HAMP, C6orf47, NLRC4, PRM3, HEATR6, DHX58, DMRTA1, TNMD, NOD2, CLEC7A, GORASP1, WNK1, WNK4, CALCOCO2, TARS1, DHRS2, ALYREF, GPT, CXCL1, CXCL2, GRP, PDIA3, GRSF1, GZMA, H1-2, HLA-DPB1, HMGCR, NR4A1, HNRNPK, HP, HPD, PRMT1, HES1, HSPA8, GPS1, CXCR3, GLRX, FUT2, EIF4E, EIF4G2, ENO1, ESR1, F2R, FCN2, FLT3LG, FYB1, GLDC, GAD1, GATA2, GATA3, GGT1, GH1, GLA, GLB1, HSPD1, TNC, IFNA6, EPCAM, KRT10, LAG3, LGALS9, LIF, LPO, BCAM, SH2D1A, SMAD3, KPNA4, MATN1, MAX, MBD1, MBP, MEFV, MAP3K5, MIF, KRT5, KPNA3, IFNGR1, ITGB2, IGHM, IL3, IL4R, CXCR1, IL13, INSR, IRF4, ITGB7, KPNA1, JAK3, KEL, KIR2DL1, KLK1, KLRB1, KLRC2, KLRD1, EIF4A1, S1PR1, DPEP1, CASP10, C3, C5, C5AR1, C6, CALCR, CAMK2B, CASP8, CAV1, BDNF, RUNX1T1, SERPINH1, CCK, CCND3, CCNT1, CD1A, CD2, CXCR5, BCR, CD14, ALK, ABL1, ACP3, AGA, JAG1, AHR, AKT1, ALDH2, ANXA2, BCL6, ANXA6, ANXA13, APC, BIRC3, XIAP, ARSF, BAG1, CD9, CD19, DYNC1LI2, CD55, CR2, CREB1, CREM, CSF3, CSF3R, CTNNB1, CYLD, DAP, CCR7, DDOST, DDX3X, DDX5, DEFA1, DEFB1, DLAT, DNM1, KLF6, CLCN7, CD27, CDK9, TNFRSF8, CD38, CD44, CD48, CD69, CD81, CDK1, CDKN1B, AP2M1, CDR1, CDSN, CEL, CENPF, CES1, AKR1C4, CISH, CXCL9, MIP, MPL, UGT1A, TIMP1, TNNI3, TOP1, TP53, HSP90B2P, TNFRSF4, TYR, KDM6A, TERT, UVRAG, VASP, VCP, VEGFA, VIM, BEST1, WAS, THBS1, TMBIM6, DNALI1, SNAI1, SRSF2, SRSF3, SFTPB, SGTA, ST3GAL3, SLC5A5, SLC20A1, SON, TCF7, SPR, ST13, STAT2, SYT1, TAP1, ABCA3, HNF1A, ZBTB25, CXCR4, SELL, CCL4L2, NTN1, GSTO1, AIM2, EIF2AK3, GAL3ST1, TECR, GOSR1, IKBKE, MAPKAPK2, SOCS5, NUP93, SPOCK2, TRIM14, SETDB1, BCAP31, TRIM28, TMPRSS11D, AURKB, RAB7A, PRPF18, DDX39B, PABPN1, IV, GATD3A, USP11, EPX, IFITM1, TP63, MYOM2, SOCS1, IL1RL2, SPHK1, HSPB3, CLDN2, P2RX6, PCSK7, SRSF1, SDC1, MSR1, PDR, PRDX1, SERPINE1, PAK1, PAX5, PDE7A, PDGFRB, PDPK1, PECAM1, PA2G4, PF4, ABCB1, PHB, PITX1, PKM, PKP2, PLS1, FURIN, P2RY2, POLR2A, CNOT4, COX1, MMUT, PPP1R12A, NAGA, NEU1, NFKBIB, NFKBIL1, NPY, P2RY1, NT5E, OSM, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, POLD1, POLR2B, CCL11, RPE65, PTK2, RAB5A, RAG1, RARA, RARB, DPF2, RNASE1, S100A8, PTEN, S100A11, SAA3P, SAFB, SAG, SATB1, CCL3, CCL4, PTGS1, PTBP1, POU1F1, MAP2K6, PPARA, PRD, PRKAA1, PRKAA2, PRKAB1, PRKCD, MAPK8, MAP2K7, PTAFR, PROC, PRSS8, PRTN3, PSMB8, PSMD2, PSMD4, PSMD10, H3P19
  • Asylum Seekers With Apathetic Refugee Children Wikipedia
    The book was criticized by Swedish doctor and associate professor, Tomas J Eriksson, stating that Tamas had failed to discuss why there was an increase from zero to 400 cases within a few years and why it decreased again. [28] He also stated that Tamas had failed to explain why the condition only affected children awaiting asylum and who were accompanied by family members.
  • Cervical Cancer Wikipedia
    Infection with some types of HPV is the greatest risk factor for cervical cancer, followed by smoking. [27] HIV infection is also a risk factor. [27] Not all of the causes of cervical cancer are known, however, and several other contributing factors have been implicated. [28] [29] Human papillomavirus [ edit ] HPV types 16 and 18 are the cause of 75% of cervical cancer cases globally, while 31 and 45 are the causes of another 10%. [30] Women who have sex with men who have many other sexual partners or women who have many sexual partners have a greater risk. [31] [32] Of the 150-200 types of HPV known, [33] [34] 15 are classified as high-risk types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, and 82), three as probable high-risk (26, 53, and 66), and 12 as low-risk (6, 11, 40, 42, 43, 44, 54, 61, 70, 72, 81, and CP6108). [35] Genital warts , which are a form of benign tumor of epithelial cells, are also caused by various strains of HPV.
    FGFR3, STK11, HLA-DPB1, VEGFA, CTNNB1, EGFR, MTHFR, TERT, CCND1, HOTAIR, STAT3, HLA-DPB2, NOTCH1, MYC, CASP8, TP63, ERCC1, RARB, MTOR, JAK2, POU4F1, YY1, APOBEC3B, MIR543, ZNF667-AS1, WNT5A, CLPTM1L, MIR501, WNT2, PIAS3, BIRC5, NOTCH2, HES1, CYLD, CXCR4, HLA-DQA1, CDKN1B, EXOC1, ERBB2, H3P10, PIK3CB, XRCC1, SMUG1, HLA-DRB1, BMI1, SRY, PIK3CA, MMP9, MMP2, FHIT, VEGFC, CDKN2A, ESR1, HLA-DQB1, MALAT1, CADM1, COL11A2P1, TGFB1, EZH2, CASP3, MDM2, TLR4, TNF, FOXM1, TP53, PIK3CD, C2orf83, MIR34A, MIR21, PTEN, IFNG, IL1B, CD274, IL6, BCL2, IL10, GSTM1, TLR9, RBM45, GSTT1, CTLA4, CYP1A1, PIK3CG, PTGS2, PDXP, AKT1, HIF1A, MIR126, KRT19, IL1RN, VIM, MTDH, TP73, PAX1, FAS, MEG3, RASSF1, HPGDS, HLA-A, FOXP3, CXCL8, MIR143, MIR145, HLA-B, MIR155, MAPK1, MIR214, CCNA1, SOCS1, PCNA, CXCL12, EGF, PARP1, SP1, CDKN1A, DNMT1, NEAT1, MACC1, MIR195, MAL, MTCO2P12, MIR375, IL17A, COX2, COMMD3-BMI1, GAS5, UBE3A, PVT1, MIR146A, CCK, FGF2, EPHB2, WNK1, IGF1, RELA, MIR424, MIR205, TNFSF10, ARHGAP24, ATM, SYT1, GORASP1, SIX1, CA9, EZR, GSTK1, NFE2L2, TAFA4, IGF1R, IGF2, IL1A, LGALS1, CCR2, MAPK3, IRF1, MIR497, TACSTD2, MIR182, MIR203A, MIR20A, E2F1, HMGB1, SLCO6A1, ZEB1, SPP1, COL11A2, CDKN3, SOX9, TAP2, RAD51, SIRT1, MIR200B, LGALS3, FOXO1, TP53BP1, CIP2A, LTA, KLF5, SMAD4, CALR, XRCC3, MIR144, CD28, TIMP2, KDR, F2RL1, MIR142, MIR140, CD44, CRNDE, VTCN1, MMP1, TERC, MMP7, KRAS, TUG1, MIR206, MPO, H3P23, MIR326, MIR93, HPSE, HRAS, HGF, HSPA4, MIR31, IFI27, GSTP1, MIR361, DCTN6, SPAG5, ZNRD2, TMED7, MIR29A, HDAC6, IL2, MIR27B, ZEB2, IL17D, MIR23B, MIR22, GATA3, FASLG, GABPA, SOCS3, MMP14, IL27, TICAM2, CDH1, MIR107, CDKN2B-AS1, SERPINB4, SOX2, CCL2, ABCB1, TMED7-TICAM2, NT5E, ST6GAL1, BRIP1, DAPK1, SERPINE1, SLC2A1, SKP2, CHEK1, IL17F, NFKB1, PGR, TWIST2, MTR, PSMD9, PRL, MUC1, EIF4E, IDO1, KL, PIN1, IL4, TPX2, RAC1, MIR337, ST3GAL4, TBC1D9, MIR27A, PMEL, SLC9A3R1, MIR221, PLAU, IL12B, KLF4, STIL, PKM, RBBP4, NDUFA13, RRM2, HLA-G, MIR34B, SETD2, RPE65, MUC16, UBE2C, PYCARD, TMC6, KLRK1, KHDRBS1, PPARG, POU5F1, NOP53, STOML2, YAP1, CKAP4, HMGA1, RUBCNL, MIR211, MYBL2, MIR15A, MBL2, NCL, TMC8, MIR149, MIR148A, MIR10A, CD276, MRPL36, THBS2, MET, PDCD1, MTRR, MIR139, MGMT, MIR132, STIM1, TAP1, MIR124-2, MIR125A, TCF3, MRC1, HSP90B1, UVRAG, SMAD3, SOX1, JUN, CD82, MIR130A, SLC52A1, SLC5A5, NR1I2, LAPTM4B, LGR5, SLC9A1, KRT17, DIABLO, SLC12A9, HMGA2, PEBP1, FOSL1, MIR183, SEMA6A, SLN, MIR18A, MIR17, NSD2, TLR2, SEC14L2, AR, AMHR2, G6PD, JAG1, CDC42, UCA1, CDK1, STS, GJB1, MIR433, LINC00958, CCR5, BIRC2, GLI3, BLACAT1, MIR940, EGR1, MIR378A, CAT, ERBB3, POU5F1P4, CDK4, F3, FGFR2, FGFR4, EFEMP1, FOXC1, CISH, CHI3L1, POU5F1P3, NCK1-DT, MIR494, ESR2, FN1, FOLR1, FOS, ALB, FPR1, CDK5, AMH, ELK1, DNMT3B, CALCR, ANGPT2, BDNF, DNMT3A, KLRC4-KLRK1, ACTN4, MICA, MIR506, NOL7, CD24, ROS1, SNHG14, ROCK1, RFC4, XIAP, ANXA5, RACK1, ZEB1-AS1, SLC52A3, DLX6-AS1, RECQL4, CTHRC1, NDRG1, CYP2E1, PRLR, CYP2D6, GRAP2, ANXA1, TP53INP1, PSG2, CD55, SNHG4, TACC3, HULC, SNHG12, TSLP, SERPINB3, ATXN1, S100A9, WT1-AS, CD83, COMT, APRT, OIP5-AS1, RRAS, TDRG1, DCUN1D1, FOXQ1, MIR758, MIR454, HS3ST2, CRP, HOXA11-AS, RAB5A, GOLM1, MSLN, PSMA1, MAPK14, MIR944, WWOX, CTDSPL, MDC1, MAPK8, TRIM28, IL23A, KEAP1, MIR374B, MELK, APEX1, BAG3, CASC2, ABCG2, CRKL, QKI, RB1, KIF20A, PPP2R1B, AIM2, PTPA, ROCK2, PRKAA1, CRK, MSI2, GDF15, PSG5, PRKAA2, RALA, RAF1, TNFAIP8L1, IFNL3, BCAP31, NAT2, PTTG1, NR2C2, AXL, UBE2B, PPM1D, MYDGF, TWIST1, API5, TSG101, SOX17, TRAF6, SNHG16, AKTIP, AKIP1, CCAT1, GSDMB, TNFRSF1B, TTN-AS1, STC2, USO1, CCNB1, TLR3, SEC62, TIMP3, CA12, VPS51, CXCL5, XRCC5, TFPI2, AIMP2, DEK, IL1R2, PAX8, PRDM2, MZF1, ZIC2, PCDH10, ARID1A, XRCC2, C1QBP, XIST, WNT11, WNT10B, SLC46A2, TMPOP2, BRCA1, ZNF350, SOX21-AS1, BSG, VHL, CD34, CD36, KDM3A, TIMELESS, MIR466, SOX4, RIF1, MIR2861, TSC22D1, MIR338, IER3, PIWIL2, CEBPD, CFTR, SLC6A8, BECN1, MBD2, PEG3, HCFC1R1, SHBG, MTA1, LATS1, SFRP1, HAVCR2, SYTL2, SDC1, GGH, CDK6, NRP1, AKNA, ATF1, TGFBR2, TGFBR1, CD40, CD47, TBL1XR1, CCAT2, TCF7L2, LUCAT1, TCF4, MCM10, TNFRSF11A, TNFRSF10C, FBXW7, TET1, AURKA, STC1, PPP1R2C, CDH13, CDK2, STAT1, PGD, IER5, SERPINF1, MFAP1, MIR196A1, FLNB, COPS6, MIR199B, LCN2, STMN1, MIR200A, FLT4, DKK3, FOSB, KNG1, MIR204, MIR193B, KCNH1, IL24, JUND, JUNB, FUS, MIR146B, GREM1, AGER, WIF1, MIR491, LGALS9, BTG3, MIR187, MCM2, BLCAP, MIR205HG, MIR486-1, FANCD2, PTK2B, MDK, CD46, MIR150, MIR152, MCM4, MCL1, LMX1A, MIR484, FEN1, SMAD7, SMAD2, EPCAM, MIR505, MIR503, FOXC2, MIR499A, IL37, MIR485, ITGA6, MIR224, DICER1, HSP90AA1, POU2F3, SERPIND1, HSPA5, TNFAIP8, HIC1, HK2, TRIM29, USP22, SASH1, SIRT3, MIR30A, ACTB, HOXA11, HOXA9, MIR135B, HOXA1, ACP3, SUZ12, MIR331, MIR335, HLA-DOA, HTC2, ICAM3, CXCL10, MIR425, IL18, FBXL5, MIR25, GLI1, IL12A, DGCR5, MIR26B, MIR429, SFN, GPER1, POLDIP2, IFNA1, MIR383, MIR381, CCN1, IGFBP3, RNF19A, GSK3B, ADCYAP1, MIR29B1, MIR29B2, IFNA13, ETS1, PBXIP1, SPINT2, MIR127, ALPP, AGR2, MIR106B, MIR574, NOTCH3, DHCR24, MSI1, PRKN, MIR411, TUSC8, ALDH1A1, NQO1, ANGPT1, EIF4G2, CCEPR, MIR605, NME1, MUC4, PA2G4, OGG1, NCK1, KLF1, MIR590, KMT5A, MIR10B, MIR100, ATN1, EPHA3, MMP11, TRIM3, LINC01193, LINC00511, PGRMC1, MIR137, HAGLR, MLH1, PPP1R13L, PDPN, EPO, TIMM8A, NXF1, NTRK1, HTRA2, CYCSP38, AHSA1, UHRF1, MMP13, LETMD1, PRPF31, MBD5, SZRD1, NPTN-IT1, LNCRNA-ATB, HDAC8, RXFP3, PART1, CHTOP, CCDC106, CBX8, PANDAR, NUSAP1, DCAF6, TIPARP, IRAIN, MARCHF2, DEFB103B, DNMT3L, TLR8, PNO1, KMT2E, KCNIP1, ACKR3, ADGRE2, ASAP1, AKR1B10, SH3BP1, FAM215A, GEMIN4, PCAT1, CASP14, ATXN7L3, PLAAT1, NUP107, PAK5, SALL4, TP73-AS1, SYCP3, LINC00702, LPAR3, FALEC, NUP62, DCTN4, KIF4A, BRMS1, ING4, PRMT8, ANGPTL4, EIF5A2, MLXIPL, SLC39A6, PTCSC3, H3P9, MEPE, GHET1, ERO1A, SNHG1, EFEMP2, CSAG2, LDOC1, SMYD2, ASCC1, CCAR1, MIR6857, ZBTB7A, PCBP2-OT1, DHDH, DPP8, AHDC1, ERAP1, ST7L, CASZ1, PINX1, ATAD2, MARCHF1, ATP8A2, SALL3, RRM2B, PID1, NXT1, FKBP14, C5orf66-AS1, DDN-AS1, GPC3-AS1, ESRP1, MCTS1, CHFR, KRT20, MIR6852, RBMS3, LINP1, MIR8075, SPA17, UBE2S, WNT4, MCAT, DLL4, APTX, INO80, GALNT7, RAB39A, REM1, RGCC, TRIM44, AHI1, TRPM7, LINC01535, ARHGAP17, FANCL, RIPK4, MIR6893, SFMBT1, LARP6, RHCG, CASC9, CNNM3, PTTG3P, ZNF331, YOD1, CMPK1, BRD7, OTUD5, PRSS50, NLRP2, LOC112543491, ZNF692, URGCP, NBPF1, VPS53, TRIAP1, DTL, LAMP3, GINS2, CDCA8, RTRAF, MTPAP, AGO2, CEP55, RBMX2, MYLIP, KLF13, GOLPH3L, RAB14, BBC3, SIRT7, NCKIPSD, ATAD3A, TRIM62, FOXP1, ANKRD40CL, MIR340, NNT-AS1, BCAR4, DNLZ, MAFIP, MAPK8IP2, MIR655, MIR641, MIR638, LHFPL4, CA13, MIR630, FEZF1, CSAG3, MIR625, ST20, MIR620, C17orf97, STING1, TOB1-AS1, CASC15, RASA4CP, MIR618, MIR613, MIRLET7B, MIRLET7D, MIR106A, MIR600, MIR122, MIR573, MIR449B, MIR421, MIR124-1, STXBP5-AS1, SYS1-DBNDD2, NDRG2, SNORD111B, IDO2, ADAMTS18, PRSS55, HIPK1, MTLN, MED19, LTO1, MARCHF8, SKA3, LINC00518, MIR744, CTAG1A, VTRNA2-1, MSRB3, MIR802, MYPOP, MIR9-3HG, IS1, SBF2-AS1, H19, GATC, HNF1A-AS1, ZSCAN1, LYPD5, LINC01305, PNPLA1, FAM83H, TMSB15B, TRIM59, ZAR1, SNHG20, PAX8-AS1, LGALS7B, MIR370, BDNF-AS, MIR296, MIR299, MIR379, MIR377, MIR196B, MIR301A, MIR302A, MIR30D, MIR30E, MIR373, MIR32, MIR372, MIR320A, MIR7-3, PSG10P, MIR376C, MIR96, MIR99A, MIR99B, DEFB103A, LHX8, PSG8, ZFAS1, MIR148B, MIR324, MIR367, MIR328, MIR330, MIR346, DEFB104B, MIR449A, MIR26A1, MIR362, MIR130B, LINC00273, NORAD, MIR134, MNX1-AS1, LINC02604, MIR141, LINC01128, CERNA2, MIR502, MIR181A2, MIR186, MIR192, MIR522, MIR519D, MIR197, MIR498, MIR200C, MIR432, MIR492, MIR210, MIR202, MIR212, MIR215, MIR217, MIR218-2, MIR223, MIR409, MIR20B, MIR877, DDX53, FEZF1-AS1, LRRC8E, CENPM, FTO, OCLN, BRCC3, FSD1, DSCAM-AS1, HMBOX1, NDNF, RHBDF2, RABEP2, ZNF671, GAS5-AS1, NANOG, GRHL2, ASRGL1, ALL2, LINC01133, MIR3666, RNF34, MIR3941, ITPKC, MIR374C, ZKSCAN3, COASY, ITIH5, LINC00673, YIPF5, MIR4262, SPRY4, ST6GALNAC5, RHPN1-AS1, PCAT6, USP46, CASP12, REXO1, GATAD2B, HECW2, MIB1, SPRY4-IT1, MIR4429, ARRDC3, MIR4778, MRTFA, MIR4784, MIR4636, NCOA5, NS2, JAM2, AFAP1, APOBEC3G, HPSE2, CELF6, PRDM14, PCGEM1, LHPP, SEMA4A, ROBO3, RHBDF1, ZMAT3, DLG1-AS1, ARAP3, GIHCG, MARCHF7, SHARPIN, CCDC3, MIR665, ZG16B, TPT1-AS1, TRAP, PRRT2, CYTOR, CMTM7, CALML3-AS1, NACC1, TNRC6C-AS1, TMEM54, ANIB1, LRG1, TMPO-AS1, MIR889, TMEM132D, CYB5D2, SESN2, OSCP1, CMPK2, MIR874, ZFP42, PIP5KL1, FUNDC1, DEFB104A, PIWIL4, OR2AG1, LINC00052, ILF3-DT, ZNF582, MIR216B, AMOTL1, FOXP2, WDR20, CCDC34, IL33, CALN1, JAM3, LONP2, FSD1L, MAGT1, MIR1202, MINDY4, MIR664A, MIR1266, RPAIN, MIR1297, ELOF1, MIR1246, MAK16, MIR1284, DEFB4B, SPZ1, CCDC54, AFAP1-AS1, LINC00467, FOXD2-AS1, ADO, TMEM238L, ATAD1, RITA1, AJUBA, SNHG7, CASC11, KLC4, EMC6, GEMIN2, ZNF281, IRF6, INPP5A, IL16, IL13, CXCR2, IL7R, IL6R, IL4R, IL1RAP, IL1R1, IGF2R, IFNB1, IFNA17, ID4, ID1, ICAM1, IAPP, HSPB2, IRF3, ITGA2B, LIF, ITGA4, LEP, LDHA, LAMB3, L1CAM, KRT14, KRT13, KPNB1, KLK1, KISS1, KCNK3, KCNA1, JAK3, ITPR3, STT3A, ITGAV, ITGAE, ITGA5, HSPB1, HSF1, AGFG1, HPGD, HLA-E, HLA-DQB2, MNX1, HLA-C, HGFAC, HDAC2, HCFC1, GTF2H1, GSTM3, GSTM2, GSN, PDIA3, CXCL3, NR3C1, GRB7, GPX3, GPX2, HMGB2, HMGB3, HMMR, HOXB7, HP, HOXD9, HOXD@, HOXC10, HOXC8, HOXC6, HOXB8, HOXB2, HMOX1, HOXA13, HOXA5, HNRNPA2B1, HNRNPA1, FOXA2, FOXA1, NR4A1, LGALS7, LIG1, MAPK6, PECAM1, PC, PBX3, PAX3, PAX2, REG3A, P2RX7, OCA2, YBX1, NPTX1, NPM1, NPAT, CCN3, NOS3, NOS1, NNMT, NKX6-1, NFX1, PDK1, PLA2G4A, LIPA, PLG, PRKCB, PRKCA, PRKAB1, PPP3CA, PPP1R1A, PPIA, PPBP, PPARA, POU5F1B, POU3F3, POU2F1, POLR2E, PML, PLXNB1, PLSCR1, PLOD2, PLK1, TONSL, NFKBIA, NFATC1, NEUROD1, MEST, MEN1, MAP3K5, MAP3K3, MEF2D, MECP2, MDM4, MCM7, MCM5, MBNL1, MAP2, LYN, LTBP3, CYP4F3, LOXL2, LOX, LNPEP, MELTF, SCGB2A2, KITLG, MSX2, NELL1, NDUFS6, NDUFB8, NBN, MYOD1, MYL5, MMUT, MSX1, MICB, MST1, MSH2, MYO1B, MPG, MMP15, MAP3K11, MKI67, GPC1, GOT1, GNAO1, CDK9, CDC25C, CDC25A, CDC20, CDC6, ADGRE5, CD68, CD53, ENTPD1, CD38, CD80, CCND3, CCNA2, CBR1, RUNX2, CAV1, CASP7, CA11, CDK7, CDKN2B, GNA12, CDX1, CREM, CPOX, CPE, COX8A, SLC31A1, KLF6, CCR6, CMA1, CLU, CKS2, CKB, CHRNA4, RCC1, CEACAM7, CEACAM3, CEBPA, CEACAM5, BRCA2, FOXL2, BNIP3, BMP7, APOB, BIRC3, APEH, APC, ANXA6, ANXA2, ANG, ALPI, ALK, AKT2, AIF1, NR0B1, ADM, ADAR, ADAM10, ACVR1, ABL1, AQP8, AQP1, ARF1, BAX, PRDM1, BHMT, BDKRB2, BCYRN1, BCL2L2, BCL2A1, BCHE, BAG1, RHOB, BAAT, ATR, ATP7A, ATIC, ASTN1, PHOX2A, ARHGAP1, CRH, CRIP1, CRYZ, EPAS1, FHL2, FBP1, FANCF, FANCC, FANCA, FABP5, FABP4, ESRRA, ERCC5, ERCC4, ERCC2, ERBB4, NR2F6, EPS8, EPHX1, EPHB6, EPHB4, FOXG1, FOXF2, FOXD1, XRCC6, GLI2, GLB1, GPC3, GFI1, GCNT2, KAT2A, GAPDH, FTH1P3, FOXO3, FSHR, FRZB, FRK, FRA11A, FLT3LG, FLT1, FLG, STOM, ENG, CSF1, ELF1, BRINP1, DAP, CYP19A1, CYP1B1, CYBB, CYBA, CTSS, CTSL, CTSG, CTSB, CCN2, CTAG1B, CSRP1, CSNK2A1, CSN2, CSF2, CSF1R, DCK, DCN, ACE, DUSP3, EIF4A1, EGR2, EFNA2, ECM1, TYMP, E2F3, DVL1, HBEGF, AKR1C1, DPH1, DLX1, DEFB4A, DHX9, DDX5, DDT, GADD45A, PRKCD, MAPK10, SRRM2, CD163, SOCS6, STK17A, PDLIM7, UBE2L6, MTA2, AURKB, LPAR2, SCAF11, EXO1, ATG12, AIFM1, USP8, CLDN1, SPAG9, SEMA5A, LIMD1, HSPB3, TRIP4, SLC9A3R2, FRAT1, SLIT2, ZBTB33, SCO2, SLC12A6, MFN2, RBM19, RASSF2, KMT2B, DCAF1, NUP93, KDM4A, PPIP5K1, ISG15, GOSR1, TBPL1, MAP4K4, COX5A, PLAA, RPS6KA4, P4HA2, MBD4, BCL10, RIPK1, URI1, NOL4, ABCC3, B4GALT3, SRSF9, EIF3F, NUMB, AKR1C3, EIF4EBP3, RUVBL1, PDLIM4, IFITM1, PIK3R3, ABCA4, RECK, UTF1, TNFSF14, TNFSF9, ADAM9, CFLAR, SQSTM1, SPHK1, ARHGEF7, ASAP2, AKAP4, PROM1, CCN4, NRP2, RAB11A, INPP4B, BANF1, IL18R1, TRIM24, TNFRSF10D, SNAP23, TNFRSF6B, BCL2L11, PARP2, MAP2K3, MGLL, PDAP1, ZHX1, RASSF8, KLK8, FGFR1OP, PRDM5, TENT4A, TMSB15A, METAP2, CCNI, PRSS21, PRDX3, SUB1, PAPOLA, LYVE1, MRPS30, HCP5, TUSC2, DNAJC8, ABCF2, CPEB3, CBX7, BRD4, ICMT, SF3B1, PUM2, FBXW11, RRS1, ARL6IP1, SMC5, WAPL, CEP131, KDM2A, NT5C2, KIN, SIRT2, CARD8, MLXIP, SEPTIN9, ZNF268, SRSF10, PLK2, GPNMB, CFDP1, PRMT5, BASP1, NDC80, SYCP2, TUBA1B, B3GNT3, DLEU1, PAK4, LILRB2, ABCC4, SPRY2, SPRY1, RBM5, WASF2, EBI3, CLEC10A, HOXB13, ENOX2, POSTN, NES, PLAC1, GIPC1, MASP2, POLD3, CTCF, IGF2BP1, TXNIP, SEMA4D, MRPL28, LAMTOR5, RNASEH2A, ATG7, NEBL, KAT5, SEMA3C, NR0B2, TAGLN2, SPARCL1, CCL22, CCL16, SCN8A, SCN1A, SATB1, S100B, S100A11, S100A7, S100A4, S100A1, RPS19, RPS12, RPS6KB1, RNASEL, RNASE4, RNASE3, REV3L, REN, CCL19, CXCL6, SOX14, SDHA, SMN2, SMN1, SMARCA4, HLTF, SNAI2, SLC16A1, SLC10A2, SLC6A6, SLC1A5, SIM1, ST3GAL3, SGK1, SRSF1, SFRP4, SFRP2, MAP2K4, SEL1L, REL, RECQL, RBP1, RBL1, PTK2, PTGS1, PTGER3, PTCH1, PTBP1, PSMD4, PSMD2, PSMB10, PSMB9, PSMB8, PSMB4, PSMA7, PSEN1, KLK10, MASP1, LGMN, MAP2K7, PTK6, PTK7, PTN, MOK, RBBP6, RASGRF1, RASA1, PLAAT4, RAP2B, RAP1A, RAD52, RAD51B, PTPN6, RAD21, PXN, PTX3, PTPN14, PTPN13, PTPN11, PTPN9, SMS, SNAI1, SNCB, TTR, YWHAZ, XRCC4, XPO1, XPNPEP2, WNT2B, WNT7A, WNT6, WEE1, VDR, VDAC1, VCP, NR1H2, UGCG, UCP2, UBE2E2, UBB, TYMS, ZNF84, MALL, SCLC1, NRIP1, FZD7, FZD4, CDC7, BAP1, AXIN1, TKTL1, SMC1A, NCOA3, USP7, MIA, TCL1A, KMT2D, MFAP5, PSCA, SEM1, SLC39A7, TUFT1, TRIO, SNCG, TRAF3, HNF1A, TBP, TAT, TAPBP, MAP3K7, SYK, SUV39H1, STAT6, STAT5B, STAT5A, STAT2, SSRP1, SRF, SPARC, SOX11, SOAT1, FSCN1, TCF7, TRBV20OR9-2, TDO2, KLF10, CRISP2, TOP1, TNFAIP2, TM7SF2, TKT, TIMP1, TIAM1, THOP1, TEK, THBS4, THBS1, THBD, TGFA, TFRC, TFF3, TERF2, H3P40
    • Cervical Cancer Mayo_clinic
      Overview Cervical cancer is a type of cancer that occurs in the cells of the cervix — the lower part of the uterus that connects to the vagina. Various strains of the human papillomavirus (HPV), a sexually transmitted infection, play a role in causing most cervical cancer. When exposed to HPV , the body's immune system typically prevents the virus from doing harm. In a small percentage of people, however, the virus survives for years, contributing to the process that causes some cervical cells to become cancer cells. You can reduce your risk of developing cervical cancer by having screening tests and receiving a vaccine that protects against HPV infection.
    • Cervical Cancer Omim
      A number sign (#) is used with this entry because of evidence that various genes are involved in the causation of cervical cancer. Pathogenesis In the vast majority of cases, invasive carcinoma of the uterine cervix is thought to arise from preinvasive cervical intraepithelial neoplasias, designated CIN I-CIN III, which represent a pathologic continuum from mild to severe epithelial dysplasia. Only some cases of the more dysplastic lesions progress further to invasive carcinoma. Whereas most of the precursor lesions are readily curable, the prognosis for invasive carcinoma is generally poor, making the dissection of the molecular events that cause invasion considerably important. The observations are consistent with models describing a multistep genetic pathway for human tumorigenesis as proposed by Fearon and Vogelstein (1990) for colorectal cancer.
  • Waldenström's Macroglobulinemia Wikipedia
    It is therefore believed that epigenetic modifications play a crucial role in the disease. [18] Comparative genomic hybridization identified the following chromosomal abnormalities : deletions of 6q23 and 13q14, and gains of 3q13-q28, 6p and 18q. [19] FGFR3 is overexpressed. [20] The following signalling pathways have been implicated: CD154 / CD40 [21] Akt [22] ubiquitination , p53 activation, cytochrome c release [23] NF-κB [24] [25] WNT / beta-catenin [26] mTOR [27] ERK [24] MAPK [28] Bcl-2 [29] The protein Src tyrosine kinase is overexpressed in Waldenström macroglobulinemia cells compared with control B cells. [30] Inhibition of Src arrests the cell cycle at phase G 1 and has little effect on the survival of WM or normal cells. ... "Allogeneic Stem-Cell Transplantation in Patients with Waldenstrom Macroglobulinemia: Report from the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation". Journal of Clinical Oncology . 28 (33): 4926–4934. doi : 10.1200/JCO.2009.27.3607 .
    MYD88, PAX5, IGH, LPL, CXCR4, ANPEP, MYC, ZAP70, MALT1, CDR3, MYOM2, SDC1, CXCL12, AIMP2, TCL1A, GRAP2, TCL1B, AHSA1, ACSBG1, RNF19A, IBTK, POLDIP2, IGHV4-34, BCL11A, KRT20, EXOC2, RAPH1, MAPK1, NOS1, NOTCH2, NOS2, BCL6, BCL9, BLM, BRAF, BSG, BTK, SERPING1, CCND3, CD6, MS4A1, TNFRSF8, CD40LG, CD79A, CRK, MAPK14, CTNNB1, IL4, IRF4, CD200, NCAM1, CCND1, SLC35B2
  • Giant-Cell Carcinoma Of The Lung Wikipedia
    GCCL also often metastasizes to bone, [22] adrenal, brain, [18] lung, liver, kidney, Brain metastases from GCCL are particularly likely to cause significant cerebral hemorrhages as compared to other lung cancer variants, probably due to greatly increased rates of endothelial proliferation and neovascularization, tumor tissue growth, extensive necrosis, and aggressive local infiltrative character of GCCL cells. [18] Pathogenesis [ edit ] Several studies, both in giant-cell tumor specimens and in cell lines, have identified rearrangement and amplification of the c-myc oncogene , sometimes in combination with mutations of the K-ras gene. [28] [29] Overexpression of vascular endothelial growth factor (VEGF) has been shown to occur in GCCL and is thought to be related to the high metastatic potential of this lung cancer variant. [14] Malignant giant cells identical to those found in GCCL commonly occur in lung cancer cases with a prominent major or minor clear-cell carcinoma pattern (for a discussion about this variant, see for example [30] ).
    CXCL8, MYC, CDK4, DNMT1, EGFR, HRAS, IL6, KRAS, PLAU, MAP2K7, NKX2-1, TP53, TTF1, CD274
  • Endometrial Cancer Wikipedia
    Women with this disorder have a 5–10% lifetime risk of developing endometrial cancer, [3] compared to the 2–3% risk for unaffected women. [18] Common genetic variation has also been found to affect endometrial cancer risk in large-scale genome-wide association studies . [26] [27] Sixteen genomic regions have been associated with endometrial cancer and the common variants explain up to 7% of the familial relative risk. [27] Other health problems [ edit ] Some therapies for other forms of cancer increase the lifetime risk of endometrial cancer, which is a baseline 2–3%. [18] Tamoxifen, a drug used to treat estrogen-positive breast cancers , has been associated with endometrial cancer in approximately 0.1% of users, particularly older women, but the benefits for survival from tamoxifen generally outweigh the risk of endometrial cancer. [28] A one to two-year course of tamoxifen approximately doubles the risk of endometrial cancer, and a five-year course of therapy quadruples that risk. [22] Raloxifene , a similar drug, did not raise the risk of endometrial cancer. [29] Previously having ovarian cancer is a risk factor for endometrial cancer, [30] as is having had previous radiotherapy to the pelvis. ... Pelvic recurrences are treated with surgery and radiation, and abdominal recurrences are treated with radiation and, if possible, chemotherapy. [21] Other common recurrence sites are the pelvic lymph nodes, para-aortic lymph nodes, peritoneum (28% of recurrences), and lungs, though recurrences can also occur in the brain (<1%), liver (7%), adrenal glands (1%), bones (4–7%; typically the axial skeleton ), lymph nodes outside the abdomen (0.4–1%), spleen, and muscle/soft tissue (2–6%). [53] Epidemiology [ edit ] As of 2014 [update] , approximately 320,000 women are diagnosed with endometrial cancer worldwide each year and 76,000 die, making it the sixth most common cancer in women. [3] It is more common in developed countries, where the lifetime risk of endometrial cancer in people born with uteri is 1.6%, compared to 0.6% in developing countries. [16] It occurs in 12.9 out of 100,000 women annually in developed countries. [22] In the United States, endometrial cancer is the most frequently diagnosed gynecologic cancer and, in women, the fourth most common cancer overall, [11] [19] representing 6% of all cancer cases in women. [80] In that country, as of 2014 [update] it was estimated that 52,630 women were diagnosed yearly and 8,590 would die from the disease. [25] Northern Europe, Eastern Europe, and North America have the highest rates of endometrial cancer, whereas Africa and West Asia have the lowest rates.
    PTEN, ESR1, FGFR2, PGR, VEGFA, CCND1, ESR2, CDH1, MSH6, EP300, CYP11A1, MYC, STAR, SRD5A2, AKR1C1, HOXA10, AKR1C3, TNFSF10, SPOP, HOXA11, ABCC9, SOCS3, SRSF10, DCN, EZH2, ARID1A, SEMA3B, HSD17B2, NRIP1, SEMA3F, SIX1, POLD1, PAWR, NFE2L2, SULT2B1, MTHFR, MSH3, ZEB1, MAP3K4, TP53, LASP1, CXCL8, MLH3, IGF1R, SUZ12, CCL2, CHD4, BIRC5, TSPYL2, RNF43, PLXNA3, CDKN1C, JAZF1, FBXW7, AKR1B10, RNF144B, AKR1B1, CHFR, MIR200C, CDKN2A, MET, STK11, ERRFI1, CDKN2B, CTNNB1, HNF1B, LSAMP, SH2B3, RNGTT, FAM182A, ATXN2, ECT2L, RETREG3, TMTC1, SCAF8, CLEC3A, CYP19A1, TDP2, PTGS2, MLH1, MSH2, PIK3CA, AR, MMP2, KRAS, CYP17A1, BCL2, CYP1B1, AKT1, CCN1, ERBB2, MMP9, CFLAR, COMT, STS, EMP2, FAS, SULT1A1, CD82, PPIA, SULT1E1, SERPINB2, MGMT, MDM2, LEPR, FOXO1, TNF, MMP26, WT1, IL6, EBAG9, HIF1A, IL1A, NR1I2, CTNNBIP1, RDH16, SLC12A9, CHEK2, HOXB13, FST, NDRG1, SREBF1, PROM1, PROK1, SPP1, ACKR3, SIGLEC1, SKP2, PELP1, AURKB, SHBG, ADIPOQ, SIRT1, NAPSA, SDC1, CASC2, TCF7L2, RASSF1, UGT1A1, TTF1, WNT7A, TSC2, HSP90B1, SLC22A16, HTRA3, HPSE, LRIG2, TLR4, TRIM25, FSTL1, SCGB1A1, TLR3, CXCR4, NKX2-1, C19orf33, TFF3, NCOA3, TERT, ARMC3, KIAA1324, IGF2BP3, ADM, MMP13, S100A8, CLDN4, CRP, CSNK2B, VCAN, CXADR, CYP1A1, CYP3A4, DNMT1, TYMP, EGFR, ENG, EPO, EPOR, ERCC1, ETS1, ETV5, F2RL1, FABP5, FHIT, FOS, MTOR, NR5A2, CLDN3, CPE, S100A4, MAP3K8, NR0B1, ALDH1A1, APC, BIRC2, ATM, CEACAM1, BMI1, BRCA1, BRAF, BRCA2, DDR1, CAV1, RUNX3, CCND3, CD44, CDC25B, CDH13, CDK6, CDKN1A, CDX2, CLU, NR5A1, GH1, GJB2, GSTP1, SCGB2A1, MME, MMP7, ADRB3, MMP14, MSI1, COX1, MUTYH, NEDD4, NFKB1, OVGP1, PCNA, SERPINF1, ABCB1, SERPINB5, PIK3R1, PLAU, PPARG, PRKCA, HTRA1, RARB, MDK, SMAD7, LLGL1, HSPE1, HAS1, HDAC1, HMMR, NR4A1, FOXA1, SLC29A2, HRAS, HSD3B2, HSD17B1, IGF1, L1CAM, IGFBP1, IL1B, IL1RN, INHBA, CXCL10, ITGB1, JUN, JUP, KCNN4, PERCC1
  • Concussions In Sport Wikipedia
    For a player to be allowed to return, he must be asymptomatic . [28] If a player is cleared by the Unaffiliated Neurotrauma Consultant (UNC), then they will be allowed to play but will be monitored closely throughout the game.
  • Basal-Cell Carcinoma Wikipedia
    Superficial basal-cell carcinoma (also known as "superficial multicentric basal-cell carcinoma") Occurs most commonly on the trunk and appears as an erythematous patch. [22] : 748 [23] : 647 Pigmented basal-cell carcinoma exhibits increased melanization. [22] : 748 [23] : 647 About 80% of all basal-cell carcinoma in Chinese are pigmented while this subtype is uncommon in white people . [ citation needed ] Rodent ulcer (also known as a " Jacob 's ulcer") Nodular, with central necrosis. [22] : 748 [23] : 647 Generally a large skin lesion with central necrosis. [22] : 748 [23] : 647 Fibroepithelioma of Pinkus Anastomosing epithelial strands in a fenestrated pattern [26] Most commonly occurs on the lower back. [22] : 748 [23] : 648 Polypoid basal-cell carcinoma Exophytic nodules ( polyp -like structures) Generally on head and neck. [23] : 648 Pore-like basal-cell carcinoma Resembles an enlarged pore or stellate pit. [23] : 648 Aberrant basal-cell carcinoma Absence of any apparent carcinogenic factor, and occurring in odd sites such as the scrotum , vulva , perineum , nipple, and axilla . [23] : 648 Aggressiveness patterns [ edit ] There are mainly three patterns of aggressiveness, based mainly the cohesion of cancer cells: [27] Low-level aggressive pattern Moderately aggressive pattern Highly aggressive pattern Cohesive nodular Superficial Fibroepitheliomatous pattern (anastomosing basaloid epithelial strands enclosing round islands of fibrous stroma) [28] Moderate cohesion Narrow strands and nests of basaloid cells.
    PTCH1
  • Visual Impairment Due To Intracranial Pressure Wikipedia
    Several different studies have shown a significant increase in IOP during or immediately after resistive exercise. [23] [24] [25] [26] [27] [28] [29] There is much more information available regarding aerobic exercise and ICP.
  • Mesoamerican Nephropathy Wikipedia
    NSAIDs self-prescription is particularly widespread, [18] [19] possibly due to frequent agricultural work posture-related pains, and dysuria is commonly treated with aminoglycosides , often not related to urinary tract infections but perhaps associated with dehydration itself. [18] Clinical manifestations [ edit ] Clinical manifestations, [10] [14] [20] [21] [22] and biopsy findings [21] [23] suggest MeN could be a new form of CKD, a new pathologic entity related to repeated heat stress, dehydration, salt depletion, and possibly other contributing factors, like NSAIDs abuse . [1] [3] [4] [12] [20] [21] [24] [25] [26] [27] [28] [29] [30] [31] [ excessive citations ] A recent study [32] with Wild-type mice exposed to recurrent dehydration induced by heat stress produced a similar pattern of kidney injury, thus providing a potential mechanism for MeN, by activation of the polyol pathway, via metabolism by fructokinase, resulting in generation of endogenous fructose and uric acid in the kidney that subsequently induces renal injury. [ citation needed ] Heatstress and dehydration [ edit ] The same position supported by the authors of one study developed in El Salvador, [19] but the El Salvadoran study did not find an increased odds ratio for CKD in people exposed to agrochemical products, or direct evidence linking it to pesticides.
  • Anemia Wikipedia
    Infection by intestinal nematodes feeding on blood, such as hookworms [28] and the whipworm Trichuris trichiura . [29] Iatrogenic anemia , blood loss from repeated blood draws and medical procedures [30] [31] The roots of the words anemia and ischemia both refer to the basic idea of "lack of blood", but anemia and ischemia are not the same thing in modern medical terminology. ... "National Institutes of Health Consensus Development Conference Statement on Celiac Disease, June 28-30, 2004" . Gastroenterology (Review). 128 (4 Suppl 1): S1–9. doi : 10.1053/j.gastro.2005.02.007 . ... Nobelprize.org. 1934-12-10. Archived from the original on 28 August 2010 . Retrieved 2010-08-24 . ^ a b Harvey JW (2012).
    HAMP, REN, SLC46A1, EPO, GATA1, SLC40A1, TNF, HBB, CSF3, HP, ALAS2, MTHFR, PTH, IFNA2, CSF2, TYMS, IL3, CLEC11A, PARP1, AGT, SOD2, PRL, CDK6, TF, IL2, NUP98, ASPG, ACHE, GSR, ATP7A, TNFRSF10A, HOXD13, KRAS, SLC25A37, IGF2, ATG5, ATG7, IREB2, JAK2, BMP6, ALAD, HBA1, ITPA, GPX1, HBA2, TFRC, KLF1, HBG2, CP, ACAD8, HBG1, TTR, IFNG, CALR, TP53, KIT, IL12B, TFR2, GBA, MPL, TGFB1, STAT3, F2, MUC1, PDGFRA, MPIG6B, GLRX5, MECOM, FANCB, FIP1L1, TET2, IGH, COX4I2, LCAT, THRA, SMAD4, MARS1, FANCA, HLA-B, COX10, TERT, CAD, PRKAR1A, STAT5B, RMRP, APOA1, CASR, ANK1, ACVRL1, SEC61A1, ABCA1, COQ2, TRNT1, UBE2T, PRF1, SNX10, ITGA2B, SDHA, SDHC, SDHB, ALX4, GNA14, FAM111A, NOD2, IFIH1, ITGB3, NLRC4, ITK, SCO1, OSTM1, RPS27, RPS26, RPS15A, KRT14, RPS10, LAMA3, LAMB3, LAMC2, RRM2B, COG6, RPL27, LIG4, IL7R, TERC, IL6, ALG8, HPRT1, HPGD, NDUFAF3, HMGCL, SRP54, TALDO1, SURF1, IDH1, HIF1A, NDUFAF5, GNPTAB, HELLS, KIF1B, FASTKD2, STK11, TBCE, DCLRE1C, TBXAS1, IGLV10-54, IL2RG, RPL26, VPS45, MLX, IFNGR1, FOXP1, IDH2, SLCO2A1, NABP1, ACD, TINF2, SP110, ZBTB20, LIPA, NDUFA12, KIF15, SLC11A2, PCCA, PARN, PSMB9, OCRL, SBDS, NUMA1, SAMD9, PCNT, NPM1, NPHP1, BCOR, PTH1R, NSUN2, SARS2, PCCB, PSMB8, NDUFA13, LARS1, PRKACG, PHF21A, POLG, PML, PLEC, PSAP, PHKG2, PDHA1, PHKA2, LIPT1, RTEL1, PSMB4, PFKM, PEPD, MALT1, YARS2, SH2D1A, FERMT1, TRNS1, TRNN, MTRR, FOXP3, FOXRED1, RAG1, MMP1, MMUT, CHD7, NHP2, RAG2, RARA, SMARCAL1, TACO1, ABCD4, NOP10, FANCL, NDUFV1, WRAP53, PNPO, STEAP3, NDUFV2, NDUFS8, NDUFS4, NDUFS3, NDUFA2, NDUFS2, NDUFS1, NDUFB8, NDUFA10, NDUFA9, NDUFA4, ITGB4, VPS33A, EFL1, AASS, CRP, COX15, COX8A, COX6B1, COL17A1, COL7A1, MMAA, FARSB, CLCN7, LYST, UBR1, SCO2, UNC13D, SAMD9L, PTF1A, NPHP4, IFNL3, GTF2E2, FGF23, XRCC4, SLC25A13, ELANE, NLRP3, ECHS1, TYMP, DNMT3B, MYSM1, ZBTB16, COX20, DKC1, MTFMT, RNF113A, TCIRG1, DNAJC21, DBH, MPLKIP, NDUFAF6, CTSK, SCARB2, TNFSF11, MMAB, STING1, PLEKHM1, PET100, ZBTB24, ALPL, ALB, AK2, COG1, RECQL4, CRIPT, AGXT, IFT140, KIF23, ADA, ACVR1, ACTN4, RN7SL263P, ABCB7, AIRE, BIRC3, XIAP, ERCC6L2, CA2, IRF2BP2, BTK, BRCA1, BMPR1A, NDUFS7, CCND1, STX11, SLC7A7, ATRX, ATP7B, GTF2H5, TNFRSF11A, CISD2, BCL10, RBM8A, ENG, STIM1, FANCE, LYRM7, GPT, FANCD2, ERCC2, TBL1XR1, ERCC3, IKZF1, FANCC, TMEM67, EWSR1, MAD2L2, NHEJ1, UMPS, GLA, EXT2, CTC1, COX14, WFS1, ERBB3, FANCG, NDUFAF2, SLX4, FMO3, WT1, FLI1, COA8, G6PC3, CDCA7, FERMT3, SLC19A3, G6PC, ORAI1, G6PD, USB1, PUS1, TMPRSS6, PAEP, HFE, IFNA13, IFNA1, RPS19, IL1B, EPAS1, CHMP2B, ACE, DMRT1, ERFE, TLR9, ABO, IL10, IDUA, PON1, COPD, TGM2, NFE2L2, SLC19A2, JAK1, EPOR, SF3B1, CYGB, CD59, ABCB1, IGF1, GDF15, MIR144, HEPH, PKLR, LCN2, MPO, FCGR2A, VEGFA, SLC28A2, GSTP1, CXCL8, SLC29A1, IL1A, GABPA, THAS, ICAM1, GBAP1, IL18, IL17A, SOD1, EGLN1, CEACAM5, CD274, SEC23B, SLC17A5, B2M, GSTT1, AKT1, ABL1, MIR146A, RARS1, SLC6A8, SLC11A1, TNFSF10, KL, ACR, BACH1, HMOX1, ERVK-20, IFNAR1, SOAT1, ASF1A, ERVW-1, FAS, GATA2, CCL21, TBX1, SETD2, SCD, NOS2, BCL2, CDKN2A, UGT1A1, ERVK-6, LOH19CR1, RLS1, NCOA5, INSRR, BMP4, TLR4, DNASE2, FABP1, VWF, F10, GDF11, KDR, CYP2C8, CD55, DECR1, HPSE, APOA5, MTX1, SLC28A3, CAV2, BPIFA4P, EPCAM, FLOT2, IL2RA, VDR, CA5A, CALCR, CAT, CAV1, EGFR, ERCC1, FTMT, CD34, CD40LG, MBL2, CD47, PGK1, ARL6IP5, GIPC1, IVNS1ABP, PDLIM5, RASA3, TNFSF13B, RTN3, TXNRD2, TRIM13, PPARGC1A, PCLAF, TREX1, BCL2L11, BTG3, KCNE2, NR1D2, GNLY, ADRM1, MFN2, ADAMTS13, AMMECR1, PROCR, NR1I3, NAT2, ARHGEF12, TSPAN33, OR10A4, ALKBH3, JMJD1C, SAMD14, ARID2, ASXL1, BMPER, ZFPM1, IL23R, DIRAS1, B3GLCT, CCDC26, EMB, IL17RE, CTHRC1, MUC16, ATP5IF1, INTS4, BOC, ATP11C, UOX, TMED3, SMIM10L2A, H3P10, THRA1/BTR, PCAT2, LOC102724971, LOC102723407, LINC01152, IFNL4, PCAT1, PSC, WASHC1, C20orf181, TEC, CRPPA, DNLZ, SFTPA1, WASH6P, CXADRP1, SMIM10L2B, MIR22, ESAM, DUOXA1, UBASH3B, ATOH8, PGPEP1, TRIT1, IL17RD, KRT20, BCL11A, IL23A, PRKAG2, AHSP, TLR7, AK3, IL22, IGHV3-69-1, IGHV3OR16-7, SLCO1B3, DKK3, BBC3, SAMHD1, PADI4, MMD, MOCOS, FBXW7, MEG3, IGAN1, ATAD1, BRIP1, STK40, PRSS27, ZC3H12A, DHX40, P2RY12, SLC39A8, BACH2, RBM38, IL21, ZNF471, AICDA, TTC7A, ZC4H2, CACNA2D3, LUC7L, SOX6, LPIN2, PTPN6, TCL1B, FUT1, FOLH1, FLT3, FHIT, FGF2, FECH, FCGR3B, FCGR3A, FCGR2B, FAT1, FABP3, FABP2, F11, F9, F3, ETV6, ESR1, ERBB2, EPHX1, EPHB6, DMTN, ENO1, ADGRE1, EGR1, S1PR1, E2F2, DNMT1, DNASE1, DMD, DHFR, GAST, FUT2, DDIT3, FUT3, LAIR1, KCNQ1, ISL1, ISG20, CXCL10, INHA, IL15, IL13, IL12RB1, IL12A, IL9, CXCR1, IL4, IL1RN, IFNAR2, IFNA8, HSP90AA1, HK1, HGF, CFH, H2AX, GSTM1, GPX4, GPI, GNAS, GCLC, CBLIF, GDF2, GAS6, DGCR, GADD45A, KLK4, BMP1, BCHE, AVP, ATP5F1E, ATP2B4, ARSA, ARR3, RHOC, AR, AQP3, AQP1, FASLG, KLK3, APOH, APOE, APOB, APCS, ANXA6, SLC25A5, ALOX5, ALK, ALCAM, AIF1, AHSG, AHR, AGRP, ADH1B, ADD2, ACTB, ACO1, BCL6, VPS51, DBI, CASP3, CYP1B1, CYBB, CXADR, CUX1, CTNNB1, CTLA4, CSNK1A1, CRYGD, COL11A2, ABCC2, CCR7, CCR4, CHI3L1, CHEK1, AKR1C4, CFTR, CDR1, CDKN1B, CDK4, CDH1, CDC25A, CDAN3, CD69, CD38, CD36, MS4A1, CD5L, RUNX1T1, RUNX1, LCK, LEP, LGALS3BP, TNFRSF1B, TLR3, TLR1, TIMP1, THY1, THPO, TG, TFAP2A, TEK, TRBV20OR9-2, STXBP2, STAT6, STAT5A, STAT1, ST13, TRIM21, SRY, SRC, SPTA1, SPRR2C, SPG7, SOS1, SIGLEC1, SMN2, SMN1, SLPI, SLC20A1, SLC15A1, SLC9A3, SLC4A1, TNFRSF1A, TOP1, LRPAP1, TPMT, FHL5, ADIPOQ, LHX2, EBAG9, FCGR2C, ARTN, H2BC11, TP63, THOC5, SMARCA5, CUL4A, DYRK3, CDR3, TCL1A, HMGA2, ANC, NCOA4, CUBN, HBFQTL2, WNT3, WNT2, BEST1, VHL, VAV1, UQCRFS1, UGT1A, UGCG, UBE2D1, TRV-AAC1-4, SIPA1, SHMT2, SET, SELP, PDCD1, PDC, TNFRSF11B, OAS1, NPPB, NPC1, PNP, CNOT3, NOS3, NOS1, NFE2, NFATC1, NEO1, NEK1, RPL10A, NCAM1, NBN, MTR, CYTB, MT1E, MPG, MIF, KITLG, MET, SMCP, MBP, MAOB, LTF, LTA, PDGFB, PDGFRB, ENPP1, PTPRC, SEA, CCL19, CCL5, CCL2, SCT, ACSM3, RPS15, RPS14, RPS7, RHD, RASGRF1, RAC2, RAC1, PTPN11, PFN2, PTGS2, PTEN, PRCP, PRB1, PPOX, PPARA, POU1F1, PMCH, PI4KA, PIK3CA, PIK3C2A, PGF, PGAM1, H3P22
    • Anemia Mayo_clinic
      Overview Anemia is a problem of not having enough healthy red blood cells or hemoglobin to carry oxygen to the body's tissues. Hemoglobin is a protein found in red cells that carries oxygen from the lungs to all other organs in the body. Having anemia can cause tiredness, weakness and shortness of breath. There are many forms of anemia. Each has its own cause. Anemia can be short term or long term. It can range from mild to severe. Anemia can be a warning sign of serious illness. Treatments for anemia might involve taking supplements or having medical procedures.
  • Red Scare Wikipedia
    Archived from the original on May 14, 2011 . Retrieved 2010-07-28 . ^ a b "McCarthyism [ushistory.org]" . www.ushistory.org . ... Archived from the original on May 14, 2011 . Retrieved 2010-07-28 . ^ Commission on Protecting and Reducing Government Secrecy.
  • Hiv/aids In China Wikipedia
    The bans were poorly enforced by some local governments, prompting central authorities in August 1985 to issue another notice nationwide, reiterating the ban and ordering all sub-national governments to comply. [25] On 30 January 1986, all blood products, with the sole exception of human serum albumin , were banned from import into China for both organizational and personal use. [26] Southern intravenous drug users [ edit ] Main article: HIV/AIDS in Yunnan In 1989, central authorities became aware of a large outbreak of HIV/AIDS in western Yunnan province, in the border city of Ruili . 146 cases had been identified, mostly in injection drug users (IDUs), and Yunnan soon became the most heavily impacted province in China. [1] [27] The outbreak was the first instance of a widespread, native infection in China, and stunned officials previously concerned mainly with preventing infection through sexual contact with foreigners. [20] Yunnan borders the Golden Triangle region of Southeast Asia and has been a major hub for drug trafficking. [28] [29] HIV likely crossed into China along heroin trafficking routes from Myanmar . [30] As heroin grew in popularity in Chinese border regions, injections with used needles became more common, greatly accelerating the rate of infection. [31] The disease spread over the next several years, confined mainly to drug using populations of ethnic minorities [32] in poorer, rural areas, reaching other high-risk groups and provinces by 1995. [1] [33] Sichuan and Xinjiang first reported HIV outbreaks among injection drug users in 1995, the first two provinces besides Yunnan to do so.
  • Foot-And-Mouth Disease Wikipedia
    Over 60,000,00 injections were administered to livestock by the end of 1950. [27] [28] It was a sign that U.S.–Mexico relations were improving in the post-World War II era. [29] [30] United Kingdom 1967 [ edit ] Main article: 1967 United Kingdom foot-and-mouth epidemic In October 1967, a farmer in Shropshire reported a lame sow, which was later diagnosed with FMD.
    FLNA, FSHMD1A, SAT1, SAT2, IFNG, ITGAV, JMJD6, IL15, ATG12, DCTN3, ATG5, G3BP2, BECN1, VTN, VIM, G3BP1, SEC62, EIF2AK3, AKT1, CARD8, SEA, IL23A, DDX56, IL21, NOD2, DHX58, NLRP3, STING1, MIR203A, MIR1307, ST3GAL4, RPL13, CCL20, ANXA13, APCS, ATF4, DDX1, DHODH, EEF1G, EGR1, EIF2S1, EIF4G1, ERN1, FANCG, HLA-B, IL2, ITGA5, ITGB6, ITIH4, RPSA, SH2D1A, NME1, PDR, PPIA, EIF2AK2, ERVW-4
  • Postpartum Infections Wikipedia
    Watson recommended handwashing with chlorine solution and changes of clothing for obstetric attendants "to prevent the practitioner becoming a vehicle of contagion and death between one patient and another." [27] [28] Hygienic measures [ edit ] Ignaz Semmelweis, discoverer of some of the causes of puerperal fever In 1843, Oliver Wendell Holmes Sr. published The Contagiousness of Puerperal Fever and controversially concluded that puerperal fever was frequently carried from patient to patient by physicians and nurses; he suggested that clean clothing and avoidance of autopsies by those aiding birth would prevent the spread of puerperal fever. [29] [30] Holmes quoted Dr.
  • Neurofibromatosis Type I Wikipedia
    Epileptic seizures have been reported in up to 7% of NF-1 patients. [28] Diagnosis . Electroencephalograph, magnetic resonance imaging, computed tomographic scan, single-photon emission CT and positron emission tomographic scan.
    NF1, SPRED1, NF2, RASA1, CDKN2A, TP53, PTPN11, KIT, BRAF, RET, RGS6, PDGFRA, SDHD, MRC1, EGFR, VHL, PIK3CA, MAP2K7, SDHB, HRAS, MTOR, SUZ12, PTEN, SMUG1, GH1, MLH1, PIK3CG, PIK3CD, PIK3CB, ERBB2, PAK1, NRAS, EVI2A, APRT, MFAP1, KRAS, MSH6, EPHB2, OMG, DPYSL2, MSH2, GFAP, NGFR, MAPK1, BLVRB, THRA, ALK, S100B, IDH1, CXCL12, ATRX, HOXB2, CCND1, MDK, HGF, HOXB@, HOXB1, HOXB3, VCP, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, NGF, S100A1, RUNX1, TNFRSF11B, PMS2, EGF, BTF3P11, SPP1, CD38, NME1, CCL5, SDHC, TGFB1, SST, STAT3, PGR, LRRC37B, SOX9, CDKN2B-AS1, IDH2, UTP6, TPT1, MEN1, PACC1, KITLG, CD274, SGSM3, RNMT, MPZ, HTC2, TNF, EED, CXCR4, NFIC, NFIX, SMARCB1, H3P10, BMP2, CDC42, APOBEC1, EVI2B, BRCA1, ATM, FGFR1, BCL2, EPAS1, CRYBA1, HSF1, CTNNB1, BRCA2, PROM1, HSD17B6, IQGAP1, CCN5, AR, WASF1, PICALM, LRRC37A, SNAP91, OLIG2, SPRY1, MRVI1, CITED2, CIB1, CELF1, ALDH1L1, IKBKG, TNC, KMT2D, TOP2A, TFPI, TG, CAMP, CALM3, THY1, TIA1, TIAL1, CALM2, TNXB, TOP1, CALM1, FGF23, TSC2, TTN, TYK2, USF1, VARS1, VDR, VEGFB, BMPR1A, ZMYM2, IMMT, METAP2, TLK2, SDS, LRRC37A3, RNF135, FHDC1, DNER, AMPD1, ESCO1, NMS, RSS, AKT1, THSD7A, HSR, MEX3D, ATAD5, MIR10B, MIR125A, MIR204, NF1P2, LRRC37A2, KIR2DL5B, MIR641, ADM, DUX4, NF1P1, DHDDS, TBL1XR1, TCP1, LRRC37A4P, RASSF1, ZHX2, CIC, SHROOM2, APP, PRPF31, CNNM4, HIPK2, APOB, BCL11A, CRTAC1, KMT2C, BIRC5, FBXW7, ADAP2, ANPEP, CHPT1, KIR2DL5A, RPTOR, KIAA1549, RNF213, LSM2, TERT, CD14, CNTN2, CCN3, G6PD, FOLH1, MYH2, FN1, FMR1, NFIA, NFIB, FOXG1, FH, FAP, ETV5, TBX1, NTRK3, ESR1, EREG, SERPINE1, ERBB4, PAX6, PAX7, EPHB1, PGD, PGF, GC, MMP13, GDNF, MGMT, GSTP1, IGF1R, CCN1, CXCL10, JAK2, GRN, GNRH1, LBR, LIF, MXD1, SMAD1, SMAD4, MAF, MAGEB2, MATN2, MCAM, GNA12, MDM2, GLI1, GHSR, GHR, ENO2, ADCY8, ELK3, RPS6KB1, CREB1, SCN5A, CRABP2, CGA, CFTR, CEL, CEBPD, SH3BP2, SKI, SLC6A2, SLC6A4, SMARCA2, CDKN1B, SMS, SORD, SOS1, CDK4, SOX10, SRY, CD19, AURKA, RYR1, RPS6KA1, EIF4EBP1, RHEB, PKD1, PLG, SERPINF2, PMP22, DUSP6, PNMT, POMC, PTPA, PRKAR1A, DUSP1, MAPK3, MAPK8, SARDH, PTCH1, DIAPH2, PTN, DACH1, PTPRC, RAF1, RASA2, CSF3, ASIC2
    • Neurofibromatosis, Familial Spinal Omim
      A number sign (#) is used with this entry because familial spinal neurofibromatosis is caused by heterozygous mutation in the neurofibromin gene (NF1; 613113) on chromosome 17q11. Description Spinal neurofibromatosis is an autosomal dominant disorder characterized by a high load of spinal tumors. These tumors may be asymptomatic or result in neurologic symptoms, including back pain, difficulty walking, and paresthesias. Spinal NF is considered to be a subtype of neurofibromatosis type I (NF1; 162200), which is an allelic disorder. Patients with spinal NF may or may not have the classic cutaneous cafe-au-lait pigmentary macules or ocular Lisch nodules typically observed in patients with classic NF1.
    • Neurofibromatosis, Type I Omim
      A number sign (#) is used with this entry because neurofibromatosis type I (NF1) is caused by heterozygous mutation in the neurofibromin gene (NF1; 613113) on chromosome 17q11. Description Neurofibromatosis type I is an autosomal dominant disorder characterized by cafe-au-lait spots, Lisch nodules in the eye, and fibromatous tumors of the skin. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. NF1 is sometimes referred to as 'peripheral neurofibromatosis.' The worldwide incidence of NF1 is 1 in 2,500 to 1 in 3,000 individuals (reviews by Shen et al., 1996 and Williams et al., 2009). Type II neurofibromatosis (NF2; 101000) is a genetically distinct disorder caused by mutation in the gene encoding merlin (NF2; 607379) on chromosome 22q12.
    • Neurofibromatosis 1 Gene_reviews
      Summary Clinical characteristics. Neurofibromatosis 1 (NF1) is characterized by multiple café au lait spots, axillary and inguinal freckling, multiple cutaneous neurofibromas, iris Lisch nodules, and choroidal freckling. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically. Learning disabilities are present in at least 50% of individuals with NF1. Less common but potentially more serious manifestations include optic nerve and other central nervous system gliomas, malignant peripheral nerve sheath tumors, scoliosis, tibial dysplasia, and vasculopathy. Diagnosis/testing. The diagnosis of NF1 is usually based on clinical findings.
    • Neurofibromatosis Type 1 Medlineplus
      Neurofibromatosis type 1 is a condition characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body. The signs and symptoms of this condition vary widely among affected people. Beginning in early childhood, almost all people with neurofibromatosis type 1 have multiple café-au-lait spots , which are flat patches on the skin that are darker than the surrounding area. These spots increase in size and number as the individual grows older. Freckles in the underarms and groin typically develop later in childhood.
    • Neurofibromatosis Type 1 Gard
      Neurofibromatosis type 1 (NF1) is a genetic condition that affects the skin, the skeleton and the part of the nervous system outside the brain and spinal cord peripheral nervous system). The main signs and symptoms of NF1 include dark colored spots on the skin (café-au-lait spots), benign growths along the nerves (neurofibromas), and freckles in the underarm and groin. Other symptoms may include colored spots in the eye (Lisch nodules), curvature of the spine, learning disabilities, and an increased risk for cancer. The number of neurofibromas typically increases over time, and some can get large or turn cancerous and need to be removed. The severity and symptoms can vary greatly from person to person. This condition is caused by genetic changes ( DNA variants ) in the NF1 gene and is inherited in an autosomal dominant pattern.
    • Neurofibromatosis Type 1 Orphanet
      Neurofibromatosis type 1 (NF1) is a clinically heterogeneous, neurocutaneous genetic disorder characterized by café-au-lait spots, iris Lisch nodules, axillary and inguinal freckling, and multiple neurofibromas. Epidemiology Prevalence is reported to be 1/3,000 live births. NF1 is reported in many ethnic groups and affects males and females equally. Clinical description The clinical features are highly variable, even within the same family. Multiple café-au-lait macules are found in almost all patients (some at birth and most before the first year). Intertriginous freckling develops starting at 5 years of age. Multiple cutaneous and subcutaneous neurofibromas develop in adults.
  • Leprosy Wikipedia
    Archived from the original on 2013-12-12. ^ a b c "New Leprosy Bacterium: Scientists Use Genetic Fingerprint To Nail 'Killing Organism ' " . ScienceDaily . 2008-11-28. Archived from the original on 2010-03-13 . ... Wkly. Epidemiol. Rec . 87 (34): 317–28. August 2012. PMID 22919737 . ^ a b c d e f Rodrigues LC; Lockwood DNj (June 2011). ... Archived from the original on 4 December 2014 . Retrieved 28 November 2014 . ^ McMenamin, Dorothy (2011). ... Archived from the original on 13 March 2015 . Retrieved 28 February 2015 . ^ Lockwood, Diana N J; Kumar, Bhushan (2004-06-19). ... Archived from the original on 13 March 2015 . Retrieved 28 February 2015 . ^ a b Cambri, Geison; Mira, Marcelo Távora (2018-07-20).
    CCDC88B, SLC11A1, TLR2, TLR1, IL23R, RAB32, BATF3, LTA, HLA-DRB1, LACC1, CCDC122, TNFSF15, C1orf141, HLA-B, PRKN, TNF, RIPK2, SIGLEC5, IL18R1, IL10, IL1RL1, LINC02571, DELEC1, FILIP1, BBS9, COX4I1, CDH18, SLC2A13, RMI2, SNX20, LINC01091, WASF5P, UBE2V1P15, LINC00690, IFNG, NOD2, VDR, LRRK2, SDHD, PACRG, IL6, MBL2, RBM45, TLR4, MICA, ERBB2, IL4, IL12B, BTNL2, HLA-A, HSPD1, HLA-DQA1, IL2, GEM, S100A6, DDX39A, SLC26A3, MRC1, NGF, CFP, CCL4, CFH, DDX39B, TOLLIP, TGFBR2, KIR3DL1, CTLA4, IL17F, SLC7A9, IL2RA, HSD11B2, APOE, IL1B, IL10RB, CXCL10, IL17A, IL12RB2, BCHE, CD209, ACTG2, IL22, CCR2, TOR1B, FOXP3, NT5C3A, POTEM, CD274, IL37, CYP2E1, PARL, CYP19A1, ACAD8, RNU1-1, NUPR1, H3C9P, SPAG8, PTPN22, NLRP1, ACOT7, ACTG1, POTEKP, EMC3, CR1, ADGB, PWAR1, CASP8, APOA1, STING1, CD14, TNFSF8, CD40, IRGM, TIRAP, CD40LG, DEFB1, ACTBL2, IL26, GAL3ST4, SLC52A2, PINK1, CCR5, ANXA2, ZNF410, HAMP, MAVS, AKR1B10, ANXA1, FMNL1, HLA-DQB1, SOCS1, MASP2, MFN2, PCK1, HIF1A, PAEP, NOS2, NFKBIL1, MPZ, MNAT1, MICB, CIITA, LTB, LGALS3, LDLR, KIR3DL2, KIR2DS1, KDR, ISG20, IL15, IL13RA1, IL13, IL10RA, HLA-C, CXCR2, IL5RA, IL1RN, IL1A, IGF1, HSPE1, POLG, PREP, RNU1-4, FLNA, BMS1, FHL5, IL32, MAP3K14, BCL10, NR1I2, F2R, FCN1, FCN2, HLA-DRB4, FCN3, VEGFA, TOP2A, S100A1, CXCR3, GSTM1, TGFBR1, TGFB1, TFAM, TAP1, STAT3, SOD2, SLAMF1, ACACA, CCL3, S100B, SERPINA3
    • Leprosy, Susceptibility To, 1 Omim
      LPRS1 is a locus for susceptibility to paucibacillary leprosy on chromosome 10p13. In addition to information on LPRS1 (see MAPPING), this entry includes a discussion of susceptibility to leprosy in general and information on genetic heterogeneity (see HETEROGENEITY). Description Leprosy is a disease of peripheral sensory nerves that results from infection with Mycobacterium leprae, which was first detected in Bergen, Norway, in 1873 by Dr. Armauer Hansen. It can be effectively treated with long-term multidrug therapy. In 2006, more than 250,000 new cases of leprosy were reported to the World Health Organization.
    • Leprosy, Susceptibility To, 5 Omim
      A number sign (#) is used with this entry because this form of susceptibility to leprosy (LPRS5) is associated with a polymorphism in the TLR1 gene (601194). A polymorphism in the TLR1 gene is also associated with protection against leprosy. See 609888 for a discussion of leprosy susceptibility in general and information on genetic heterogeneity. Mapping LPRS5 is associated with a polymorphism in the TLR1 gene, which Taguchi et al. (1996) mapped to chromosome 4p14. Molecular Genetics Schuring et al. (2009) studied association of an asn248-to-ser (N248S; 601194.0002) SNP in the TLR1 gene and leprosy in a Bangladeshi population consisting of 842 patients and 543 controls.
    • Leprosy, Susceptibility To, 2 Omim
      See 609888 for a discussion of leprosy susceptibility in general and information on genetic heterogeneity. Mapping In a study in a Vietnamese population, Mira et al. (2003) found significant evidence for a susceptibility gene for leprosy on chromosome region 6q25; maximum likelihood binomial (MLB) lod score was 4.31. They confirmed this by family-based association analysis in an independent panel of 208 Vietnamese leprosy simplex families (i.e., families with 2 unaffected parents and 1 affected child). Mira et al. (2003) confirmed the linkage of paucibacillary leprosy to 10p13 (LPRS1; 609888), as reported by Siddiqui et al. (2001). Their evidence suggested that the 6q25 locus is involved in leprosy of both the paucibacillary and multibacillary types.
    • Leprosy, Susceptibility To, 3 Omim
      A number sign (#) is used with this entry because this form of susceptibility to leprosy (LPRS3) is associated with a polymorphism in the TLR2 gene (603028) on chromosome 4q32. See 609888 for a discussion of leprosy susceptibility in general and information on genetic heterogeneity. Mapping LPRS3 is associated with a polymorphism in the TLR2 gene, which Rock et al. (1998) mapped to chromosome 4q32. Molecular Genetics Kang and Chae (2001) identified an arg677-to-trp polymorphism (R677W; 603028.0001) in the intracellular domain of TLR2 in 10 (22%) of 45 Korean lepromatous leprosy patients, but not in any of 41 Korean tuberculoid patients or 45 Korean controls. They concluded that the R677W polymorphism in TLR2 has a role in susceptibility to lepromatous leprosy.
    • Leprosy, Susceptibility To, 6 Omim
      See 609888 for a discussion of leprosy susceptibility in general and information on genetic heterogeneity. Mapping Zhang et al. (2009) performed a genomewide association study to identify leprosy susceptibility loci in 706 patients and 1,225 controls, all of whom were self-identified Han Chinese from eastern China. Diagnosis was made on the basis of the consensus of at least 2 dermatologists. Patients and controls reported an absence of M. tuberculosis and other chronic infections. Controls lacked a history of leprosy in themselves and their families, as well as autoimmune and systemic disorders.
    • Leprosy Orphanet
      A chronic infectious disease affecting primarily the skin and peripheral nervous system. Epidemiology Worldwide annual incidence is estimated at 250,000 cases, with a large majority in India and Brazil. Clinical description A wide clinical spectrum has been described from a polar tuberculoid (localized) form (TT) to a polar lepromatous (disseminated) one (LL). Borderline forms exist: borderline tuberculoid, borderline borderline and borderline lepromatous (BT, BB, BL). Tuberculoid leprosy (TLep) or paucibacillary form includes TT and BT and lepromatous leprosy (LLep) or multibacillary form includes LL, BL and BB.
    • Leprosy, Susceptibility To, 4 Omim
      A number sign (#) is used with this entry because susceptibility to early-onset leprosy is associated with a polymorphism in the LTA gene (153440) on chromosome 6p21.3. This polymorphism accounts, in part, for susceptibility to leprosy linked to chromosome 6p21.3 (LPRS4). However, additional genetic risk factors likely underlie susceptibility to leprosy linked to chromosome 6p21.3. See 609888 for a discussion of leprosy susceptibility in general and information on genetic heterogeneity. Mapping Mira et al. (2003) detected a linkage peak associated with leprosy in the 6p21 chromosomal region, which fine mapping placed close to D6S2427 (lod = 2.7).
    • Hansen's Disease Gard
      Hansen's disease (also known as leprosy) is a rare bacterial infection that affects the skin, nerves and mucous membranes . After exposure, it may take anywhere from 2 to 10 years to develop features of the condition. Once present, common signs and symptoms include skin lesions ; muscle weakness or paralysis; eye problems that may lead to blindness; nosebleeds; severe pain; and/or numbness in the hands, feet, arms and legs. Hansen's disease is caused by the bacterium Mycobacterium leprae; however, the way in which the bacterium is transmitted (spread) is poorly understood. It appears that only about 5% of people are susceptible to the condition.
  • ←
  • 1
  • 2
    • ...
  • 181
  • 182
  • 183
  • 184
  • 185
  • 186
  • 187
  • 188
  • 189
  • →

FindZebra

contact@findzebra.com