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Fish Allergy
Wikipedia
The four types of hypersensitivity reaction are: type 1, immediate IgE-mediated; type 2, cytotoxic; type 3, immune complex-mediated; and type 4, delayed cell-mediated. [28] The consequent pathophysiology of allergic responses can be divided into two time periods. ... "Seafood allergy: A comprehensive review of fish and shellfish allergens". Mol. Immunol . 100 : 28–57. doi : 10.1016/j.molimm.2018.04.008 . ... Archived from the original on 2009-06-28. ^ Grimbaldeston MA, Metz M, Yu M, Tsai M, Galli SJ (2006). ... "Fish intake during pregnancy or infancy and allergic outcomes in children: A systematic review and meta-analysis". Pediatr Allergy Immunol . 28 (2): 152–61. doi : 10.1111/pai.12648 .
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Hemorrhoid
Wikipedia
] weakly recommend the use of phlebotonics in the treatment of the symptoms of haemorrhoids grade I to II, [22] [28] [29] [30] [31] [32] [ excessive citations ] although these drugs are not approved in the United States as of 2013 [update] [33] and in Germany, [34] and restricted in Spain for the treatment of chronic venous diseases. [35] Procedures A number of office-based procedures may be performed. ... This procedure can be done using electrocautery , infrared radiation , laser surgery , [1] or cryosurgery . [36] Infrared cauterization may be an option for grade I or II disease. [6] In those with grade III or IV disease, reoccurrence rates are high. [6] Surgery A number of surgical techniques may be used if conservative management and simple procedures fail. [6] All surgical treatments are associated with some degree of complications including bleeding, infection, anal strictures and urinary retention , due to the close proximity of the rectum to the nerves that supply the bladder. [1] Also, a small risk of fecal incontinence occurs, particularly of liquid, [2] [37] with rates reported between 0% and 28%. [38] Mucosal ectropion is another condition which may occur after hemorrhoidectomy (often together with anal stenosis). [39] This is where the anal mucosa becomes everted from the anus, similar to a very mild form of rectal prolapse . [39] Excisional hemorrhoidectomy is a surgical excision of the hemorrhoid used primarily only in severe cases. [1] It is associated with significant postoperative pain and usually requires two to four weeks for recovery. [1] However, the long-term benefit is greater in those with grade III hemorrhoids as compared to rubber band ligation. [40] It is the recommended treatment in those with a thrombosed external hemorrhoid if carried out within 24–72 hours. [6] [12] Evidence to support this is weak, however. [21] Glyceryl trinitrate ointment after the procedure helps both with pain and with healing. [41] Doppler-guided transanal hemorrhoidal dearterialization is a minimally invasive treatment using an ultrasound Doppler to accurately locate the arterial blood inflow. ... Japan Journal of Nursing Science : JJNS . 8 (2): 115–28. doi : 10.1111/j.1742-7924.2011.00175.x . ... S2CID 4198610 . ^ "Balsam of Peru contact allergy" . Dermnetnz.org. December 28, 2013. Archived from the original on March 5, 2014 . ... Jan 8, 2008. Archived from the original on 28 November 2012 . Retrieved 17 September 2012 . ^ "Beck From the Dead" .
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Autism
Wikipedia
Specialty Clinical psychology , psychiatry , pediatrics , occupational medicine Symptoms Trouble with social interaction , limited communication , restricted interests, repetitive behavior [1] Complications Social isolation, employment problems, family stress, bullying , self-harm , suicide [2] [3] [4] Usual onset By age two or three [5] [6] Duration Lifelong [5] Causes Genetic and environmental factors [7] Diagnostic method Based on behavior and developmental history [5] Differential diagnosis Reactive attachment disorder , intellectual disability , schizophrenia [8] Treatment Behavioral therapy , speech therapy , psychotropic medication [9] [10] [11] Medication Antipsychotics , antidepressants , stimulants (associated symptoms) [12] [13] [14] Prognosis Frequently poor [15] Frequency 24.8 million (2015) [16] Autism is a developmental disorder characterized by difficulties with social interaction and communication, and by restricted and repetitive behavior. [6] Parents often notice signs during the first three years of their child's life. [1] [6] These signs often develop gradually, though some children with autism experience worsening in their communication and social skills after reaching developmental milestones at a normal pace. [17] Autism is associated with a combination of genetic and environmental factors . [7] Risk factors during pregnancy include certain infections, such as rubella , toxins including valproic acid , alcohol, cocaine , pesticides , lead , and air pollution , fetal growth restriction , and autoimmune diseases . [18] [19] [20] Controversies surround other proposed environmental causes ; for example, the vaccine hypothesis , which has been disproven. [21] [22] Autism affects information processing in the brain and how nerve cells and their synapses connect and organize; how this occurs is not well understood. [23] The Diagnostic and Statistical Manual of Mental Disorders (DSM-5), combines autism and less severe forms of the condition, including Asperger syndrome and pervasive developmental disorder not otherwise specified (PDD-NOS) into the diagnosis of autism spectrum disorder (ASD). [6] [24] Early behavioral interventions or speech therapy can help children with autism gain self-care , social, and communication skills. [9] [10] Although there is no known cure, [9] there have been cases of children who recovered. [25] Some autistic adults are unable to live independently. [15] An autistic culture has developed, with some individuals seeking a cure and others believing autism should be accepted as a difference to be accommodated instead of cured. [26] [27] Globally, autism is estimated to affect 24.8 million people as of 2015 [update] . [16] In the 2000s, the number of people affected was estimated at 1–2 per 1,000 people worldwide. [28] In the developed countries, about 1.5% of children are diagnosed with ASD as of 2017 [update] , [29] from 0.7% in 2000 in the United States. [30] It occurs four-to-five times more often in males than females. [30] The number of people diagnosed has increased dramatically since the 1960s, which may be partly due to changes in diagnostic practice. [28] The question of whether actual rates have increased is unresolved. [28] Contents 1 Characteristics 1.1 Social development 1.2 Communication 1.3 Repetitive behavior 1.4 Other symptoms 2 Causes 3 Mechanism 4 Diagnosis 4.1 Classification 4.1.1 Spectrum 5 Screening 6 Prevention 7 Management 7.1 Education 7.2 Medication 7.3 Alternative medicine 8 Prognosis 9 Epidemiology 10 History 10.1 Clinical development and diagnoses 10.2 Terminology and distinction from schizophrenia 11 Society and culture 11.1 Autism rights movement 11.2 Employment 12 References 13 External links Characteristics Autism is a highly variable, neurodevelopmental disorder [31] whose symptoms first appear during infancy or childhood, and generally follows a steady course without remission . [32] People with autism may be severely impaired in some respects but average, or even superior, in others. [33] Overt symptoms gradually begin after the age of six months, become established by age two or three years [34] and tend to continue through adulthood, although often in more muted form. [35] It is distinguished by a characteristic triad of symptoms: impairments in social interaction, impairments in communication, and repetitive behavior. ... Intrauterine growth restriction is associated with ASD, in both term and preterm infants. [19] Maternal inflammatory and autoimmune diseases may damage fetal tissues, aggravating a genetic problem or damaging the nervous system. [20] Exposure to air pollution during pregnancy, especially heavy metals and particulates, may increase the risk of autism. [79] [80] Environmental factors that have been claimed without evidence to contribute to or exacerbate autism include certain foods, infectious diseases , solvents , PCBs , phthalates and phenols used in plastic products, pesticides , brominated flame retardants , alcohol , smoking, illicit drugs , vaccines , [28] and prenatal stress . Some, such as the MMR vaccine, have been completely disproven. [81] [82] [83] [84] Parents may first become aware of autistic symptoms in their child around the time of a routine vaccination. ... Most recent reviews tend to estimate a prevalence of 1–2 per 1,000 for autism and close to 6 per 1,000 for ASD as of 2007. [28] A 2016 survey in the United States reported a rate of 25 per 1,000 children for ASD. [171] Globally, autism affects an estimated 24.8 million people as of 2015 [update] , while Asperger syndrome affects a further 37.2 million. [16] In 2012, the NHS estimated that the overall prevalence of autism among adults aged 18 years and over in the UK was 1.1%. [172] Rates of PDD-NOS 's has been estimated at 3.7 per 1,000, Asperger syndrome at roughly 0.6 per 1,000, and childhood disintegrative disorder at 0.02 per 1,000. [173] CDC estimates about 1 out of 59 (1.7%) for 2014, an increase from 1 out of every 68 children (1.5%) for 2010. [174] The number of reported cases of autism increased dramatically in the 1990s and early 2000s. ... The sex ratio averages 4.3:1 and is greatly modified by cognitive impairment: it may be close to 2:1 with intellectual disability and more than 5.5:1 without. [28] Several theories about the higher prevalence in males have been investigated, but the cause of the difference is unconfirmed; [177] one theory is that females are underdiagnosed. [178] Although the evidence does not implicate any single pregnancy-related risk factor as a cause of autism, the risk of autism is associated with advanced age in either parent, and with diabetes, bleeding, and use of psychiatric drugs in the mother during pregnancy. [177] [179] The risk is greater with older fathers than with older mothers; two potential explanations are the known increase in mutation burden in older sperm, and the hypothesis that men marry later if they carry genetic liability and show some signs of autism. [31] Most professionals believe that race, ethnicity, and socioeconomic background do not affect the occurrence of autism. [180] Several other conditions are common in children with autism. [23] They include: Genetic disorders .CHD8, NRXN1, TBR1, SHANK1, PAX6, MECP2, NLGN3, ADNP, UBE3A, NLGN4X, FMR1, MAOA, SHANK3, PTEN, CNTNAP2, IL1RAPL1, TMLHE, CACNA1C, TSC2, KDM5C, SYNGAP1, CHRNA7, PTCHD1, GRIN2B, MACROD2, COMT, ADSL, JMJD1C, IFNG, CSDE1, NTRK2, NSD1, SNRPN, GABRB3, OXTR, MTHFR, BDNF, EN2, SLC25A12, DPYD, SLC6A4, TAF1C, RELN, AVP, FOXP2, DHCR7, BRSK2, MET, RBFOX1, HOXA1, IL6, AVPR1A, GRIK2, DISC1, ITGB3, WNT2, PRKN, NLGN1, GAD1, GLO1, HTR2A, HLA-DRB1, NBEA, NRCAM, NF1, DOCK4, CADPS2, NOS2, ATP10A, AR, ADA, MAPK3, AHI1, CNTN4, ASMT, SHANK2, TPH2, SEMA5A, POMC, LEP, ST8SIA2, ITGA4, PRKCB, MAGEL2, DAB1, GABRA5, NRP2, GABRA4, GABRB1, NRXN3, IMMP2L, LAMB1, DRD3, OXT, SCT, BCL2, TSC1, NRXN2, IL10, SLC9A9, EIF4E, SND1, DLX2, PIK3CG, DRD1, DLGAP2, SERPINE1, IGF1, EGF, HRAS, MEF2C, DIPK2A, TBL1XR1, C4B, RPL10, STK39, PTGS2, AGAP1, MARK1, PRL, STX1A, PON1, EXT1, CACNA1H, GRIA1, GPX1, GRM8, KDM5B, VLDLR, GABBR1, VIP, CADM1, FARP2, GRIN2A, GSTM1, UBE2H, RIMS1, SEZ6L2, HLA-A, VWA8, TRRAP, HOXD11, PASK, EGR2, HDLBP, ZMYND11, GJA1, ROBO3, AQP4, ABAT, KCND2, PCDH10, PITX1, MYO1D, SLC19A1, CDH10, PLA2G4A, CDH9, STXBP6, SCAMP5, SLC1A3, LASP1, MAOB, HTR3C, APC, MIF, RORA, DIXDC1, ROBO2, ROBO1, CSMD3, RAB39B, CHRNA4, CHRNB2, CYP19A1, ROBO4, TNFRSF1B, DHFR, NPAS2, ACE, ASIC2, SNTG2, REEP3, HTR3A, DLX1, ADRB2, PDE4A, IL4, IL5, TDO2, GABBR2, CP, PDE4B, PECAM1, PER1, HTR5A, PRF1, NTF4, RNF8, NR4A2, CNTN3, PLAUR, MBD4, HTR1D, PRLR, MTF1, HTR1B, HTN1, IGF2, IGFBP3, TF, IL1RN, IL2, IL13, IL15, XDH, XPC, INPP1, KCNMA1, LZTR1, GZMB, GSTP1, SLC6A8, SCN7A, MCC, TCN2, STATH, SLC40A1, KIF1A, GABRA2, GABRA1, COP1, JAKMIP1, GPR155, POU6F2, DAO, BTD, NTF3, ZNF292, KAT8, KMT2E, ASTN2, CALCA, CAT, CHD4, GABRA3, RAB11FIP5, AGO1, ZNF713, GHR, DLL1, ACADSB, MIR23A, MIR106B, ADM, CUL7, WDFY4, PLD5, MBD3, UPB1, FBXO40, AUTS2, PIANP, FOXP1, SCN2A, CTNND2, CDKL5, EHMT1, MED12, ANKRD11, STS, STXBP1, CREBBP, GTF2I, UPF3B, SLC1A2, AKT1, BCKDK, PIK3CA, GABRD, RAI1, RAC1, CHD7, TRIM33, CACNA1A, HNF1B, ATRX, SCN1A, DHDDS, SCN8A, LIMK1, SOX2, PAH, OPHN1, MACROD2-AS1, HDAC8, GABRB2, GABRG2, SATB2, CLIP2, EP300, ELN, SLC9A6, CYFIP2, IQSEC2, PPP3CA, MAN1B1, PPL, PRKAR1A, HESX1, IRAK1BP1, PROKR2, PARD3B, ZNF827, NUS1, RLIM, SYNJ1, CNKSR2, TRAK1, TMEM132B, KCNAB2, RAD21, REV3L, RFC2, DNER, NAV3, FOXN1, TRAF7, DHX30, RREB1, SORCS1, FLCN, POLG, ARNT2, SCN1A-AS1, SLC44A3-AS1, SEMA3E, RPH3AL, PIGL, OTX2, AUTS1, KLLN, PKMP1, LIPG, HDAC4, SLC23A2, SEC23B, SMC3, HCN1, PC, FLG-AS1, LAMA1, PDE4D, SLC13A5, BAZ1B, SDK1, SLC39A11, PKP2, RYR1, RASSF5, SMC1A, PLXND1, SOX3, SOX11, PRR12, FMN2, SIN3A, GTF2IRD1, SH2B1, YEATS2, TBX1, TCF20, SLC22A15, PARS2, SLC35C1, SETD5, PHIP, CDKAL1, NECAP1, DYM, TMCO1, UFD1, TBL2, WWOX, HIRA, FAM135B, TRPS1, NIPBL, YWHAG, NUFIP2, SDHD, ACTL6B, SCN3A, SYNE2, UBA5, AP3B2, ALG13, SZT2, SRD5A3, ALDH5A1, SDHB, SDHC, ALMS1, PCGF2, SIM1, SKI, GALNT14, GNPTAB, MED13L, PCDH15, ZBTB16, ARV1, GSPT2, PRDM16, SLC22A3, SEC24C, AARS1, COX3, TRNQ, COL4A2, COX1, COL6A1, COX2, ARSD, ND1, ND4, FLG, ND5, FGFR1, ND6, FGF14, TRNF, FGF12, TRNH, FER, FBN1, BRCA2, MSNP1, CLTC, MEIS2, CAMK2G, GRIN2D, LHX1, CACNA1B, GP1BB, ALDH1A3, GJB2, GJA8, RERE, GJA5, KCNB1, CHRNA1, GATM, KMT2A, KCNA2, GAMT, TRNL1, GUCY1A2, TRNS1, NDP, ATP6V1A, DNM1, EEF1A2, ARVCF, BPTF, NHS, ERBB4, ERG, NELL1, NONO, NAGLU, TRNS2, NAGA, TRNW, CD38, CYFIP1, HTC2, APP, DNTT, MUL1, CBLL2, IL17A, TNF, ARID1B, MBD1, DYRK1A, NOS1, MRC1, MTOR, PVALB, FRAXA, VDR, GRPR, ADORA2A, NCS1, APOE, NLGN4Y, FMR1-IT1, ZNF804A, SYN1, PCDH19, CARS1, RSS, LOC110806262, SMS, SMARCA1, MTR, DBH, GABRG3, DDC, SLC18A1, GRM5, ARX, HOXB1, DRD4, RBM45, AUTS5, DLG4, NCAM1, RAPGEF4, YWHAE, GFAP, GRIP1, TP53, TRIO, TPH1, VIPR2, PCLO, HTT, CACNA1D, HTR2C, CAPS2, KATNAL2, HLA-G, HLA-B, HLA-DPB1, NRAS, CEP290, DLX5, PHB2, CC2D1A, FAAH, DLD, DLG3, ESR2, DLX6, GRIK4, EPHB2, IL22, ZBTB20, IL1RAPL2, DRD2, DPP4, FAM120C, AMBRA1, MBD5, CNR2, GAD2, GPHN, ABCB6, RIMS3, ARHGAP32, CLOCK, CHAT, NLGN2, GLUL, CDH13, CELF6, TOP3B, WASF1, ATP2B2, DNMT1, MIR137, PIK3CD, SOAT1, PAFAH1B1, RIT2, ANK3, SMARCA4, PTPRZ1, LRFN5, SLC12A2, HEPACAM, SNAP25, PIK3CB, PTLS, ACAN, APRT, ACTB, NDN, CLIP1, AMPD1, TCF4, TAC1, MFAP1, CADM2, MAPK1, MFGE8, NIPA1, MEF2A, OPRM1, MTRR, NCAM2, NEGR1, CCL2, ADCY1, CRP, LSG1, CTSB, MIR137HG, MIR124-1, TESC, CTLA4, CTNNB1, SLC52A1, NOTCH2NLA, CSF2, QRSL1, CS, RPP25, C4orf3, TADA1, CHDS3, PCDHB4, CHPT1, ANKS1B, CELF4, SPHK2, CLK2, SLC2A4RG, RETN, CTNNBL1, HCA1, ANKH, NSMCE3, AGTR2, DNAAF3, MYDGF, CMAS, AGT, AGRP, AGER, EAF2, PAG1, ARSI, CNTF, FCRL6, ZNF407, WDR11, CYP1B1, CTSD, HYDIN, ACACA, DMD, FOXP3, TAS2R1, TAS2R3, LINC01672, IL21R, NT5C, DEL11P13, VSX1, NOTCH2NLC, NOTCH2NLB, ABO, MYLPF, ABCA3, STRN4, THRIL, DNASE1L3, CTNNA3, PYCARD, DYNC1H1, LOC102724334, SETD2, THRA1/BTR, MCTS1, SYNSTH, ADHD6, ACHE, MIR486-1, CUX1, LRRN3, GNB1L, ADARB1, CYP2D6, BDNF-AS, CYP11B1, H4C15, CYP21A2, DAB2, TREM2, DCUN1D1, WAC, H2BS1, IL17D, ADA2, ZNF674, DECR1, SCLY, MIR557, ZGLP1, VCX3A, ACP1, SPG21, PCBP4, FOXK1, SENP7, ATP13A4, C5, SIK1, H2BC12, COMMD1, ZNF385B, EBPL, NTNG2, KIRREL3, TMEM185A, SRRM4, MEGF10, RNF135, PPP1R1B, RPS10P2, UPP2, CTTNBP2, FERMT3, FAM107B, CACNB2, TTC25, PCDH11Y, APBA2, NETO1, DIAPH3, NDEL1, STMN4, BST1, AREG, AS3MT, SYTL4, ASTN1, ASL, OMA1, H4-16, AVPR2, TUBGCP5, ADGRB3, MBD6, AGBL1, PGLYRP2, CEP41, DUSP15, TNFRSF17, RHOT2, XIRP2, OPN1SW, HTR7P1, CNTNAP5, BMPR2, SNX29, FAM43A, CHURC1, NOBOX, UBXN11, ARNTL, DOCK11, SPX, SRCIN1, ABCA13, TSHZ3, CLSTN2, CDH11, AMY1B, AMY1A, RIC8A, PPCDC, IL21, ZNF410, FBXO15, LRRC4C, CDH15, VPS18, PREX1, CPED1, CDK5, ATOH7, CECR, LRFN2, MRTFB, ALDH2, ALB, ATD, IL27, CHRM3, KCTD13, SLC12A5, CDH8, TOR3A, CDH7, CD69, CALB1, CALB2, VPS13B, CAST, LINGO2, MCPH1, CASP3, SH3TC2, SERPINH1, SLC35G1, CARS2, CBS, FA2H, MLPH, CUEDC2, DNAAF4, VKORC1, WNK3, CD5L, ANK2, CD40LG, SIL1, ANK1, ZNF778, AMY1C, DAGLA, WDFY3, DESI1, IL1B, IL18, IL16, IL9, CXCL8, TERF1, TERT, TG, SYP, TGFB1, TH, THBS1, THRA, TLL1, TSPAN4, TAL1, SYN2, TPTE, SRC, KCNJ10, SOD1, SOD2, SOS1, KCNJ1, SP1, SRY, INSR, SST, SSTR5, STAT3, ITIH3, ITGAV, ITGA6, TNC, TRH, SNCG, RASSF7, PXDN, HGF, HFE, FZD3, SEM1, GLRA3, HCCS, LRP8, AKAP1, BAS, DGCR6, H2AZ1, USP9X, H1-4, NRG1, UBE2K, TRPC6, HP, HTR7, HTR4, HTR1A, TXN, HPD, UCP3, UROD, MKRN3, HOXD@, HMGN1, WT1, HLA-DPA1, XPO1, HLA-DOA, SNRNP70, SNCB, DNMT3A, PPP2R5D, NDUFA5, PENK, PIGH, PLP1, PPARD, PPARG, MAPK7, PCDH9, PRODH, MTHFD1, PSD, PTPRF, PURA, RAB3A, NEDD4, NEUROG1, RARA, NPTX2, NTS, NUP98, NPY1R, OCRL, OGG1, OMG, OTX1, NFE2L2, NPY, NOTCH1, PCSK6, NFKBIL1, NFIC, PAX3, MT3, RASGRF1, SMARCA2, LAMC2, LTA, LMX1B, SHMT1, SHMT2, LEPR, SLC1A1, L1CAM, SDC2, SLC6A3, KRT7, KIR3DL1, SLC12A3, KIR2DS1, KCNQ2, MAFD2, CXCL5, OPN1LW, RORC, REN, UPF1, MT1A, RFC1, MOV10, MMP9, RYR2, CCL22, RYR3, S100B, MEST, MBP, MAP2, CCL17, GUK1, H4C9, H4C1, FGFR2, CHP1, FOLR1, DLGAP4, NTNG1, FOLH1, FLT4, FAN1, FOSL2, NT5C2, MAST1, NPY5R, MYT1L, SETD1B, KDM4C, DCTN3, PTENP1, FAP, CHL1, ATP8A1, DEAF1, KAT5, GNB5, GABRG1, GABPA, XRCC6, ZNF277, LYVE1, EHD1, RAB40B, SLC27A4, SLC27A3, SPACA9, POGZ, PHF8, H4C4, GREM1, ELAVL2, PLEKHG3, SETBP1, EIF4EBP2, EBF1, DSCAM, COPG2, ENO2, AKAP8L, DPYSL2, ACAD8, DPP6, AGO2, CNTN6, ELK3, PART1, DIP2A, SYNM, ACSL4, ARHGEF9, FABP7, MCF2L, CUX2, F2RL1, CRTC1, EPS8, EZH2, SLC35A3, MAPK8IP2, PSD4, SH3BP4, SHC2, SEMA3A, AKR1A1, BCAS2, AP1S2, MPDZ, BANF1, GRM7, GRM1, CCN6, NR1I2, GRIN1, KLF7, CACNA1G, GRIK1, GRID2, GRIA2, GPR37, PKD2L1, EIF3A, GRP, AKAP8, H4C5, H4C6, H4C12, H4C11, H4C3, H4C8, H4C2, H4C13, CASK, H4C14, GNPAT, CUL3, GSK3B, CNTNAP1, DENR, GPR35, ARTN, ARHGEF2, GCG, BMS1, PTDSS1, RNF40, GEM, GDNF, SETDB1, RBM8A, XPR1, GATA4, SLC12A6, AKT3, RANBP9, TSPAN32, SPRY3, GH1, GLDC, MACROH2A1, GLP1R, MAGED1, GLRA2, HOMER1, ABCG2, GLRB, GLS, ADIPOQ, GMDS, LHX2, TAOK2, TRIP12, CYTH1, GOT2, STIN2-VNTR
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Acute Disseminated Encephalomyelitis
Wikipedia
., of MMR vaccine or smallpox vaccine) do not show increased risk of ADEM following vaccination. [9] [28] [29] [30] [20] [31] [32] [33] [34] [35] [36] An upper bound for the risk of ADEM from measles vaccination , if it exists, can be estimated to be 10 per million, [37] which is far lower than the risk of developing ADEM from an actual measles infection, which is about 1 per 1,000 cases. For a rubella infection, the risk is 1 per 5,000 cases. [31] [38] Some early vaccines, later shown to have been contaminated with host animal CNS tissue, had ADEM incident rates as high as 1 in 600. [28] In rare cases, ADEM seems to follow from organ transplantation . [20] Diagnosis [ edit ] ADEM term has been inconsistently used at different times [39] Currently, the commonly accepted international standard for the clinical case definition is the one published by the International Pediatric MS Study Group , revision 2007. [40] Given that the definition is clinical, it is currently unknown if all the cases with ADEM are positive for anti- MOG autoantibody, but in any case, it seems strongly related to ADEM diagnosis. [23] Differential diagnosis [ edit ] Multiple sclerosis [ edit ] While ADEM and MS both involve autoimmune demyelination, they differ in many clinical, genetic, imaging, and histopathological aspects. [14] [41] Some authors consider MS and its borderline forms to constitute a spectrum, differing only in chronicity, severity, and clinical course, [42] [43] while others consider them discretely different diseases. [6] Typically, ADEM appears in children following an antigenic challenge and remains monophasic. ... "Neurological complications of immunization". Ann. Neurol . 12 (2): 119–28. doi : 10.1002/ana.410120202 . PMID 6751212 . ... Thieme Medical Publishers" (PDF) . Semin Neurol . 28 (1): 84–94. doi : 10.1055/s-2007-1019130 .
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Disease X
Wikipedia
This makes it more likely new diseases will emerge but also modern travel and trade make it much more likely they will spread". [10] [26] H7N9 (2018) [ edit ] In 2018, a new strain of the H7N9 "bird flu" virus, with a 38 percent mortality rate, was likened to a potential Disease X by some international health authorities (but not the WHO, or the R&D Blueprint group). [27] [28] China would not share samples of the new H7N9 strain. ... "CEPI: Driving Progress Towards Epidemic Preparedness And Response" . Epidemiologic Reviews . 41 (1): 28–33. doi : 10.1093/epirev/mxz012 . ... Retrieved 20 March 2020 . ^ Hamblin, James (28 March 2020). "The Curve Is Not Flat Enough" . The Atlantic . Retrieved 28 March 2020 . ^ Simpson, Shmona; Kaufmann, Michael C.; Glozman, Vitaly; Chakrabarti, Ajoy (March 2020).
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Cancer
Wikipedia
These characteristics are required to produce a malignant tumor. They include: [28] Cell growth and division absent the proper signals Continuous growth and division even given contrary signals Avoidance of programmed cell death Limitless number of cell divisions Promoting blood vessel construction Invasion of tissue and formation of metastases [28] The progression from normal cells to cells that can form a detectable mass to outright cancer involves multiple steps known as malignant progression. [28] [29] Signs and symptoms Main article: Cancer signs and symptoms Symptoms of cancer metastasis depend on the location of the tumor. ... Characteristic abilities developed by cancers are divided into categories, specifically evasion of apoptosis, self-sufficiency in growth signals, insensitivity to anti-growth signals, sustained angiogenesis, limitless replicative potential, metastasis, reprogramming of energy metabolism and evasion of immune destruction. [28] [29] Epigenetics Main article: Cancer epigenetics The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis The classical view of cancer is a set of diseases that are driven by progressive genetic abnormalities that include mutations in tumor-suppressor genes and oncogenes and chromosomal abnormalities.KDM6A, CSF1R, KRAS, CDKN2A, BRCA1, MYC, NT5C2, CUX1, WRN, ATM, LIN28B, TRPV1, CTNNB1, VHL, ABCB1, VEGFA, YY1, ID1, VDR, PIK3CA, APOBEC3A, PIK3R1, FGFR1, ATR, IL1B, ESR1, AKT1, AKT2, ERBB2, ERBB3, ERCC1, MSLN, DLC1, NQO1, APC, DICER1, NOS3, NOTCH1, BAP1, ARID1A, NRAS, IL18, FASN, HMGA2, IL2, SF3B1, CCND1, CCND2, CCNE1, STK11, AURKA, GNAS, SST, UGT1A1, AKR1B10, GSTT1, SOD2, CDKN2C, CDKN2B, CDKN1B, CDKN1A, SKP2, SLC5A5, CDK6, CDK4, CCND3, RET, MSH3, CAT, HSF1, BLM, PPARA, MTOR, HRAS, BRAF, TPMT, MAP2K1, TP53, G6PD, TOP1, PTEN, PTGS2, SETD2, CD274, LIN28A, TERT, AHR, GPX3, LCN2, GPR55, KIT, EPHA2, NAT1, EPHA3, MRE11, TNFRSF10A, EGFR, APOBEC3B, KDR, MDM2, E2F1, DPYD, MET, GSTO1, PLAUR, SRF, OCLN, KCNH2, PDIA3, ATF2, MYOD1, SUZ12, MIR129-2, NACC1, ENOX2, CITED2, BIRC6, GLP1R, CRLF2, LTF, CAPN1, SNORD50A, SNORD50B, ARHGAP45, WDR74, PLEKHS1, DCUN1D3, DNAJC10, ASIP, DEK, TCF7L2, CDKN2B-AS1, PHB, FTO, TRPV6, SUGP1, PLCG1, RCAN1, FBN2, PIP, TNFAIP3, FADS1, FADS2, ZFHX3, SMARCAL1, CERT1, ZNF652, SIK3, GRHL1, LIPC, BAZ1B, CELSR2, ALDH1A2, MAML3, POLK, PPL, PIP5K1B, KCNE1, ABAT, ATP2B1, EIF4A1, GATA3, EIF4A2, GATA6, TFRC, TFPI, TG, THBD, THBS1, TGFA, GCKR, TGM2, GATA2, EIF4E, TGFBR2, TGFBR1, TGFBI, TFF3, GCG, TGFB1, TLR3, THY1, TOP2A, TP53BP1, TP73, TPD52, EIF4G2, TPM3, FUT4, TPT1, NR2C2, HSP90B1, FUS, GAST, TRAF6, EIF5A, F2RL3, HSP90B2P, TRPM2, NR5A2, EIF4G1, SOCS3, TIAM1, XRCC6, GAS6, TIMP1, TIMP2, GAPDH, EIF4EBP1, TIMP3, NKX2-1, TK1, TKT, TLR2, TFE3, TLR4, TMPRSS2, TNF, TNFRSF1A, GABPA, TNFRSF1B, TFF1, EPHX1, NR2F2, SFN, SP1, SPARC, MTA1, SPG7, SPINK1, SPINT1, GPI, SPP1, SRC, SRY, STAT5B, TRIM21, EGR1, SSTR4, SSX2, GNRH1, ST14, STAT1, STAT3, STAT5A, SOX9, CXCR3, SOX4, SOX2, SMARCA4, GPX1, GPT, SMARCB1, SNAI1, EXO1, SNCA, GPR42, SNCG, NEURL1, SLC16A3, FSCN1, SLC16A4, EGF, LATS1, SOAT1, GPER1, SOD1, SOS1, DIRAS3, STC1, TFAP2A, GH1, TCF4, TBX3, HNF1A, HNF1B, GJA1, GHSR, ZEB1, GHRH, FSHR, TRBV20OR9-2, SULT1E1, TDO2, PRDX2, TEK, TERC, GFAP, GEM, GDNF, TERF2, TFAM, GPC3, SPAG9, GLB1, TAZ, STIM1, CLDN1, PRC1, SULT1A1, SYK, SYT1, TAC1, ADAM17, TACR1, TAGLN, GLS, GLO1, MAP3K7, GLI2, GPRC5A, GLI1, TAL1, TAT, TBX1, GHR, UBE2I, TSC1, FANCD2, FAP, AXIN2, IQGAP1, PTK2B, CDC7, INPP4B, FZD4, FZD7, EPHA1, H4C4, EP300, FABP5, F9, F5, F3, SPOP, F2RL1, F2R, F2, EZH2, EPAS1, TKTL1, RECK, FOSL1, AIMP2, TFPI2, TUSC3, PSCA, CCDC6, ADAM12, RASSF7, FCGR3B, FCGR3A, KMT2D, NRP2, NRP1, TCL1A, SLC7A5, MIA, MLRL, NCOA3, TAM, USP9X, FAT1, NR0B2, CUL4B, TSC2, TNFRSF11A, BECN1, ERCC5, ERCC4, PEA15, ABCC3, MBTPS1, ERCC2, TNFRSF10B, ERBB4, EPHB2, ERG, RIPK1, EPHB4, TNFSF13, TNFSF10, EPOR, TNFRSF6B, EPO, TNFSF9, ADAM9, EIF3A, ERN1, CUL4A, TP63, PPM1D, EWSR1, LGR5, MECOM, ETV6, BHLHE40, ETV4, TNFSF11, ETV1, ETS1, TNKS, AKR1C3, NCOA1, NUMB, ESRRB, SOCS1, ESR2, BANF1, DYNLL1, IL18R1, FEN1, TFEB, USP7, ELK3, UGT1A, FN1, NR1H2, ZPR1, SQSTM1, UVRAG, SPHK1, FLT4, VAV1, FLT3, FOLR1, FLT1, FLOT2, VCP, VDAC1, FLNA, ARHGEF7, PER2, NR1I2, FLI1, FOLH1, FOLR2, FGF1, TXNRD1, TSG101, TSHR, HSPB3, FRA16D, TTK, ELAVL2, TWIST1, TNFRSF4, TXN, ELAVL1, FOS, MBD2, TYMS, TYRO3, UBE3A, UCHL1, UCP2, UGCG, FOSB, BCL10, VEGFC, KAT2B, GPX4, CCN4, FHIT, FH, XRCC1, XRCC3, FGFR4, FGFR2, FGFR3, ENO1, XRCC5, YWHAZ, FOXO3, ZFP36, ZFX, FGF7, SLC30A3, PRDM2, CFLAR, PAX8, CXCR4, FGF2, XPO1, XPC, XIST, XBP1, FOXO1, FOXM1, EZR, FOXC2, VIM, VIP, PROM1, FOXC1, VWF, WEE1, FKBP5, FKBP4, WNT1, WNT2, WNT5A, CTTN, HDAC3, WT1, ENG, KCNE2, MAP2K4, HLTF, NOS1, ING1, IDO1, NPY, NOTCH2, NOTCH3, ILK, NPC1, NPM1, IL17A, TNFRSF9, IL16, YBX1, IL15, IL13RA2, NT5E, IL13, NTRK1, NTRK2, ROR1, NTS, IL11, IL10, NTSR1, NOS2, CXCL10, NUP98, NNMT, CEACAM6, NBN, NCAM1, ISG20, IRS1, NCL, NEDD8, IRF4, NEDD9, NEK2, NEU1, NEUROD1, NF1, NF2, NFE2L2, NFKB1, NFKB2, INSR, NGF, NGFR, NHS, NM, NME1, CXCR2, ODC1, MYCN, IGFBP7, PAX2, PAX3, IGFBP3, IGFBP2, PAX5, IGF2R, IGF2, IGF1R, IGF1, PCNA, IFNG, IFNB1, CDK16, PDCD1, PDGFRA, IFNA13, PDGFRB, IFNA1, PDK1, PDPK1, PECAM1, SERPINF1, PFKFB3, PAWR, CCN1, CXCL8, IGH, OGG1, IL7, IL6ST, TNFRSF11B, IL6, IL4R, IL4, OSM, P2RX5, P2RX7, P4HB, IL2RA, IL1RN, PEBP1, PAEP, IL1A, IKBKB, PRDX1, SERPINE1, SERPINB2, PAK1, REG3A, PRKN, MYD88, ITGA5, GRB2, SMAD4, MAGEA1, MAGEA3, LAG3, MAL, L1CAM, MBL2, KRT19, MC1R, MCAM, MCL1, MCM7, CD46, MDK, MDM4, KPNA2, MECP2, KIF22, MEN1, MFAP1, KITLG, MGMT, CD99, MITF, SMAD7, SMAD3, KLK1, SMAD2, LGALS9, LGALS7, LMNA, LGALS3BP, LGALS3, LGALS1, LMO2, LEPR, LEP, LOX, LOXL2, LPA, LDHA, LRP1, LRP6, LCK, TACSTD2, EPCAM, LASP1, STMN1, RPSA, MARCKS, MAD2L1, MKI67, KISS1, MYBL2, JAK3, JAK1, MST1, MST1R, MT1E, MTAP, COX1, COX2, NUDT1, ITPK1, MTHFR, MTTP, MUC1, MUC2, MUC4, MUC5AC, ITGB4, ITGB3, MMUT, ITGB1, ITGAV, MUTYH, MXI1, MYB, JAK2, JUN, MLH1, JUNB, KMT2A, KIR3DL1, MME, MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP11, MMP13, MMP14, CD200, MPO, MPZ, MRC1, ABCC1, KCNH1, MSH2, MSI1, CD82, MSMB, JUND, IFI27, PFKFB4, PGAM1, RELA, REST, HIF1A, HIC1, NRG1, HGF, RMRP, HFE, RNASE3, RNASEL, BRD2, ROCK1, HDGF, ROS1, RPE65, HDAC1, RPL17, RPS6KA3, RPS6KB1, RPS27, RRAS, RRM1, RRM2, S100A1, REN, REG1A, S100A6, HK1, RAD51, RAD51C, HMGB1, MOK, RAD52, HLA-G, RAF1, RAP1A, RARA, RARB, RARRES2, HLA-DRB1, PLAAT4, RASA1, RASGRF1, RB1, RBM3, HLA-DOA, OPN1LW, RECQL, HLA-C, HLA-A, HK2, S100A4, S100A8, IDUA, GSTM3, GSTM1, SFRP4, SRSF1, SGK1, GSN, GSK3B, GRPR, GRP, SHMT2, ST6GAL1, CXCL1, PMEL, SIX1, SLC1A5, NR3C1, SLC2A1, SLC9A1, GRN, SLC16A1, SLC22A3, SNAI2, SMARCA1, SMARCA2, GSTM2, SFRP1, S100A9, GSTP1, S100B, SATB1, SCD, CCL2, CCL5, H2AX, CCL18, CCL20, GZMB, CCL21, CXCL5, SDC1, SDCBP, CXCL12, GUCY2C, SDHB, SDHD, SELE, SELP, LPAR2, SET, GTF2H1, MSH6, RAC1, RAB5A, HMGA1, HSPB1, PMAIP1, PML, HSPA5, HSPA4, PMP22, PMS2, HSPA1B, HSPA1A, PODXL, POLD1, POLE, PON1, POU5F1, PRMT1, PPARD, PPARG, PPIA, AGFG1, PTPA, PRKAA1, PRKAA2, HPRT1, PRKAB1, HSPA9, HSPB2, HMMR, HSP90AA1, PGF, IDH2, IDH1, PGR, SERPINA1, PIK3CB, ICAM1, PIM1, PIK3CD, PIK3CG, IAPP, TNC, PIN1, PITX2, PKM, PLA2G1B, PLAG1, HTC2, PLAU, HSPG2, HSPD1, PLG, PLK1, PRKAR1A, HPGD, PRKCA, PRKCB, PTCH1, PTH, PTGS1, PTHLH, PTK2, PTK6, PTK7, HNRNPK, PTN, PTPN1, PTPN6, PTPN11, PTPRC, HNRNPA1, PTX3, PVR, HNF4A, PVT1, FOXA2, FOXA1, NR4A1, PXN, HMOX1, TAS2R38, HOXA9, PTBP1, PRNP, HP, PRKD1, PRKDC, MAPK1, MAPK3, MAPK7, MAPK8, MAP2K7, EIF2AK2, PRL, PROS1, HOXA11, PROX1, KLK7, KLK6, HTRA1, HOXB7, PSG2, PSMB9, PSMD2, PSMD9, PSMD10, EBAG9, KLF4, CD40, BUB1B, BTK, SLFN11, MTDH, DNER, KLF5, EGFEM1P, MUC16, PRRT2, CYTOR, BSG, BRS3, IL17F, AZIN2, BRCA2, NLRP3, CYGB, CGAS, C8orf34, BNIP3, ANIB1, LRG1, MRGPRX3, MRGPRX4, BUB1, TSPO, CDC42, C1QBP, PPP1R2C, PDCD1LG2, CD276, COL18A1, DDR1, CLPTM1L, TMX1, MAGED4B, CA9, ARHGAP24, CA2, SESN2, FSD1L, REG4, MAGT1, TCHP, MAK16, GLYR1, AFAP1-AS1, HAVCR2, ORAI1, WNT3A, IL33, LRRK2, BMP4, BMP2, BMI1, BARD1, ASXL1, BAG1, ZEB1-AS1, BACH1, THSD7A, B2M, GPRC6A, CTAG1A, IL27, AXL, CASC2, AVP, NUTM1, ATRX, MRGPRX1, COPD, NEAT1, HNF1A-AS1, LYPD5, KIAA0825, GADL1, STING1, BAX, DDX53, OXER1, BDNF, RBM45, ADAD1, SLCO6A1, GPR151, PRDM1, CKS1BP7, CTCFL, CEACAM1, BGN, PIWIL4, PWAR1, CBLL2, CNIH3, IL23R, BCR, PDIK1L, BCL9, PLB1, BCL6, BCL3, BCL2A1, BCL2, CALCA, TET1, ASRGL1, MIB1, ARHGEF2, CHPT1, SLC12A9, ENTPD1, CD38, ACKR3, CD36, CD34, PDXP, PCBP4, TNFRSF8, RAB25, CD80, CD28, CD27, CD22, CD248, MS4A1, CD19, SALL4, CEMIP, DANCR, AICDA, CD40LG, CD44, CD47, CD151, CDC25C, NLRP2, CDC20, CHFR, KDM3A, PAG1, HDAC8, PBK, CDK1, CDA, ACSS2, PNO1, MYDGF, TRPV5, DIABLO, CD74, CD70, TMPRSS4, MUC13, CD63, RETN, SLC2A4RG, NDRG2, MARCHF4, CALM1, MRTFA, WNK1, CASP9, CASP8, CASP7, GGCT, TRPM8, CASP3, CASP1, FSD1, CDC73, SLC52A2, MUL1, ROGDI, MCPH1, VTCN1, PALB2, MCTP1, NANOG, DHDDS, CALR, WLS, CALM3, CALM2, CASR, MARCKSL1, CAV1, GOLPH3, CD1D, CIP2A, ANKRD36B, TRIB3, HAMP, KMT2C, IL21, LGR6, GAS5, CCNB1, CCKBR, PINK1, CCK, SLC39A8, SOX17, GORASP1, SMURF2, SMYD3, CDCP1, RUNX3, RUNX1, RUNX2, ABCB5, MACC1, OR6V1, ADM, NR0B1, MIR424, AGTR1, AGT, JAG1, MIR429, AGER, AFP, MIR449A, MIR451A, MIR410, MIR494, MIR495, MIR497, ADRB2, MIR499A, MIR486-1, ADRA2B, ADRA1A, MIR455, PARP1, POU5F1P3, CRNDE, MIR375, MIR373, MIR335, VN1R17P, MIR34A, MIR34B, MIR93, MIR96, ALPP, MIR99A, ALPI, MIR17HG, ALOX15, ALOX5, ALK, MIR148B, AKR1B1, ZFAS1, GPR166P, ALDH1A3, ALDH2, ALDH1A1, MIR133B, ALCAM, ALB, MIR135B, LINC01184, POU5F1P4, AMH, UCA1, TMX2-CTNND1, KLRC4-KLRK1, COMMD3-BMI1, PCAT1, ACLY, LINC00457, CASC9, LINC01416, LIPC-AS1, ACACA, ABO, LINC02343, LINC02718, ABL1, LINC02030, MTCO2P12, MIR583HG, LOC110806263, H3P9, H3P8, H3P23, H3P10, NAT2, RPL17-C18orf32, ACP3, NAGPA-AS1, ADAR, CXADRP1, LGALS7B, ADH1C, ADH1B, MIR663A, MAGED4, POTEF, CCR2, HOTAIR, CD24, ADAM10, ACTB, ADA, TMED7-TICAM2, HOTTIP, LINC01592, LINC01672, LINC00867, CCAT1, ACTN4, GIMD1, MICA, MIR320A, MIR31, PWAR4, MIR193A, ARR3, MIR141, MIR142, MIR143, MIR144, MIR145, MIR146A, MIR148A, MIR149, MIR150, MIR152, MIR155, MIR15A, MIR15B, ARG1, MIR17, MIR18A, MIR182, AREG, MIR183, MIR186, AR, MIR191, MIR140, MIR139, ARSA, MIR106B, TICAM2, GSTK1, MALAT1, C17orf97, CASC15, LINC01194, MIR100, MIR106A, ATF4, ATF3, MIR107, MIR137, MIR10A, ASS1, MIR10B, MIR122, MIR125A, MIR126, ASAH1, MIR132, MIR136, STS, AQP5, MIR195, MIR30C2, MIR19A, MIR22, ANXA7, ANXA6, ANXA5, MIR221, MIR222, ANXA2, ANXA1, MIR223, MIR224, ANPEP, MIR23A, MIR25, ANGPT2, MIR26B, MIR27A, MIR29A, MIR296, MIR29B1, MIR29B2, MIR301A, MIR30A, MIR30C1, MIR217, MIR214, MIR212, MIR203A, FASLG, FAS, KLK3, APRT, APP, APOE, MIR20A, MIR200A, MIR200B, MIR200C, MIR204, MIR211, APOA1, MIR205, BIRC5, XIAP, BIRC3, BIRC2, APEX1, MIR206, MIR21, MIR210, ZCCHC8, LIF, CDH1, UBE2C, SEPTIN9, PPP1R13L, HPSE, LILRB1, SMR3B, CYP27B1, PPARGC1A, MALT1, CYP24A1, CYP19A1, GADD45G, CYP17A1, SUB1, SPIN1, RALBP1, CYP3A5, CYP3A4, STIP1, CKAP4, CYP2E1, CYP2D6, COPS5, IL24, KDM5B, NES, PLAC1, DCN, MRPL28, DDIT3, GADD45A, AHSA1, PDLIM5, TXNIP, PDPN, POSTN, IGF2BP1, ACE, IGF2BP3, PLK4, DCC, SPINT2, KHDRBS1, CXCR6, CTCF, DCTN6, DAZL, TNFSF13B, DAPK1, DAP, CYP2C9, CYP2B6, LPAR3, RPP14, CCN2, DKK1, TPX2, CTAG1B, KDM1A, KDM6B, CIC, CST3, TBC1D9, SULF1, SATB2, CSPG4, USP22, VCAN, SIRT3, SIRT1, ANGPTL2, BRD4, CBX7, SRRM2, PRAME, CSF3, CSF2, MEG3, CTLA4, MMRN1, CX3CR1, PTP4A3, FSTL1, CYP2A6, CYP1B1, CYP1A2, CYP1A1, CYLD, PSIP1, RASSF1, CXADR, WIF1, KLRK1, CTSS, CTSL, CHEK2, KLF8, MGLL, CTSD, CTSB, TDGF1P6, ZHX2, CTNND1, DDX3X, DDX5, AGR2, ZNRD2, NPEPPS, BAG3, PTGES, CXCL14, BCAR1, DUSP2, DUSP1, CLOCK, AKAP12, KLK4, TCL1B, ISG15, SEC14L5, SART3, HDAC9, KMT2B, PCLAF, MTSS1, ATN1, KEAP1, SPATA2, MELK, ZEB2, TBPL1, GDF15, ABCG2, ECM1, DCLK1, AURKB, PTTG1, EDNRA, IL32, EDN1, MSC, PDLIM7, PIWIL1, LIG4, CD163, NTN1, TYMP, SLIT2, PPIG, LONP1, KL, SLC9A3R1, ADIPOQ, COX5A, RECQL4, GRAP2, GAB2, MVP, FGF19, CFDP1, AKR1A1, SEMA3A, TUBB3, NDRG1, RACK1, NDC80, DHODH, DHFR, YAP1, PRMT5, GPNMB, IKZF1, TIMM8A, TACC3, MERTK, CLEC10A, SEMA4D, CIB2, DECR1, CIB1, KAT5, ATG7, DKC1, PAK4, DPP4, UST, NR1I3, SCO2, AKT3, DNMT3B, DNMT3A, DNMT1, HDAC6, BCL2L11, CHAF1A, ABCB6, RAD50, LILRB2, KIF20A, LRPPRC, TRAP1, SARDH, NAMPT, DMBT1, EBI3, TRIM28, TRIM13, CDK2AP2, CSF1, SIRT2, CHI3L1, UHRF1, NOB1, HIPK2, COL2A1, ATAD2, NXT1, PYCARD, TBK1, ZBTB7A, MCTS1, UBN1, EEF2K, RMC1, ABCC2, PSAT1, RRM2B, NOX4, DCDC2, CHEK1, CHUK, CEBPA, HSPA14, EML4, TRBVA, TRBV27, TRBC2, CDX2, CEACAM5, REM1, RGCC, CEBPB, LAMTOR2, CEBPD, CDK12, PINX1, RNF43, SIRT7, TET2, XAF1, COL11A2, CLU, TRAT1, FOXP3, SEMA5B, TMED7, ADIPOR1, TERF2IP, RMDN1, TLR9, CMA1, IL17D, ANGPTL4, ING4, LINC00328, DCTN4, LEF1, CKS1B, F11R, CEACAM7, TNFRSF12A, CFTR, TLR7, DELEC1, CISH, CFL1, GOLM1, PLCE1, UGT1A7, DLL4, CEACAM3, CCR7, IL22, CCR5, GEMIN4, PCA3, KRT20, ASAP1, TUG1, SGSM3, MCAT, CDK8, TNFAIP8, KLK5, CRK, IMP3, PRDX5, CDK2, PBRM1, RNF19A, TRIM33, WWTR1, CDK5, CREBBP, CREB1, SAMHD1, GDE1, LRIG1, IL23A, CRP, CDH13, CADM1, CHKA, WWOX, MAPK14, SMUG1, CRYZ, AMACR, IMPACT, RTEL1, NUP62, SH3BP4, SNHG1, LAPTM4B, FBXW7, TRIM29, SLC7A11, ZNF654, SF3B6, ANO1, CDK7, POLDIP2, IL37, CDO1, BBC3, DKK3, AGO2, MAP3K8, CEP55, PIWIL2, PDCD4, CDKN3, RBMS3, KLF6, COMT, HPGDS, RABGEF1, TMEM97, SIRT6, NOC2L, COX8A, RMDN3, CLDN7, PHGDH, GNL3, CHGA, CDK9, CPOX, CDKN1C, FOXP1, SMIM11A, CLDN3, CLDN4, ACAD8, LAT, PCDH10, STAT6, DLK1, MIR409, MIR452, SRA1, H4C15, RMDN2, S100A14, HNRNPDL, SYBU, CBFA2T2, SLC3A2, QRSL1, SMPD1, CDR1-AS, LOC102724971, LOC102723407, SHH, PRMT6, MXD1, SPHK2, MAOA, DNM1L, BCOR, MIR1246, MCM2, TRPM7, APLN, CASC11, VTRNA2-1, CX3CL1, SRPK1, EGLN1, MIR630, SSRP1, S100A7, SPN, CCT4, PTPRU, CTHRC1, PBX1, B3GAT1, XRCC2, MIR130B, FOXQ1, PAM, WDR5, TMSB4X, TSLP, SCLC1, OPRM1, TRIB2, BRIP1, THBS2, BCL2L12, RASSF5, MIR192, LATS2, NSD2, NTRK3, SETBP1, PLAT, SIK1, TYRP1, PIK3R2, TIGIT, MPEG1, PRIMA1, PPP1R13B, SIRPA, PRRX1, KDM4B, BRMS1, POT1, POMC, MSI2, H4-16, CHD5, WASF3, FLVCR1, CXCL16, TEAD1, PARG, HOXB13, FST, MIR34C, REL, MRPL41, BCL11B, MTR, XRCC6P5, NOD2, RHO, RIT1, MSR1, PRDM14, MIR340, MSN, MIR377, ASCC1, NEDD4, DOCK8, DAB2IP, STAG2, USP39, H4C9, TFF2, H4C1, H4C6, H4C12, NME2, H4C11, MIR215, H4C3, H4C8, H4C2, H4C5, H4C13, H4C14, MAD1L1, TMSB10, H3P40, RHOA, EFEMP1, ENO2, EDNRB, CCR4, IL9, VPS51, BAAT, CXCR1, ITGA6, DGKA, E2F4, DRD2, E2F3, LAMC2, F10, ANG, ARHGDIB, HOXD13, HES1, CD37, CBL, CASP10, DUSP6, HNRNPC, FOXL2, GPC1, CD14, ELANE, CD59, HMGCR, BIN1, TOPBP1, MIR338, SHBG, PIM2, USP1, HPS5, CYP2C19, SRSF3, SFRP2, SEMA6A, MIR326, CD8A, PHB2, TUSC2, GOPC, SHMT1, CCAR2, IMMT, KCNQ1OT1, P2RY12, MIR146B, SORD, MIR491, GSDME, CACUL1, SOX18, NSD1, PLD1, PLEC, IFIH1, AGRP, SLPI, DUXAP9, IGF2BP2, CD226, DAXX, SLC12A3, POLD3, MIR378A, TRPV4, MTHFD2, NGB, MIR33A, DAB2, SIM2, STIL, PNPLA2, CD68, MIR32, SLCO1B3, ITGAM, RENBP, DROSHA, ALKBH3, MIR130A, HOXA11-AS, OBP2A, CCR6, GMNN, CLIC1, HOXB9, EGFL7, CKS2, ESRP1, NANOGP8, KMT5A, KLK10, ATP7A, MAGEC2, CHRNA5, CHRNA4, TLX1, HOXA@, FBLIM1, HOXA10, TRBC1, STYK1, EPB41L3, RNASE1, PPP1R1A, SMYD2, JMJD6, MIR302A, SIGMAR1, S100A10, ANGPT1, MIR23B, MORC3, CSF3R, MIR216A, SEC14L2, CSE1L, PADI4, MIR19B1, AQP1, TDP1, MIR199A1, RPS6KA1, CRMP1, MIR188, PRPF31, RORC, BAD, MYOF, SOX11, CARM1, NET1, TMEM132D, ACR, CA12, HM13, PEG3, ACTG1, SNHG16, EREG, TNFSF14, PER1, FADD, TNFRSF18, CAD, ALKBH1, SPRY4-IT1, ROMO1, CALB2, CALCR, TIMELESS, ELF3, MBD4, MIR874, PDGFD, MIR708, ARTN, TERF1, MIR744, PDE5A, ESRRA, USP14, BTG2, MLANA, STARD13, LINC02605, UNG, VTN, UBE2N, FGF13, ZAP70, RBPJ, RIOX2, TYR, LDLR, FGF4, ETS2, TTF1, TRAF2, GLIS2, SPZ1, PC, TPO, LTA, KAT8, MYCBPAP, ETV5, LUM, STC2, CLDN6, TREM1, TP53I3, DSG3, TRAF4, DNASE1, GNA12, IKBKE, MFN2, TCF21, TNFAIP8L2, KRT7, MIR608, ATG5, KRT8, CAMP, MIR483, SERPINB5, RAB8A, SHCBP1, SNHG6, SREBF1, HBEGF, TSPAN1, PEAK1, NR1H4, SSTR2, IL12A, SNHG20, MEFV, STK33, VASH2, RBM5, TBX2, SLC25A3, MIR503, TAP1, DYRK1A, DLEC1, BIRC7, LGMN, CDX1, CBR1, TESC, BANP, GRHL2, SNORD14B, COP1, PAH, RETREG1, PA2G4, DDIT4, PAF1, RUNX1T1, TRIM44, PLA2G2A, PPP1R12C, SNORD14E, MPPE1, SNORD14D, SNORD14C, CENPA, PSEN1, FOXD2-AS1, WRAP53, USP44, IGFBP4, GATAD2B, CD247, IRF8, MTA3, CD79A, EIF5A2, CAMKMT, FER1L4, MARK4, ABCB4, ID4, TWSG1, TP73-AS1, PFN1, CD86, SULF2, SEPTIN4, CDKN2D, IL17RB, PITX1, PRLR, SNORD35B, ANTXR1, NLRC5, CDH17, MAP1LC3B, CDC6, VSIR, RBM38, KRIT1, PLOD2, SLC39A4, DEPDC1, MMP26, S100A11, NANS, OLFM4, PER3, MAP3K14, TF, GFER, GGT1, TCF3, EEF1A1, XPR1, TBX5, GCLC, SLC9A3R2, AIM2, RGS6, HDAC4, GNAQ, NUAK1, SS18, KIF14, PDCD6, HUWE1, SPTBN1, DMD, PSME3, STUB1, SOX10, NOD1, RAPGEF3, DEFB1, SEMA3C, TGFB2, GBA, GATA4, FZD1, VCAM1, FLII, VIPR1, WAS, WNT11, FHL2, FPR2, MZF1, U2AF1, ZNF217, FGF23, FCGR1A, FUT1, CRISP2, TRIM24, FANCC, FANCA, SPARCL1, TPM1, ULK1, DYRK2, OGT, EXT1, KHSRP, FBL, TLR1, ERCC6, TNFRSF14, PROCR, CXCL13, CHD4, SLU7, SPDEF, LRIT1, ROBO1, SNORD15A, GREM1, HAVCR1, STEAP1, SND1, TRIM27, HLA-B, RBP1, SENP1, RBL2, RBBP8, KDM5A, ERVW-1, KCNIP3, RAP1GDS1, GAL, RAD51D, RAD21, WT1-AS, ZMYND10, UBR5, TRPV2, LSR, BCL11A, UQCRFS1, FXYD5, SLC39A6, CRYAB, PATZ1, SDHC, DDT, SLC6A8, DAG1, PLK2, SLC5A2, CD55, SLC2A3, PGRMC1, SKP1, BRD8, SDS, WWP1, GTF2H4, GUSB, ICMT, PDAP1, GYPA, ATF5, H2AZ1, CCL4, SMG1, PEG10, TSPAN31, ATG4B, ARC, EGLN2, CRTC1, HAS2, BTF3P11, PTOV1, PRB2, MED19, NME1-NME2, CCAT2, ARF6, BATF2, MIR30D, INPPL1, BCL2L1, BTLA, HOXA-AS2, AZGP1, ROR2, MIR1247, LDHB, MNAT1, LPL, HEPACAM, ADAM8, NFATC1, NR3C2, SIK1B, MFGE8, BID, GHET1, BGLAP, MIR196B, KIF2A, MYCL, MARCHF8, ITGA2, NPAS2, ING2, TNFRSF13C, MIR29C, APAF1, APOB, LINC00460, MIR342, ABCA1, KRT18, MIR199A2, EGLN3, MIR425, MIR423, SSX2B, BST2, LINC00673, IRF1, PRSS55, MIR4435-2HG, NELL1, MIR185, MIR381, CMPK2, LETM1, LMO1, ARAF, MAT2A, MSX1, LBR, TINCR, DHCR24, MIR490, DES, SYTL2, CAP1, MCRS1, SMN1, CENPF, BTBD8, SPA17, SLC22A1, MBD3, HEXIM1, DUOX1, GRB7, MIF, SNHG15, CPQ, SMN2, CHD1, ANP32B, GLRX3, CGA, NCOA2, IRF3, MIR500A, TUBA1B, PRSS3, PDX1, NFIB, CDC25A, GGTLC5P, MED12, DPT, ST13, DPYSL3, MIR590, EIF3E, TEX11, GNA11, CD79B, NFKBIA, WTAP, PRDX6, KRT17, DHX33, GLUL, DOK1, DOCK1, HDAC5, FLOT1, NSD3, CYP2W1, DLD, DLEU1, MIR519D, ABCC4, SPAM1, PSMD14, TNK2, PRKCD, KNG1, SPOCK1, SRI, LINC00273, PARP2, PRKCZ, SAGE1, SMPD3, DDC, HDAC7, RSF1, ERO1A, CDK19, EIF6, SCT, CTBP2, UBE2S, PLA2R1, VASH1, IGHV3-69-1, CBX3, SDC2, ALOX12, COL1A1, COPE, MIR328, CTSK, ASCL1, ICOS, PTENP1, NISCH, SFPQ, MOS, PHF8, CSTA, AATF, CRH, DDX58, ITPR3, CRYGD, CRY2, CBX5, TARDBP, AQP3, CRKL, MT1A, IBTK, RNF2, HDAC2, WWC1, PHLPP1, MIR30B, SAI1, NUPR1, MTRR, RNH1, INTS6, GSTA1, AIF1, SLC19A1, CDC37, ALDH1L1, SLC2A5, NEU3, KIR2DS1, HSD17B7, NECTIN1, DTL, FOXO4, SLC6A2, VTA1, SLC6A4, PTPRJ, TDP2, GIPC1, PTPN13, MAP3K2, MIR383, NLK, BRINP1, CMPK1, ERAP1, NCR3LG1, DACH1, MIR374A, KIF2C, STOML2, RARRES1, KLK14, DNAJB4, MIRLET7C, MMP17, RIPK3, MIRLET7B, GLIPR1, ATOH1, NMU, HAGLR, HMGB2, BCAR4, MMP12, MLLT11, BTG3, KCNK9, PRDX3, MIR372, CD33, A2M, TIGAR, BCAM, IRS2, LYN, TM7SF2, NNT-AS1, IL12B, PGK1, DENR, ZC3H12A, PIAS1, DDR2, CCN3, PFKM, PIK3R3, CPEB4, GEMIN2, NR4A2, BMP7, GSTO2, SETD7, PRAP1, EIF3H, CXCR5, ACP1, PPARGC1B, ELF4, IER3, MARK2, TGFB3, GC, KSR1, GGH, EPHA4, THOP1, THPO, EPHB1, THRB, GATA1, LRRC32, TIMP4, HMGN5, EPS8, ACVR1, TNFRSF25, NECTIN4, LINC-ROR, NUAK2, IRAIN, PAX1, FXN, CCDC54, PCGF2, CNTN3, ZNF35, LMNB1, MIR155HG, XRCC4, LGALS4, TMEM54, VEGFD, XDH, CCEPR, WNT7A, FOXF1, MTG1, SCGB3A1, HTRA3, IGFBP5, IGFBP1, PANDAR, TYK2, SOX7, ACSL4, ACAT1, AGAP2, TRAF3, PDE4A, ZNRF3, OLR1, LOXL4, FBN1, TRPC6, CDR3, HOPX, FXR1, USP5, KISS1R, FDXR, SEMA3B, FZD5, CCNA1, NAA25, GGT2, MB, CCNA2, POU2F1, CLSPN, FKBPL, FEZF1-AS1, TEP1, SMURF1, ECT2, POLB, MIR454, TDGF1P3, OPN1SW, INPP5D, HSPA2, ADGRG1, GGTLC4P, TRB, RGN, MAPKAPK2, CLDN2, LPAR1, FANCM, MIR758, TCF7, ROBO3, APCDD1, USP28, PREX1, WASF1, BCYRN1, SCAF11, GGTLC3, HACE1, HULC, KDM2A, LOC102724197, CTNNA1, BMS1, ARHGEF5, MIR95, MIR30E, SSX1, FDPS, TRIO, MIR592, H3-3A, GNRHR, CTNND2, KRT8P3, SMC1A, SRL, PADI2, CTSZ, MIR331, PARK7, MPL, TRPS1, GALNT6, ECD, ALDH3A1, AKAP13, SETDB1, FCGR2A, ME1, MIAT, XCL1, DLG5, PIM3, TSPY1, NR4A3, SELPLG, MLXIP, SYCE1L, S1PR1, KDM4A, MIR92B, MT1B, CSNK2A2, HBB, SLC35A2, ROCK2, CGB8, CSNK1E, MIR27B, RXRA, LGALS8, TRAM1, FOXE1, CSHL1, SLC25A5, CABIN1, EIF2AK3, CSH2, CSH1, FLNB, LIFR, UTRN, MMD, SELENOF, HAS1, NAPSA, ADAMTS1, ANOS1, H3-3B, SERPINB4, SERPINB3, PLIN2, CST1, GJB2, MPRIP, DSPP, LINC01638, STAB1, JARID2, XPA, MAX, ZIC1, SALL2, FGF8, MCC, FBXW11, SAA1, SYNE1, TRIP13, DUSP5, FAM107A, ESM1, FBLN1, NR5A1, LUCAT1, AKR1C1, ADAM23, GFI1, SPRY2, DDB2, TLE1, TMBIM6, DCX, TEAD4, ERCC3, DCK, EIF1AX, VAMP8, TSPAN7, MIR382, DAPK3, TDGF1, POLQ, ETFA, RNASET2, G3BP1, USO1, MIR433, ACVRL1, GPX2, MICB, SON, VAV3, KLLN, MGP, NXF1, MIR202, C20orf181, TRPA1, KLRC1, MIR193B, DHX9, CXCL9, CDK5R1, UBD, GRK5, GDF2, MIR485, PRDX4, TM4SF5, MIR940, MIR675, MIR498, KIR3DL2, APLNR, CISD2, BLACAT1, DYRK1B, TAGLN2, CXCL3, KCNK3, APOBEC3A_B, EFNA1, LILRB4, PLA2G6, MMP15, FABP4, GSPT1, EYA2, WWP2, MIR339, KLRD1, LCP1, BPTF, PRDM5, PTPRT, EEF1B2P2, KAT7, ZBED1, RPS19, FYN, MIR504, FRAT1, MADD, RASGRP1, E2F2, RASSF10, ACTR2, SART1, MEIS1, API5, TROAP, RGS5, G6PC, SIAH2, BANCR, LTBR, KCNQ1, TP53BP2, HGS, BCL2L10, MMP10, ERP29, CYP2J2, RAB40B, RBFOX2, RYBP, RAG1, LINC-PINT, ENPP1, UCHL5, DDX41, LYPD4, PRRX2, SOX2-OT, LIMA1, CISD1, NECTIN2, PTPRZ1, SCLY, CHRM3, PF4, PLD2, PRR11, SPPL3, PPIL1, SRGN, IL34, RAB11FIP1, SKA1, SERPINH1, CHGB, USP17L2, VANGL1, SERPINA5, CMAS, TET3, FLCN, DOT1L, PCNT, MIRLET7E, MIRLET7D, ECRG4, TPP1, HLA-E, MIEN1, NOP2, DNAJB7, MINDY4, PCYT1A, IRAK4, CKLF, CPA4, IL7R, OCA2, CLEC1B, PDGFA, IMMP2L, RTL1, PTMA, HNRNPU, NSUN5, HOXA1, NOX5, BHLHE41, NDRG4, H19, IRAK1, TRPM4, HYAL1, PLA2G4A, PCSK9, RICTOR, WDR77, MAPK9, CHDH, NEIL2, NEFL, LAMTOR1, SLC52A1, IRF2, NPR2, FOXK1, HOXD@, CDH11, BRF2, CD109, PLAGL2, CAPNS1, IL15RA, FFAR4, PTGER4, PNP, PLCB2, CMTM3, OTUB1, HOXA5, NTHL1, NFATC2, LRRC15, FNDC3B, CETN1, HAND2-AS1, HOXA13, NRF1, PSMD4, ANLN, SUV39H2, NDN, CGB3, CDH2, CDH3, MIRLET7I, MUC17, RAD18, HSD17B1, MTBP, GLS2, KLHL1, SOSTDC1, HCAR1, BHLHE22, TMPRSS6, CABLES1, TOX3, MASTL, COL11A1, DLL1, ENTPD5, LETMD1, RFX1, RTN4, GGTLC1, PTPN5, ARHGAP1, ARL11, KIF15, PPP1R9B, CLIC4, BTG1, PELP1, SIGLEC7, MTUS1, SAT2, RORA, FBXO8, CDCA5, PCSK6, IL3RA, UCN3, MIR181C, CPT1A, HELLS, AGO1, BCHE, IGSF1, MIR187, MTX1, SNHG12, RASSF6, ZBTB32, CPE, XPO5, ACCS, ITK, MTHFD1, PMEPA1, MIR196A2, MYLIP, BRD7, RPS6KA2, PRSS50, AMOT, SPINK7, RBP4, OPA1, CARD10, MIR134, CNGB1, CGB5, PCBP1, SLC5A8, RBBP6, KIDINS220, C1GALT1, ASPH, ITGA3, NT5C1A, REV3L, CNR1, IL2RB, PLA2G15, ITGB2, PAK5, IMMP1L, HFM1, TAFA4, SMPX, MVD, PAX6, PPA1, KDM2B, COL1A2, ARNTL, IL6R, OPCML, RPS6, BTF3, CBFA2T3, ASAP2, TSPY10, EMP2, CDK15, CAV2, RTN4R, NOLC1, ENPEP, INTS2, CCN5, SPANXA2, LOC100288966, EMP3, OR2AG1, ADARB1, CCNG2, BCORL1, FKBP10, CCNF, RINT1, MIR802, BRCA3, SAV1, TP53INP2, ZNF569, S100A16, CCT, EFNB2, PDCD5, ASPRV1, CCNE2, SMC3, HEATR6, MIR873, ELK1, BTRC, ELF5, FUBP1, BUB3, TRAP, ZNF398, NBAT1, CCNB2, CHD8, CD1A, KIF18B, MIR944, CARD9, CBS, MIR543, PKD2L1, NCOA5, TSPAN12, TPPP2, MIR1207, ANP32A, TP53COR1, FGF3, MAFK, KAT6A, AFAP1L2, MLLT10, MAP1LC3A, C5AR1, LRRC3B, YEATS4, CARD11, CA8, FBP1, PHF6, RBM10, KDM5C, NUS1, TRRAP, AXIN1, BNIP3L, ITCH, PRNCR1, TPTEP2-CSNK1E, BSND, ABL2, CERNA3, FOXP2, FLT3LG, NAPRT, SERPINA3, H3P47, FLG, SIRT1-AS, VRK1, FOXF2, RN7SL263P, WNT3, PYGO2, WNT10B, ZNF501, NUDCD1, YWHAE, FGF10, ABCA4, FGF9, TNS4, C4BPA, JAM3, SCHLAP1, H3P41, NR2F6, OSCP1, IQGAP3, EHMT1, ACO2, TBL1XR1, ACTA2, NEIL1, HYAL2, ADIPOR2, ACTG2, DHRS11, FCRL5, ADAM15, MMP28, EPHB6, MAPKAP1, EPHB3, BIK, CASP2, ASPSCR1, BRD9, EPHA7, HSD17B6, PSMG1, LPCAT1, H3P12, SHARPIN, SPRY4, PGR-AS1, BMPR1A, FIP1L1, EZH1, TXNDC5, TWIST2, ZNF436, TSGA10, FOXN1, ULBP2, BMP6, ACHE, CLEC12A, BMP1, CALD1, ESRP2, CAMK4, FALEC, RUVBL1, SCYL1, IQSEC1, DNLZ, GTF2H5, PLAC8, MIR371A, CIRBP, CBX1, IGF2-AS, NUSAP1, SMIM10L2A, TMED10, MIR367, GASAL1, CLCN3, APH1A, NDUFA13, VANGL2, DESI2, AHSG, NUS1P3, CLN3, IGK, SYCP3, ADAMTS13, CYP2A13, CTAG2, EHD2, ATF1, SPANXA1, DBF4, FASTK, PAPOLA, FZR1, RAD51AP1, CELF1, ARID4B, ZNF44, MPC1, DLL3, RASD1, PTRH2, ATP5F1B, NFAT5, PTGES3, ALDH7A1, CHL1, MED15, CHRNA3, HSD17B13, NCKIPSD, NEK6, SUMO1P3, ATP2A3, ATRAID, ADAM28, MRPS30, LYVE1, CENPW, HHLA2, CORO1A, CYP3A7, RND3, CST6, LPIN1, AMPD1, EHF, FBXO4, CABYR, DGCR5, PTPN22, CPT2, USP24, AQP4, ZNF629, MAU2, CRHR1, PART1, SIRT5, ARIH1, CIZ1, IL17RA, SGK3, TNFRSF13B, DAPK2, CORO1C, ARL2BP, MIR219A1, MIR154, NOX1, CMM, AMFR, LZTS1, ASCL2, FZD10, RACGAP1, FILIP1L, ARSB, CNTN1, MIR302B, COL4A2, TRBV7-9, EIF2AK4, TRBV16, OIP5, PHLDA1, ARNT, CILK1, NLRP1, MORC2, HTRA2, ATF6, RAB3GAP1, MIR7-2, CTBP1, CP, TNIK, NANOS2, ZAR1, POTED, MIR638, MDC1, AJAP1, MIR625, KMT2E, EIF4A3, UNC45A, RB1CC1, MIR589, GINS1, ZNF395, ST6GALNAC1, TLK1, MIR574, APCS, MIR551B, MIR421, AGK, MIR539, USP15, BTBD7, CCDC88A, RBX1, THOC1, FERMT1, CDC27, PPM1F, CFC1, DDX43, RNF20, CD9, EDA, LHX2, ADCYAP1R1, LIPG, RECQL5, CIAPIN1, IDO2, DVL1, NCR1, QKI, TSPY3, MAP4K4, RASAL2, FAM20C, BAK1, EEF1E1, MUC5B, RAB3D, ADGRB1, CYTIP, BCCIP, PRMT8, GKN1, TSC22D3, KLK15, GPRC5D, AKR1C2, SAMD9, HCA1, SLC9A6, ZNF763, LY6K, CRTAP, OTUD4, DDX56, UGT1A9, MYBBP1A, DDX17, UGT1A10, TUSC7, DGCR8, LAMTOR5, WNT4, HTATIP2, ERRFI1, SCARA5, SCAI, AP2A1, DCUN1D1, TRIM59, GNLY, SORBS1, TXNRD2, BCL6B, ASPN, SMC4, PGPEP1, MCM10, EDIL3, DNAH8, LGR4, SMIM10L2B, CDH5, DNA2, MIR505, OPTN, BCAP31, MIR501, TOB1, LARP6, ZNF197, CDH6, FANCI, RIF1, DLX2, MTPAP, SLFN12, ADRB3, MKS1, CASZ1, GRK2, CYB5R3, TP53INP1, LIG1, MAGEA4, POLH, ATXN1, MAP2K2, HLA-F, FRZB, THBS4, SCN1A, SLC22A2, KLF10, P2RY2, TIE1, PTGER2, GAS1, PLAGL1, RPL22, SYP, TRO, UBE2K, FBXW4, SSTR3, PMS1, FUCA1, TRAF1, PKD1, PHLDA2, UPF1, RRAD, QSOX1, DRG1, MUC3A, PARN, KAT2A, IRF6, FRK, TNFSF4, GRM1, PAPPA, MAPK12, MAPK6, SAT1, SDHA, ITPR1, TTR, GLDC, NELL2, NEO1, SNRPN, THAS, RFC1, PTMAP4, SGCB, CCL22, MAT1A, TNFAIP2, STAT4, INS, KRT5, GML, PIGR, SFTPD, MKNK2, CCL3, MGAT5, NPR1, PRSS8, TPD52L2, MEF2C, RPN2, KIF11, MEF2D, NOVA1, INHBA, HLA-DPB1, MEIS2, CNOT3, MAP3K1, GAD1, RBM4, RAP1GAP, RPL36A, MMP19, KCNMA1, TLN1, SEC62, GZMA, OPRD1, H1-0, GAD2, PPP2R1B, TLR5, NR2E1, KRT14, TPR, AFDN, TSPAN8, PLXNB1, PRPS1, MCM5, MAP3K11, FUT8, IARS1, PSMB8, MUC6, MAP3K5, TRIM37, GDF1, HPR, NAP1L1, SUMO1, PLEK, PTPRK, CYP4F3, UCK2, PLCL1, GHRHR, RAC2, MYH2, TFCP2, GADD45B, USP4, FMR1, PRKACG, TRG, ENPP2, PTPRD, PDK4, SELL, RAB27A, SCGB1A1, MSTN, SEMA3F, HSD11B1, TFAP2B, PRKCI, IFNA2, IFN1@, IRF7, GJB1, PF4V1, PTPRA, UGT2B7, LRP5, HNRNPA2B1, TCF12, POLR2E, PPP1CA, S100A2, PCDH8, TBL1X, LAMP1, PGC, RAB1A, PRKCE, PTPN3, NAB2, ITGA9, TM4SF1, PENK, HPN, LOXL1, SIPA1, RAC3, CSMD1, CCL28, SIVA1, INHA, CLCA2, PYCR1, CERS4, ETV7, UGT1A6, DDX21, PDP1, NCOR1, SAA2, RAB37, MICAL2, CAPN6, EI24, LXN, SLC33A1, INPP4A, RAB39A, SUV39H1, DNAAF4, EFNA2, SMARCC1, RIN1, PPP2R1A, CHAC1, PPP2CA, HACD1, SCN10A, DUSP4, KIF20B, TNS3, RBM39, CREBRF, IRX2, AHNAK, CPEB1, NCOR2, CPP, NQO2, SPAG6, KLB, NODAL, DTYMK, CTSC, TCN1, BCL2L2, ISYNA1, PEBP4, COMMD1, CDCA2, UGT1A8, PAQR3, UGT1A4, OGFR, ACTBL2, NFE2L3, ACKR4, CCL4L2, DERL1, MACROH2A1, BCKDHB, MAP3K13, PKD2, RNF168, CBFB, KANK1, FNDC5, TARBP2, SOX30, E2F6, JAZF1, DPYSL5, IREB2, SARS1, TAPBP, NFE2, TAP2, CAVIN1, CHM, HABP2, GCNT3, PSMA1, HNRNPL, BAGE, SLC13A5, RHOBTB2, CERS6, IFNL1, IL4I1, ASPM, ATP7B, NCR3, S1PR2, CNMD, DEPTOR, IFNL3, TRIM16, TAOK2, IL25, CNTN2, GCLM, POU3F3, IRF5, SLC25A1, TCEAL1, HNRNPD, CCNY, SIK2, CD58, SPAG5, CHST3, ZNF423, INSM1, NLRC3, MLKL, AZIN1, ARID2, PGAM5, MTA2, FRTS1, KIF23, RHOV, NHLH1, DLX6-AS1, DACT2, TMED10P1, DNAJB1, SLC18A2, EEF1A2, PKP2, PIKFYVE, HAND2, INSRR, NOG, ADA2, SGCG, CENPH, SAFB, LRP1B, SHC3, PTGER3, GLUD1, ATP6V0C, BCO1, GLUD2, EEF1AKNMT, PTPN12, NPRL2, RABL3, RAPH1, FHL5, TRIP10, IL31RA, HOXB4, PBX3, ATAD1, MIR503HG, PHF5A, PDZK1IP1, SEC23B, BATF3, CBX2, BEX2, TREX1, IGFBP6, USP18, PKN1, RMI1, ATOH8, TSHZ1, ENOSF1, CHP1, MCM8, RCC2, SRSF2, HPD, SYVN1, MAML2, PROK1, AKT1S1, GDF11, HES6, PAK2, ING5, CREB3, UBA2, CALU, SNORA73A, HOXD3, SDC4, ACOT7, IL18BP, PPP3R1, STK38, SLC25A21, LMLN, SRM, TSPYL5, IGHG3, DCLK3, PI4K2A, SREBF2, CDH4, IL1R1, SRD5A2, PAFAH1B1, IGL, HOXD9, DMP1, FAM83A, SPTAN1, BRMS1L, NBR2, P4HA1, SOX5, DIO3, GTF2H3, CAND1, SLC25A20, KLF2, CDT1, ENPP3, IFIT3, USE1, IRF9, SLC38A1, IFIT1, ZBP1, CDCA3, WNT5B, GTF2H2, WDHD1, ZFP91, PIAS3, UTS2R, WFDC2, SPAG11B, ASXL3, IFITM3, GPR17, SPON2, ADCY10, CYBB, PPT1, TMPRSS13, MAF1, PFN2, ZC4H2, SFRP5, PPP1R1B, PDCD2, URGCP, KDM4D, PFKP, IFI16, HORMAD1, DUSP10, FMNL1, WNT10A, MAD2L2, PDGFB, HDAC10, ENAH, KLK8, AP5M1, ADGRE5, KATNB1, HAX1, PTTG1IP, SELENOP, CEP70, GOT2, SERPING1, AGPAT2, NUCB2, CCL7, NSUN2, ALKBH5, RNF144A, CAPG, CPT1C, RIOX1, SOHLH2, IL11RA, FAN1, SARS2, CHDM, ALKBH2, FOXK2, NUMA1, NUP88, PIGA, E2F8, ZNF750, TRIM14, SLC26A3, DCD, HOXC6, DPYSL2, PARPBP, BMX, DCBLD2, YTHDF2, MAGI2, DYNLL2, IMPA1, GSC, CAPN2, DYM, VGLL4, CTAA1, ERCC6L, ESPL1, NOTCH4, SMARCE1, METTL3, HT, BRI3BP, SMO, ADAMTS5, GATA5, DSG2, PTGR1, FOXR2, SETD1A, AMER1, DPP8, VPS37A, DSC3, CCDC26, ST7L, LRIG2, CARF, PARP3, PDGFC, SHQ1, MYOCD, KLF9, ORAI3, HOXC10, PTBP3, P2RX4, CDK3, CASP8AP2, IL3, ATAD3A, IL2RG, CD81, OXA1L, GGNBP2, PACC1, ASXL2, NEK9, SSAV1, PSPC1, CTSE, MAP2K5, DPP9, SRSF6, CREB3L1, SRPK2, BAALC, OPN4, SERPINE2, SLAMF6, MOCOS, SERPINB6, ATG16L1, TOX4, DDX46, WDFY2, PHF1, UHRF2, PTPMT1, CD52, SSX4, CPEB3, KDM8, BTC, SSTR5, SLC22A18, HELQ, CDCA8, SLC46A1, PUF60, OTX2, TNFSF15, GPR35, OVOL1, DPEP1, CTRL, GEN1, MYO6, HHIP, ST8SIA2, MIR938, MIR216B, FTH1, MIR301B, SLC14A2, COPS6, MIR888, TRPC4, NRIP1, TRPC1, CHAF1B, MIR300, CCL27, SNHG8, ARMC8, USP11, FBLN2, HPP1, NAA10, ASF1A, MIR766, COL4A1, FANCG, RGPD2, MAPT, MIR942, TSN, BRAP, MIR885, PNN, FCN2, DUX4, NUP214, IGHV3OR16-7, SLAMF7, IGHV3-52, HTT, MUC3B, DAB1, LAIR1, PDHX, CUL5, PTP4A2, ZNF667-AS1, COL6A3, AD5, MIR760, MIR889, FCGR1B, COL5A2, IFT88, CLLS2, ARHGAP35, GPR68, FANCB, OVOL2, CUL3, MIR628, HYAL3, MIR618, MIR616, F8, SHOX2, PLA2G10, MIR613, SMCP, SRPX, TPI1, ADAM11, MDH1, MIR584, PLK3, B4GALT1, MIR564, TPBG, MED1, MIR411, MIR33B, ADH4, FZD2, RBL1, HNRNPA1P10, EYA1, MIR622, FAAH, OIP5-AS1, OLA1, MAS1, FZD6, MATK, MAZ, SLC2A4, UBE2T, OPRPN, SCAF1, METAP2, ADCYAP1, RCVRN, SI, HSPH1, CCR9, BLNK, TMOD4, CASC8, KRT16, IL22RA1, RBP2, NTN4, MIG7, RAD54B, MCM3, MIR634, MIR1258, SMAD5, MIR1270, WIPF1, CD5, HBP1, HDC, FOXG1, FKBP2, FOSL2, SKI, WNT6, ACACB, U2AF1L5, INTS1, WNT2B, WNT9A, AK6, XBP1P1, LNCNEF, RPA1, FPR1, EHMT2, CD3D, FGR, TES, SKIL, LTB, YES1, LINC02210-CRHR1, VWA5A, MIR1297, LNPEP, LIMK1, USF1, RNU1-4, LIMK2, H3P42, FMOD, AADAC, H3P17, H3P13, TINF2, VCL, ABCE1, UPP1, MNS16A, CD6, ERVK-32, ROM1, LOC108004545, NDRG3, LIPE, LLGL2, UGT2B17, CFH, CKAP2, CPM, HGD, WDR48, WSB1, LTBP3, FRA6E, TNFRSF21, PCDH17, FRA7G, MAGI2-AS3, LEPQTL1, SRPX2, L3MBTL1, MIR466, MIR2909, FES, ST8SIA4, CYP27A1, FER, SLC31A1, COMP, POLG, CBX8, CD1B, RGS1, C1QL1, POU5F1B, HRX, FGL2, RPL5, CBR3-AS1, IL17B, DSCAM-AS1, ZNF143, HGFAC, NSG1, ACO1, LAMP3, ZIC3, POLR2A, SH2D1A, ERVK-20, UBB, MIR4443, APPL1, ZBTB16, LAMC1, TRIM25, RAB4B-EGLN2, BCL2L2-PABPN1, ACP5, CD1C, CAPRIN1, DKK2, RAB22A, LINC00665, JTB, ZYX, PKN3, MDH2, CUL1, SDF4, TGM3, RRBP1, MT2A, RREB1, APOA4, TGIF1, TGFBR3, APOBEC1, APOC3, CLC, GBX2, TGFB1I1, EMP1, MIR199B, MIR198, KAT6B, RAD51B, ELN, FXYD3, SCRIB, RTKN, RAB31, GCK, MACF1, RAD23B, CCN6, CLCA1, CSK, ADAMTS9, ALOX15B, MIR98, AGFG2, AMCN, MIR7-3, MYO1B, CD164, MIR7-1, RIPK2, RAG2, PBOV1, KCNA5, AMHR2, CDH23, JAG2, EPHA8, AMY1A, AMY1B, AMY1C, MT1F, FGF18, STOM, SLC29A1, TCFL5, MT1JP, MIR16-1, RHOB, PPID, SEMA5A, ARHGEF28, PLA1A, EIF2S1, RHBDF1, SIRT4, SORT1, LRRC26, ANGPTL1, COTL1, CSNK2A1, CCL4L1, TNFAIP8L3, FBRS, EGR3, TBPL2, ADNP, DNAJA3, USP6, USP2, USP10, USP8, PPP1R12A, NCSTN, NMI, ASPG, GSDMB, EBP, CTNNBIP1, RNF8, CLDN18, RAD9A, NT5C3A, ITGAL, ITGAE, HSP90AA2P, MIR127, ITGA7, MIR124-2, MIR124-1, SERPINC1, BFAR, MGAM, MYH9, MIRLET7A3, ERAP2, TLR8, TFAP2C, SELENBP1, LIMD1, KPNA7, HSP90AB1, ATOX1, MLST8, RAB27B, CLK1, RPS15A, PRDM16, MELTF, PLXDC1, MIR484, PIR, KIFC1, HCC, RAB38, GAB1, MIR509-1, MIR508, CDK10, MIR506, MIR502, CRY1, MIR362, SCGB2A1, SOX8, MIR432, MIR493, TMEFF2, RPS3, HLA-DQA1, CIITA, NOP14, ADGRE2, MID1, HCRT, PARP4, POTEM, FLVCR1-DT, SH3KBP1, DNMT3L, SMARCA5, SERTAD1, IRS4, MEF2A, CDC42BPA, CERS2, SEMA7A, KIF4A, CCNG1, SPAG11A, XAGE1A, PPFIA1, BRD1, EVX1, AFAP1, XAGE1B, MMP23B, NOP53, IKBKG, IFITM1, NORAD, EFEMP2, BACH2, H3P16, ZNRD1, ITIH5, CCR3, MIR422A, MIR379, TM4SF4, MLLT3, URI1, ZMYND8, MBL3P, RAN, PLXNA2, TNN, RAP1B, EIF3C, RPS7, MIR370, MIR369, MIR330, EYA4, DERL2, RAP2B, CCR1, IL21R, MIR302C, KIR3DS1, MPST, HLA-DQB1, LDOC1, HCLS1, TP53AIP1, MIR31HG, CMKLR1, PDSS2, DUOX2, SOST, POTEKP, HSPA8, KLK2, EXOSC5, KNL1, PPP1R3A, PPM1A, POU4F1, AS3MT, RHBDD2, PAK6, GPRC5C, BEX4, ZMIZ1, CD48, PELI1, PARD3, CD177, FMN2, ERAS, CD5L, SLURP1, CD8B, APOM, PPP2R5E, RHOJ, ERBIN, SPC25, TCEAL7, STK31, NDUFA4L2, PPP2R5C, PPP2R2C, PPIB, MFF, NPY4R, PRMT2, DEFB103B, POU4F2, ABHD6, PPM1B, SCARB1, NSFL1C, RALGAPB, LRRC8A, RNF17, SUCNR1, DUSP22, PPP1R8, KLHL7, SLC2A9, UQCRH, LRBA, KMT5B, ABHD5, MLXIPL, RALA, RALGDS, ATL1, LAP3, RANBP2, ARHGEF4, HLF, CCR8, ACKR2, G0S2, TLX3, TBX21, UBQLN1, MDFIC, PADI1, LINC00312, CNOT7, TFCP2L1, CNN1, PARVB, TMOD3, METTL9, SBDS, PTPRO, HLX, GTSE1, FOXA3, REV1, PYGB, SNX9, CRLF3, HMGCS2, RAB6A, RAB13, CHST15, TAOK3, DACT1, CKB, THEG, BPIFA1, TFDP3, PIPOX, MARCHF2, RAD17, GPN3, ERCC8, CHCHD2, HMBS, MNX1, CLEC2D, CTNNA3, RDX, SALL3, NAAA, PALD1, HSPB7, EIF2AK1, RHAG, CPB2, RLN1, RING1, RLN2, ATP2C1, MLH3, FOXD3, BEX3, CYFIP2, SNORD43, MYEOV, RGS17, TIMM13, CNNM4, SLC17A5, SEZ6L2, LHX6, RND1, CRCP, BMP10, COL7A1, FHOD1, CNR2, C1GALT1C1, ASAP1-IT1, RELB, KLF15, COL4A5, COL4A6, GIT1, DCPS, HIP1, RGS4, IGHV1-12, RFC3, RFC4, MAT2B, DESI1, STK39, PCSK1N, COL17A1, RPS6KA6, TNRC6A, HNMT, PTPRG, EAF2, DRAM1, MAP2K3, MOB1A, NAT10, RCBTB1, PNPO, MSTO1, PSPN, PROC, FANCL, PRODH, TMEM45A, HOXC8, EPN3, FKBP14, MARCHF1, PRPS2, CEBPE, PRS, ODAM, CMTM6, YTHDF1, SEMA4C, PRSS1, SLC29A3, MAPK13, PTPRF, HOXD8, SELENOS, DEPDC1B, PREP, PRF1, DHX32, OGDHL, ATF7IP, WDR11, UROD, VAC14, HIF1AN, TMEM127, CDC25B, CHD7, ASAP3, CDKN2AIP, PLXNA3, SOX6, PRKCH, TNFRSF19, HOXD10, ZNF331, TMEM176A, RELN, UHRF1BP1, TEX10, TENT5C, POLE3, PPIL3, GPR87, FGFRL1, PTGDS, AKR1C4, PTGFR, HOXA4, SIX4, STK26, LUC7L3, HNRNPH2, CHIT1, UIMC1, RAB23, HNRNPH1, PTPN2, GINS2, RTRAF, PTPN14, LYST, CYRIB, RAB14, H2BS1, CYCS, PSPH, PSMB5, PSAP, CELP, TRIT1, RNF111, MARCHF5, PSMA6, UGT1A3, PARP14, PSMA7, PSMB4, UGT1A5, TREM2, ING3, ROBO4, PCDH18, TMCO1, PRMT7, CEACAM4, RCC1, SLC38A2, PSMD7, PSME2, REXO1, MCU, PPM1H, APOD, TRIM23, MIR184, MTNR1A, AQP9, ITPKA, MIR197, APLP2, MYO5A, MT1L, ANXA13, ANXA4, ANXA3, MT1H, MIR24-1, ARF1, MIR181A2, ITGB6, RHOC, RHOG, ARRB1, ARRB2, ARSF, ASPA, ITGA4, ATIC, MIR101-1, MYH6, MYH11, MYL2, HOXB-AS3, KLHL31, ANK1, MT1G, MIR28, MIR345, ATXN3, CT45A1, DUXAP10, MLF1, AGTR2, MAP3K10, AHCY, PLF, LNCR1, PALM2AKAP2, KIF5B, KHK, MIR376C, MIR346, MIR337, AMPH, MNT, MPG, MPI, MIR323A, KCNJ11, ALDOA, KCNJ3, LINC00857, DEFB103A, TNFSF12-TNFSF13, AMBP, AMD1, AMELX, KARS1, CCSER1, LINC00668, AFM, CXCL17, SELENOH, SBF2-AS1, RASSF3, B4GALNT3, LAMA1, DYNAP, WDR62, ATP1A1, RSPO1, ZNF326, MIF-AS1, CAGE1, P2RY8, ISL1, TIPRL, KIF1A, PTF1A, NPNT, ZDHHC20, MSRB3, CADM2, VAMAS6, SPDYA, KDM1B, NFATC3, NFIC, LTO1, DDIAS, VWCE, ENKUR, FOLH1B, CLEC4D, HSR, NBL1, CYCSP38, FENDRR, GSEC, USP17L9P, LOC390714, SERPINA2, CSAG3, SAMD5, ATP12A, MYO10, SERP2, SNHG5, IL31, MIA3, ATP2A2, NAGA, NASP, ZACN, SKA2, LINC01193, ATP4A, ZFP57, HNRNPM, NANOS3, GOLGA6A, VWA2, RSPO2, TSPAN33, ARMH1, LINC01139, TFAP2E, MIR448, TLE5, SMTNL1, THORLNC, MIR3619, GAPLINC, LAMB3, LINC00958, HOTAIRM1, LINC01234, TTN-AS1, MFT2, ACTL6A, C8orf17, EGFR-AS1, LY75-CD302, P2RX5-TAX1BP3, BED, MIR3120, MIR3148, LAMA5, MIR761, ALL1, BCC1, NCRUPAR, ACYP2, MIR1290, MIR1908, MIR1236, MIR664A, MIR1291, MIR1275, H3C9P, WASHC1, MEF2B, PSC, LY75, HIF1A-AS1, GACAT3, H3P11, H3P28, LNCRNA-ATB, LIMS1, LOC112694756, LOC110283621, CNE-2, ABCA2, LLGL1, WSPAR, LOC105379528, AOC1, UPK3B, MYOSLID, ERICD, ERVK-18, PCAT2, LDHC, LOC102724334, CSAG2, LRP2, SAMMSON, LRPAP1, LSS, LTA4H, LSINCT5, NPY4R2, COMETT, PTCSC3, CYP3A7-CYP3A51P, MAG, MAGEA2, MIR18B, ME2, WASH6P, SFTPA1, FAM72B, KPNB1, H3P38, H3P37, MIR542, ADARB2, SCARNA22, MIR551A, MIR577, MIR605, MIR615, MIR629, ANXA8, ADH6, ADH7, SCFV, ADK, MNX1-AS1, MAP3K3, MIR487A, KLKP1, MIR520C, MIR520F, MGAT3, SCGB2A2, MIA2, MIR511, MIR489, AP2B1, ADH1A, MIR639, MIR650, MAP4, KIR2DS2, TSTD1, FAM83H-AS1, MIR297, MAGEA11, MAGEA12, MIR147B, MIR876, ADCY1, ADCY2, KTWS, MIR765, MAOB, MIR769, FAM72A, MIR652, MARK1, USP17L30, USP17L29, USP17L28, USP17L27, USP17L26, USP17L25, USP17L24, D2HGDH, MBP, MBS1, MC2R, MIR661, MIR660, NFIL3, SAMD9L, NLN, CACNA2D1, MED28, PFKFB2, PFDN5, PNPLA3, SLC19A3, SRCIN1, ZNRD1ASP, ZDHHC14, EGFL8, ACTL8, CCNL2, CA11, RAB1B, KIF18A, PREX2, FBXO11, MUS81, CDK14, TRPM3, DOCK5, PGD, CALML3, SCD5, ATAD5, ZNF671, ID3, AGBL2, PIP4K2C, METTL8, PHF2, MYH14, PITPNM3, PDHA1, NUF2, PDE3A, PCK2, ACSS1, ACRBP, SLX4, LCOR, MAP3K21, LZTS2, ZBED3, SARNP, CHCHD5, PDB1, PDC, ARID5B, EVA1A, PDE4B, TMUB1, ZRANB3, PDE4D, PDE7A, WDR54, CCDC8, RASSF4, SPRTN, CDCA7, MRO, HMCN1, RIOK1, FERMT3, FAM107B, TEX101, STEAP4, VEPH1, LCS1, RXFP1, NLRC4, CCNH, SELENOK, UBL5, PMM2, SENP2, PNOC, HECTD3, ELAC2, MIIP, PLS3, PLRG1, PCGEM1, TSPYL2, WFDC1, HSPA1L, ZNF410, DNAJA1, CCT6A, SCUBE2, METTL14, MAGEE1, PHRF1, ZBTB4, EP400, HSD11B2, PON3, MAVS, POU2F2, POU3F2, ARID1B, PERP, PLOD1, PARVG, NIBAN2, RHBDF2, GALNT14, FYCO1, ICAM2, EFHD2, RETREG2, DHX58, CARD14, NABP2, CUEDC2, CYREN, WNK2, PKP1, FOXN2, USP46, TNMD, TUT1, GINS3, MICAL1, ILRUN, CREB3L2, PDIA2, ATG3, CDH22, ZMAT3, PDLIM2, NCAPG, XYLT2, ADGRL4, FN3K, PCDH9, IL1F10, DIPK2A, WIPF2, KRT80, A2ML1, LINC00052, CMTM4, MGAT5B, EME1, ZNF582, IL12RB2, LINC00662, BCS1L, NONO, DTX3L, INPP1, SGO1, E2F7, PRICKLE1, MIB2, ILF3, ZBTB46, NEK7, SELENOM, PIP5KL1, ADHFE1, TAAR1, BLMH, ZFP42, CD200R1, TRIM71, ACVR1C, DIS3L2, NMS, CCDC80, FGD5, IGSF11, ADAMTS18, HIPK1, SLC25A43, CT83, C9orf72, LGI3, NFKBIE, TRIM65, CENPV, FBXO45, CRYGEP, GKN2, CRTC2, NLRP6, NKX3-2, BCAT1, PRAG1, MIER3, NID1, PARP15, NINJ1, NNAT, SLFN5, FSIP1, SLC35G1, MAGEB6, FMR1NB, SPAAR, TMEM74, LRATD2, ESCO2, PIGU, B4GALNT2, DPY30, CCDC34, UCN2, OTULIN, MLIP, LINC00473, FMNL3, CERS5, ACY3, ZG16B, YTHDC1, P2RY4, TIMD4, ZNF300, CCNQ, P2RY1, PHLDB2, WDR34, NAV3, TNKS1BP1, SLC45A3, NKD1, ALG2, BAGE4, RERG, RBM17, UBASH3B, ZNF382, RSPO3, LINC00467, CNDP1, LOXL3, PAX7, GLYATL1, CRB3, MARCHF9, DNTTIP1, MTFMT, JDP2, LRIG3, LARGE2, MMP21, PCAT4, BMPR1B, THEM4, BMPR2, LYPD1, RBP7, OGN, OMP, FOXP4, OPRL1, CLEC6A, ALPK2, SIX6, OMA1, EPB41L4A-AS1, OSBPL5, LMTK3, BPHL, OSBP, SLC52A3, PHF21B, CLDN11, BMS1P20, EPSTI1, TTYH2, HSPB8, FBXO22, MYCBP, ANXA10, MAP4K1, EPS15, TNFSF12, GALNS, GALNT2, ADAMTS6, EPHX2, RIOK3, TIA1, THRA, TNFRSF10D, TNFRSF10C, BVES, GSR, SRSF5, EPHA5, CDKL1, POLR3A, CD160, BTN3A1, CES2, HRK, SEMG1, MTF2, DDX20, PDXK, ITGA11, MKNK1, PDLIM4, NID2, STK16, LY6D, ETV2, CXCL11, U2AF2, MGAT4A, BRF1, EIF3B, EIF3D, EIF3F, SLC6A14, GALC, PDCD10, SEL1L, EED, CTNNAL1, CIT, SRSF7, TRA2B, SOCS2, CACNA1H, SLC27A3, PHOX2B, H3C7, H2AC11, USP13, WASL, EBNA1BP2, ST3GAL1, ST3GAL4, NOL3, TOMM34, KALRN, STARD3, EHD1, CYP4B1, GFPT1, SLC13A2, PAPSS1, GFRA1, TDG, PRPF4B, MTMR3, TLK2, GCHFR, ATE1, PRSS23, SFTPB, DLEU2, TSC22D1, GBP1, TRIOBP, TRIM31, RAPGEF4, ELK4, KLK11, CNTRL, VNN1, NUDT21, GCNT1, EIF2B5, DSTN, EIF2S2, RAB35, BUD31, MRAS, GABRA3, MTMR11, H2AC15, H2AC16, H2AC17, CLEC11A, PLXND1, TOGARAM1, SPART, KIF1B, H3C1, TTLL5, H3C4, ARHGAP26, ZC3H13, H3C3, H3C6, H3C11, H3C8, H3C12, H3C10, PPRC1, KDM4C, H3C2, MAPK8IP3, H2AC13, CDC14A, GFI1B, LARP1, TAF15, AKAP1, S100A12, ELL, FCAR, MKKS, TRPC5, SYNM, DVL1P1, ESS2, SIN3B, MCF2L, NBEAL2, PICALM, FAH, SALL1, FUT2, FAM168A, RCOR1, LARP4B, FABP1, TPM4, NCOA6, MYT1L, CCL11, TNR, TNNI3, ENC1, MMP23A, CD93, HAT1, DGKZ, TRAK1, RUFY3, DIS3, CCL17, TNNC1, AGPS, APOL1, FNDC3A, LMO4, GZMM, FCN3, CHSY1, LMTK2, MAP4K3, SCAP, SNW1, DOC2A, UXT, CSTB, SNHG3, CSTF2, PALLD, FAIM2, SPEN, STK38L, RAB21, DHX16, KIN, SCTR, IFI6, KLF11, MAST1, NINL, AKR7A3, RAE1, TRIM32, TOP2B, EGR2, CPSF4, FRAXB, CNKSR1, GLYAT, RABEPK, SOCS5, SDC3, STX6, CD96, TRIB1, ANGPTL7, CEP57, CTDSPL, OLIG2, ULK2, DLX3, DHRS2, GPLD1, HERPUD1, ALG3, RNF41, GPD2, GNAI2, SEMA3E, SPRY1, SPAG4, DHPS, DLX1, DIAPH1, GPR4, DIO1, APBA3, MRPL33, CHD1L, HMGB1P5, DUSP3, B3GNT3, CRISP3, SOX15, LANCL1, STXBP3, PDIA4, CARTPT, DLG1, DSP, DLG3, UBE4B, AURKC, FEZ1, DSG1, KNTC1, RBM6, TENM1, DNAJB6, RANBP9, DNASE2, SH2B3, STAR, DYNC1H1, RO60, ITPRID2, DOCK2, RHOBTB1, DOCK3, SNAP91, DMTF1, TELO2, RCE1, MRC2, CCS, GOLGA2, DPYS, HS3ST1, HS3ST2, STAT2, DPP3, SRP72, DLX5, SLK, WASF2, LPAR6, SNPH, STARD8, ATP6AP2, TOX, DLX4, PLXNC1, DSC2, SCRN1, RASSF2, DLGAP5, SQLE, DSC1, DNM1, SRD5A1, ARL4C, ARPC2, PPIF, DUSP7, DUSP9, CYP26A1, EEF1D, OSMR, GJA4, RAI2, RBBP9, SIX2, SLC8A1, OGA, CERS1, CLDN16, SLC14A1, GNA13, LGI1, TIAF1, DBN1, KLF1, CELF2, DBP, DBT, CAMKK2, SLC18A1, TBXA2R, MYOM2, MASP2, SOX1, EEF2, PPP1R11, SLAMF1, CYP51A1, SLC1A3, HCP5, MEGF8, TRA, SLC4A1, P2RX6, TCP1, NCKAP1, SLC5A1, ZNF266, DHS, ZMYND11, SLC6A6, ATG12, SLC6A12, TRAF3IP2, SLC7A1, PCSK7, SLCO1A2, S1PR3, ARID3B, DHRS3, FBLN5, LPXN, TMPRSS11D, DVL3, NCR2, TAF1, DUT, TACC1, GGPS1, EIF4E2, SYN1, GMDS, ONECUT2, DFFA, SLC4A7, SOD3, LYPLA1, DGCR, GAL3ST1, DGUOK, LITAF, FFAR2, GLI3, ZFYVE9, SOCS6, RBCK1, SLC22A5, PRPF8, RPS6KA5, SLN, TBP, BCL7B, DDX1, COPB2, ASIC3, E2F5, ARFGEF1, SPTLC1, CNOT8, ARL6IP5, ITGBL1, RNASEH2A, EBF1, SNCB, DDX10, XRS, SGPL1, VIPR2, UPK2, CLIP1, MPC2, PRKD2, RASGRP3, NCOA4, SLC25A16, FKBP1AP4, RP9, SHOC2, PNKD, FKBP1AP3, FKBP1A, PXDN, HBE1, RYK, SSBP2, CASP14, RHOQ, FJX1, FCGRT, WNT7B, RPL34, GCA, VSNL1, CSNK1D, FGL1, WARS1, SIN3A, CR2, EIF4H, PLXNB2, VEGFB, ZNF148, CLIP2, SLC39A7, PRPF6, RSU1, MXRA5, BRD3, UMPS, CRAT, PTP4A1, DNM3, PPP1R15A, TIAM2, PES1, ABI3BP, GABARAPL1, FLNC, CRYGC, SH2B1, KLK13, CSRP3, CRIP1, UBP1, PTPN23, HBZ, RPE, FKBP1AP1, FKBP1AP2, RPLP1, FGF5, VASP, EOS, CSNK1G2, UCP1, WBP2, FDFT1, ZNF224, SERPIND1, NNT, BEST1, FGF20, TFIP11, DDAH1, RPS15, FHL1, RPS6KB2, ZIC2, NGDN, TTPA, TIPARP, FOXD1, FGF21, PSD4, CENPX, FAM13C, NEUROG1, TSIX, HNRNPUL2, PPT2, ADAM32, SLC16A9, MED23, ZSCAN4, IATPR, HTRA4, MED17, TUBB, ZBTB7C, ACADS, SEMA3B-AS1, PTCSC2, TAF4B, OTUD1, DVL2, RTKN2, EMSLR, HYLS1, UNC5B, LINC01679, GM2A, LINC01537, SPATA19, CYP7B1, HAND1, USP12, SFTA1P, DOK6, GLRX, LINC01927, GLG1, TRIML2, USF3, CCDC83, ECEL1, TALDO1, TGFBRAP1, TMEM31, MYLKP1, NFYA, FRG1, KLHDC8B, MIR6803, CALML6, IFNLR1, LEXM, SASS6, THRIL, NIT1, APOBEC3H, DUSP8, DNAJB8, ADAMTS4, MIR6734, MIR8073, ADGRA3, MIR6775, SGMS2, VAMP7, CDC20B, MIR6126, GBP6, FBXO39, SVIL, GOSR1, RHOXF1, ELF3-AS1, SULT1A3, NKX2-3, ACADL, SUPT5H, DEUP1, ABCC8, ALDH1L2, NMBR, STOML3, SYNE3, CLEC14A, MDGA2, TMEM59, OTUD7A, SPRED1, ADAMTS2, BHLHA15, RPL22L1, UPK1B, NSMCE1, TTC21A, CADM4, NIBAN3, ADM5, LRP4, CYP4Z1, TXLNA, THEMIS2, SLC30A8, NFYC, B4GALT1-AS1, PCYT1B, IL27RA, TMEM17, TIGD1, LIPH, ARL13B, PCAT14, XCL2, UBR1, MED20, PAGE4, GLIS3, SPIN3, HTR3C, FBXW7-AS1, ADAMTS15, MAGED1, ABHD11-AS1, TBX4, PCBP2-OT1, PTCRA, MAPK8IP1, B3GNT6, PRXL2C, INSL4, RMST, ANO6, TMEM201, MAPK15, ZUP1, HOXC-AS3, ATP6V1C1, EMC10, NDUFS1, EDN3, LINC00663, UBE2D1, LCN1, EPHA10, TCEA1, TBRG4, NDUFAB1, DLGAP2, HLCS-IT1, STPG4, DUSP28, NDP, EPHA6, MAGI1, LINC00210, SIGLEC15, ADGRF4, HCCAT5, FGF14-AS2, SIAH3, SLC46A3, UBE2L1, LINC00641, EWSAT1, PGP, LINC00514, FBXL19-AS1, UBE2D2, HID1, KANSL1, PICART1, CISD3, GSDMA, LTBP2, GPR50, GCM2, SLC9C1, ZNF385D-AS2, SUMF1, SLC16A7, MIR5100, LRRFIP1, EIF4E3, ITGA1, CCDC85C, DDX51, CELIAC2, NUBP1, MMAB, CYP4V2, UBE2B, S100A7A, ZFY, DEDD, MMS, RAB7B, REPS2, TAS2R18P, LIN9, MIR5195, LRRFIP2, MIR5590, F11-AS1, SH3PXD2B, LTK, TCEA2, RNF180, LY6E, ZBTB14, RGMB, FSBP, TCEA3, NCK1, ELOC, NSMCE2, FAM83H, HEIH, NCF4, NCBP1, ATP6V1E1, UBE2G1, FOXD3-AS1, NAALADL2, STXBP4, UBE4A, NEFM, ECE1, EBF3, RPL23, PTENP1-AS, B4GALT5, AVPR2, FGG, LINC01018, ANKK1, EPGN, MBLAC1, ECHS1, MMP20, RPL10A, TMEM196, NEFH, AZF1, SPESP1, NEK1, KIF3B, TARBP1, UCHL3, ROR1-AS1, GPC2, BRAT1, RUNDC3A-AS1, XK, NEK3, LRWD1, ASIC2, AZU1, FAM83B, UNC5CL, SCUBE3, GPR183, ATP6V0D2, NPTN-IT1, TCERG1L, HECTD4, ZNF311, RGL4, NDUFS8, NAP1L5, ADGRF1, FGF12, TBX15, MFHAS1, RAB40AL, CACNA2D2, CD83, NDUFS2, ATP6V0A1, FPR3, BCL9L, P4HA3, SLC22A24, OR10A4, NUMBL, MAGEA2B, STEAP2, STK17A, FDCSP, NPB, KANK3, GCSAM, NEGR1, SHPRH, KLHL34, TAB3, TBCE, SGMS1, SERPINA7, IFNL4, TAS2R46, UBE2L3, OPN1MW3, IS1, BCL7C, PYDC1, MOSPD2, NME4, CT45A9, MAML1, SLC25A29, LHCGR, TOMM20, IL12RB1, DAZAP2, TMEM219, BNC1, CANT1, SLC43A2, GJB4, SPNS2, RN7SK, CKAP5, TNFAIP8L1, MFSD12, WTIP, HSPB6, ANKLE1, CAMTA1-DT, TC2N, SPOCK2, IL9R, TPM1-AS, OAS2, TMEM45B, CYP2R1, DBX1, NVL, TMEM52B, ARHGAP11A, GNB3, IKBIP, CUL7, TSC22D2, DRD5, RNF40, TDRD9, ANKRD9, C14orf28, TDRD10, LOC110366354, PRUNE2, COL6A6, TBC1D5, OSR1, AHSA2P, TM9SF4, GNB1, CRYBG3, SOX2-SRR2, IL13RA1, TMEM207, HMGB4, OCIAD2, FOXJ1, JADE3, CPEB2, LOC107987479, KIAA0513, EMB, LZTS3, SGPP2, AP1S3, BLVRB, NEU4, SERTAD2, GOLT1A, KLF17, NTF4, NAXE, PIFO, VGF, PROKR2, KRT7-AS, SNORD138, TALAM1, ZNF280A, FOXD2, SGSM1, PIEZO1, NTF3, FBLN7, ARHGEF11, OAS3, GCASPC, ATG4A, PAN2, GPRASP2, H3P5, ST2, USF2, VASN, ORC5, MARCHF3, KCTD12, EXOSC6, NCAPD2, FBXO17, FCRL1, FCRL3, UQCRC2, ARHGEF25, USH2A, UBAP2L, FBXO32, SSX5, OSBPL1A, JOSD1, BUD23, ORM1, UROS, SLC2A13, LACTB, CGB1, CGB2, BPI, TIRAP, GFPT2, RBM8A, PGLYRP2, PUM3, FMNL2, SLITRK1, ESCO1, RHPN1, TENT5B, IL5, UQCRC1, OLIG1, FARP2, C2CD5, H3P7, DUS4L-BCAP29, OMD, ELMO1, SCGB3A2, ZBTB24, SSX2IP, VBP1, OAZ1, SLC16A10, OAT, PARD3B, GNG4, ANTXR2, MUCL1, MRGPRF, PJA2, RASGRP4, SLC26A8, H3P24, FMO5, DENND2B, DST, AAMP, ST8, DIRC1, FCHSD2, SEC24D, AREL1, UQCRB, FAM210B, AANAT, CMTM5, OGDH, PANX3, GNG7, NPY5R, DNAJC21, AFAP1L1, TTL, SULT1A2, BCRP4, SRARP, RNF187, COMMD7, TNFRSF17, STRN, NFAM1, CKAP2L, SNHG14, SATB2-AS1, ABCG1, PROM2, SEPTIN10, KANSL1L, BCL7A, GPBAR1, LRATD1, GLIS1, B3GALNT2, OVAAL, FAM163A, TMC8, PCAT29, SH3PXD2A, C18orf25, INCENP, STK4, LAT2, ABR, SPC24, CCDC155, DACT3, NLRP4, LINC01419, FNTA, TESMIN, PTPRVP, CASC21, STX1A, GDA, UPP2, CDC42BPB, SPINT1-AS1, AGR3, NR1D1, LCT, GTF2IRD1, GABBR2, ANKRD46, HPCX, FBXO16, LINC00599, WWOX-AS1, H6PD, SBSPON, LINC00032, GATD3B, CT45A8, SHOC1, KCTD7, AMOTL1, FPGS, HCAR2, LNCTAM34A, PITPNM1, STX4, NMT1, CMTM8, IER2, SLC26A2, NIPAL1, STX5, SHISA3, CBSL, MAD2L1BP, CREB5, ENTPD4, LPP, BTNL9, RUNDC3B, PROCA1, LORICRIN, LOC107985770, FOXD1-AS1, FUNDC1, UPRT, MAGEE2, USP34, LARP1BP2, GAB3, CST12P, NPPB, DOCK4, CTR9, DCAF1, BPIFA2, LOC105980073, NPPA, VLDLR, MACROD2, NKILA, USP6NL, RNU6-392P, PWWP3B, PASD1, DBH-AS1, FOXL1, BLK, ORI6, NPY2R, C6orf141, MUCL3, KLF14, ASZ1, ABCF1, GNAI3, UGT8, NPR3, MIR34AHG, RN7SL494P, UBXN2B, RIPOR2, TAF1L, LMX1A, LINC01980, KRT72, PPP6R2, TRAM2, RFLNA, WDR66, GREB1, GNAI1, IPO13, BDH1, SAFB2, DRAIC, GNA15, TTBK2, TEKT5, IMPA2, STK3, RBFOX3, SLC47A2, IMPDH2, UGT2B4, LAYN, SRXN1, ARHGAP42, VRK2, ILF2, LINC00261, ISM1, CST11, LMX1B, KIAA0100, RAB40A, VTI1A, UGT2B10, XRRA1, UBQLNL, ERVK3-1, MUC15, PERCC1, SESN3, CFB, UBA7, ACER2, GJA8, MIR1197, MIR510, HAS2-AS1, NPS, MIR1305, EVPL, DEFA1A3, PBCA, CGGBP1, ADRA2C, ADORA2B, MIR1301, GHS, MIR1179, NRON, BCAS1, TUB, ADORA3, COPS3, GABPB1, EPM2A, DEGS1, MEOX2, MIR520A, MIR526B, MIR525, MIR520B, GPC4, BABAM2-AS1, MIR518C, MIR524, MIR1267, KMO, MIR520D, ADRB1, MFAP4, THOC5, MIR1227, MEST, MEP1A, MIR2053, BCRP1, RRP1, MIR1231, TTN, NCF1, SLC37A4, ADH5, MIR1307, MIR1321, MIR1233-1, PHLDB3, GSTT2B, BCRP3, ZG16, GPR65, OCM, TOP3A, PAX8-AS1, MIR1249, SORBS2, LAMA2, ST7, RANBP3, MIR1204, CNTNAP1, NR2F2-AS1, MT1IP, SEM1, CST7, ADORA2A, CYP4F2, DGKD, DGKE, RPSAP11, MIR1827, TPTE2P1, LYPD8, MIR1909, ELP1, ITGA10, MIR1228, CASTOR1, MIR519C, FAS-AS1, SMAD9, MLN, EID3, RBMXL1, ESRRG, MIR376A1, LAMTOR3, AFF1, ABCB11, CHRD, ETFB, TMPO, PTCH2, AOC3, EIF4EBP3, TMOD1, CLEC18B, ANIB3, A1BG-AS1, RTCA, DDX3Y, TRPM1, ERV3-1, ERF, MN1, CDC23, MMP16, TLE3, STX11, B4GALNT1, KCNN3, EIF3J, EIF3I, MIR3188, KCNN4, MIR4319, LINC02532, AIC, LOC100422227, KIR2DL2, BAG6, UNC5C, JRK, MGAT1, LST1, ADSL, DDX39B, MIR663B, PLPP1, GABRE, MIR718, KLRC2, TMEFF1, MIR492, SSX4B, PRKRA, SLC25A5-AS1, AKR7A2, GRK3, ZEB2-AS1, TNFAIP1, PLA2G7, MIR181D, MIP, PLPP2, AEBP1, MIR323B, CKMT1A, ECT, BOLA2, RFXANK, JPX, ACY1, KLRB1, GABRP, CDK13, CLDN5, PGM5-AS1, CLEC3B, MIR363, MIR20B, PLPP3, MIPEP, MIR431, MIR1248, EXTL1, KCNK18, FANCF, CT45A2, UNC5B-AS1, TEX46, EOMES, ADCY8, SFTPA2, TRE-TTC3-1, AGAP2-AS1, LOC730101, CCT3, TDRG1, CEMP1, MAP6, MIR767, H3-4, EPX, USP9Y, VIM2P, MARS1, TNRC6C-AS1, TPTE, FKTN, CARMN, LALBA, H2BC21, HBD, DEFA1B, H2BC9, H2AC20, H2AC18, HOXA-AS3, FCGR1CP, FOXO6, LINC00271, RAB6C-AS1, FZD8, OPN1MW2, ACSL3, CCDC30, TRH, MIR770, MBD1, TSNAX, MAN2A1, MIR877, MIR665, SLC2A3P1, AFF3, MIR374B, EGOT, MIR365A, MIR935, TRIP6, MS4A2, MAGOH, GAN, MAGEB2, FSHMD1A, MIR939, MIR937, CDK2AP1, ST8SIA6-AS1, MFAP5, MIR875, MIR541, ESRG, PUDP, SNORD116-20, KRT81, TLX1NB, ADCY3, MAPT-AS1, MCTS2P, SNORD126, TEC, GATA6-AS1, ZGLP1, VPS9D1-AS1, FMR1-AS1, MIR298, GATD3A, FCGR2B, DIP, LINC01433, MIR1287, MIR593, MAFD2, MIR575, LIMS4, CMAHP, BCAR3, MIR587, EEA1, F2RL2, MIR596, SLC25A11, MIR597, MIR598, MIR599, MIR603, TPM2, MIR607, SOX14, LOXL1-AS1, STK24, MAF, MIR561, MIR556, MIR544A, MIR545, MIR1470, MIR1288, DUSP11, SNORA80E, GNPAT, PPAN-P2RY11, NSMAF, RASAL1, KRT1, FRA14B, MIR532, CAVIN2, KDSR, TTC4, DEFB4B, MIR612, PIP4K2B, KRT31, MCF2, MIR655, MIR657, LINC00899, CUBN, PCED1B-AS1, SNORD118, MANCR, MAFIP, RAMP2-AS1, NME5, ANXA8L1, NUTM2A, LINC00092, LINC00426, FCN1, MIR1225, AD11, HEY, MIR654, TST, GACAT2, H2AC19, LINC00941, F11, F12, MIR627, F13A1, FUT6, LHX3, MIR632, FABP6, MIR635, MIR637, FABP7, FUT3, MIR645, KRT15, FANCE, H3P36, B4GALT3, PAGE1, KCNK2, M6PR, TMPRSS11F, ASH2L, CLDN12, FEZF1, LBP, UBE2NL, C1QL3, SLC7A7, OR3A4P, MYO18A, HES3, UOX, VHLL, FLT1P1, PSTPIP1, HELT, BRCA1P1, MYO9B, C2orf68, LINC01138, CLDN10, SBK1, MYOG, CEP85L, PKMYT1, THEMIS, ILDR2, SLC16A12, C10orf143, PPT2-EGFL8, MICOS10-NBL1, CLEC12B, ITGA2B, C1QTNF9B, FRA1A, SHISA2, MYOC, ZNF154, ARMCX5-GPRASP2, TRIM26, MIR100HG, TMPOP2, MIRLET7G, MCPH1-AS1, PLOD3, ZNF195, P4HA2, MYH8, IDH1-AS1, NBR1, MIRLET7F1, MYF5, GDI2, RERE, KYNU, MIR101-2, MIR105-1, TOP3B, NR2F1, ELF1, ASTN1, SOX21-AS1, SCGB1D4, TFAP4, ZNF185, ST20, EIF2B1, CAHM, UBE2M, GDF10, TEX19, EIF2S3, PAIP2B, EIF4EBP2, CELA1, RBM14-RBM4, C4orf3, HAP1, RNF113A, MYLK, SOHLH1, LINC00968, ZNF664-RFLNA, ZNF582-AS1, NOL4, RFPL4A, GLDN, SLC6A5, C16orf96, ATXN1L, ZNF404, ZNF677, MIR4474, MIR1343, ZNF354A, IGFBPL1, SYNGR2, IRGM, MCIDAS, MIR4644, ZNF84, MIR4784, EFNA5, RABEP1, NEK5, UBC, MAGEA6, MIR1269B, B4GALNT4, RAB43, SPGF2, MSL1, CNBP, ZNF23, LYL1, ZNF24, C3orf35, GJA3, ERVW-4, TMPRSS11A, NAIP, ATP5F1A, EEF1G, NRBP2, COX7A2L, ATP2B4, ARSH, TRD, LHFPL4, PTCHD3, CELSR3, CCDC178, TMEM205, SBSN, MTMR7, LINC01116, MIR499B, ENHO, NAGLU, AGRN, MYT1, MTMR6, PICSAR, MIR4728, ATP1B2, RNF144A-AS1, ZNF132, NDUFS7, DND1, INA, EFNB3, MIR4802, MIR4516, SLC35B2, MIR4717, NME9, ATP2B2, RBPMS2, ARPIN, TCN2, MIR4709, MIR4500, MIR4465, PLET1, DNAAF3, MIR4779, PDLIM1, PCNAP1, MINCR, HERC2, ZMYM2, KCNA4, SCG2, PCAT19, MSRA, AMPD2, JUP, MIR3666, MSH5, RGS11, MIR3662, MIR3609, CITED1, MIR3648-1, AMD1P2, GAS8, RAB11A, MIR642B, FGD1, GALNT3, IVL, LINC01133, MALINC1, MSX2, LINC01503, SOX1-OT, DMTN, MIR24-2, LIN7A, MIR26A1, SMAD1, ACVR2B, APTR, GBAP1, IVD, SNHG18, GALR2, FRA9E, MIR299, THM, AMT, MIR92A1, MS, GCSH, MIR151A, BECN2, KCNJ4, RNGTT, ALDH9A1, RNMT, ABCD1, ALAD, AK4, MIR4284, STX2, MIR3129, MIR302D, CTSF, MIR324, MIR325, RAB7A, ICAM5, TLE2, MANF, NRARP, MTHFD2L, GPAA1, MIR23C, ALPL, LAMB1, FRA11H, TK2, BLID, MIR3163, KCNJ1, MIR4262, KCNJ2, PLIN5, ZNF506, MICOS10, MAP1LC3C, PIWIL3, GALR1, MIR3151, ENSA, ANK3, SLC25A4, DDX18, MUC7, MIR147A, ARHGDIA, LINC00629, EIF2B2, ITGB5, EIF2B4, MCM3AP, NAE1, CD84, DNALI1, ITGB8, ARF3, PIK3IP1, MIR181B1, RNR2, PXN-AS1, TFR2, RHOH, ARL2, ARL3, GAS1RR, OPN1MW, ASL, CACNA1G, MAA, MIR128-1, MYBPH, CACNA1I, ART1, ENDOU, GCNT2, ARSL, LINC00707, MIR138-2, ZFAND5, TYROBP, FGF6, MX1, VNN2, ITIH1, ITIH4, DAP3, HCAR3, TGM1, APEH, AIRE, EN2, APBB1, APBA2, NUDT2, MT1X, GBE1, LINC01093, AOX1, MT1M, TH, LINC00963, ACVR2A, TMEM11, MT3, APOC1, MTNR1B, CSDE1, LRP8, LAPTM5, ND1, MTM1, AQP2, MIR196A1, GAS6-DT, GCH1, EMD, LDB1, CYTB, LINC01006, COX3, GCGR, ITPKB, AKAP4, LINC00973, MCM3AP-AS1, ITPRIP, KLHDC7B, BTBD3, HOXB8, P2RX2, CEL, ANKHD1, CTH, CCL8, NCAPG2, CECR, HOXC@, CDKAL1, KIFAP3, PRSS2, MAPRE1, CCL15, TMEM260, CTNNA1P1, RASIP1, LIME1, IMPAD1, DUSP23, RALY, PRTN3, APTX, CCL1, CEP152, P4HTM, RRN3, PSMA4, SLC35F2, LIMCH1, MPHOSPH8, CENPE, LEPROT, PSMA2, PSG9, BCAS3, HYDIN, CEP131, PSG1, PSEN2, MED18, AHI1, PSD, QPCTL, PAXIP1, OCIAD1, PIGX, TFEC, CT55, PPM1E, AKIRIN2, CDSN, CEP192, HEATR1, ANO10, DLGAP4, ELP3, CTPS1, CCL24, CXCL6, CDS1, CDR2, IKZF3, HOXC11, CLCA4, RPRD1A, APPL2, DPPA4, RRAS2, HOXC13, PRPF38B, CRTAC1, ARHGAP17, CCL19, TMEM132A, ARSG, HCFC1R1, CARD8, CEP164, ZNF365, STX17, PID1, PHIP, FASTKD2, MAGOHB, ATG14, GABPB1-IT1, WIPI1, ENOX1, OXR1, KIF26B, ATG2B, ANKRD26, AGGF1, TMEM106B, CES1, CNOT1, CCNJ, CD244, DIP2A, ABRAXAS2, TMEM8B, FOXN3, MSMO1, TLX2, ZZEF1, GALNT7, SCN2A, POGZ, PANK1, TBC1D2B, SCN4B, S1PR5, P2RY13, PTGDR, RAB24, SCN9A, A4GALT, CPSF2, GHRL, CYFIP1, ATP11B, CDK5RAP1, NSG2, KLF13, DHRS7, ACSM3, SYNE2, TMBIM4, PTPN7, MRPS23, CHMP3, PTPN4, CES1P1, CSRP2, RRS1, FKBP7, ZFR, ASB4, SUFU, LSM7, ACSL5, ACSBG1, SLC37A1, HOXA6, SETD4, PDZD2, NMNAT2, CPVL, EPB41L4A-DT, DDX4, SCNN1B, PYY, GNL3L, DDX49, EPB41L4B, PSMB6, ZNF609, ZNF292, PHLPP2, SAMD4A, DOP1A, USP33, EQTN, L1TD1, PSMB1, INO80, SMOX, HOXB3, RIPK4, PSMD8, CHD2, TRIM35, EXPH5, HOXA7, PTAFR, RRP1B, SWAP70, GNG2, HOXB@, SETD1B, CHPF2, CAND2, SETX, SSH1, WAPL, HOXB1, PSMC2, MIEF1, PSMB10, PIMREG, LAMB4, SLC38A7, UPK1A, PCDHA@, CDK11B, CYP2A7, LMO3, SOX21, PRB4, NUDT5, MESP1, PRB3, THSD1, ERLIN2, GSTM4, PLAAT3, IL1RAPL1, INKA2, DMAP1, PPP6C, PPP5C, SLC7A9, BAIAP2L1, SLC50A1, BTN3A2, ASH1L, CYLC1, TMEM165, ADAP2, SEMG2, EXOC1, NGLY1, EXOC2, CEP250, SELENOW, ZNF415, CACNA2D3, DCP1A, PRCP, STRAP, FOXJ2, SLC2A6, BDP1, SEPTIN7, CDC5L, TREH, BAZ1A, ARHGAP15, PRCC, ALG1, TEX15, NEIL3, FGFR1OP, TPPP, AKIP1, SAR1A, PPP1R10, TMEM115, SLAMF8, GPR137, CD53, CYB561D2, FSTL5, UGGT1, KCMF1, TCIM, UBQLN4, CYP2C8, SGSH, PPP1R7, CPSF6, SMARCAD1, PPP1R3C, SGTA, POLE4, TWNK, LINC00470, PPP2R3A, TDRD1, SUSD2, BTNL2, KRR1, CTNNBL1, KYAT3, DAD1P1, PPP2R5A, PTPN21, PPAN, CD69, LTB4R2, SPACA9, DNAJC12, SFTPC, DIDO1, PPP2R2A, INPP5E, SGCA, RER1, UGGT2, CDK5RAP2, PRG2, CCAR1, GPN1, GUCA2B, PIDD1, MAPK4, PNKP, PARL, MGAT4B, POU6F2, CTSH, MACROH2A2, PRKG1, KLF12, HOXD11, PRKCQ, ATXN2L, CDC34, NRM, DDX19B, SNF8, DUSP12, SP140, TMEM63B, TMC6, VSIG4, GABARAP, CASC3, MRGBP, MAP11, SYNPO, NUDT15, MAP2K6, TMEM100, VPS53, CDH12, RNF121, HOXD4, DDX19A, GYPE, GYPB, GUK1, SYNJ2BP, NIPSNAP3B, GIMAP5, FKBP9, STK32B, SEA, STAB2, SUPT20H, HPV6AI1, DDX27, RNF139, MFN1, LIMS2, POLG2, PRAF2, RADIL, IARS2, ARHGEF40, IPO9, RNF126, GALNT5, GTF3A, CEP72, HPX, C1orf112, HHAT, IRAK3, PRIM1, CNDP2, PRPF40A, PRKAB2, CHRNA9, TP53TG1, UBE2Q1, VEZT, HPCAL1, RNPC3, ITLN1, DCTN3, TENT5A, KIF21A, VPS50, HRH3, SEC14L1, STAP2, THUMPD1, AMBRA1, MAN1B1, G2E3, PRKACA, PTGDR2, ZHX1, RAB20, SCFD1, CHRM1, PIAS4, BACE2, IGLJ2, IGKV3-20, DCAF13, COL5A1, RPL18, CRHR2, MOB4, MAGEH1, METTL7A, DBNL, NTMT1, COMMD5, MACROD1, COL3A1, NIPBL, SLC43A3, POU2F3, TMEM184B, ZBTB44, FBXL2, HIVEP1, IGLV3-21, POLR1A, TRIM58, RPL11, NECTIN3, COL13A1, COL12A1, APOBEC3C, RFX5, RFX2, RPL10, COL10A1, PCLO, IGHV4-34, HHEX, ZDHHC5, CRHBP, TMEM158, MTHFD1L, TRDJ1, TRDD3, TRDC, COL9A3, COL9A1, MED4, REG1CP, EXOC7, DNAJC15, NPC1L1, ZNF318, SNX10, STRN4, PSMC3IP, MYLPF, GPSM2, CCDC106, HOOK2, UBIAD1, CNC2, HILPDA, EPN1, GPR132, DSE, CLDN15, PANX1, OSGIN1, NAA80, DPP7, POMT2, TP53TG3, HLA-DOB, PRPF40B, ANKRD11, N6AMT1, HIVEP2, MTO1, HLA-DMA, RPL24, RPL30, TAFA5, RPL29, TTLL1, LGALS13, SUN2, CNP, RCN1, CNN2, RPL31, TMOD2, QPCT, FBXO7, CYP2S1, RAB3GAP2, POLL, SYF2, EIF3K, ADGRA2, FBXL3, NBEA, CHORDC1, RNF11, FETUB, DNAJC2, USP21, TPK1, SENP3, DNAI1, NPTN, RGS22, RIBC2, PHF19, TRPC4AP, RPA2, LDLRAP1, CPD, RIEG2, SZRD1, ANKRD1, RANBP6, CFHR1, RNU1-1, NKX2-8, GAPDHS, PLA2G2D, FBXO3, HDLBP, FBXO6, LIG3, CNNM3, RNPEP, RNF6, HEXA, CPT1B, CPS1, DAZAP1, RNASE4, RORB, PTTG3P, LCE2B, FBXL4, RNASE2, SNORD48, CHTOP, VPS41, HERC4, SLC31A2, IL17C, OSBPL3, RGS7, C5AR2, GNMT, GPKOW, GPR162, SIT1, TMEM98, UPF2, IL36A, CRABP2, RPL3, SPINK4, ULK3, KRT23, PGAP2, RBMX, EGFL6, RGS2, SIGLEC9, CORT, TSPAN13, AFF4, LYPD3, RHEB, CR1, CACYBP, SENP6, COX7B, DKK4, COX7A2, INPP5J, INVS, SLC39A1, SNX5, MORC1, SS18L1, STK36, COX5B, CRABP1, GLCE, RGS10, PRELID1, LAMP5, MRM2, RBBP7, HMGB3, NRN1, ZDHHC3, RAB5C, SLC22A17, RXRG, SLC25A37, GASK1B, RABIF, SPG21, SF3B3, OTP, CRNKL1, CHRNB4, KRT76, RYR1, MBTPS2, HOOK1, CDC40, GRIP1, ZFPM2, CSNK1G3, ABCB9, HEY1, RXRB, ABI3, HAO2, DAAM2, CRBN, HERC5, CKMT2, RAD23A, GP6, ISCU, CSNK1A1, CRIM1, CKMT1B, MZB1, RTN1, NPTXR, CBX6, GCAT, UBAP1, KLF3, MAPKAPK5-AS1, IER5, POMP, FRAT2, RAB2A, NCAN, ONECUT1, ESYT1, CXXC5, GSKIP, ANAPC11, TRMO, PHF7, SASH1, NEDD4L, TUT4, SUN1, CSRP1, LGSN, RAB6B, ICOSLG, KIF13B, SAA3P, MGA, LARP7, ADGRL2, HADHB, UFC1, ATP13A2, SRGAP2, CSAD, WNT16, HARS1, PPME1, NOL7, BIN2, PRKAG2, CHRNB3, PZP, HAL, TRIAP1, HPCAL4, CSNK2B, IP6K2, PCYT2, SFMBT1, ARHGEF12, HMOX2, HADH, NOP16, PLEKHO1, MYO15A, MTCH2, AP2M1, KLK12, CRNN, LTB4R, CA14, PLA2G3, MINK1, PRND, CBLC, RARG, BACE1, IL20, NTSR2, HLA-DRB5, DEF6, CUZD1, CYHR1, SH3BP1, ANO7, PHLDA3, CD2AP, CRYM, RARS1, HLA-DRB4, TAX1BP3, PRKD3, A1CF, FLRT2, SLC39A3, SLC39A2, RBBP4, BICRA, PISD, PPIL2, CRX, RASGRF2, PIK3R4, RPS2, VSX1, RPS4X, RASA2, CXXC1, NT5C, CD209, EHD3, HLA-DRA, MYEF2, RPS10, AK3, HCK, RPS14, CRYL1, KLHL5, GTPBP4, UTP18, PHF20L1, TSPAN15, CDK20, RPS24, GOLGA7, FAM135B, PIK3R5, HSD17B12, A4GNT, CLCF1, ACAP2, SLC45A2, JPT1, ANP32C, DBR1, RPS12, PLEKHA8P1, HP1BP3, TMED5, HDGFL3, TAS2R13, CLTC, CLTA, NTM, CLPTM1, BHD, ORC6, HMSNO, TPRKB, CS, MED31, HEBP2, FAM215A, KLHDC2, ISOC1, RRP15, RPS11, ST8SIA3, PRLH, ADRM1, ENY2, CYP2U1, FAM172A, TLCD3B, ATG10, IFNA17, GRWD1, ZNF484, LONP2, USP26, ROPN1L, ANGPTL6, KLF16, LDLRAD4, ATAD3B, RAB34, APC2, BCO2, MAEA, TRAIP, PRSS27, SF3A1, BCAS2, GPR3, SOX12, PDGFRL, TRAPPC9, AIF1L, FCRL4, TCF7L1, SH3BGRL3, LAMC3, MXD3, DOHH, SCRT1, PLVAP, TCIRG1, GPR101, CTPP, CCNO, CA5A, PDE6B, TMEM50B, ZNF267, RAMAC, APBB3, TLN2, PARP9, EFS, GAS8-AS1, L3MBTL3, SP4, DCUN1D5, C6, HSDL2, ALKBH7, RPAIN, GPM6B, POLDIP3, RNF135, PRXL2A, PCSK5, PCSK1, UQCC2, CHCHD6, KLRG1, ELOF1, PCP4, C15orf48, CHMP1A, IFNGR1, SSX3, GPM6A, ZCCHC9, RHBDD1, HNRNPR, CEP78, OBSCN, STAG1, SP100, FSTL3, ZMPSTE24, TKTL2, PRAM1, ZIC4, ATRIP, UTP15, MEX3B, CCR10, RNASEH2C, RIDA, ASCC2, IFNAR1, GPHN, IFNAR2, SETD3, USP48, SMYD5, CNPY2, ZNF205-AS1, ST6GALNAC5, PFDN6, RUFY1, MCHR1, CEP63, TRIM45, SLC30A9, CFD, SP110, EPC1, DFFB, GPR18, ZKSCAN3, ABTB1, FAM3C, CFP, ULBP1, SORL1, TRAF3IP3, COASY, RBM14, PEPD, ALPK1, RUNX1-IT1, CHD9, TUBA4B, MINDY3, WWC2, DGLUCY, DEFB4A, UBTD1, NRSN2, PANK2, SEMA6D, EIF3M, BAIAP2L2, TADA3, FRAS1, CFI, GPR31, NAA15, DBF4B, SPSB1, RNF34, ATP5PD, HKDC1, AKNA, ESX1, PGRMC2, MICU1, PDZK1, TRIM11, SLC26A4, PDRG1, TRIM8, DIO2, FAM83D, CACNG2, UNC93B1, HMG20B, VOPP1, VMP1, TFG, ADAMTS12, NETO2, NETO1, PDK3, TRIM56, RNF146, PDK2, YIPF5, GDPD5, SLC44A4, DIAPH2, LIMD2, CMIP, MYCNOS, DDHD1, BHLHB9, DUSP16, GPR12, KDM7A, IFIT2, ILKAP, CACNA1D, PRG3, ANAPC10, CACNA1F, OR51E2, DCSTAMP, TUBB4B, ITFG1, SGPP1, SEPTIN1, DDX39A, SPINK2, EMSY, DGCR2, ANKRD30A, TRIM47, DERL3, SESTD1, RCCD1, ISX, RPS19BP1, ZNF830, P2RY11, NEXN, SMDT1, SSBP1, DNM2, ALKBH8, TRDMT1, TANK, ABI1, ACOT8, NAALAD2, TMEM88, NR2E3, GNE, GOLGB1, GOT1, BMF, ABCF2, UNC5A, DNASE1L1, CTU1, DCAF15, MED30, IFT20, MCFD2, KNSTRN, DNASE1L3, SPSB3, ABCC5, IL1RAP, SAE1, N4BP2L1, ZFAND2A, COX19, LRSAM1, PAGE5, ZNF598, TMEM132C, CHMP4C, EIF1, SPECC1, PPP1R14A, FNIP1, THRAP3, LIMS3, OVGP1, SLC23A2, CAVIN3, OTX1, BST1, ZFP36L2, USP3, ZFP36L1, CFAP36, OTC, AHNAK2, GOLGA1, LARP4, TMEM106A, BRDT, MAGEC1, CMTM1, SSTR1, NUP153, ABCC12, LEMD1, G6PC3, TIFA, MAFG-DT, OTOP2, SHKBP1, UBE2Q2, P2RX3, SSR1, PRDM6, ZFAND4, NR1D2, REC8, ST7-AS1, P2RX1, SSR3, OXTR, PIGS, GOLGA4, BTD, OXCT1, TSPAN18, KLC4, SRP68, TRIM15, LNX1, PLEKHA8, FARP1, CAPN5, USP30, PCGF1, IGHA1, PYROXD2, C19orf48, RTN4IP1, IL17RC, LMNB2, FCRLA, TRIM52, ZNF503, CEBPZ, TMEM25, IGHD, C4BPB, IGHE, MFSD2A, GPT2, CHST4, GPD1, LHFPL6, PCMT1, RHOXF2, MRPL43, PCK1, TXNDC9, ZGPAT, FNDC1, PCDHGC3, PCBD1, EBPL, DHRS9, SPP2, IGFALS, C5, CCDC62, PAX9, HES7, TRIM63, DSCR8, PAX4, AIFM2, SPPL2A, SLC7A3, ARPC5, PAFAH1B2, DMPK, FURIN, TSPAN2, ZIC5, CCNB3, GP1BA, LRRCC1, GBGT1, DNAH5, HIPK3, DIXDC1, SSH2, SCIN, C3, PNPT1, C1QA, SRMS, GPC6, KLHL6, MYLK2, KRT88P, ADO, HSH2D, SPR, ARHGEF39, CLEC3A, AKAP9, UTP4, PPP1R15B, PAK3, ATG4C, PWWP3A, MAEL, KRT90P, LINC01587, SPRR3, SPTA1, AJUBA, TOX2, SNHG7, COX14, FRY, H2BC12, SNX1, SEC23A, CAP2, SIGIRR, SLC1A4, RUVBL2, GRIN2D, CTDSP1, CCNT1, CD3EAP, RHOU, SLC2A2, RPRD1B, PDE10A, PRUNE1, GRIN2A, NOXA1, DAD1, STARD10, RBM25, PRM3, PMP2, HIVEP3, ACE2, SLC4A2, C6orf47, RAP2C, HCST, PRX, SUGT1, PNPLA6, BLCAP, SKIV2L, RDH14, GPAM, RAB10, CPNE5, SEMA4G, PROKR1, GRHL3, HSD17B2, WDR19, WDR3, POLA1, HSF2, GATAD1, POLD4, ME3, LSM2, IQGAP2, HRH4, DSN1, ZNF271P, ZNF667, NECAB3, GRAP, KLRA1P, KIF13A, NEUROD6, SLC7A4, PLP1, RAI1, ERVK-6, PRSS22, NPAS3, LHPP, DGKG, DAO, ELSPBP1, CCKAR, MAGEF1, GRIK3, KYAT1, RRAGC, XPNPEP3, CHP2, ANKEF1, PLXNB3, SLC25A19, GRIN1, ELOVL5, HSPA6, AASDHPPT, TOB2, ALX4, DGKB, ATG101, PROK2, SLC7A2, PAPPA2, BCAN, RNF123, UBE2O, PIEZO2, PLXNA1, SLC17A9, GALNT11, CHTF18, UTS2, STIM2, SHROOM3, JCAD, HRH1, GSK3A, KMT5AP1, CTSA, CAMK1D, PPBP, MS4A3, SLC27A2, SLC27A5, HRG, SF3B2, CYP2D7, SIAH1, FERMT2, POU6F1, ZNFX1, ADIRF, SLC39A10, ADAMTSL3, MCOLN1, ASCC3, SPINK5, AVEN, PCNP, PRDM9, SH3BGRL, XAB2, PPP1R2, NIT2, RGMA, PARP6, ATXN7L3, PPP1CC, PRDM8, POGLUT1, CYP2C18, PPP1CB, SH3GL3, ENTPD2, RBPMS, KDELR2, CCNL1, SHC1, UTP3, TNFSF8, HSBP1, POU4F3, SMAGP, COPS8, POU1F1, GRM5, GPR158, PCDH19, PON2, CYP11B2, RNPS1, IGSF9, TAOK1, ARRDC3, CYP4A11, ZNF471, POLRMT, MAGED2, POLR2F, CD2, ZNF687, ADAM3A, FNIP2, TRMT9B, POU2AF1, NLGN4X, CXCL2, SIM1, PBXIP1, CYP2F1, TTYH1, CD7, IFI44L, ST3GAL3, ST8SIA1, GRM8, SLC24A3, HNRNPA0, MORF4L1, PLEKHG5, TENM2, C11orf58, UGT2A1, POP1, STRIP2, TBC1D24, AHRR, MORF4, SLC10A1, SLC11A1, PLIN1, GNPTAB, DDX6, BEND5, ARHGAP10, PPP1R3B, GRK6, NLRX1, SMPD2, SMS, RTL10, CENPU, SIGLEC1, SNAP25, MANEA, GALNT12, IPO4, CCDC51, PIGH, CANX, SERPINI1, ZNF385D, SLC25A22, USB1, AGPAT1, CAPN3, IFI44, PRR15L, CENPO, RABAC1, TTPAL, CAST, MMEL1, IBD2, ICA1, HAUS3, ICAM3, PIK3C2A, PAGR1, CAPZA1, SLC19A2, CHPF, PIK3C3, PIK3C2G, SLC35A1, ACSS3, ARMT1, SNIP1, NEBL, ELMO3, ADM2, CCDC134, MAP9, SEMA4F, SEMA6B, SNRPA1, SNRPB, SETD6, TCEAL4, CAMK2B, LINC00472, DEFA6, PGM1, SNRPG, ERMP1, CEP76, VAT1, WDR76, ATAT1, SNTA1, IDS, CBLL1, JHY, TXNDC15, PHKA2, CAMK2G, MICALL2, SUGCT, IPO7, FBXO31, GSDMD, HYOU1, DDX11, CHERP, SLTM, NEK11, DEAF1, MOB3B, DHX15, DEFA1, ID2, FFAR1, CSPP1, TLCD3A, LINC00115, TMEM243, PLEKHF1, DIO3OS, GPX7, NDST4, CLEC7A, TTTY15, PLCD1, CTAGE1, TMPRSS3, CBLB, PLCB4, SCGB1D2, S100PBP, DCT, SLC20A1, RBM15, SLCO2A1, EXO5, DDX31, NDST1, IVNS1ABP, PORCN, YTHDC2, POLR3G, SLC17A1, CIAO3, SUDS3, SLC15A1, SLC12A2, CORIN, FUT9, MMS19, SEMA4A, STRA6, SLC12A4, TENT4B, RAB17, RRAGA, INF2, PLCG2, HSPE1, GRIA4, ARHGAP9, AZI2, MMP25, DBH, ARAP3, DCLRE1C, STAMBP, GRIA1, RASAL3, MLPH, PVRIG, CASP5, PITX3, ATG9A, METTL16, HTR2C, ELOVL6, DSCC1, DCTPP1, HTR3A, TACC2, NPC2, CCT2, RNF26, HTR4, GRB14, DPYSL4, HUS1, FA2H, GDPD3, RAPGEF1, NUP37, TRIM3, CATR1, ST6GALNAC2, MRPL36, HTR1A, HTR1D, ACD, P3H4, PAICS, NBEAL1, SH2B2, HTR2B, CASP6, USP16, PKHD1, SLIT3, DLK2, DUSP26, OTUB2, COLEC10, RHPN1-AS1, VKORC1, NDC1
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Whooping Cough
Wikipedia
This explained the difficulties to reproduce results from different studies as the pre-inoculating handlings of the bacteria were not standardized among scientists. [25] Today it is established that at least some primate species are highly susceptible to B. pertussis and develop clinical whooping cough in high incidence when exposed to low inoculation doses. [26] [27] The bacteria may be present in wild animal populations, but this is not confirmed by laboratory diagnosis, although whooping cough is known among wild gorillas. [28] Several zoos also have a long-standing custom of vaccinating their primates against whooping cough. [29] Mechanism [ edit ] After the bacteria are inhaled, they initially adhere to the ciliated epithelium in the nasopharynx . ... Retrieved 12 February 2015 . ^ a b c "Pertussis (Whooping Cough) Complications" . cdc.gov . 28 August 2013. Archived from the original on 9 February 2015 . ... Retrieved 12 February 2015 . ^ a b c "Pertussis (Whooping Cough) Specimen Collection" . cdc.gov . 28 August 2013. Archived from the original on 8 February 2015 . ... S2CID 207217558 . ^ a b c d e f "Pertussis (Whooping Cough) Treatment" . cdc.gov . 28 August 2013. Archived from the original on 11 February 2015 .
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Hepatitis E
Wikipedia
For some of these reported conditions such as musculoskeletal or immune-mediated manifestations the relationship is not entirely clear, but for several neurological and blood conditions the relationship appears more consistent: [26] [27] [28] [29] Acute pancreatitis (HEV genotype 1 [5] ) Neurological complications (though the mechanism of neurological damage is unknown at this point. [11] ) include: Guillain-Barré syndrome (acute limb weakness due to nerve involvement), neuralgic amyotrophy (arm and shoulder weakness, also known as Parsonage-Turner syndrome), acute transverse myelitis and acute meningoencephalitis . ... Annals of Internal Medicine . 147 (1): 28–33. doi : 10.7326/0003-4819-147-1-200707030-00005 . ... Enfermedades Infecciosas y Microbiologia Clinica . 38 (1): 28–32. doi : 10.1016/j.eimc.2018.06.014 . ... "Hepatitis E and Pregnancy- Understanding the pathogenesis" . Liver International . 28 (9): 1190–1199. doi : 10.1111/j.1478-3231.2008.01840.x . ... "Nepal, hepatitis E epidemic: 9 dead and over 6 thousand infected" . www.asianews.it . ^ "Hepatitis E cases in Namibia rise to 490" . www.xinhuanet.com . Xinhua News. 28 January 2018. ^ "Weekly bulletins on outbreaks and other emergencies" (PDF) .NCKIPSD, AHI1, ASZ1, GPT, IFNG, NR4A3, CHN1, PGR, IFIH1, TGFB1, AMBP, BRD2, HPGDS, CPVL, TNF, CCDC88A, TSG101, GSTK1, SLCO6A1, APOE, VHLL, CD83, XRCC1, MIR221, MIR122, CDR3, DYRK3, GBF1, RIPK1, ROBO3, TMEM134, ISG15, FARP2, DDX58, IFNL1, IFNL3, HFM1, SIRPA, RBM45, ALB, STAT3, TLR4, IFIT1, APOA4, BST2, TNFRSF8, CYP1A1, SLC26A3, EGFR, EXT1, F2, F10, HLA-DRB1, HOXC5, HSPA5, HSPG2, IFNB1, TLR3, IK, IL6, IL10, IRF3, ITGA3, ITGAL, P4HB, ABCB1, PPIA, PSAP, RAF1, PLAAT4, SLCO1A2, BISPR
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Substance Use Disorder
Wikipedia
The DSM-5 includes specifiers for severity of a SUD. [1] