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Lymphangioleiomyomatosis
Orphanet
Less frequent differential diagnoses include hypersensitivity pneumonitis, light chain-deposition disease, Birt-Hogg-Dubé syndrome and Sjögren syndrome. Genetic counseling Sporadic LAM is not inherited.TSC2, TSC1, VEGFD, HES1, JAG2, MTOR, SLC12A3, TESC, ACTB, RPS6KB1, ESR1, MMP2, REN, VEGFA, EGFR, EGF, SRF, ACE, PTGS2, IGFBP2, IGF1, PLAU, MAPK1, IGF2, CTNNB1, VEGFC, A1BG, TNF, TIMP3, YWHAZ, SPP1, SOX9, SMN2, SMN1, STAT3, HMGA2, AIMP2, CD274, SFTPA1, MIR21, COPD, PLB1, UBASH3B, COL18A1, PDGFC, ING4, POLDIP2, FOSL1, RNF19A, PLAAT3, PDPN, AHSA1, GPNMB, GGPS1, GRAP2, SFTPD, PMEL, PLG, SELL, CRK, EPHB2, EDN1, DES, CYP19A1, CTSK, CTLA4, MAPK14, CPT1A, CXCL5, CD44, DDR1, BSG, ANXA6, ALDH1A1, AGT, PARP1, GC, GJA1, IFNA1, IFNA13, CCL2, RPS6, PRL, PLA2G1B, PDCD1, SERPINE1, TNFRSF11B, DDR2, MMP14, MMP9, MMP7, MMP1, LMNA, LGALS3, IFNB1, SFTPA2
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Unc80 Deficiency
Gene_reviews
For most individuals the UNC80 deficiency syndrome is not progressive. Individuals have slow acquisition of skills and do not have a loss of skills suggestive of neurodegeneration. ... For most individuals the UNC80 deficiency syndrome is not progressive. Individuals have slow acquisition of skills and do not have the loss of skills suggestive of neurodegeneration. ... Disorders to Consider in the Differential Diagnosis of UNC80 Deficiency View in own window Disorder 1 Gene / Genetic Mechanism Distinguishing Clinical Features Hypotonia, infantile, with psychomotor retardation and characteristic facies 1 (OMIM 615419) NALCN Distinctive facial features incl prominent forehead, short nose, wide mouth, micrognathia, & large, low-set ears; neuroaxonal dystrophy; optic atrophy Hypotonia, infantile, with psychomotor retardation and characteristic facies 3 (OMIM 616900) TBCK Distinctive facial features incl coarse face, bitemporal narrowing, highly arched eyebrows, deeply set eyes, high nasal bridge w/anteverted nares, macroglossia, gingival hyperplasia, & exaggerated cupid's bow; abnormal brain imaging; optic atrophy Phelan-McDermid syndrome Terminal or interstitial deletion of chromosome 22q13.3 Normal or accelerated growth, dolichocephaly, ptosis, epicanthal folds, large or prominent ears, pointed chin, fleshy hands, dysplastic toenails, tendency to overheat Ring chromosome 22 Mild prenatal growth deficiency; mild dysmorphic features incl hypertelorism, epicanthal folds, depressed nasal bridge, & micrognathia; genitourinary anomalies; coloboma of the iris, choroid, &/or optic nerve; microphthalmia; cleft palate; congenital heart malformations; hernias; internal & external ear anomalies Prader-Willi syndrome Abnormal parent-specific imprinting w/in PWCR Polyphagia & obesity, thin vermilion of upper lip w/down-turned corners of the mouth, genitourinary anomalies, acquisition of speech & mobility Angelman syndrome Deficient expression or function of the maternally inherited UBE3A allele Bursts of laughter, macrostomia, tongue protrusion, prognathism, widely spaced teeth, mild cortical atrophy Glass syndrome (OMIM 612313) SATB2 Cleft palate, arachnodactyly, joint laxity, ectodermal anomalies Rett syndrome MECP2 Postnatal microcephaly, seizures, poor growth, esotropia, scoliosis, repetitive behaviors PWCR = Prader-Willi critical region 1.
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Intrauterine Growth Restriction
Wikipedia
Specific causes include: [ citation needed ] Chronic high blood pressure Severe malnutrition Genetic mutations , Ehlers–Danlos syndrome Symmetrical [ edit ] Symmetrical IUGR is commonly known as global growth restriction , and indicates that the fetus has developed slowly throughout the duration of the pregnancy and was thus affected from a very early stage. ... Common causes include: [ citation needed ] Early intrauterine infections, such as cytomegalovirus , rubella or toxoplasmosis Chromosomal abnormalities Anemia Maternal substance use (prenatal alcohol use can result in Fetal alcohol syndrome ) Causes [ edit ] Maternal [ edit ] Pre-pregnancy weight and nutritional status Poor weight gain during pregnancy Malnutrition Anemia Alcohol and/or drug use Maternal smoking Recent pregnancy Pre-gestational diabetes Gestational diabetes Pulmonary disease Cardiovascular disease Kidney disease Hypertension Celiac disease increases the risk of intrauterine growth restriction by an odds ratio of approximately 2.48 [9] Blood clotting disorder/disease (e.g., Factor V Leiden ) Uteroplacental [ edit ] Preeclampsia Multiple gestation Uterine malformations Placental insufficiency Fetal [ edit ] Chromosomal abnormalities Vertically transmitted infections Erythroblastosis fetalis Congenital abnormalities Pathophysiology [ edit ] If the cause of IUGR is extrinsic to the fetus (maternal or uteroplacental), transfer of oxygen and nutrients to the fetus is decreased. ... External links [ edit ] Classification D ICD - 10 : P05.9 ICD - 9-CM : 764.9 MeSH : D005317 DiseasesDB : 6895 External resources MedlinePlus : 001500 eMedicine : article/261226 Patient UK : Intrauterine growth restriction v t e Conditions originating in the perinatal period / fetal disease Maternal factors complicating pregnancy, labour or delivery placenta Placenta praevia Placental insufficiency Twin-to-twin transfusion syndrome chorion / amnion Chorioamnionitis umbilical cord Umbilical cord prolapse Nuchal cord Single umbilical artery presentation Breech birth Asynclitism Shoulder presentation Growth Small for gestational age / Large for gestational age Preterm birth / Postterm pregnancy Intrauterine growth restriction Birth trauma scalp Cephalohematoma Chignon Caput succedaneum Subgaleal hemorrhage Brachial plexus injury Erb's palsy Klumpke paralysis Affected systems Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome Pleural disease Pneumothorax Pneumomediastinum Wilson–Mikity syndrome Bronchopulmonary dysplasia Cardiovascular Pneumopericardium Persistent fetal circulation Bleeding and hematologic disease Vitamin K deficiency bleeding HDN ABO Anti-Kell Rh c Rh D Rh E Hydrops fetalis Hyperbilirubinemia Kernicterus Neonatal jaundice Velamentous cord insertion Intraventricular hemorrhage Germinal matrix hemorrhage Anemia of prematurity Gastrointestinal Ileus Necrotizing enterocolitis Meconium peritonitis Integument and thermoregulation Erythema toxicum Sclerema neonatorum Nervous system Perinatal asphyxia Periventricular leukomalacia Musculoskeletal Gray baby syndrome muscle tone Congenital hypertonia Congenital hypotonia Infections Vertically transmitted infection Neonatal infection rubella herpes simplex mycoplasma hominis ureaplasma urealyticum Omphalitis Neonatal sepsis Group B streptococcal infection Neonatal conjunctivitis Other Miscarriage Perinatal mortality Stillbirth Infant mortality Neonatal withdrawalACADVL, IL1RAPL1, STAMBP, CORIN, TBR1, SIX2, CPLX1, PNPLA6, MID2, PUF60, TRAIP, CNKSR2, IQSEC2, SYNE1, OBSL1, FTSJ1, MTO1, POC1A, EMG1, COQ7, ACTB, PHOX2B, NSD2, ZNF711, ZNF41, USP9X, FZD4, TP63, MBTPS1, RECQL4, HUWE1, CRIPT, ARHGEF6, TTC37, CEP57, FRMPD4, CUL7, MED12, SIN3A, AUTS2, FBXL4, VPS13B, PPP1R15B, WDR73, CREB3L1, CCNQ, RAB39B, DNAJC21, PTCHD1, ARX, MRPS16, UBR1, FLCN, TAPT1, STOX1, PTF1A, H19, ZNF81, SLC9A7, CCDC8, ALG13, ALG12, PAM16, GMNN, SBDS, FGFRL1, NSUN2, TMEM70, PPP2R3C, TRMT1, NGLY1, MCTP2, SHROOM4, FAM111A, ZNF335, CXorf56, UPF3B, WHCR, TSHR, TSPAN7, GCK, FANCC, FANCD2, FANCE, ACSL4, FBN1, FLT1, GATA6, GDI1, IGF1, GK, GPC1, GRIN2A, GTF2E2, HADHA, HADHB, HCFC1, FANCA, ERCC6, ERCC2, EIF2S3, AGTR2, ALB, ASCL1, BUB1B, CLCN4, CNTN1, COL1A1, COL1A2, CTBP1, CYB5A, CYB5R3, DLG3, DMD, DNM2, DYRK1A, HSD11B2, IGF2, THRB, SKIV2L, PIK3R1, POR, PTS, NECTIN1, RBBP8, RET, RPS6KA3, SLC12A1, IGHMBP2, SPR, SRP54, ABCC8, SYP, TAF13, TALDO1, TGFB3, PIK3C2A, PDHA1, PAK3, ORC1, INS, INSR, PDX1, IRF6, KCNJ1, KCNJ11, LETM1, LRP5, SMAD4, MECP2, MSX1, MUSK, MYH3, NDP, NPHS1, USP27X
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Etv6 Thrombocytopenia And Predisposition To Leukemia
Gene_reviews
Individuals with ETV6 thrombocytopenia and predisposition to leukemia most often present with a lifelong history of thrombocytopenia, which is usually in the mild to moderate range. No syndromic features or associations are consistently shared across pedigrees. ... Clinical Characteristics Clinical Description Individuals with ETV6 thrombocytopenia and predisposition to leukemia most often present with a lifelong history of thrombocytopenia, which is usually in the mild to moderate range. No syndromic features or associations are consistently shared across pedigrees. ... Some affected individuals have platelet counts as low as 32x10 9 /L, but severe thrombocytopenia (<20 x 10 9 /L) is rarely seen without concurrent myelodysplastic syndrome. Platelet size is usually normal by automated method (mean platelet volume) or microscopic analysis, although some affected individuals exhibit increased platelet volume. ... Other reported malignancies: Other forms of acute lymphoblastic leukemia Myelodysplastic syndrome (MDS) Acute myeloid leukemia (AML) Mixed phenotype acute leukemia Diffuse large B-cell lymphoma Polycythemia vera Children with ETV6 thrombocytopenia and predisposition to leukemia may be more likely to have hyperdiploid leukemia and be older at the time of diagnosis of leukemia than sporadic cases of leukemia [Moriyama et al 2015]. ... Management Expert and consensus clinical guidelines for the management of inherited thrombocytopenia and leukemia predisposition syndromes, including those with germline ETV6 pathogenic variants, have been proposed [Porter et al 2017, Dupuis & Gachet 2018].
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Adrenal Hypoplasia, Congenital
Omim
Transient precocious sexual development in infancy or early childhood can be a prominent feature of AHC (Landau et al., 2010). A contiguous gene syndrome involving a combination of congenital adrenal hypoplasia, glycerol kinase deficiency (307030), and Duchenne muscular dystrophy (DMD; 310200) is caused by deletion of multiple genes on chromosome Xp21 (see 300679). ... Although no statement was made concerning the sense of smell, the gonadotropin deficiency may have represented Kallmann syndrome (308700). Jones et al. (1995) reported the case of a Hispanic boy with congenital adrenal hypoplasia who had coal-black hyperpigmentation at birth. ... Salvi et al. (2002) noted that heterogeneity both in age at diagnosis and in severity of the adrenal syndrome is a well-recognized feature of AHC, and that variability in the HHG syndrome that classically accompanies AHC has also been reported. ... Again, Addison disease in young males should prompt consideration of ALD as the underlying abnormality. The achalasia-Addisonian syndrome (231550), which appears to be autosomal recessive, is another example of combined adrenal and neurologic (autonomic) involvement. ... The suggestion was based on the finding of an interstitial Xp deletion with breakpoints at p11.2 and p21 in the phenotypically normal mother of a male infant who died at 36 hrs of cytomegalic adrenal hypoplasia with glyceroluria (indicating glycerol kinase deficiency) and deficiency of ornithine carbamoyltransferase (OTC; 300461) in the liver (see Xp21 deletion syndrome, 300679). Yates et al. (1987) found a deletion of Xp21 causing congenital adrenal hypoplasia without glycerol kinase deficiency.NR0B1, ATP1A3, GK, IFNL3, NR5A1, ANOS1, DMD, GPT, SLC2A1, ATP1A2, CACNA1A, SERPINA4, POMC, ESRRB, IFNG, SLC1A3, PCSK1, PMP22, PROP1, STAR, NHS, NR2F2, NR0B2, SOCS3, IL1RAPL1, USP18, ACD, OTC, LEP, MPZ, MC2R, MAGEB1, AMH, ALDH3A2, IL1RAP, ICAM1, HTC2, AKR1B1, CBLIF, CYP11B1, CYP11A1, CTSB, CHAT, CD63, CXCL10
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Visceral Myopathy
Omim
Functional gastrointestinal obstruction also occurs in association with other abnormalities, such as 'prune belly' syndrome (100100) and Barrett esophagus (Mungan syndrome; 611376). ... Marfanoid habitus was noted, which raised a question of the mucosal neuroma syndrome (162300). However, microscopic studies showed normal ganglia and presumably no evidence of neuroma. ... Berdon et al. (1976) first described what they called the 'megacystis-microcolon-intestinal hypoperistalsis syndrome' (MMIH) in 5 female infants, 2 of whom were sisters. ... Her mother suffered from chronic constipation, and family history also included a maternal half brother with enlarged urinary bladder by ultrasound, who died at 4 months of age from sudden infant death syndrome. The third patient presented at birth with vomiting, constipation, abdominal distention, pain, and failure to thrive. ... Cytogenetics Chamyan et al. (2001) reported megacystis-microcolon-intestinal hypoperistalsis syndrome in a fetus with trisomy 18. No ganglion cells were present in the colon or bladder.
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Vascular Anomaly
Wikipedia
Vascular anomalies can also be a part of a syndrome . The estimated prevalence of vascular anomalies is 4.5%. [2] Vascular anomalies can occur throughout the whole body, but in 60% of patients they are localized in the head and neck region. [3] Vascular anomalies can present in various ways, when situated deep below the skin, they appear blue, and are often called cavernous . ... This is called the Kasabach–Merritt syndrome , which is caused by trapping of platelets and other clotting factors within the tumor. ... Capillary malformations constitute 11% of the vascular malformations. [2] Syndromes associated with capillary malformations are: Sturge-Weber syndrome and Klippel-Trenaunay syndrome . [14] Capillary malformations can be treated with IPL -(Intensed-pulsed-light)-therapy or surgical resection . [3] Venous malformation is a bluish lesion compressible on palpation; the masses enlarge with physical activity or if in a dependent position. ... CLVM is associated with Klippel-Trenaunay syndrome AVM-LM : Arteriovenous malformation- lymphatic malformation CM-AVM : capillary malformation- arteriovenous malformation [14] Terminology [ edit ] Correct term Incorrect terminology commonly used to describe vascular anomalies Hemangioma Strawberry Hemangioma Capillary Hemangioma Cavernous Hemangioma Kaposiform hemangioendothelioma (Capillary) Hemangioma Pyogenic granuloma Hemangioma Capillary Malformation Port-wine stain Capillary Hemangioma Lymphatic Malformation Lymphangioma Cystic hygroma Venous Malformation Cavernous Hemangioma Arteriovenous malformation Arteriovenous Hemangioma [2] References [ edit ] ^ Steiner, JE; Drolet, BA (September 2017). ... "Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome: a new indication for propranolol treatment".
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Brainstem Death
Wikipedia
Clinical syndrome Brainstem death is a clinical syndrome defined by the absence of reflexes with pathways through the brainstem —the "stalk" of the brain, which connects the spinal cord to the mid-brain , cerebellum and cerebral hemispheres —in a deeply comatose, ventilator -dependent patient. ... In 1995, after a review by a Working Group of the Royal College of Physicians of London , the Conference of Medical Royal Colleges [2] formally adopted the "more correct" term for the syndrome, "brainstem death"—championed by Pallis in a set of 1982 articles in the British Medical Journal [8] —and advanced a new definition of human death as the basis for equating this syndrome with the death of the person. ... There should, perhaps, also be a caveat about possible arousal mechanisms involving the first and second cranial nerves (serving sight and smell) which are not tested when diagnosing brainstem death but which were described in cats in 1935 and 1938. [20] In humans, light flashes have been observed to disturb the sleep-like EEG activity persisting after the loss of all brainstem reflexes and of spontaneous respiration. [26] There is also concern about the permanence of consciousness loss, based on studies in cats, dogs and monkeys which recovered consciousness days or weeks after being rendered comatose by brainstem ablation and on human studies of brainstem stroke syndrome raising thoughts about the "plasticity" of the nervous system. [23] Other theories of consciousness place more stress on the thalamocortical system. [27] Perhaps the most objective statement to be made is that consciousness is not currently understood. ... Anaesthesia 1993;48:1034–38 External links [ edit ] Great Ormond Street Hospital for Children v t e Death In medicine Cell death Necrosis Avascular necrosis Coagulative necrosis Liquefactive necrosis Gangrenous necrosis Caseous necrosis Fat necrosis Fibrinoid necrosis Temporal lobe necrosis Programmed cell death AICD Anoikis Apoptosis Autophagy Intrinsic apoptosis Necroptosis Paraptosis Parthanatos Phenoptosis Pseudoapoptosis Pyroptosis Autolysis Autoschizis Eschar Immunogenic cell death Ischemic cell death Pyknosis Karyorrhexis Karyolysis Mitotic catastrophe Suicide gene Abortion Accidental death Autopsy Brain death Brainstem death Clinical death DOA Death by natural causes Death rattle Dysthanasia End-of-life care Euthanasia Lazarus sign Lazarus syndrome Medical definition of death Organ donation Terminal illness Unnatural death Lists Causes of death by rate Expressions related to death Natural disasters People by cause of death Premature obituaries Preventable causes of death Notable deaths by year Unusual deaths Mortality Birthday effect Child mortality Gompertz–Makeham law of mortality Infant mortality Karoshi Maternal death Maternal mortality in fiction Memento mori Micromort Mortality displacement Mortality rate RAMR Mortality salience Perinatal mortality After death Body Stages Pallor mortis Algor mortis Rigor mortis Livor mortis Putrefaction Decomposition Skeletonization Fossilization Preservation Cryopreservation Cryonics Neuropreservation Embalming Maceration Mummification Plastination Prosection Taxidermy Disposal Burial Natural burial Cremation Dismemberment Excarnation Promession Resomation Beating heart cadaver Body donation Cadaveric spasm Coffin birth Death erection Dissection Gibbeting Postmortem caloricity Post-mortem interval Other aspects Afterlife Cemetery Consciousness Customs Crematorium Examination Funeral Grief Intermediate state Internet Mourning Online mourning Obituary Vigil Paranormal Ghosts Near-death experience Near-death studies Necromancy Out-of-body experience Reincarnation research Séance Legal Abortion law Administration Capital punishment Cause of death Civil death Coroner Death-qualified jury Death certificate Declared death in absentia Death row Dying declaration Inquest Legal death Murder Necropolitics Prohibition of death Right to die Suspicious death Trust law Will Fields Forensic pathology Funeral director Mortuary science Necrobiology Post-mortem chemistry Post-mortem photography Taphonomy Biostratinomy Thanatology Other Apparent death Dark tourism Darwin Awards Death and culture Death anniversary Death anxiety Death deity Personification of death Dying-and-rising god Psychopomp Death camp Death drive Death education Death from laughter Death hoax Death knell Death march Death messenger Death notification Death panel Death poem Death pose Death-positive movement Death squad Death threat Death trajectory Dignified death Extinction Fan death Festival of the Dead Fascination with death Hierarchy of death Homicide Last rites Martyr Megadeath Museum of Death Necronym Necrophilia Necrophobia The Order of the Good Death Predation Sacrifice human Suicide Assisted suicide Thanatosensitivity The Goodbye Family Category Outline v t e Disorders of consciousness Unconsciousness Minimally conscious state Persistent vegetative state Obtundation Coma Brain stem death Stupor Sopor Sleep Somnolence Cataplexy Syncope Heat syncope Vasovagal episode Alteration of consciousness Locked-in syndrome
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Osteochondroma
Wikipedia
External links [ edit ] Humpath #2790 (Pathology images) American Academy of Orthopedic Surgeons Classification D ICD - 10 : D16 ICD-O : 9210/0 MeSH : D015831 DiseasesDB : 34033 SNOMED CT : 443093007 External resources eMedicine : article/1256477 v t e Tumours of bone and cartilage Diaphysis Multiple myeloma Epithelia Adamantinoma Primitive neuroectodermal tumor Ewing family Ewing's sarcoma Metaphysis Osteoblast Osteoid osteoma Osteoblastoma Osteoma / osteosarcoma Chondroblast Chondroma / ecchondroma / enchondroma Enchondromatosis Extraskeletal chondroma Chondrosarcoma Mesenchymal chondrosarcoma Myxoid chondrosarcoma Osteochondroma Osteochondromatosis Chondromyxoid fibroma Fibrous Ossifying fibroma Fibrosarcoma Epiphysis Chondroblast Chondroblastoma Myeloid Giant-cell tumor of bone Other Notochord Chordoma v t e Osteochondrodysplasia Osteodysplasia/ / osteodystrophy Diaphysis Camurati–Engelmann disease Metaphysis Metaphyseal dysplasia Jansen's metaphyseal chondrodysplasia Schmid metaphyseal chondrodysplasia Epiphysis Spondyloepiphyseal dysplasia congenita Multiple epiphyseal dysplasia Otospondylomegaepiphyseal dysplasia Osteosclerosis Raine syndrome Osteopoikilosis Osteopetrosis Other/ungrouped FLNB Boomerang dysplasia Opsismodysplasia Polyostotic fibrous dysplasia McCune–Albright syndrome Chondrodysplasia / chondrodystrophy (including dwarfism ) Osteochondroma osteochondromatosis Hereditary multiple exostoses Chondroma / enchondroma enchondromatosis Ollier disease Maffucci syndrome Growth factor receptor FGFR2 : Antley–Bixler syndrome FGFR3 : Achondroplasia Hypochondroplasia Thanatophoric dysplasia COL2A1 collagen disease Achondrogenesis type 2 Hypochondrogenesis SLC26A2 sulfation defect Achondrogenesis type 1B Autosomal recessive multiple epiphyseal dysplasia Atelosteogenesis, type II Diastrophic dysplasia Chondrodysplasia punctata Rhizomelic chondrodysplasia punctata Conradi–Hünermann syndrome Other dwarfism Fibrochondrogenesis Short rib – polydactyly syndrome Majewski's polydactyly syndrome Léri–Weill dyschondrosteosisPTPN11, FGFR3, PRKAR1A, EXT1, TMEM94, GLI3, EXT2, BCL2, HSPG2, PTGS2, PCNA, PTHLH, HPSE, TRIM13, SPON1, NPRL2, NR1I3, DCTN3, PROM1, CHP1, PHB2, KAT6B, DISC1, CD274, THEM4, MIR503, CXADRP1, HDAC4, AKT1, SPP1, SPG7, BGLAP, BMP2, CASR, CLCN5, CXADR, DYNC1H1, FGF9, FN1, GPC3, IHH, KCNH1, COX2, ARR3, RARG, SDC2, MTCO2P12
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Acute Necrotizing Ulcerative Gingivitis
Wikipedia
Younger Other specialties Endodontology Orthodontology Prosthodontology v t e Bacterial diseases due to gram negative non- proteobacteria ( BV4 ) Spirochaete Spirochaetaceae Treponema Treponema pallidum Syphilis / bejel Yaws Treponema carateum ( Pinta ) Treponema denticola Borrelia Borrelia burgdorferi / Borrelia afzelii Lyme disease Erythema migrans Neuroborreliosis Borrelia recurrentis ( Louse borne relapsing fever ) Borrelia hermsii / Borrelia duttoni / Borrelia parkeri ( Tick borne relapsing fever ) Leptospiraceae Leptospira Leptospira interrogans ( Leptospirosis ) Chlamydiaceae Chlamydia Chlamydia psittaci ( Psittacosis ) Chlamydia pneumoniae Chlamydia trachomatis Chlamydia Lymphogranuloma venereum Trachoma Bacteroidetes Bacteroides fragilis Tannerella forsythia Capnocytophaga canimorsus Porphyromonas gingivalis Prevotella intermedia Fusobacteria Fusobacterium necrophorum ( Lemierre's syndrome ) Fusobacterium nucleatum Fusobacterium polymorphum Streptobacillus moniliformis ( Rat-bite fever / Haverhill fever ) v t e Oral and maxillofacial pathology Lips Cheilitis Actinic Angular Plasma cell Cleft lip Congenital lip pit Eclabium Herpes labialis Macrocheilia Microcheilia Nasolabial cyst Sun poisoning Trumpeter's wart Tongue Ankyloglossia Black hairy tongue Caviar tongue Crenated tongue Cunnilingus tongue Fissured tongue Foliate papillitis Glossitis Geographic tongue Median rhomboid glossitis Transient lingual papillitis Glossoptosis Hypoglossia Lingual thyroid Macroglossia Microglossia Rhabdomyoma Palate Bednar's aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Torus palatinus Oral mucosa – Lining of mouth Amalgam tattoo Angina bullosa haemorrhagica Behçet's disease Bohn's nodules Burning mouth syndrome Candidiasis Condyloma acuminatum Darier's disease Epulis fissuratum Erythema multiforme Erythroplakia Fibroma Giant-cell Focal epithelial hyperplasia Fordyce spots Hairy leukoplakia Hand, foot and mouth disease Hereditary benign intraepithelial dyskeratosis Herpangina Herpes zoster Intraoral dental sinus Leukoedema Leukoplakia Lichen planus Linea alba Lupus erythematosus Melanocytic nevus Melanocytic oral lesion Molluscum contagiosum Morsicatio buccarum Oral cancer Benign: Squamous cell papilloma Keratoacanthoma Malignant: Adenosquamous carcinoma Basaloid squamous carcinoma Mucosal melanoma Spindle cell carcinoma Squamous cell carcinoma Verrucous carcinoma Oral florid papillomatosis Oral melanosis Smoker's melanosis Pemphigoid Benign mucous membrane Pemphigus Plasmoacanthoma Stomatitis Aphthous Denture-related Herpetic Smokeless tobacco keratosis Submucous fibrosis Ulceration Riga–Fede disease Verruca vulgaris Verruciform xanthoma White sponge nevus Teeth ( pulp , dentin , enamel ) Amelogenesis imperfecta Ankylosis Anodontia Caries Early childhood caries Concrescence Failure of