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Disinhibition
Wikipedia
In association with the typical cognitive deficits, these sequelae characterise the frequently noted "personality changes" in TBI (Traumatic Brain Injury) patients. Disinhibition syndromes, in brain injuries and insults including brain tumors, strokes and epilepsy range from mildly inappropriate social behaviour, lack of control over one's behaviour to the full-blown mania, depending on the lesions to specific brain regions. Several studies in brain traumas and insults have demonstrated significant associations between disinhibition syndromes and dysfunction of orbitofrontal and basotemporal cortices, affecting visuospatial functions, somatosensation, and spatial memory, motoric, instinctive, affective, and intellectual behaviours. [2] Disinhibition syndromes have also been reported with mania-like manifestations in old age with lesions to the orbito-frontal and basotemporal cortex involving limbic and frontal connections (orbitofrontal circuit), especially in the right hemisphere. [3] Behavioural disinhibition as a result of damage to frontal lobe could be seen as a result of consumption of alcohol and central nervous system depressants drugs, e.g., benzodiazepines that disinhibit the frontal cortex from self-regulation and control. [4] [5] It has also been argued that ADHD, hyperactive/impulsive subtype have a general behavioural disinhibition beyond impulsivity and many morbidities or complications of ADHD, e.g., conduct disorder, anti-social personality disorder, substance abuse, and risk taking behaviours are all consequences of untreated behavioural disinhibition. [6] Treatment approaches [ edit ] This section does not cite any sources . ... PMID 9048703 . ^ Shulman KI (1997). "Disinhibition syndromes, secondary mania and bipolar disorder in old age".TARDBP, CHMP2B, TREM2, TYROBP, VCP, PSEN2, PSEN1, SQSTM1, ABCA7, TOMM40, VPS13A, MAPT, SPAST, TBK1, SORL1, TMEM106B, CHCHD10, FUS, FTL, FMR1, APP, GRN, HGSNAT, C9orf72, SST, LRRK2, PVALB, TGFB1, VIP, CD200R1, HTR3B, EBPL, ALB, REN, SLC6A4, ROBO2, AR, BDNF, CCN2, ELK3, ETFA, GALNS, NR3C1, GRM2, HCRT, HTR2A, LRP1, MUC1, OPRM1, OXA1L, PDYN, PRKCG, PRL, ALDH2, ROBO1, STIN2-VNTR
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Osteopetrosis, Autosomal Recessive 3
Omim
Ohlsson et al. (1980) observed the syndrome, which they referred to as marble brain disease, in children of 3 Saudi families. ... Bourke et al. (1981) observed this syndrome in 2 Kuwaiti Bedouin sibs. One sib showed basal ganglion calcification and mental subnormality. ... Roth et al. (1992) analyzed the molecular basis of carbonic anhydrase II deficiency in the American family in which the association of CA2 deficiency with a clinical syndrome was first recognized by Sly et al. (1972). ... Hu et al. (1992) pointed out that of the 39 reported cases of carbonic anhydrase deficiency syndrome, 72% were patients from North Africa and the Middle East countries, most, if not all, of whom were of Arabic descent.
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D-Bifunctional Protein Deficiency
Wikipedia
D-BP deficiency is the most severe peroxisomal disorder, [1] often resembling Zellweger syndrome . [2] Characteristics of the disorder include neonatal hypotonia and seizures, occurring mostly within the first month of life, as well as visual and hearing impairment. [3] Other symptoms include severe craniofacial disfiguration, psychomotor delay, and neuronal migration defects. ... Reduced pristinic acid β-oxidation is a common indicator of D-BP deficiency. [1] D-BP can be distinguished from Zellweger Syndrome by normal plasmalogen synthesis. ... "Developmental and pathological expression of peroxisomal enzymes: their relationship of D-bifunctional protein deficiency and Zellweger syndrome". Brain Res . 858 (1): 40–7. doi : 10.1016/S0006-8993(99)02423-3 . ... External links [ edit ] Classification D ICD - 10 : E80.3 OMIM : 261515 MeSH : C536663 DiseasesDB : 33358 v t e Genetic disorder , organelle: Peroxisomal disorders and lysosomal structural disorders Peroxisome biogenesis disorder Zellweger syndrome Neonatal adrenoleukodystrophy Infantile Refsum disease Adult Refsum disease-2 RCP 1 Enzyme-related Acatalasia RCP 2&3 Mevalonate kinase deficiency D-bifunctional protein deficiency Adult Refsum disease-1 Transporter-related X-linked adrenoleukodystrophy Lysosomal Danon disease See also: proteins , intermediates
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Hyperhidrosis
Wikipedia
Idiopathic unilateral circumscribed hyperhidrosis Reported association with: Blue rubber bleb nevus Glomus tumor POEMS syndrome Burning feet syndrome (Gopalan's) Trench foot Causalgia Pachydermoperiostosis Pretibial myxedema Gustatory sweating associated with: Encephalitis Syringomyelia Diabetic neuropathies Herpes zoster ( shingles ) Parotitis Parotid abscesses Thoracic sympathectomy Auriculotemporal or Frey's syndrome Miscellaneous Lacrimal sweating (due to postganglionic sympathetic deficit, often seen in Raeder's syndrome ) Harlequin syndrome Emotional hyperhidrosis Cancer [ edit ] A variety of cancers have been associated with the development of secondary hyperhidrosis including lymphoma , pheochromocytoma , carcinoid tumors (resulting in carcinoid syndrome ), and tumors within the thoracic cavity . [3] Endocrine [ edit ] Certain endocrine conditions are also known to cause secondary hyperhidrosis including diabetes mellitus (especially when blood sugars are low ), acromegaly , hyperpituitarism , and various forms of thyroid disease . [3] Medications [ edit ] Use of selective serotonin reuptake inhibitors (e.g., sertraline ) is a common cause of medication-induced secondary hyperhidrosis. [3] Other medications associated with secondary hyperhidrosis include tricyclic antidepressants , opioids , nonsteroidal anti-inflammatory drugs (NSAIDs), glyburide , insulin , anxiolytic agents, adrenergic agonists , and cholinergic agonists . [3] Miscellaneous [ edit ] In people with a past history of spinal cord injuries Autonomic dysreflexia Orthostatic hypotension Posttraumatic syringomyelia Associated with peripheral neuropathies Familial dysautonomia ( Riley-Day syndrome ) Congenital autonomic dysfunction with universal pain loss Exposure to cold, notably associated with cold-induced sweating syndrome Associated with probable brain lesions Episodic with hypothermia ( Hines and Bannick syndrome ) Episodic without hypothermia Olfactory Associated with systemic medical problems Parkinson's disease Fibromyalgia Congestive heart failure Anxiety Obesity Menopausal state Night sweats Compensatory Infantile acrodynia induced by chronic low-dose mercury exposure, leading to elevated catecholamine accumulation and resulting in a clinical picture resembling pheochromocytoma . ... Major problems with compensatory sweating are seen in 20–80% of patients undergoing the surgery. [36] [37] [38] Most people find the compensatory sweating to be tolerable while 1–51% claim that their quality of life decreased as a result of compensatory sweating ." [31] Total body perspiration in response to heat has been reported to increase after sympathectomy. [39] The original sweating problem may recur due to nerve regeneration, sometimes as early as 6 months after the procedure. [36] [37] [40] Other possible side-effects include Horner's Syndrome (about 1%), gustatory sweating (less than 25%) and excessive dryness of the palms (sandpaper hands). [41] Some patients have experienced cardiac sympathetic denervation, which can result in a 10% decrease in heart rate both at rest and during exercise, resulting in decreased exercise tolerance. [42] Percutaneous sympathectomy is a minimally invasive procedure similar to the botulinum method, in which nerves are blocked by an injection of phenol . [43] The procedure provides temporary relief in most cases.BIRC3, SCN11A, SRCAP, AGPAT2, GNA14, PLAA, CRLF1, AIP, PHOX2B, BCL10, SUCLG1, SERPINB7, CDK13, ELP1, IKBKG, CUL4B, VHL, UCP2, TP53, THPO, TERT, TERC, MLX, HNF1A, TAT, ABCC8, SPR, MALT1, KIF1B, ASCL1, CLCF1, CAVIN1, NLRP3, LONP2, GPR101, CTC1, USB1, WNK1, KLC2, CDH23, NLRC4, SLURP1, NGLY1, TMEM127, NHP2, NOP10, WRAP53, MAGEL2, RETREG1, RTEL1, SEPSECS, FOXP1, BSCL2, TINF2, PTPN22, FLRT1, SLCO2A1, SLC18A2, SLC12A3, SDHD, IGH, HPGD, HNF4A, HMBS, HLA-B, HINT1, HEXB, GDNF, GABRA3, FUCA1, FOS, FGFR3, EDN3, DKC1, DDC, CTSB, COL6A3, COL6A2, COL6A1, CLCNKB, CAV1, CACNA1S, DST, BLM, KIF1A, IGHMBP2, IL12B, JAK2, MEN1, SDHC, SDHB, SCN9A, RET, PSMB8, PRNP, MAP2K2, MAP2K1, PPARG, PARN, MPL, MAX, JUP, LIFR, KRT17, KRT16, KRT14, KRT9, KRT6B, KRT6A, KRT5, KRT1, KCNJ11, KCNA1, KCNJ18
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Nicotine Poisoning
Wikipedia
External links [ edit ] Classification D ICD - 10 : F17 .0, T65.2 DiseasesDB : 30389 External resources MedlinePlus : 002510 v t e Psychoactive substance-related disorder General SID Substance intoxication / Drug overdose Substance-induced psychosis Withdrawal : Craving Neonatal withdrawal Post-acute-withdrawal syndrome (PAWS) SUD Substance abuse / Substance-related disorders Physical dependence / Psychological dependence / Substance dependence Combined substance use SUD Polysubstance dependence SID Combined drug intoxication (CDI) Alcohol SID Cardiovascular diseases Alcoholic cardiomyopathy Alcohol flush reaction (AFR) Gastrointestinal diseases Alcoholic liver disease (ALD): Alcoholic hepatitis Auto-brewery syndrome (ABS) Endocrine diseases Alcoholic ketoacidosis (AKA) Nervous system diseases Alcohol-related dementia (ARD) Alcohol intoxication Hangover Neurological disorders Alcoholic hallucinosis Alcoholic polyneuropathy Alcohol-related brain damage Alcohol withdrawal syndrome (AWS): Alcoholic hallucinosis Delirium tremens (DTs) Fetal alcohol spectrum disorder (FASD) Fetal alcohol syndrome (FAS) Korsakoff syndrome Positional alcohol nystagmus (PAN) Wernicke–Korsakoff syndrome (WKS, Korsakoff psychosis) Wernicke encephalopathy (WE) Respiratory tract diseases Alcohol-induced respiratory reactions Alcoholic lung disease SUD Alcoholism (alcohol use disorder (AUD)) Binge drinking Caffeine SID Caffeine-induced anxiety disorder Caffeine-induced sleep disorder Caffeinism SUD Caffeine dependence Cannabis SID Cannabis arteritis Cannabinoid hyperemesis syndrome (CHS) SUD Amotivational syndrome Cannabis use disorder (CUD) Synthetic cannabinoid use disorder Cocaine SID Cocaine intoxication Prenatal cocaine exposure (PCE) SUD Cocaine dependence Hallucinogen SID Acute intoxication from hallucinogens (bad trip) Hallucinogen persisting perception disorder (HPPD) Nicotine SID Nicotine poisoning Nicotine withdrawal SUD Nicotine dependence Opioids SID Opioid overdose SUD Opioid use disorder (OUD) Sedative / hypnotic SID Kindling (sedative–hypnotic withdrawal) benzodiazepine : SID Benzodiazepine overdose Benzodiazepine withdrawal SUD Benzodiazepine use disorder (BUD) Benzodiazepine dependence barbiturate : SID Barbiturate overdose SUD Barbiturate dependence Stimulants SID Stimulant psychosis amphetamine : SUD Amphetamine dependence Volatile solvent SID Sudden sniffing death syndrome (SSDS) Toluene toxicity SUD Inhalant abuse v t e Poisoning Toxicity Overdose History of poison Inorganic Metals Toxic metals Beryllium Cadmium Lead Mercury Nickel Silver Thallium Tin Dietary minerals Chromium Cobalt Copper Iron Manganese Zinc Metalloids Arsenic Nonmetals Sulfuric acid Selenium Chlorine Fluoride Organic Phosphorus Pesticides Aluminium phosphide Organophosphates Nitrogen Cyanide Nicotine Nitrogen dioxide poisoning CHO alcohol Ethanol Ethylene glycol Methanol Carbon monoxide Oxygen Toluene Pharmaceutical Drug overdoses Nervous Anticholinesterase Aspirin Barbiturates Benzodiazepines Cocaine Lithium Opioids Paracetamol Tricyclic antidepressants Cardiovascular Digoxin Dipyridamole Vitamin poisoning Vitamin A Vitamin D Vitamin E Megavitamin-B 6 syndrome Biological 1 Fish / seafood Ciguatera Haff disease Ichthyoallyeinotoxism Scombroid Shellfish poisoning Amnesic Diarrhetic Neurotoxic Paralytic Other vertebrates amphibian venom Batrachotoxin Bombesin Bufotenin Physalaemin birds / quail Coturnism snake venom Alpha-Bungarotoxin Ancrod Batroxobin Arthropods Arthropod bites and stings bee sting / bee venom Apamin Melittin scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism Loxoscelism tick paralysis Plants / fungi Cinchonism Ergotism Lathyrism Locoism Mushrooms Strychnine 1 including venoms , toxins , foodborne illnesses .
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Herpes Labialis
Wikipedia
External links Classification D ICD - 10 : B00.1 ICD - 9-CM : 054.9 MeSH : D006560 v t e Skin infections , symptoms and signs related to viruses DNA virus Herpesviridae Alpha HSV Herpes simplex Herpetic whitlow Herpes gladiatorum Herpes simplex keratitis Herpetic sycosis Neonatal herpes simplex Herpes genitalis Herpes labialis Eczema herpeticum Herpetiform esophagitis Herpes B virus B virus infection VZV Chickenpox Herpes zoster Herpes zoster oticus Ophthalmic zoster Disseminated herpes zoster Zoster-associated pain Modified varicella-like syndrome Beta Human herpesvirus 6 / Roseolovirus Exanthema subitum Roseola vaccinia Cytomegalic inclusion disease Gamma KSHV Kaposi's sarcoma Poxviridae Ortho Variola Smallpox Alastrim MoxV Monkeypox CPXV Cowpox VV Vaccinia Generalized vaccinia Eczema vaccinatum Progressive vaccinia Buffalopox Para Farmyard pox : Milker's nodule Bovine papular stomatitis Pseudocowpox Orf Sealpox Other Yatapoxvirus : Tanapox Yaba monkey tumor virus MCV Molluscum contagiosum Papillomaviridae HPV Wart / plantar wart Heck's disease Genital wart giant Laryngeal papillomatosis Butcher's wart Bowenoid papulosis Epidermodysplasia verruciformis Verruca plana Pigmented wart Verrucae palmares et plantares BPV Equine sarcoid Parvoviridae Parvovirus B19 Erythema infectiosum Reticulocytopenia Papular purpuric gloves and socks syndrome Polyomaviridae Merkel cell polyomavirus Merkel cell carcinoma RNA virus Paramyxoviridae MeV Measles Togaviridae Rubella virus Rubella Congenital rubella syndrome ("German measles" ) Alphavirus infection Chikungunya fever Picornaviridae CAV Hand, foot, and mouth disease Herpangina FMDV Foot-and-mouth disease Boston exanthem disease Ungrouped Asymmetric periflexural exanthem of childhood Post-vaccination follicular eruption Lipschütz ulcer Eruptive pseudoangiomatosis Viral-associated trichodysplasia Gianotti–Crosti syndrome v t e Oral and maxillofacial pathology Lips Cheilitis Actinic Angular Plasma cell Cleft lip Congenital lip pit Eclabium Herpes labialis Macrocheilia Microcheilia Nasolabial cyst Sun poisoning Trumpeter's wart Tongue Ankyloglossia Black hairy tongue Caviar tongue Crenated tongue Cunnilingus tongue Fissured tongue Foliate papillitis Glossitis Geographic tongue Median rhomboid glossitis Transient lingual papillitis Glossoptosis Hypoglossia Lingual thyroid Macroglossia Microglossia Rhabdomyoma Palate Bednar's aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Torus palatinus Oral mucosa – Lining of mouth Amalgam tattoo Angina bullosa haemorrhagica Behçet's disease Bohn's nodules Burning mouth syndrome Candidiasis Condyloma acuminatum Darier's disease Epulis fissuratum Erythema multiforme Erythroplakia Fibroma Giant-cell Focal epithelial hyperplasia Fordyce spots Hairy leukoplakia Hand, foot and mouth disease Hereditary benign intraepithelial dyskeratosis Herpangina Herpes zoster Intraoral dental sinus Leukoedema Leukoplakia Lichen planus Linea alba Lupus erythematosus Melanocytic nevus Melanocytic oral lesion Molluscum contagiosum Morsicatio buccarum Oral cancer Benign: Squamous cell papilloma Keratoacanthoma Malignant: Adenosquamous carcinoma Basaloid squamous carcinoma Mucosal melanoma Spindle cell carcinoma Squamous cell carcinoma Verrucous carcinoma Oral florid papillomatosis Oral melanosis Smoker's melanosis Pemphigoid Benign mucous membrane Pemphigus Plasmoacanthoma Stomatitis Aphthous Denture-related Herpetic Smokeless tobacco keratosis Submucous fibrosis Ulceration Riga–Fede disease Verruca vulgaris Verruciform xanthoma White sponge nevus Teeth ( pulp , dentin , enamel ) Amelogenesis imperfecta Ankylosis Anodontia Caries Early childhood caries Concrescence Failure of eruption of teeth Dens evaginatus Talon cusp Dentin dysplasia Dentin hypersensitivity Dentinogenesis imperfecta Dilaceration Discoloration Ectopic enamel Enamel hypocalcification Enamel hypoplasia Turner's hypoplasia Enamel pearl Fluorosis Fusion Gemination Hyperdontia Hypodontia Maxillary lateral incisor agenesis Impaction Wisdom tooth impaction Macrodontia Meth mouth Microdontia Odontogenic tumors Keratocystic odontogenic tumour Odontoma Dens in dente Open contact Premature eruption Neonatal teeth Pulp calcification Pulp stone Pulp canal obliteration Pulp necrosis Pulp polyp Pulpitis Regional odontodysplasia Resorption Shovel-shaped incisors Supernumerary root Taurodontism Trauma Avulsion Cracked tooth syndrome Vertical root fracture Occlusal Tooth loss Edentulism Tooth wear Abrasion Abfraction Acid erosion Attrition Periodontium ( gingiva , periodontal ligament , cementum , alveolus ) – Gums and tooth-supporting structures Cementicle Cementoblastoma Gigantiform Cementoma Eruption cyst Epulis Pyogenic granuloma Congenital epulis Gingival enlargement Gingival cyst of the adult Gingival cyst of the newborn Gingivitis Desquamative Granulomatous Plasma cell Hereditary gingival fibromatosis Hypercementosis Hypocementosis Linear gingival erythema Necrotizing periodontal diseases Acute necrotizing ulcerative gingivitis Pericoronitis Peri-implantitis Periodontal abscess Periodontal trauma Periodontitis Aggressive As a manifestation of systemic disease Chronic Perio-endo lesion Teething Periapical, mandibular and maxillary hard tissues – Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic : periapical Dentigerous Buccal bifurcation Lateral periodontal Globulomaxillary Calcifying odontogenic Glandular odontogenic Non-odontogenic: Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Osteomyelitis Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget's disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis Temporomandibular joints , muscles of mastication and malocclusions – Jaw joints, chewing muscles and bite abnormalities Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overeruption Overjet Prognathia Retrognathia Scissor bite Maxillary hypoplasia Temporomandibular joint dysfunction Salivary glands Benign lymphoepithelial lesion Ectopic salivary gland tissue Frey's syndrome HIV salivary gland disease Necrotizing sialometaplasia Mucocele Ranula Pneumoparotitis Salivary duct stricture Salivary gland aplasia Salivary gland atresia Salivary gland diverticulum Salivary gland fistula Salivary gland hyperplasia Salivary gland hypoplasia Salivary gland neoplasms Benign: Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: Acinic cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Carcinoma ex pleomorphic adenoma Lymphoma Mucoepidermoid carcinoma Sclerosing polycystic adenosis Sialadenitis Parotitis Chronic sclerosing sialadenitis Sialectasis Sialocele Sialodochitis Sialosis Sialolithiasis Sjögren's syndrome Orofacial soft tissues – Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig's angina Macrostomia Melkersson–Rosenthal syndrome Microstomia Noma Oral Crohn's disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans Other Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic disease
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Group A Streptococcal Infection
Wikipedia
These occurs when the bacterium is able to infect areas where bacteria are not usually found, such as blood and organs . [7] The diseases that may be caused as a result of this include streptococcal toxic shock syndrome (STSS), necrotizing fasciitis (NF), pneumonia , and bacteremia . [3] In addition, infection of GAS may lead to further complications and health conditions, namely acute rheumatic fever and poststreptococcal glomerulonephritis . ... In cases of streptococcal toxic shock syndrome, treatment consists of penicillin and clindamycin, given with intravenous immunoglobulin. [ citation needed ] For toxic shock syndrome and necrotizing fasciitis, high-dose penicillin and clindamycin are used. ... PANDAS [ edit ] Obsessive–compulsive disorder and tic disorders are hypothesized to arise in a subset of children as a result of a post- streptococcal autoimmune process. [32] [33] [34] Its potential effect was described in 1998 by the controversial hypothesis called PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections), a condition thought to be triggered by GABHS infections. [32] [34] [35] The PANDAS hypothesis is unconfirmed and unsupported by data, and two new categories have been proposed: PANS (pediatric acute-onset neuropsychiatric syndrome) and CANS (childhood acute neuropsychiatric syndrome). [33] [34] The CANS/PANS hypotheses include different possible mechanisms underlying acute-onset neuropsychiatric conditions, but do not exclude GABHS infections as a cause in a subset of individuals. [33] [34] PANDAS, PANS and CANS are the focus of clinical and laboratory research but remain unproven. [32] [33] [34] References [ edit ] ^ Tanaka D, Isobe J, Watahiki M, Nagai Y, Katsukawa C, Kawahara R, Endoh M, Okuno R, Kumagai N, Matsumoto M, Morikawa Y, Ikebe T, Watanabe H (2008). ... Retrieved 2008-05-09 . ^ Guidelines for management of contacts of cases of invasive group A streptococcal disease (GAS) including streptococcal toxic shock syndrome (STSS) and necrotising fasciitis. ... "CANS: Childhood acute neuropsychiatric syndromes". Eur J Paediatr Neurol (Review). 22 (2): 316–320. doi : 10.1016/j.ejpn.2018.01.011 .
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Central Serous Retinopathy
Wikipedia
Thus indicating the steroid was the probable cause of the CSR. [12] A study of 60 persons with Cushing's syndrome found CSR in 3 (5%). [13] Cushing's syndrome is characterized by very high cortisol levels. ... External links [ edit ] Classification D ICD - 10 : H35.7 ICD - 9-CM : 362.41 MeSH : D056833 DiseasesDB : 31277 External resources MedlinePlus : 001612 eMedicine : oph/689 v t e Diseases of the human eye Adnexa Eyelid Inflammation Stye Chalazion Blepharitis Entropion Ectropion Lagophthalmos Blepharochalasis Ptosis Blepharophimosis Xanthelasma Ankyloblepharon Eyelash Trichiasis Madarosis Lacrimal apparatus Dacryoadenitis Epiphora Dacryocystitis Xerophthalmia Orbit Exophthalmos Enophthalmos Orbital cellulitis Orbital lymphoma Periorbital cellulitis Conjunctiva Conjunctivitis allergic Pterygium Pseudopterygium Pinguecula Subconjunctival hemorrhage Globe Fibrous tunic Sclera Scleritis Episcleritis Cornea Keratitis herpetic acanthamoebic fungal Exposure Photokeratitis Corneal ulcer Thygeson's superficial punctate keratopathy Corneal dystrophy Fuchs' Meesmann Corneal ectasia Keratoconus Pellucid marginal degeneration Keratoglobus Terrien's marginal degeneration Post-LASIK ectasia Keratoconjunctivitis sicca Corneal opacity Corneal neovascularization Kayser–Fleischer ring Haab's striae Arcus senilis Band keratopathy Vascular tunic Iris Ciliary body Uveitis Intermediate uveitis Hyphema Rubeosis iridis Persistent pupillary membrane Iridodialysis Synechia Choroid Choroideremia Choroiditis Chorioretinitis Lens Cataract Congenital cataract Childhood cataract Aphakia Ectopia lentis Retina Retinitis Chorioretinitis Cytomegalovirus retinitis Retinal detachment Retinoschisis Ocular ischemic syndrome / Central retinal vein occlusion Central retinal artery occlusion Branch retinal artery occlusion Retinopathy diabetic hypertensive Purtscher's of prematurity Bietti's crystalline dystrophy Coats' disease Sickle cell Macular degeneration Retinitis pigmentosa Retinal haemorrhage Central serous retinopathy Macular edema Epiretinal membrane (Macular pucker) Vitelliform macular dystrophy Leber's congenital amaurosis Birdshot chorioretinopathy Other Glaucoma / Ocular hypertension / Primary juvenile glaucoma Floater Leber's hereditary optic neuropathy Red eye Globe rupture Keratomycosis Phthisis bulbi Persistent fetal vasculature / Persistent hyperplastic primary vitreous Persistent tunica vasculosa lentis Familial exudative vitreoretinopathy Pathways Optic nerve Optic disc Optic neuritis optic papillitis Papilledema Foster Kennedy syndrome Optic atrophy Optic disc drusen Optic neuropathy Ischemic anterior (AION) posterior (PION) Kjer's Leber's hereditary Toxic and nutritional Strabismus Extraocular muscles Binocular vision Accommodation Paralytic strabismus Ophthalmoparesis Chronic progressive external ophthalmoplegia Kearns–Sayre syndrome palsies Oculomotor (III) Fourth-nerve (IV) Sixth-nerve (VI) Other strabismus Esotropia / Exotropia Hypertropia Heterophoria Esophoria Exophoria Cyclotropia Brown's syndrome Duane syndrome Other binocular Conjugate gaze palsy Convergence insufficiency Internuclear ophthalmoplegia One and a half syndrome Refraction Refractive error Hyperopia Myopia Astigmatism Anisometropia / Aniseikonia Presbyopia Vision disorders Blindness Amblyopia Leber's congenital amaurosis Diplopia Scotoma Color blindness Achromatopsia Dichromacy Monochromacy Nyctalopia Oguchi disease Blindness / Vision loss / Visual impairment Anopsia Hemianopsia binasal bitemporal homonymous Quadrantanopia subjective Asthenopia Hemeralopia Photophobia Scintillating scotoma Pupil Anisocoria Argyll Robertson pupil Marcus Gunn pupil Adie syndrome Miosis Mydriasis Cycloplegia Parinaud's syndrome Other Nystagmus Childhood blindness Infections Trachoma OnchocerciasisNR3C2, CD44, PROM1, PLXNA2, ALDH1A1, CTNNB1, SOX2, CD24, FOXM1, EGFR, ERBB2, POU5F1, POU5F1P3, POU5F1P4, BECN1, VEGFA, NOTCH1, TNF, CFH, DNMT1, STAT3, HES1, SLC22A3, DYNC2H1, HDAC2, MAPK1, IL6, YAP1, PLG, NFATC3, OSM, SERPINE1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, AKT1, ALCAM, TP53, ZEB1, JAG1, LGR5, MIR145, MIR146A, MIR200C, NRP1, NMU, KAT7, STRAP, H4C8, H4C9, H4C3, RAD51AP1, H4C11, H4C12, H4C6, H4C4, H4C1, NES, H4C2, AHSA1, ATG7, TRAP1, ABCB6, TBPL1, ABCG2, GRAP2, KLF4, DCLK1, H4C5, OSMR, H4C13, H4C14, CLDN2, MBD2, ADM, KLF12, MIR155, CD109, RMDN2, SHISA3, DNAJB8, DNAJB1P1, ARMS2, MIR10B, MIR137, MIR150, MIR200B, CBX5, MIR203A, MIR21, MIR219A1, MIR23B, MIR31, MIR95, H4C15, MIR874, GATD3B, H4-16, ORAI1, FSD1L, AGBL2, CBX7, RNF19A, POLDIP2, SLC7A5, FBXO8, RMDN1, HDAC7, PINX1, RMDN3, FBXW7, SYBU, PAG1, KIF15, ACKR3, PCBP4, SPC25, WDR48, FBRS, FSD1, GATD3A, PRDX2, ADAM12, AIMP2, EIF4E, EZH2, F3, PTK2B, FGF5, FN1, GLI1, GSK3B, GSTM1, HDAC1, HMGB1, HOXB3, HSF1, HSPA4, DNAJB1, IFNB1, CXCL8, ITK, KIT, EGR3, DUSP5, DNMT3A, CAV1, AKT2, APC, AR, BAX, BMI1, BMP2, BMP7, BNIP3L, RUNX3, DDX3X, CDH5, CDK2, CREBBP, CRK, CRP, MAPK14, CSF2, DAB2, LAMC2, LGALS1, LOX, TGFB1, SMN2, SOX9, SOX15, SRF, AURKA, ADAM17, TEAD1, TERF2, TGM2, SLC16A1, TLR3, TRAF6, TWIST1, EZR, VIM, WIPF1, PCGF2, CXCR4, SMN1, SLC12A3, EPCAM, MAPK9, SMAD2, MMP11, COX2, NELL1, PECAM1, PLAT, MAPK3, MAPK8, MAP2K7, SLC3A2, PTEN, PTGS2, PTPRB, RAC1, OPN1LW, REN, SDC1, CXCL12, MTCO2P12
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Drug Overdose
Wikipedia
Alcohol legality Alcohol consumption Anabolic steroid legality Cannabis legality Annual use Lifetime use Cigarette consumption Cocaine legality Cocaine use Methamphetamine legality Opiates use Psilocybin mushrooms legality Salvia legality v t e Psychoactive substance-related disorder General SID Substance intoxication / Drug overdose Substance-induced psychosis Withdrawal : Craving Neonatal withdrawal Post-acute-withdrawal syndrome (PAWS) SUD Substance abuse / Substance-related disorders Physical dependence / Psychological dependence / Substance dependence Combined substance use SUD Polysubstance dependence SID Combined drug intoxication (CDI) Alcohol SID Cardiovascular diseases Alcoholic cardiomyopathy Alcohol flush reaction (AFR) Gastrointestinal diseases Alcoholic liver disease (ALD): Alcoholic hepatitis Auto-brewery syndrome (ABS) Endocrine diseases Alcoholic ketoacidosis (AKA) Nervous system diseases Alcohol-related dementia (ARD) Alcohol intoxication Hangover Neurological disorders Alcoholic hallucinosis Alcoholic polyneuropathy Alcohol-related brain damage Alcohol withdrawal syndrome (AWS): Alcoholic hallucinosis Delirium tremens (DTs) Fetal alcohol spectrum disorder (FASD) Fetal alcohol syndrome (FAS) Korsakoff syndrome Positional alcohol nystagmus (PAN) Wernicke–Korsakoff syndrome (WKS, Korsakoff psychosis) Wernicke encephalopathy (WE) Respiratory tract diseases Alcohol-induced respiratory reactions Alcoholic lung disease SUD Alcoholism (alcohol use disorder (AUD)) Binge drinking Caffeine SID Caffeine-induced anxiety disorder Caffeine-induced sleep disorder Caffeinism SUD Caffeine dependence Cannabis SID Cannabis arteritis Cannabinoid hyperemesis syndrome (CHS) SUD Amotivational syndrome Cannabis use disorder (CUD) Synthetic cannabinoid use disorder Cocaine SID Cocaine intoxication Prenatal cocaine exposure (PCE) SUD Cocaine dependence Hallucinogen SID Acute intoxication from hallucinogens (bad trip) Hallucinogen persisting perception disorder (HPPD) Nicotine SID Nicotine poisoning Nicotine withdrawal SUD Nicotine dependence Opioids SID Opioid overdose SUD Opioid use disorder (OUD) Sedative / hypnotic SID Kindling (sedative–hypnotic withdrawal) benzodiazepine : SID Benzodiazepine overdose Benzodiazepine withdrawal SUD Benzodiazepine use disorder (BUD) Benzodiazepine dependence barbiturate : SID Barbiturate overdose SUD Barbiturate dependence Stimulants SID Stimulant psychosis amphetamine : SUD Amphetamine dependence Volatile solvent SID Sudden sniffing death syndrome (SSDS) Toluene toxicity SUD Inhalant abuse v t e Poisoning Toxicity Overdose History of poison Inorganic Metals Toxic metals Beryllium Cadmium Lead Mercury Nickel Silver Thallium Tin Dietary minerals Chromium Cobalt Copper Iron Manganese Zinc Metalloids Arsenic Nonmetals Sulfuric acid Selenium Chlorine Fluoride Organic Phosphorus Pesticides Aluminium phosphide Organophosphates Nitrogen Cyanide Nicotine Nitrogen dioxide poisoning CHO alcohol Ethanol Ethylene glycol Methanol Carbon monoxide Oxygen Toluene Pharmaceutical Drug overdoses Nervous Anticholinesterase Aspirin Barbiturates Benzodiazepines Cocaine Lithium Opioids Paracetamol Tricyclic antidepressants Cardiovascular Digoxin Dipyridamole Vitamin poisoning Vitamin A Vitamin D Vitamin E Megavitamin-B 6 syndrome Biological 1 Fish / seafood Ciguatera Haff disease Ichthyoallyeinotoxism Scombroid Shellfish poisoning Amnesic Diarrhetic Neurotoxic Paralytic Other vertebrates amphibian venom Batrachotoxin Bombesin Bufotenin Physalaemin birds / quail Coturnism snake venom Alpha-Bungarotoxin Ancrod Batroxobin Arthropods Arthropod bites and stings bee sting / bee venom Apamin Melittin scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism Loxoscelism tick paralysis Plants / fungi Cinchonism Ergotism Lathyrism Locoism Mushrooms Strychnine 1 including venoms , toxins , foodborne illnesses .
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Oral Submucous Fibrosis
Wikipedia
External links [ edit ] Classification D ICD - 10 : K13.5 MeSH : D009914 DiseasesDB : 33590 SNOMED CT : 32883009 External resources Orphanet : 357154 v t e Diseases of the skin and appendages by morphology Growths Epidermal Wart Callus Seborrheic keratosis Acrochordon Molluscum contagiosum Actinic keratosis Squamous-cell carcinoma Basal-cell carcinoma Merkel-cell carcinoma Nevus sebaceous Trichoepithelioma Pigmented Freckles Lentigo Melasma Nevus Melanoma Dermal and subcutaneous Epidermal inclusion cyst Hemangioma Dermatofibroma (benign fibrous histiocytoma) Keloid Lipoma Neurofibroma Xanthoma Kaposi's sarcoma Infantile digital fibromatosis Granular cell tumor Leiomyoma Lymphangioma circumscriptum Myxoid cyst Rashes With epidermal involvement Eczematous Contact dermatitis Atopic dermatitis Seborrheic dermatitis Stasis dermatitis Lichen simplex chronicus Darier's disease Glucagonoma syndrome Langerhans cell histiocytosis Lichen sclerosus Pemphigus foliaceus Wiskott–Aldrich syndrome Zinc deficiency Scaling Psoriasis Tinea ( Corporis Cruris Pedis Manuum Faciei ) Pityriasis rosea Secondary syphilis Mycosis fungoides Systemic lupus erythematosus Pityriasis rubra pilaris Parapsoriasis Ichthyosis Blistering Herpes simplex Herpes zoster Varicella Bullous impetigo Acute contact dermatitis Pemphigus vulgaris Bullous pemphigoid Dermatitis herpetiformis Porphyria cutanea tarda Epidermolysis bullosa simplex Papular Scabies Insect bite reactions Lichen planus Miliaria Keratosis pilaris Lichen spinulosus Transient acantholytic dermatosis Lichen nitidus Pityriasis lichenoides et varioliformis acuta Pustular Acne vulgaris Acne rosacea Folliculitis Impetigo Candidiasis Gonococcemia Dermatophyte Coccidioidomycosis Subcorneal pustular dermatosis Hypopigmented Tinea versicolor Vitiligo Pityriasis alba Postinflammatory hyperpigmentation Tuberous sclerosis Idiopathic guttate hypomelanosis Leprosy Hypopigmented mycosis fungoides Without epidermal involvement Red Blanchable Erythema Generalized Drug eruptions Viral exanthems Toxic erythema Systemic lupus erythematosus Localized Cellulitis Abscess Boil Erythema nodosum Carcinoid syndrome Fixed drug eruption Specialized Urticaria Erythema ( Multiforme Migrans Gyratum repens Annulare centrifugum Ab igne ) Nonblanchable Purpura Macular Thrombocytopenic purpura Actinic/solar purpura Papular Disseminated intravascular coagulation Vasculitis Indurated Scleroderma / morphea Granuloma annulare Lichen sclerosis et atrophicus Necrobiosis lipoidica Miscellaneous disorders Ulcers Hair Telogen effluvium Androgenic alopecia Alopecia areata Systemic lupus erythematosus Tinea capitis Loose anagen syndrome Lichen planopilaris Folliculitis decalvans Acne keloidalis nuchae Nail Onychomycosis Psoriasis Paronychia Ingrown nail Mucous membrane Aphthous stomatitis Oral candidiasis Lichen planus Leukoplakia Pemphigus vulgaris Mucous membrane pemphigoid Cicatricial pemphigoid Herpesvirus Coxsackievirus Syphilis Systemic histoplasmosis Squamous-cell carcinoma v t e Oral and maxillofacial pathology Lips Cheilitis Actinic Angular Plasma cell Cleft lip Congenital lip pit Eclabium Herpes labialis Macrocheilia Microcheilia Nasolabial cyst Sun poisoning Trumpeter's wart Tongue Ankyloglossia Black hairy tongue Caviar tongue Crenated tongue Cunnilingus tongue Fissured tongue Foliate papillitis Glossitis Geographic tongue Median rhomboid glossitis Transient lingual papillitis Glossoptosis Hypoglossia Lingual thyroid Macroglossia Microglossia Rhabdomyoma Palate Bednar's aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Torus palatinus Oral mucosa – Lining of mouth Amalgam tattoo Angina bullosa haemorrhagica Behçet's disease Bohn's nodules Burning mouth syndrome Candidiasis Condyloma acuminatum Darier's disease Epulis fissuratum Erythema multiforme Erythroplakia Fibroma Giant-cell Focal epithelial hyperplasia Fordyce spots Hairy leukoplakia Hand, foot and mouth disease Hereditary benign intraepithelial dyskeratosis Herpangina Herpes zoster Intraoral dental sinus Leukoedema Leukoplakia Lichen planus Linea alba Lupus erythematosus Melanocytic nevus Melanocytic oral lesion Molluscum contagiosum Morsicatio buccarum Oral cancer Benign: Squamous cell papilloma Keratoacanthoma Malignant: Adenosquamous carcinoma Basaloid squamous carcinoma Mucosal melanoma Spindle cell carcinoma Squamous cell carcinoma Verrucous carcinoma Oral florid papillomatosis Oral melanosis Smoker's melanosis Pemphigoid Benign mucous membrane Pemphigus Plasmoacanthoma Stomatitis Aphthous Denture-related Herpetic Smokeless tobacco keratosis Submucous fibrosis Ulceration Riga–Fede disease Verruca vulgaris Verruciform xanthoma White sponge nevus Teeth ( pulp , dentin , enamel ) Amelogenesis imperfecta Ankylosis Anodontia Caries Early childhood caries Concrescence Failure of eruption of teeth Dens evaginatus Talon cusp Dentin dysplasia Dentin hypersensitivity Dentinogenesis imperfecta Dilaceration Discoloration Ectopic enamel Enamel hypocalcification Enamel hypoplasia Turner's hypoplasia Enamel pearl Fluorosis Fusion Gemination Hyperdontia Hypodontia Maxillary lateral incisor agenesis Impaction Wisdom tooth impaction Macrodontia Meth mouth Microdontia Odontogenic tumors Keratocystic odontogenic tumour Odontoma Dens in dente Open contact Premature eruption Neonatal teeth Pulp calcification Pulp stone Pulp canal obliteration Pulp necrosis Pulp polyp Pulpitis Regional odontodysplasia Resorption Shovel-shaped incisors Supernumerary root Taurodontism Trauma Avulsion Cracked tooth syndrome Vertical root fracture Occlusal Tooth loss Edentulism Tooth wear Abrasion Abfraction Acid erosion Attrition Periodontium ( gingiva , periodontal ligament , cementum , alveolus ) – Gums and tooth-supporting structures Cementicle Cementoblastoma Gigantiform Cementoma Eruption cyst Epulis Pyogenic granuloma Congenital epulis Gingival enlargement Gingival cyst of the adult Gingival cyst of the newborn Gingivitis Desquamative Granulomatous Plasma cell Hereditary gingival fibromatosis Hypercementosis Hypocementosis Linear gingival erythema Necrotizing periodontal diseases Acute necrotizing ulcerative gingivitis Pericoronitis Peri-implantitis Periodontal abscess Periodontal trauma Periodontitis Aggressive As a manifestation of systemic disease Chronic Perio-endo lesion Teething Periapical, mandibular and maxillary hard tissues – Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic : periapical Dentigerous Buccal bifurcation Lateral periodontal Globulomaxillary Calcifying odontogenic Glandular odontogenic Non-odontogenic: Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Osteomyelitis Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget's disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis Temporomandibular joints , muscles of mastication and malocclusions – Jaw joints, chewing muscles and bite abnormalities Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overeruption Overjet Prognathia Retrognathia Scissor bite Maxillary hypoplasia Temporomandibular joint dysfunction Salivary glands Benign lymphoepithelial lesion Ectopic salivary gland tissue Frey's syndrome HIV salivary gland disease Necrotizing sialometaplasia Mucocele Ranula Pneumoparotitis Salivary duct stricture Salivary gland aplasia Salivary gland atresia Salivary gland diverticulum Salivary gland fistula Salivary gland hyperplasia Salivary gland hypoplasia Salivary gland neoplasms Benign: Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: Acinic cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Carcinoma ex pleomorphic adenoma Lymphoma Mucoepidermoid carcinoma Sclerosing polycystic adenosis Sialadenitis Parotitis Chronic sclerosing sialadenitis Sialectasis Sialocele Sialodochitis Sialosis Sialolithiasis Sjögren's syndrome Orofacial soft tissues – Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig's angina Macrostomia Melkersson–Rosenthal syndrome Microstomia Noma Oral Crohn's disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans Other Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic diseaseTGFB1, MMP9, ZEB1, PTGS2, COL1A2, TIMP1, MMP1, FGF2, MMP2, CST3, LOX, COL1A1, CTLA4, TNF, MICA, IL6, CXCL8, IFNG, TP53, CYP1A1, HIF1A, GSTT1, GSTM1, COX2, PPIA, SMN1, SMN2, MMP3, MTCO2P12, CYP2E1, ACTB, ENO1, EGR1, ERBB2, PPIG, GPRC5A, PABPN1, XRCC3, VIM, ANGPT1, BIRC5, FAS, TM7SF2, ZEB2, TGM2, FASLG, AR, CCND1, BMP4, EIF2AK3, WIF1, YAP1, CCL2, GAS5-AS1, LINC01672, MIR1246, MIR499A, MIR203A, MIR200C, MIR200B, GSTK1, CYCSP38, LINC00974, NCOA7, SLCO6A1, MED15, DKK3, TPSD1, SFRP4, S100A4, S100B, S100A1, TM4SF1, LUM, COMP, KRT19, CCN2, CTNNB1, HTC2, HMOX1, HLA-DRB1, CYP3A5, SERPIND1, EGF, CXCL1, FGFR2, FGFR3, SMAD2, MDM2, CXCL9, PLG, BRD2, RARRES1, PTMA, BMP7, PSMA1, BSG, SERPINE1, CD34, NOTCH4, NFKBIA, CA9, CALR, ABO, CASP8, NAT2
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Pleural Effusion
Wikipedia
Causes [ edit ] Pleural effusion Transudative [ edit ] The most common causes of transudative pleural effusion in the United States are heart failure and cirrhosis . Nephrotic syndrome , leading to the loss of large amounts of albumin in urine and resultant low albumin levels in the blood and reduced colloid osmotic pressure, is another less common cause of pleural effusion. ... The excessive interstitial lung fluid traverses the visceral pleura and accumulates in the pleural space . [ citation needed ] Conditions associated with transudative pleural effusions include: [2] Congestive heart failure Liver cirrhosis Severe hypoalbuminemia Nephrotic syndrome Acute atelectasis Myxedema Peritoneal dialysis Meigs's syndrome Obstructive uropathy End-stage kidney disease Exudative [ edit ] Pleural effusion Anteroposterior Chest X-ray of a pleural effusion. ... Conditions associated with exudative pleural effusions: [2] Parapneumonic effusion due to pneumonia Malignancy (either lung cancer or metastases to the pleura from elsewhere) Infection (empyema due to bacterial pneumonia) Trauma Pulmonary infarction Pulmonary embolism Autoimmune disorders Pancreatitis Ruptured esophagus ( Boerhaave's syndrome ) Rheumatoid pleurisy Drug-induced lupus Other/ungrouped [ edit ] Other causes of pleural effusion include tuberculosis (though stains of pleural fluid are only rarely positive for acid-fast bacilli, this is the most common cause of pleural effusions in some developing countries), autoimmune disease such as systemic lupus erythematosus , bleeding (often due to chest trauma), chylothorax (most commonly caused by trauma), and accidental infusion of fluids. [ citation needed ] Less common causes include esophageal rupture or pancreatic disease, intra-abdominal abscesses, rheumatoid arthritis , asbestos pleural effusion, mesothelioma , Meigs's syndrome (ascites and pleural effusion due to a benign ovarian tumor ), and ovarian hyperstimulation syndrome . [ citation needed ] Pleural effusions may also occur through medical or surgical interventions , including the use of medications (pleural fluid is usually eosinophilic ), coronary artery bypass surgery , abdominal surgery, endoscopic variceal sclerotherapy , radiation therapy , liver or lung transplantation , insertion of ventricular shunt as a treatment method of hydrocephalus, [4] [5] and intra- or extravascular insertion of central lines . [ citation needed ] Pathophysiology [ edit ] Pleural fluid is secreted by the parietal layer of the pleura and reabsorbed by the lymphatics in the most dependent parts of the parietal pleura, primarily the diaphragmatic and mediastinal regions. ... External links [ edit ] Classification D ICD - 10 : J90 - J91 ICD - 9-CM : 511.9 MeSH : D010996 SNOMED CT : 60046008 External resources MedlinePlus : 000086 MedlinePlus Encyclopedia : Pleural Effusion Pleural Effusion Images from MedPix v t e Diseases of the respiratory system Upper RT (including URTIs , common cold ) Head sinuses Sinusitis nose Rhinitis Vasomotor rhinitis Atrophic rhinitis Hay fever Nasal polyp Rhinorrhea nasal septum Nasal septum deviation Nasal septum perforation Nasal septal hematoma tonsil Tonsillitis Adenoid hypertrophy Peritonsillar abscess Neck pharynx Pharyngitis Strep throat Laryngopharyngeal reflux (LPR) Retropharyngeal abscess larynx Croup Laryngomalacia Laryngeal cyst Laryngitis Laryngopharyngeal reflux (LPR) Laryngospasm vocal cords Laryngopharyngeal reflux (LPR) Vocal fold nodule Vocal fold paresis Vocal cord dysfunction epiglottis Epiglottitis trachea Tracheitis Laryngotracheal stenosis Lower RT / lung disease (including LRTIs ) Bronchial / obstructive acute Acute bronchitis chronic COPD Chronic bronchitis Acute exacerbation of COPD ) Asthma ( Status asthmaticus Aspirin-induced Exercise-induced Bronchiectasis Cystic fibrosis unspecified Bronchitis Bronchiolitis Bronchiolitis obliterans Diffuse panbronchiolitis Interstitial / restrictive ( fibrosis ) External agents/ occupational lung disease Pneumoconiosis Aluminosis Asbestosis Baritosis Bauxite fibrosis Berylliosis Caplan's syndrome Chalicosis Coalworker's pneumoconiosis Siderosis Silicosis Talcosis Byssinosis Hypersensitivity pneumonitis Bagassosis Bird fancier's lung Farmer's lung Lycoperdonosis Other ARDS Combined pulmonary fibrosis and emphysema Pulmonary edema Löffler's syndrome / Eosinophilic pneumonia Respiratory hypersensitivity Allergic bronchopulmonary aspergillosis Hamman-Rich syndrome Idiopathic pulmonary fibrosis Sarcoidosis Vaping-associated pulmonary injury Obstructive / Restrictive Pneumonia / pneumonitis By pathogen Viral Bacterial Pneumococcal Klebsiella Atypical bacterial Mycoplasma Legionnaires' disease Chlamydiae Fungal Pneumocystis Parasitic noninfectious Chemical / Mendelson's syndrome Aspiration / Lipid By vector/route Community-acquired Healthcare-associated Hospital-acquired By distribution Broncho- Lobar IIP UIP DIP BOOP-COP NSIP RB Other Atelectasis circulatory Pulmonary hypertension Pulmonary embolism Lung abscess Pleural cavity / mediastinum Pleural disease Pleuritis/pleurisy Pneumothorax / Hemopneumothorax Pleural effusion Hemothorax Hydrothorax Chylothorax Empyema/pyothorax Malignant Fibrothorax Mediastinal disease Mediastinitis Mediastinal emphysema Other/general Respiratory failure Influenza Common cold SARS Coronavirus disease 2019 Idiopathic pulmonary haemosiderosis Pulmonary alveolar proteinosisTNF, SPP1, IL12A, IGH, MYD88, IL10, IL6, FAS, MEFV, FSHR, NLRP3, RIT1, LACC1, KIAA1109, GPR35, IL23R, PLVAP, CFH, HFE, HLA-B, HLA-DRB1, CD46, CCBE1, AARS2, PTPN11, EGFR, CFI, SOX18, ERAP1, PRSS2, PRSS1, PMM2, INHBA, KLRC4, IRAK1, CTRC, LBR, TAPT1, DNAH11, CCR1, TMEM151B, BMP2, BCL2, C1QA, C1R, C4A, CCND1, MST1, DNASE1L3, CFTR, TCF4, STAT4, SPINK1, BCL6, HELLPAR, IL12A-AS1, UBAC2, MIF, TLR4, VEGFA, CEACAM5, CRP, ADA, ALK, C20orf181, CD274, CDKN2A, PSG2, NCAM1, CEACAM3, MSLN, CEACAM7, NKX2-1, PDCD1, KRAS, CD44, BDNF, MUC1, CA9, HMGB1, SHOX2, IL33, TTF1, TLR2, CCL2, CTLA4, HACD1, EBAG9, CD83, TTR, KHSRP, BAP1, MKKS, KMT2D, AIMP2, BCAR1, TP53, TNFRSF1B, TK1, TIMP1, GRAP2, ACTB, PIEZO1, INTS2, COL18A1, MYO18B, AZIN2, ROMO1, BTLA, CACNA1G-AS1, GADL1, THEMIS, MIR130A, MIR198, MIR222, MIR93, CXADRP1, SFTPA1, SFTPA2, CD24, LINC01672, VTCN1, IL26, NR1I3, GINS2, TRIM13, CAP1, CXCL13, SORBS1, AHSA1, SEPTIN9, ESM1, FSTL1, PSIP1, WIF1, BRD4, RNF19A, POLDIP2, SIGLEC7, EML4, TERT, IL22, TG, CFP, TCF3, ERBB3, EFEMP1, FCGR3A, FCGR3B, FGF3, FGF4, FHIT, CXCR3, NR3C1, HCLS1, HNRNPA1, HP, HSD11B1, HSPA4, IFNB1, IGF1, IGFBP2, IL1B, ESAT, ERBB2, IL2RB, ENO2, AKT1, ALB, ARR3, BCR, BST1, CALR, CASR, CCR5, CLDN7, CRK, MAPK14, VCAN, CTAA1, CUX1, CXADR, ACE, EGF, IL2, IL5, ST2, MYH2, NRAS, NT5E, SERPINB6, PLG, PRKAR1A, MAPK1, ROS1, S100A8, S100A9, S100A11, CCL8, CCL17, SDC2, SRSF1, SRSF3, SRSF5, SPG7, NGF, MTAP, IL17A, MRC1, CXCL10, ANOS1, LAG3, LCN2, LDHA, LGALS1, LGALS9, LMNA, LNPEP, LUM, EPCAM, MCAM, MET, SCGB2A2, MIP, MMP2, MMP9, H3P10
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Preeclampsia/eclampsia 1
Omim
Lachmeijer et al. (2001) performed a genome scan including 293 polymorphic markers in 67 Dutch sib-pair families affected by preeclampsia, eclampsia, or HELLP syndrome. A total of 12 regions showed nominal lod score peaks (lod scores between 0.6 and 2.2), with the highest lod score of 1.99 on chromosome 12q at 109.5 cM. ... The authors suggested that this may indicate that HELLP syndrome has a different genetic background than preeclampsia, which they noted was in contrast to the consensus statement of the Australasian Society on the Study of Hypertension in Pregnancy (Brown et al., 2000), in which HEELP syndrome was classified as a severe form of preeclampsia. ... Using additional microsatellite markers, van Dijk et al. (2012) reanalyzed the cohort of 34 families with HELLP syndrome originally studied by Lachmeijer et al. (2001) and found that the lod score for the region on chromosome 12q23 increased from 2.1 to 2.37. ... No difference in the frequency of the polymorphism was found between groups who did or did not develop the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). ... Association with Coagulation Factor V Brenner et al. (1996) identified the factor V Leiden mutation (R506Q; 612309.0001) in 2 patients with the HELLP syndrome, and Kupferminc et al. (1999) found an association between that mutation and a variety of obstetrical complications, including preeclampsia.NOS3, STOX1, CORIN, FLT1, AGT, ACE, SERPINE1, EPHX1, EDN1, INHBA, CP, SCNN1A, HMOX1, ARHGAP45, DDAH2, ANXA5, ENG, LEP, PGF, LEPR, ICAM1, TLR3, CCL5, PTGS1, PDE5A, CYP2J2, C3, AKR1C3, COMT, IDO1, CD40LG, NOTCH2, ASB4, ITGA4, F5, CYP11B2, CFI, EED, HBA1, HBA2, PPARG, LBR, SOS1, CD46, GNAS, HELLPAR, CFH, NSD1, FGF14, SLC25A20, ADGRG6, CYP11B1, DHPS, ZMPSTE24, MYCBP2, ZNF295-AS1, TMEM94, KMT2B, AGTR1, ADM, VEGFA, IGFBP1, INHA, MTHFR, IL16, MMP9, MBL2, THBD, ERVW-1, SELP, ADIPOQ, TLR4, TNF, IL10, CSF1, PLAC1, GCM1, SYNPO, KIR3DL3, S100B, TAP1, TAC3, SOCS3, APLN, TDO2, SLC1A5, EBAG9, SELL, FLT1P1, SELE, CD24, TAP2, NOD2, TEK, PROZ, TFPI, ADAMTS13, TGFB1, ADAM12, VWF, VCAM1, LGALS13, NOX1, TIMP2, TPBG, TLR2, SERBP1, NAT2, REN, CGB3, SERPIND1, GSTP1, GH2, FABP4, F2, ESR1, EFNA1, CRP, CRH, CPB2, CLU, CHRNA7, TNFRSF8, PYGM, CALR, CALCA, BOK, BDKRB2, ANGPT2, APLNR, AGTR2, ADRB3, ADRB2, ADORA2B, ADA, ACVR2A, HDC, HIF1A, HLA-G, HP, PTX3, PSG5, HTRA1, PRCP, PON1, PEE1, ENPP1, OLR1, NPHS1, CCN3, NOS2, ACTG2, LGALS1, CXCL10, IL18, IL15, IL6ST, IL6, IL4, CCN1, IGF2, IGF1, IFNGR2, IFNG, HSD11B2, LIPC
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Mitochondrial Complex Ii Deficiency
Omim
Rivner et al. (1989) reported a 25-year-old woman with Kearns-Sayre syndrome (530000) and isolated complex II deficiency. ... Brain imaging showed symmetric foci of necrosis in the substantia nigra and basal ganglia typical of Leigh syndrome (256000). Mitochondria isolated from skeletal muscle, fibroblasts, and lymphocytes showed complex II deficiency. ... Molecular Genetics In 2 sibs with complex II deficiency presenting as Leigh syndrome reported by Bourgeois et al. (1992), Bourgeron et al. (1995) identified a homozygous mutation in the SDHA gene (600857.0001). ... INHERITANCE - Autosomal recessive GROWTH Height - Short stature Other - Poor growth HEAD & NECK Eyes - Ptosis - Ophthalmoplegia - Pigmentary retinopathy - Optic atrophy - Nystagmus - Impaired vision CARDIOVASCULAR Heart - Hypertrophic cardiomyopathy - Dilated cardiomyopathy - Left ventricular noncompaction SKELETAL - Joint contractures MUSCLE, SOFT TISSUES - Hypotonia, neonatal - Muscle weakness - Exercise intolerance - Ragged red fibers seen on muscle biopsy - Abnormal mitochondria with paracrystalline inclusions seen on muscle biopsy - Accumulated lipid droplets seen on muscle biopsy NEUROLOGIC Central Nervous System - Psychomotor regression in infants - Spasticity - Hyperreflexia - Extensor plantar responses - Ataxia - Cognitive impairment - Dystonia - Myoclonus - Seizures - Leukoencephalopathy, progressive - Spongiform encephalomyelopathy - Leigh syndrome ( 245000 ), in a subset of patients - Kearns-Sayre syndrome ( 530000 ), in a subset of patients METABOLIC FEATURES - Lactic acidosis may occur with stress or infection LABORATORY ABNORMALITIES - Decreased activity of mitochondrial complex II (succinate dehydrogenase) - Mildly increased serum lactate MISCELLANEOUS - Onset in first year of life - Highly variable phenotype MOLECULAR BASIS - Caused by mutation in the flavoprotein subunit of succinate dehydrogenase complex gene (SDHA, 600857.0001 ) - Caused by mutation in the succinate dehydrogenase complex assembly factor 1 gene (SDHAF1, 612848.0001 ) - Caused by mutation in the succinate dehydrogenase complex, subunit D, integral membrane protein gene (SDHD, 602690.0029 ) ▲ Close
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Hemochromatosis, Neonatal
Omim
Clinical Features Knisely et al. (1987) reviewed reported cases of neonatal hemochromatosis, applying rigid criteria as follows: a rapidly progressive clinical course with death in utero or in the early neonatal period; increased tissue iron deposition in multiple sites, particularly in the liver, pancreas, heart, and endocrine glands, with the extrahepatic reticuloendothelial system relatively unaffected; and no evidence for hemolytic disease, syndromes associated with hemosiderosis, or exogenous iron overload from transfusions. ... The authors noted that the clinical course and pathologic findings are distinct from those of Zellweger syndrome (see 214100), hereditary tyrosinemia (276700), and leprechaunism (246200), in which hepatic siderosis is also seen. ... Neonatal hemochromatosis also occurs as part of the neonatal lupus erythematosus syndrome, associated with maternal anti-Ro/SS-A (109092) and anti-Ro/SS-B (109090) autoantibodies. ... Schoenlebe et al. (1993) reported an experience indicating that neonatal hemochromatosis, also known as perinatal hemochromatosis or neonatal iron storage disease, can occur as part of neonatal lupus erythematosus syndrome (see 152700) associated with maternal anti-Ro/SSA (see 109092) and anti-La/SSB (109090) autoantibodies. They reported a 6-week-old girl with neonatal hemochromatosis whose mother had these autoantibodies associated with Sjogren syndrome (see 270150); an older child had congenital heart block.
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The Truman Show Delusion
Wikipedia
Part of a series on Psychology Outline History Subfields Basic types Abnormal Behavioral genetics Biological Cognitive / Cognitivism Comparative Cross-cultural Cultural Differential Developmental Evolutionary Experimental Mathematical Neuropsychology Personality Positive Quantitative Social Applied psychology Applied behavior analysis Clinical Community Consumer Counseling Critical Educational Environmental Ergonomics Forensic Health Humanistic Industrial and organizational Legal Medical Military Music Occupational health Political Religion School Sport Traffic Lists Disciplines Organizations Psychologists Psychotherapies Publications Research methods Theories Timeline Topics Psychology portal v t e The Truman Show delusion , informally known as Truman syndrome , is a type of delusion in which the person believes that their lives are staged reality shows , or that they are being watched on cameras. ... The Truman Show delusion is not officially recognized nor listed in the Diagnostic and Statistical Manual of the American Psychiatric Association . [1] Contents 1 Background 2 Delusions 2.1 Cultural impact 3 Reported cases 3.1 Truman Syndrome 4 Medical relevance 5 Filmmaker's reaction 6 See also 7 References Background [ edit ] Main article: The Truman Show Rapid expansion of technology raises questions about which delusions are possible and which ones are bizarre. ... My family and everyone I knew were and are actors in a script, a charade whose entire purpose is to make me the focus of the world's attention. [8] The choice of the name "Truman Show Delusion" by the Golds was influenced by the fact that three of the five patients Joel Gold initially treated for the syndrome explicitly linked their perceived experiences to the film. [8] Truman Syndrome [ edit ] In the United Kingdom, psychiatrists Paolo Fusar-Poli , Oliver Howes, Lucia Valmaggia and Philip McGuire of the Institute of Psychiatry in London described in the British Journal of Psychiatry what they referred to as the "Truman Syndrome": [A] preoccupying belief that the world had changed in some way that other people were aware of, which he interpreted as indicating he was the subject of a film and living in a film set (a ‘fabricated world’).
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Dysesthesia
Wikipedia
Dysesthesia may be seen in patients with Guillain–Barré syndrome . Dysesthesia is among symptoms of neuropathy (along with paresthesias , gait disturbance , weakness, and absent DTRs ). ... It's typically seen in Dejerine-Roussy syndrome with hemi-sensory loss and severe dysesthesia of the affected area. Fibromyalgia may cause dysesthesia in all areas of the body, but mostly the extremities. [ medical citation needed ] Diagnosis [ edit ] Differential diagnosis [ edit ] Although dysesthesia is similar to phantom limb syndrome, they should not be confused. In phantom limb, the sensation is present in an amputated or absent limb, while dysesthesia refers to discomfort or pain in a tissue that has not been removed or amputated. ... Prakash et al. found that many patients with burning mouth syndrome (BMS), one variant of occlusal dysesthesia, also report painful sensations in other parts of the body. Many of the patients with BMS met the classification of restless leg syndrome (RLS). About half of these patients also had a family history of RLS.
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Vaginal Disease
Wikipedia
It is frequently associated with Mayer-Rokitansky-Küstner-Hauser (MRKH) syndrome, in which the most common result is an absent uterus in conjunction with a deformed or missing vagina, despite the presence of normal ovaries and normal external genitalia. ... Retrieved June 3, 2014 . ^ Goldstein, Irwin (1 March 2004). "Persistent Sexual Arousal Syndrome" . Boston University Medical Campus Institute for Sexual Medicine . ... PMID 9880287 . v t e Female diseases of the pelvis and genitals Internal Adnexa Ovary Endometriosis of ovary Female infertility Anovulation Poor ovarian reserve Mittelschmerz Oophoritis Ovarian apoplexy Ovarian cyst Corpus luteum cyst Follicular cyst of ovary Theca lutein cyst Ovarian hyperstimulation syndrome Ovarian torsion Fallopian tube Female infertility Fallopian tube obstruction Hematosalpinx Hydrosalpinx Salpingitis Uterus Endometrium Asherman's syndrome Dysfunctional uterine bleeding Endometrial hyperplasia Endometrial polyp Endometriosis Endometritis Menstruation Flow Amenorrhoea Hypomenorrhea Oligomenorrhea Pain Dysmenorrhea PMS Timing Menometrorrhagia Menorrhagia Metrorrhagia Female infertility Recurrent miscarriage Myometrium Adenomyosis Parametrium Parametritis Cervix Cervical dysplasia Cervical incompetence Cervical polyp Cervicitis Female infertility Cervical stenosis Nabothian cyst General Hematometra / Pyometra Retroverted uterus Vagina Hematocolpos / Hydrocolpos Leukorrhea / Vaginal discharge Vaginitis Atrophic vaginitis Bacterial vaginosis Candidal vulvovaginitis Hydrocolpos Sexual dysfunction Dyspareunia Hypoactive sexual desire disorder Sexual arousal disorder Vaginismus Urogenital fistulas Ureterovaginal Vesicovaginal Obstetric fistula Rectovaginal fistula Prolapse Cystocele Enterocele Rectocele Sigmoidocele Urethrocele Vaginal bleeding Postcoital bleeding Other / general Pelvic congestion syndrome Pelvic inflammatory disease External Vulva Bartholin's cyst Kraurosis vulvae Vestibular papillomatosis Vulvitis Vulvodynia Clitoral hood or clitoris Persistent genital arousal disorder
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Social Communication Disorder
Wikipedia
While autistic children exhibit pragmatic language impairment, this type of communication disorder can also be found in individuals with other types of disorders including auditory processing disorders , neuropathies , encephalopathies and certain genetic disorders. [12] Prior to the release of the DSM-5, there was debate over the relationship between semantic pragmatic disorder and autistic disorder, as the clinical profile of semantic pragmatic disorder is often seen in children with high-functioning autism . [13] See also [ edit ] Alexithymia Asperger syndrome Attention deficit hyperactivity disorder (ADHD) Autism High-functioning autism Hyperlexia Nonverbal learning disorder PDD not otherwise specified Specific language impairment Speech and language pathology Speech and language pathology in school settings References [ edit ] ^ Evidence- based practice and Autism in schools (2nd ed.). ... Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/1469-7610.00114/full v t e Pervasive developmental disorders and autism spectrum Main Causes Comorbid conditions Epidemiology Heritability Societal and cultural aspects Medical model Therapies Diagnoses Autism spectrum ( High-functioning autism Classic autism Asperger syndrome Pervasive developmental disorder not otherwise specified Childhood disintegrative disorder Rett syndrome ) Related conditions Alexithymia Attention deficit hyperactivity disorder Anxiety disorder ( obsessive–compulsive disorder ) Late talker Epilepsy Fragile X syndrome Hyperlexia Savant syndrome Sensory processing disorder Intellectual disability Developmental coordination disorder Multiple complex developmental disorder Controversies Autism rights movement Autistic enterocolitis Facilitated communication MMR vaccine Rapid prompting method Thiomersal ( Chelation ) Diagnostic scales Gilliam Asperger's disorder scale Autism Diagnostic Observation Schedule Autism Diagnostic Interview Autism-spectrum quotient Childhood Autism Rating Scale Lists Autism-related topics Fictional characters Schools
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Malignant Narcissism
Wikipedia
Malignant narcissism is a psychological syndrome comprising an extreme mix of narcissism , antisocial behavior , aggression , and sadism . [1] Grandiose , and always ready to raise hostility levels, the malignant narcissist undermines families and organizations in which they are involved, and dehumanizes the people with whom they associate. [2] Malignant narcissism is a hypothetical, experimental diagnostic category. Narcissistic personality disorder is found in the Diagnostic and Statistical Manual of Mental Disorders ( DSM-IV-TR ), while malignant narcissism is not. As a hypothetical syndrome , malignant narcissism could include aspects of narcissistic personality disorder (NPD) alongside a mix of antisocial , paranoid and sadistic personality disorder traits. ... Kernberg described malignant narcissism [8] as a syndrome characterized by a narcissistic personality disorder (NPD), antisocial features, paranoid traits, and egosyntonic aggression . ... Since sadism is often considered a feature of malignant narcissism, an individual with the syndrome may not only lack feelings of guilt or remorse for hurting others but may even derive pleasure from the gratuitous infliction of mental or physical pain on others. ... External links [ edit ] Narcissism and co-morbidity with other disorders v t e Narcissism Types Collective Egomania Flying monkeys Healthy Malignant Narcissistic personality disorder Spiritual Workplace Characteristics Betrayal Boasting Egocentrism Egotism Empathy (lack of) Envy Entitlement (exaggerated sense of) Fantasy Grandiosity Hubris Magical thinking Manipulative Narcissistic abuse Narcissistic elation Narcissistic rage and narcissistic injury Narcissistic mortification Narcissistic supply Narcissistic withdrawal Perfectionism Self-esteem Self-righteousness Shamelessness Superficial charm Superiority complex True self and false self Vanity Defences Denial Idealization and devaluation Distortion Projection Splitting Cultural phenomena Control freak Don Juanism Dorian Gray syndrome My way or the highway Selfie Related articles Codependency Counterdependency Dark triad Ego ideal "Egomania" (film) Egotheism Empire-building God complex History of narcissism Messiah complex Micromanagement Narcissism of small differences Narcissistic leadership Narcissistic parent Narcissistic Personality Inventory Narcissus (mythology) On Narcissism Sam Vaknin Self-love Self-serving bias Spoiled child The Culture of Narcissism Workplace bullying
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Adenoma
Wikipedia
However, even though benign, they have the potential to cause serious health complications by compressing other structures ( mass effect ) and by producing large amounts of hormones in an unregulated, non-feedback-dependent manner (causing paraneoplastic syndromes ). Some adenomas are too small to be seen macroscopically but can still cause clinical symptoms. [ citation needed ] Contents 1 Histopathology 2 Locations 2.1 Colon 2.2 Renal 2.3 Adrenal 2.4 Thyroid 2.5 Pituitary 2.6 Parathyroid 2.7 Liver 2.8 Breast 2.9 Appendix 2.10 Bronchial 2.11 Sebaceous 2.12 Salivary glands 2.13 Prostate 3 Treatment 4 References 5 External links Histopathology [ edit ] Adenoma is a benign tumor of glandular tissue, such as the mucosa of stomach, small intestine, and colon, in which tumor cells form glands or gland like structures. ... While some adrenal adenomas do not secrete hormones at all, often some secrete cortisol , causing Cushing's syndrome , aldosterone causing Conn's syndrome , or androgens causing hyperandrogenism . ... Bronchial [ edit ] Bronchial adenomas are adenomas in the bronchi . They may cause carcinoid syndrome , a type of paraneoplastic syndrome . [2] Sebaceous [ edit ] A sebaceous adenoma is a cutaneous condition characterized by a slow-growing tumour usually presenting as a pink, flesh-coloured, or yellow papule or nodule.KRAS, BCL2, CTNNB1, APC, PRL, TSHR, KCNJ5, AIP, TP53, IGF1, MUC2, AMACR, CACNA1D, VHL, ATP1A1, SELENOP, ATP2A3, ALOX5, SLC19A1, TXNRD1, CYP1B1, TRPM7, BCL2L1, ATP2B3, TCN2, MTRR, MIR425, MIR497, SUZ12, GJB1, MIR345, NF1, ABCG2, MIR144, GJA1, PTMA, MIB1, SSTR2, PRKACA, MSH2, EGFR, COX2, MTHFR, CDKN2A, POU1F1, BRAF, SSTR5, CYP11B2, MTCO2P12, CCND1, SST, TRIM21, VEGFA, ESR1, MUTYH, SFRP2, IGF2, SMAD4, POMC, MIR21, CEACAM5, CD44, MRC1, BRD2, GNAS, MC2R, CDC73, LGR5, PTGS2, SLC20A1, PTH, GH1, MEN1, MGMT, H3P10, MLH1, HRAS, MMP7, MKI67, CYP11B1, CALR, RET, HNF1A, PPARG, VDR, FAP, NAT2, TGFB1, PCNA, PAX8, CRP, MSH6, REN, SEPTIN9, TRH, GNRHR, PIK3CA, SFRP1, CRH, EGF, NR0B1, HPGD, HMGA2, ERBB2, NRAS, EPHB2, GHRH, NR3C1, LEP, PTCH1, CDKN1A, MMP1, VIM, MMP9, LGALS3, PRKAR1A, FGF2, MUC1, IL6, CDKN2B, SLC2A1, CASR, KLF4, MUC5AC, HIF1A, IFI27, SLC26A3, ODC1, LEPR, TICAM2, PDE11A, GAPDH, DCC, PSMD9, PLAG1, DCTN6, EPHX1, TMED7, ZNRD2, CYP17A1, CXCL8, MYC, OGG1, ETS1, IL10, MAPK1, TMED7-TICAM2, CDX2, TPO, H3P23, AKR1B1, BAG1, TFF1, GHRHR, ATM, SLC5A5, NQO1, GATA6, MTOR, SLC5A8, PMS2, MCM2, THBS1, MIR503, FOLR1, DCLK1, RUNX3, REG4, SIRT1, WIF1, CEACAM1, USP8, ENPEP, BCL2L11, STK11, NME1, SSTR3, MIR34A, CXCL12, SSTR1, AKT1, MIR143, HSD11B2, PDCD4, TP73, HDAC2, KRT20, KIT, TRHR, CCDC6, BAX, ARHGAP24, FHIT, IGFBP3, IGF2R, GLUL, FDXR, IL17A, IGF1R, UGT1A6, BMI1, LOC110806263, XRCC1, STAT3, F9, RNF43, EZH2, PROM1, GAST, NR5A1, FAS, GLI1, TIMP1, TG, LHCGR, GIP, GHSR, MIR135B, TFF3, GHR, APRT, NKX2-1, TERT, MET, KRT7, MFAP1, APEX1, MIF, KCNH2, TCF7L2, TCF4, INS, COX8A, HTC2, CLOCK, PTGS1, GSTK1, EDN1, SLCO6A1, SLC26A4, GDF15, DRD2, TAS2R38, ABCB1, PROP1, ACE, GCM2, SGK1, CDH13, CDK4, ADIPOQ, ACF, CDKN2C, NOTCH1, RASSF1, SOX2, CASP3, RAF1, ANXA10, MIR137, NEUROD1, TBX19, HSPA4, SMC1A, COX5A, KL, CD274, DKK3, PTPN11, AXIN2, PTPRJ, LIF, SCO2, FST, PSG2, CIB1, TIMP2, MOK, VEGFB, KCNJ1, SORT1, PTGIS, RETREG1, TTF1, IFNG, GHRL, IL1RN, PTGER4, REG1A, PTEN, SDC2, INHA, VEGFC, INSR, CRISP2, PTHLH, GPA33, RB1, MYB, TGFBR2, PPARD, MSI1, PRKN, SMUG1, SLC33A1, PER3, SLC12A1, ABCC1, SPHK1, MSH3, PRDM5, MT3, MAL, SNAP25, SYP, NTRK1, NPM1, SULT1A1, NFE2L2, SOX9, MUC6, SPART, GADD45G, SH3BP4, LILRB1, PDR, ENC1, SLC9A3R2, NOX1, ACAD8, SPN, SFRP4, SHH, PITX1, GREM1, PIK3CG, PIK3CD, PIK3CB, SKP2, PTTG1, PER1, DLK1, HNF1B, MME, PECAM1, SULT2A1, NAT1, CPA1, KLK3, B2M, CLU, SLC26A2, MUC17, CEACAM3, FFAR2, FHL2, CGA, GPT, FGF13, CASP8, CXCL1, NDRG4, MIR126, CD24, PRSS55, EPHB3, CDKN1C, MIR1290, AR, CLDN4, BAAT, TYMP, ELAVL1, GATA4, MIR375, PPP1R2C, CEACAM7, CEACAM4, G6PC, XRCC6, BMP4, GATA2, LRG1, BLM, MIR145, BUB1, BUB1B, SLC38A1, MIR150, EDNRB, EDNRA, MIR148A, CHRM3, GPC3, SPZ1, UCN3, CYP19A1, JAG1, CSE1L, NDRG2, CYP1A1, CDK2, MIR182, HGF, CEMIP, ALB, CDH3, AGTR1, SLC12A9, AFP, GSTM1, CD34, CXADR, MIR214, ADH1C, MIR210, HES1, ERBB3, ERCC2, CTSE, HSD11B1, IMP3, ALCAM, CYP1A2, ALDH1A1, PGR-AS1, THADA, CCK, CLDN7, CPOX, CCKBR, MIR29A, CDKN1B, LINC02210-CRHR1, CYP2C9, APBA1, CRHR1, ALOX15, HAMP, IL33, ALOX12, FHL5, NRXN3, SLC9A3R1, MIR15B, LONP1, MIR155, MIR18A, CHST3, MED7, MRGBP, MIR139, ATG5, ZNF582-AS1, DNM1L, MIR106A, RAD50, C17orf97, LIN28B, CCL4L1, PDZK1IP1, PDCD6IP, CHST4, MACC1, ARMH1, TFAP2E, TRIM13, ENPP7, GJC1, MIR10A, NPEPPS, MIR184, BAG4, CCL4L2, BCAR1, TOX, BMS1, SETDB1, DLEC1, KCNE2, MVP, SLC23A2, FGF19, MED12, MIR130B, NR1I3, MIR183, CLDN2, MIR186, MFT2, CCAT1, FZD6, LINC01672, FZD7, RASAL1, GCM1, MIR1207, PDE8B, TP63, TRIP10, DYNLL1, GAEC1, IRS2, BECN1, MIR760, MIR601, ABCC3, TNFSF10, FZD1, CAHM, TMX2-CTNND1, COMMD3-BMI1, PCGF2, H3P28, ZNF217, LEPQTL1, MALL, CXCR4, H3P9, RN7SL263P, FZD5, SCG2, AIMP2, GHS, TFPI2, TPTEP2-CSNK1E, C5orf66-AS1, FOSL1, MIR4506, CXADRP1, SNAP23, UCA1, MIR371A, CLDN6, PIM3, RABEPK, CLDN1, MIR99A, MIR320A, USP10, MIR31, MIR30E, HGS, ARHGEF2, MIR29C, MIR27B, MAGI1, MIR27A, MIR23B, MIR222, MIR367, MIR372, NORAD, MIR424, CRNDE, TNFRSF11A, MIR483, TNFRSF10A, NRP1, HDAC3, MIR517C, MIR511, MIR491, FUBP1, MIR452, CACNA1H, CACNA1G, MIR451A, MBD4, MBD2, MIR20B, GPHN, HCA1, LILRB2, CHPF, FSD1, LAT, FTO, LAMP3, GGCT, DKK4, WNK1, DKK2, GLS2, HPGDS, RPS6KA6, SGSM3, MARCKSL1, CDH20, SLC26A6, FLVCR1, RGCC, SETD2, DROSHA, BIRC7, FOXD3, NXT1, CKAP2, TRAPPC9, TXNDC5, KCNH6, COL18A1, SPDEF, FBXO11, WLS, BACE2, SNED1, DHDDS, NANOG, LRIG1, CHD5, LIN28A, GALNT12, NAA16, NOC2L, NUPR1, MUL1, SCG3, PYCARD, HCAR2, HSD17B7, IL23A, CRACD, GDE1, NBAS, MPC1, NLK, SHC3, AKR1B10, ACKR3, CHPT1, PMEPA1, GKN1, RAB20, ING3, MEG3, UGT1A1, FBXW7, SYTL2, ESRP1, INTS2, SF1, GORASP1, TSHZ3, SOX17, TNMD, RMC1, TSPYL2, PSAT1, STOML2, NEUROG2, KLK14, IL22, ARHGEF4, IL21, FOXP3, DERL2, CREBZF, TP53INP2, LINC00328, MUC3B, ERGIC2, TRAPPC4, HEY2, FSD1L, IMMP2L, IGF2BP2, TCFL5, NES, TXLNA, GRASP, CBLL2, LRATD1, IL23R, PLK2, RSS, GATA5, PPP1R13L, CD3EAP, ADHFE1, NOXO1, SLC26A1, C1QL1, UTS2, SUB1, EBNA1BP2, SPATA13, NPRL2, CBX7, MAPK15, LANCL1, DLC1, IFITM3, YAP1, PRMT5, RSPO1, GPNMB, LAMA1, CIB2, BCL9L, AGR2, OLFM4, H19, MRPL28, TMEM70, TINCR, PCSK9, SLCO1B1, POSTN, SPPL3, KLK11, UBE2C, WDHD1, TBC1D9, PMPCA, ARC, NAV3, SCIN, NKD1, RERG, TBRG1, SATB2, USP22, RIOX2, CREB3L3, SYNM, MCHR2, SYNE1, HHIPL1, DICER1, USP44, SEC11A, LRCH1, NCOA6, SPEN, TEX30, STRAP, SLC26A7, SAT2, CGB8, CHEK2, CGB5, AKAP10, PNKP, DTD1, ACIN1, GPR182, MGLL, CABLES1, CILK1, ZHX2, DIS3, KCNH7, ATF6, ZFP36, PTPRC, YWHAZ, ACSL4, EFEMP1, FGF3, FGF4, FGFR4, VEGFD, FOXM1, FLT4, FMO3, FN1, FOLH1, FOS, FSHB, FUT4, FUT8, FYN, GABPA, GCG, GDF1, GFRA2, GH2, GIPR, GCLC, GCLM, FBN2, FABP6, DHCR24, FABP3, DMBT1, DNMT3A, DNMT3B, DVL2, E2F4, LPAR1, EEF1G, EGR3, EIF2S1, EPHA2, EIF4EBP1, ELANE, ELK3, ENO2, EPHB1, EPHB4, EPHB6, EPS8, EREG, ERV3-1, ESD, F2R, F3, GLP1R, GLS, GNB3, MCHR1, HP, HPT, HSD3B1, HSD17B1, HSPA5, HSP90AA1, HTN3, HTR4, TNC, IFN1@, IFNA1, IFNA2, IFNA13, IFNA17, IGFBP1, IGFBP2, IGFBP7, IGSF1, IHH, IL1B, IL2, IL6ST, IL9, HOXA9, HMOX1, HMGA1, GUCA2A, GPX1, GPX2, GRP, GSK3B, GSM1, GSN, GSTA1, GSTA4, GSTP1, GSTT1, GUK1, HMBS, GUSB, H2AZ1, HCRT, HCRTR1, HCRTR2, HFE, HGD, HIC1, HLA-B, HLA-DPB1, DLD, DES, INHBC, ZFHX3, ATR, AVP, BACH1, BAGE, BAK1, BCL2A1, BDKRB1, BDNF, BGLAP, BID, FOXL2, BRCA1, BSG, KLF9, KLF5, BTK, TSPO, C3, MPPED2, CA1, CA8, CA9, CALCA, ATP5F1B, ASCL2, DEFA5, ASCL1, ACACA, ADCY3, ADH1B, ADORA2B, PARP1, AGER, ALAS1, ALDH2, ALOX5AP, ANXA3, ANXA6, APBA2, BIRC5, APOB, APOBEC1, APOD, APOE, FASLG, AREG, RND3, ARHGDIB, ARR3, ARSA, CASP10, CAV1, KRIT1, CCND3, CREB1, CRHR2, CSF2, CSNK1D, CSNK1E, VCAN, CTBP1, CTBP2, CTNND1, CTSB, CTSZ, CYB5A, CYLD, CYP2A6, CYP2D6, CYP2E1, CYP3A5, CYP11A1, CYP21A2, CYP24A1, CYP26A1, DEFA1, DEFA3, CRABP1, CR1, MAP3K8, CDH17, CCNE1, MS4A1, CD80, CD86, CD36, SCARB1, CD74, CDK1, CDC25A, CDH1, CDKN3, COL11A1, CDO1, CGB3, CHGA, CHI3L1, CHUK, CIRBP, CNTF, COL1A2, COL2A1, COL4A6, INHBB, INSL3, YY1, RIT2, RNH1, RNU1-4, RRAS, RXRA, S100A4, S100A11, SAT1, SCN7A, SCTR, CCL2, CCL4, CCL5, CCL20, CXCL5, SDHC, SDHD, SHMT1, SKI, SKIL, SLC2A3, SLC6A2, SLC9A2, SLC9A3, RNASE3, RELA, PROS1, RBP4, KLK7, KLK6, PSG9, PSMC4, PSMD7, PSMD10, PTBP1, PTGDR, PTGER2, PTK2, PTPRF, PTPRG, PTPRM, PTX3, PVALB, PVR, RAD51, RAP1A, RAP1B, RAP1GAP, RARB, PLAAT4, RBL1, HLTF, SMS, FSCN1, SORD, TGM2, THBS2, THBS4, THRA, TIE1, TIMP3, TLE4, TLR4, TNF, TPD52, TPM3, TSC2, TWIST1, TYMS, UBE2E2, UCN, SCGB1A1, WNT2, WNT3, WNT5A, XPA, XPC, XRCC5, TGM1, TGFBR1, TGFA, TAC1, SP1, SPG7, SPINK1, SPP1, SRPK1, AURKA, STX1A, ABCC8, VAMP1, SYT1, TACR1, TFRC, TARBP2, TARBP2P1, TBX1, TBP, TCF7, TDGF1, PRDX2, TF, NR2F1, TFPI, PROX1, PRLR, ITGA4, EPCAM, MAS1, MCC, MCL1, MCM7, MDK, MDM2, MDM4, RAB8A, MGAT5, MICE, MMP2, MMP3, MMP14, MPG, MPO, MPZ, MRE11, CITED1, MST1R, MSX1, MTAP, COX1, NUDT1, SMAD9, LYZ, MAP2K1, LUM, ITGAV, ITGB2, EIF6, JAG2, CD82, KCNH1, KCNK3, KDR, KPNA2, KRT15, KRT17, KRT19, LAMA3, LAMP1, RPSA, LCN2, LECT2, LGALS4, LIFR, LIG4, LMAN1, LRP6, LSAMP, MTR, MUC3A, MUC4, MYH11, PCP4, PCSK1, PDE4B, PDE4C, PDGFRB, PGC, PGR, SERPINB5, SERPINE2, PKHD1, PLAU, PLEC, PLK1, PMP22, POLE, POR, PPP2R1B, PRKACB, PRKAR2B, PRKCA, PRKCB, PRKCZ, MAPK3, PCDHGC3, PAX2, PAK1, NFKB1, MYOD1, NAGLU, CEACAM6, RPL10A, NEDD9, NEFM, NELL1, NEUROG1, NF2, NFIB, NOTCH2, SERPINE1, NOTCH3, NRCAM, NTHL1, ROR2, NTS, NTSR1, NR4A2, OGN, OPRD1, OSM, H3P29