eruption of teeth Dens evaginatus Talon cusp Dentin dysplasia Dentin hypersensitivity Dentinogenesis imperfecta Dilaceration Discoloration Ectopic enamel Enamel hypocalcification Enamel hypoplasia Turner's hypoplasia Enamel pearl Fluorosis Fusion Gemination Hyperdontia Hypodontia Maxillary lateral incisor agenesis Impaction Wisdom tooth impaction Macrodontia Meth mouth Microdontia Odontogenic tumors Keratocystic odontogenic tumour Odontoma Dens in dente Open contact Premature eruption Neonatal teeth Pulp calcification Pulp stone Pulp canal obliteration Pulp necrosis Pulp polyp Pulpitis Regional odontodysplasia Resorption Shovel-shaped incisors Supernumerary root Taurodontism Trauma Avulsion Cracked tooth syndrome Vertical root fracture Occlusal Tooth loss Edentulism Tooth wear Abrasion Abfraction Acid erosion Attrition Periodontium ( gingiva , periodontal ligament , cementum , alveolus ) – Gums and tooth-supporting structures Cementicle Cementoblastoma Gigantiform Cementoma Eruption cyst Epulis Pyogenic granuloma Congenital epulis Gingival enlargement Gingival cyst of the adult Gingival cyst of the newborn Gingivitis Desquamative Granulomatous Plasma cell Hereditary gingival fibromatosis Hypercementosis Hypocementosis Linear gingival erythema Necrotizing periodontal diseases Acute necrotizing ulcerative gingivitis Pericoronitis Peri-implantitis Periodontal abscess Periodontal trauma Periodontitis Aggressive As a manifestation of systemic disease Chronic Perio-endo lesion Teething Periapical, mandibular and maxillary hard tissues – Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic : periapical Dentigerous Buccal bifurcation Lateral periodontal Globulomaxillary Calcifying odontogenic Glandular odontogenic Non-odontogenic: Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Osteomyelitis Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget's disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis Temporomandibular joints , muscles of mastication and malocclusions – Jaw joints, chewing muscles and bite abnormalities Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overeruption Overjet Prognathia Retrognathia Scissor bite Maxillary hypoplasia Temporomandibular joint dysfunction Salivary glands Benign lymphoepithelial lesion Ectopic salivary gland tissue Frey's syndrome HIV salivary gland disease Necrotizing sialometaplasia Mucocele Ranula Pneumoparotitis Salivary duct stricture Salivary gland aplasia Salivary gland atresia Salivary gland diverticulum Salivary gland fistula Salivary gland hyperplasia Salivary gland hypoplasia Salivary gland neoplasms Benign: Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: Acinic cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Carcinoma ex pleomorphic adenoma Lymphoma Mucoepidermoid carcinoma Sclerosing polycystic adenosis Sialadenitis Parotitis Chronic sclerosing sialadenitis Sialectasis Sialocele Sialodochitis Sialosis Sialolithiasis Sjögren's syndrome Orofacial soft tissues – Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig's angina Macrostomia Melkersson–Rosenthal syndrome Microstomia Noma Oral Crohn's disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans Other Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic disease
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Cracked Nipple
Wikipedia
External links [ edit ] Classification D ICD - 10 : N64.0 , O92.1 ICD - 9-CM : 611.2 External resources MedlinePlus : 000632 v t e Breastfeeding Anatomy, physiology and immunolgy Anti inflammatory agents in breast milk Areola Areolar gland (gland of Montgomery) Breast Breast anatomy Breast crawl Breast milk Breastfeeding and medications Dysphoric milk ejection reflex Frenulum of tongue Galactose Human milk oligosaccharide Hypothalamic–pituitary–prolactin_axis Latching on Lactation suppression Lactiferous duct Lactose Milk Overactive let-down Oxytocin Passive immunity Prolactin Prolactin modulator Colostrum Lactation Nipple Mammary gland Mammary alveoli Mammary lobule Disorders and difficulties Blocked milk duct Breastfeeding difficulties Breast engorgement Low milk supply Cracked nipple Mastitis Milk blister (milk bleb) Nipple vasospasm Neonatal jaundice Breastfeeding infertility Breastfeeding and HIV Prolactinoma Breastfeeding and mental health Culture and support Breastfeeding advocacy Breastfeeding in art Breastfeeding in public Breastfeeding in the United States Breastfeeding organizations Breastfeeding promotion Child's Right to Nurse Act Diana West (lactation consultant) History and culture of breastfeeding Human-animal breastfeeding Human milk bank Human milk banking in North America International Breastfeeding Symbol Jack Newman (doctor) International Breast Milk Project La Leche League Lactation room Lactivism Mothers' rights Pat Shelly Amy Spangler Mary Rose Tully World Breastfeeding Week Roles Doula Midwifery Lactation consultant Lactation counselor List of breastfeeding activists Wet nurse Equipment used with breastfeeding Breast pump Nipple shield Nursing bra Nursing chair Supplemental nursing system Other topics Baby-led weaning Weaning Extended breastfeeding v t e Breast disease Inflammation Mastitis Nonpuerperal mastitis Subareolar abscess Granulomatous mastitis Physiological changes and conditions Benign mammary dysplasia Duct ectasia of breast Chronic cystic mastitis Mammoplasia Gynecomastia Adipomastia (lipomastia, pseudogynecomastia) Breast hypertrophy Breast atrophy Micromastia Amastia Anisomastia Breast engorgement Nipple Nipple discharge Galactorrhea Inverted nipple Cracked nipples Nipple pigmentation Masses Galactocele Breast cyst Breast hematoma Breast lump Pseudoangiomatous stromal hyperplasia Other Pain Tension Ptosis Fat necrosis Amazia v t e Pathology of pregnancy , childbirth and the puerperium Pregnancy Pregnancy with abortive outcome Abortion Ectopic pregnancy Abdominal Cervical Interstitial Ovarian Heterotopic Embryo loss Fetal resorption Molar pregnancy Miscarriage Stillbirth Oedema , proteinuria and hypertensive disorders Gestational hypertension Pre-eclampsia HELLP syndrome Eclampsia Other, predominantly related to pregnancy Digestive system Acute fatty liver of pregnancy Gestational diabetes Hepatitis E Hyperemesis gravidarum Intrahepatic cholestasis of pregnancy Integumentary system / dermatoses of pregnancy Gestational pemphigoid Impetigo herpetiformis Intrahepatic cholestasis of pregnancy Linea nigra Prurigo gestationis Pruritic folliculitis of pregnancy Pruritic urticarial papules and plaques of pregnancy (PUPPP) Striae gravidarum Nervous system Chorea gravidarum Blood Gestational thrombocytopenia Pregnancy-induced hypercoagulability Maternal care related to the fetus and amniotic cavity amniotic fluid Oligohydramnios Polyhydramnios Braxton Hicks contractions chorion / amnion Amniotic band syndrome Chorioamnionitis Chorionic hematoma Monoamniotic twins Premature rupture of membranes Obstetrical bleeding Antepartum placenta Circumvallate placenta Monochorionic twins Placenta accreta Placenta praevia Placental abruption Twin-to-twin transfusion syndrome Labor Amniotic fluid embolism Cephalopelvic disproportion Dystocia Shoulder dystocia Fetal distress Locked twins Nuchal cord Obstetrical bleeding Postpartum Pain management during childbirth placenta Placenta accreta Preterm birth Postmature birth Umbilical cord prolapse Uterine inversion Uterine rupture Vasa praevia Puerperal Breastfeeding difficulties Low milk supply Cracked nipples Breast engorgement Childbirth-related posttraumatic stress disorder Diastasis symphysis pubis Postpartum bleeding Peripartum cardiomyopathy Postpartum depression Postpartum psychosis Postpartum thyroiditis Puerperal fever Puerperal mastitis Other Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy Category v t e Infants and their care Health ( Pediatrics ) Baby food Birth weight Breast pump Breastfeeding Breastfeeding and medications Bottle feeding Colic Immunizations Cradle cap Cross eyed Failure to thrive Immunization Infant and toddler safety Infant bathing Infant food safety Infant formula Infant massage Infant food safety Infant nutrition Infant respiratory distress syndrome Infant sleep training Neo-natal intensive care unit Newborn care and safety Oral rehydration therapy Pedialyte Preterm birth Shaken baby syndrome Soy formula Sudden infant death syndrome Breastfeeding and mental health Development Attachment parenting Baby-led weaning Baby talk Babbling Childbirth Congenital disorder Crawling Infant visual development Diaper rash Gestational age Infant cognitive development Kangaroo care Mother Nursery Rhyme Object permanence Parent Parenting Peekaboo Play Prenatal development Prenatal development table Teething Types of crying Walking Weaning Socialization and Culture Attachment Babysitting Child abuse Child custody Child's rights UN Child rights Circumcision Daycare Foster care Grandparent visitation Infant swimming Milk bank Nanny Wet nurse Infant care and equipment Baby bouncer Baby gate Baby monitor / Hidden camera Baby powder Baby shampoo Baby toy Baby walker Bib Baby swing Baby transport Bassinet Car seat safety Cloth diaper Cradle board Diaper Diaper bag Baby wipes Haberman Feeder High chair Infant bed (American 'crib' and 'cradle', British 'cot') Infant carrier Infant clothing Pacifier Playpen Stroller Supplemental nursing system Swaddling Swim diaper Teether Travel cot Other topics Baby shower Babywearing Child neglect Closed adoption Cry room Infant ear piercing Open adoption Prenatal cocaine exposure Neonatal withdrawal syndrome Parental child abduction Parental responsibility Parenting plan Paternity Paternity fraud
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Hydronephrosis
Wikipedia
Hydronephrosis can be a cause of pyonephrosis , which is a urological emergency. [17] References [ edit ] ^ K, Mergener; Jl, Weinerth; J, Baillie (December 1997). "Dietl's Crisis: A Syndrome of Episodic Abdominal Pain of Urologic Origin That May Present to a Gastroenterologist". ... Oxford: Oxford University Press. v t e Kidney disease Glomerular disease See Template:Glomerular disease Tubules Renal tubular acidosis proximal distal Acute tubular necrosis Genetic Fanconi syndrome Bartter syndrome Gitelman syndrome Liddle's syndrome Interstitium Interstitial nephritis Pyelonephritis Balkan endemic nephropathy Vascular Renal artery stenosis Renal ischemia Hypertensive nephropathy Renovascular hypertension Renal cortical necrosis General syndromes Nephritis Nephrosis Renal failure Acute renal failure Chronic kidney disease Uremia Other Analgesic nephropathy Renal osteodystrophy Nephroptosis Abderhalden–Kaufmann–Lignac syndrome Diabetes insipidus Nephrogenic Renal papilla Renal papillary necrosis Major calyx / pelvis Hydronephrosis Pyonephrosis Reflux nephropathy v t e Medicine Specialties and subspecialties Surgery Cardiac surgery Cardiothoracic surgery Colorectal surgery Eye surgery General surgery Neurosurgery Oral and maxillofacial surgery Orthopedic surgery Hand surgery Otolaryngology ENT Pediatric surgery Plastic surgery Reproductive surgery Surgical oncology Transplant surgery Trauma surgery Urology Andrology Vascular surgery Internal medicine Allergy / Immunology Angiology Cardiology Endocrinology Gastroenterology Hepatology Geriatrics Hematology Hospital medicine Infectious disease Nephrology Oncology Pulmonology Rheumatology Obstetrics and gynaecology Gynaecology Gynecologic oncology Maternal–fetal medicine Obstetrics Reproductive endocrinology and infertility Urogynecology Diagnostic Radiology Interventional radiology Nuclear medicine Pathology Anatomical Clinical pathology Clinical chemistry Cytopathology Medical microbiology Transfusion medicine Other Addiction medicine Adolescent medicine Anesthesiology Dermatology Disaster medicine Diving medicine Emergency medicine Mass gathering medicine Family medicine General practice Hospital medicine Intensive care medicine Medical genetics Narcology Neurology Clinical neurophysiology Occupational medicine Ophthalmology Oral medicine Pain management Palliative care Pediatrics Neonatology Physical medicine and rehabilitation PM&R Preventive medicine Psychiatry Addiction psychiatry Radiation oncology Reproductive medicine Sexual medicine Sleep medicine Sports medicine Transplantation medicine Tropical medicine Travel medicine Venereology Medical education Medical school Bachelor of Medicine, Bachelor of Surgery Bachelor of Medical Sciences Master of Medicine Master of Surgery Doctor of Medicine Doctor of Osteopathic Medicine MD–PhD Related topics Alternative medicine Allied health Dentistry Podiatry Pharmacy Physiotherapy Molecular oncology Nanomedicine Personalized medicine Public health Rural health Therapy Traditional medicine Veterinary medicine Physician Chief physician History of medicine Book Category Commons Wikiproject Portal OutlinePTGS2, IDH2, PTGER1, PTGES, EGR1, IL1B, TBXAS1, GLI3, SIX1, TFAP2A, WNT5A, COG1, RECQL4, PEX16, KIAA0753, PIGL, TBX18, PIGQ, SEMA3E, ZEB2, ACTB, LRIG2, WASHC5, TP63, ARNT2, CRTAP, EBP, SPINK5, B4GAT1, POLR3A, RAB3GAP1, RAB18, PEX11B, LTBP4, KCNAB2, XDH, SMARCE1, SOX4, SOX9, SOX11, SPG7, MAP3K7, ACTG1, TBX15, KDM6A, WFS1, ZIC3, PEX3, KAT6A, KMT2D, MKKS, NRIP1, USP9X, RBM10, NAA10, ARID1A, TRRAP, OFD1, SPART, KAT6B, SMARCB1, C12orf57, SOX17, NXN, PORCN, DYNC2H1, EHMT1, PIGO, PIGY, SHANK3, WDR34, COG7, PGAP3, CHST14, TBC1D20, PIGN, B3GLCT, CCBE1, SIX5, ASXL1, ARID2, UBR1, TAPT1, HYLS1, KANSL1, PIGW, MYMK, RNU4ATAC, STRA6, PRDM16, PIEZO2, HPSE2, RAB3GAP2, SETBP1, PTPN22, PGAP2, CCDC22, GEMIN4, NSDHL, MBTPS2, RAB23, MAGEL2, BNC2, BCOR, NSUN2, NCAPG2, WDR60, CHD7, PIGV, PEX26, PACS1, FMN2, SALL4, TBC1D24, ARID1B, WDR35, IFT80, SMARCC2, TBX1, SMARCA4, LIG4, FANCB, GPC4, FGFR1, FGFR2, FOXF1, FLI1, FLNA, GABRD, GATA3, GATA6, GNB1, GRIA3, HLA-DPA1, HLA-DPB1, HOXD13, IARS1, ITGA6, ITGB4, KCNMA1, EYA1, ERBB3, DVL3, CDC42, ACTG2, APC, ARL3, RERE, ATP7A, ATRX, BRAF, MYRF, CDKN1C, DVL1, CENPF, CHN1, CHRM3, CLCNKB, CPT2, CTLA4, CTNNB1, DHCR7, KRAS, GPC3, KCNMA1-AS1, RAP1A, MAP2K1, PPP3CA, POLE, PRTN3, PLEC, PLD1, PEX19, PEX2, PEX5, PEX14, PEX13, PEX12, MAP2K2, RAD51C, PEX10, PEX6, SHH, SKI, NBN, NFIA, RAP1B, ROR2, MASP1, DPF2, PEX1, AMBP, LCN2, PUJO, HAVCR1, VUR, ALB, CCL2, CISH, TGFB1, BMP4, AHR, EGF, KCNJ1, VNN1, FBN1, SCT, CD68, CASP3, G6PC3, RASSF1, SOCS1, OGA, OSR1, SCN7A, ATP5F1B, SOCS3, ETFB, ABCC6, AQP2, AQP1, SEMA3A, NAGLU, MECP2, NPS, GDF15, C16orf95, GSS, ZCCHC14, TNF, CLMP, NBAS, EPHA7, EPHA4, MS, PLG, PTCH1, DLG1, FOLH1, ACE, CYP1A1, CTSS, HCN3, SERPINE2, VWF, CST3, CRP, VEGFA, GATA2, SLC12A3, UPK1B, TXN, MYH10
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Factor V Leiden
Wikipedia
Factor V Leiden Thrombophilia Explained - Genome.gov External links [ edit ] Classification D ICD - 10 : D68.51 ICD - 9-CM : 289.81 OMIM : 188055 MeSH : C095381 DiseasesDB : 154 v t e Disorders of bleeding and clotting Coagulation · coagulopathy · Bleeding diathesis Clotting By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin G20210A Platelets Sticky platelet syndrome Thrombocytosis Essential thrombocythemia DIC Purpura fulminans Antiphospholipid syndrome Clots Thrombophilia Thrombus Thrombosis Virchow's triad Trousseau sign of malignancy By site Deep vein thrombosis Bancroft's sign Homans sign Lisker's sign Louvel's sign Lowenberg's sign Peabody's sign Pratt's sign Rose's sign Pulmonary embolism Renal vein thrombosis Bleeding By cause Thrombocytopenia Thrombocytopenic purpura : ITP Evans syndrome TM TTP Upshaw–Schulman syndrome Heparin-induced thrombocytopenia May–Hegglin anomaly Platelet function adhesion Bernard–Soulier syndrome aggregation Glanzmann's thrombasthenia platelet storage pool deficiency Hermansky–Pudlak syndrome Gray platelet syndrome Clotting factor Hemophilia A/VIII B/IX C/XI von Willebrand disease Hypoprothrombinemia/II Factor VII deficiency Factor X deficiency Factor XII deficiency Factor XIII deficiency Dysfibrinogenemia Congenital afibrinogenemia Signs and symptoms Bleeding Bruise Hematoma Petechia Purpura Nonthrombocytopenic purpura By site head Epistaxis Hemoptysis Intracranial hemorrhage Hyphema Subconjunctival hemorrhage torso Hemothorax Hemopericardium Pulmonary hematoma abdomen Gastrointestinal bleeding Hemobilia Hemoperitoneum Hematocele Hematosalpinx joint HemarthrosisACE, F2, PC, F5, COX8A, SERPINE1, MTHFR, PROC, SERPINC1, PROS1, F3, LPA, APC, THBD, APOE, ITGB3, TFPI, PLA2G2A, PLA2G6, F10, PLA2G1B, APOH, VWF, FGB, C20orf181, HFE, JAK2, VKORC1, CPB2, F8, ANXA5, PLG, PPP1R3C, POR, PRCP, PRH1, PGR-AS1, PRH2, ZNF469, HPSE, SAFB, PPP1R3B, PTPRC, ADAMTS13, SELE, SSAV1, PGPEP1, UGT1A1, VTN, ZFP36, MRPL37, SH3BP4, MMRN1, ABO, LPL, SERPINA5, F13A1, ATD, BCS1L, BMP1, TSPO, CASP3, CBS, CDSN, CHRM3, CPD, CYP2C9, DHFR, DPYD, F9, FN1, PRKN, GP1BA, GPI, HABP2, SERPIND1, HP, IL6, ITGA2, ITPR1, AGT, ATXN3, NOS3, SLC22A18, SERPINB2, CBSL
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Allergic Contact Dermatitis
Wikipedia
External links [ edit ] Classification D ICD - 10 : L23 ICD - 9-CM : 691.8 MeSH : D017449 DiseasesDB : 29435 v t e Dermatitis and eczema Atopic dermatitis Besnier's prurigo Seborrheic dermatitis Pityriasis simplex capillitii Cradle cap Contact dermatitis ( allergic , irritant ) plants: Urushiol-induced contact dermatitis African blackwood dermatitis Tulip fingers other: Abietic acid dermatitis Diaper rash Airbag dermatitis Baboon syndrome Contact stomatitis Protein contact dermatitis Eczema Autoimmune estrogen dermatitis Autoimmune progesterone dermatitis Breast eczema Ear eczema Eyelid dermatitis Topical steroid addiction Hand eczema Chronic vesiculobullous hand eczema Hyperkeratotic hand dermatitis Autosensitization dermatitis / Id reaction Candidid Dermatophytid Molluscum dermatitis Circumostomy eczema Dyshidrosis Juvenile plantar dermatosis Nummular eczema Nutritional deficiency eczema Sulzberger–Garbe syndrome Xerotic eczema Pruritus / Itch / Prurigo Lichen simplex chronicus / Prurigo nodularis by location: Pruritus ani Pruritus scroti Pruritus vulvae Scalp pruritus Drug-induced pruritus Hydroxyethyl starch-induced pruritus Senile pruritus Aquagenic pruritus Aquadynia Adult blaschkitis due to liver disease Biliary pruritus Cholestatic pruritus Prion pruritus Prurigo pigmentosa Prurigo simplex Puncta pruritica Uremic pruritus Other substances taken internally: Bromoderma Fixed drug reaction Nummular dermatitis Pityriasis alba Papuloerythroderma of Ofuji v t e Hypersensitivity and autoimmune diseases Type I / allergy / atopy ( IgE ) Foreign Atopic eczema Allergic urticaria Allergic rhinitis (Hay fever) Allergic asthma Anaphylaxis Food allergy common allergies include: Milk Egg Peanut Tree nut Seafood Soy Wheat Penicillin allergy Autoimmune Eosinophilic esophagitis Type II / ADCC IgM IgG Foreign Hemolytic disease of the newborn Autoimmune Cytotoxic Autoimmune hemolytic anemia Immune thrombocytopenic purpura Bullous pemphigoid Pemphigus vulgaris Rheumatic fever Goodpasture syndrome Guillain–Barré syndrome " Type V "/ receptor Graves' disease Myasthenia gravis Pernicious anemia Type III ( Immune complex ) Foreign Henoch–Schönlein purpura Hypersensitivity vasculitis Reactive arthritis Farmer's lung Post-streptococcal glomerulonephritis Serum sickness Arthus reaction Autoimmune Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis Type IV / cell-mediated ( T cells ) Foreign Allergic contact dermatitis Mantoux test Autoimmune Diabetes mellitus type 1 Hashimoto's thyroiditis Multiple sclerosis Coeliac disease Giant-cell arteritis Postorgasmic illness syndrome Reactive arthritis GVHD Transfusion-associated graft versus host disease Unknown/ multiple Foreign Hypersensitivity pneumonitis Allergic bronchopulmonary aspergillosis Transplant rejection Latex allergy (I+IV) Autoimmune Sjögren syndrome Autoimmune hepatitis Autoimmune polyendocrine syndrome APS1 APS2 Autoimmune adrenalitis Systemic autoimmune diseaseTNF, IL10, IFNG, SPP1, PLAT, IL1A, IL18, CCL19, HSD11B1, IPCEF1, SELE, IL2, IL2RA, IL4, IL5, QPCT, SLC2A3, PRDX4, ST6GAL1, CCR2, ITGAM, TLR7, MXD1, ABCA6, MEOX1, PHLDA1, MRC1, NFE2L2, NINJ1, NUMA1, CNTN3, PIM1, RAB32, FGL2, RGS1, SAT1, IFI30, STAC, CXCL2, KMO, IGSF6, CISH, CTSC, EMB, CD36, SOCS2, CD3D, CALCRL, CASP8, TMSB10, BMP6, BCL2, NAMPT, GRK2, IL32, CREM, SOCS1, SLC7A5, CIDEC, FCGR3B, F13A1, ETS2, FYB1, TNFAIP6, CYP1A1, ASRGL1, UPP1, MMP9, MMP3, VEGFA, CCR5, FLG, CXCL10, IL1B, MAPK1, CCL27, TRPA1, AHSA1, TRPV1, AIMP2, CCL17, IL16, CCL2, POLDIP2, CD1D, CRK, MAPK14, GADD45G, CXCR3, GRAP2, RNF19A, IL9, TDGF1P6, CABIN1, MIR155, MIR126, HRNR, LCE3C, CXCR6, LCE3B, IL33, ELOVL6, RABGEF1, TRPV4, ACKR3, SUCNR1, PCLAF, IL23A, IKZF1, IL22, IL26, NAT2, LPAR2, ACE, GRP, GPR42, CCR10, FN1, EPHB2, EGFR, EDNRA, CSF2, HIF1A, CNR2, CD70, CD80, CD1A, BRS3, ARG1, ADRA2B, GZMB, HLA-DQA1, SOCS3, PPARG, TLR4, TDGF1P3, STAT3, SSTR4, SDC1, CXCL11, CCL8, ADRA1A, NR4A1, POMC, ORM1, MMP12, MAP3K5, IL17A, IL6, IL1RN, PPARA
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Spinocerebellar Ataxia Type 37
Gene_reviews
In most individuals, the initial signs/symptoms include falls, dysarthria, or clumsiness followed by a complete cerebellar syndrome. A distinctive clinical feature is the presence of altered vertical eye movements in early stages of the disease, even preceding ataxia symptoms. ... For most affected Spanish individuals, the initial symptoms included falls, dysarthria, and/or clumsiness, followed by a complete cerebellar syndrome. As a distinct clinical feature, abnormal vertical eye movements were detected in early stages of the disease [Serrano-Munuera et al 2013, Corral-Juan et al 2018]. ... SCAs with a Pure Cerebellar Phenotype to Consider in the Differential Diagnosis of SCA37 View in own window Disorder Gene Phenotype Comments SCA5 (OMIM 600224) SPTBN2 Pure slowly progressive cerebellar syndrome Onset age range: 10-68 yrs; congenital & infantile onset also reported Downbeat nystagmus, impaired smooth pursuit, & gaze-evoked nystagmus Slower progression than in SCA37; persons w/SCA5 remain ambulatory despite long disease duration. ... SCA31 (OMIM 117210) BEAN1 Pure cerebellar syndrome Variable hearing loss of cochlear origin Hearing loss of cochlear origin was reported in 1 person w/SCA37 but did not appear related to SCA37. ... Specific assessment of the cerebellar cognitive affective syndrome may be considered. Brain MRI examination Consultation with speech, physical, behavioral, and occupational therapists Consultation with a clinical geneticist and/or genetic counselor Treatment of Manifestations No curative treatment is available for individuals with SCA37.
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Lichen Planus Pemphigoides
Gard
Lichen planus pemphigoides (LPP) is a rare cross-over syndrome between lichen planus and bullous pemphigoid .
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Distal Trisomy 5q
Orphanet
Distal trisomy 5q is a rare chromosomal anomaly syndrome, resulting from a partial duplication of the long arm of chromosome 5, characterized by short stature, moderate intellectual disability, and craniofacial dysmorphism (microcephaly, flat facies, large, low-set dysplastic ears, down-slanted, almond-shaped palpebral fissures, hypertelorism, epicanthal folds, small nose, long philtrum, small mouth with thin upper lip, and micrognathia).
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Rhiny
Omim
Mindikoglu et al. (1990) suggested the term craniorhiny for the syndrome that combines craniosynostosis with unusual nasal abnormalities (123050) and rhiny for this condition.
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Polymyalgia Rheumatica
Orphanet
Muscle tenderness, peripheral synovitis, arthritis, carpal tunnel syndrome or distal tenosynovitis, as well as non-specific symptoms, such as fatigue, asthenia, malaise, low-grade fever, anorexia and weight loss, may be associated.HLA-DRB1, RBM45, CRP, IL6, SMUG1, CCL5, ACR, GCA, IL10, IL6R, ICAM1, IFNG, TNF, IL1RN, HLA-DQA1, PTPN22, PIK3CD, CD274, KLRK1, MBL3P, SOST, TSBP1, IL32, TRAF6, FIP1L1, TLR4, WG, RHCE, PTX3, PIK3CG, NFKB1, PIK3CB, PIK3CA, ANGPT2, CCR5, CRH, ESR1, HLA-A, HLA-DQB1, IL1A, IL1B, IL2RA, IL4, ISG20, KRT15, MBL2, MX1, ALB, NOS3, PDCD1, KLRC4-KLRK1
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Mosaic Trisomy 9
Orphanet
Mosaic trisomy 9 is a rare chromosomal anomaly syndrome, with a highly variable phenotype, principally characterized by intellectual disability, growth and developmental delay, facial dysmorphism (incl. microphthalmia, deep-set eyes, low-set, malformed ears, bulbous nose, high-arched palate, micrognathia) and congenital heart defects (e.g. ventricular septal defect), as well as urogenital (e.g. hypoplastic genitalia, cryptorchidism), skeletal (congenital joint dislocations or hyperflexion, scoliosis/kyphosis) and central nervous system anomalies (hydrocephalus, Dandy-Walker malformation).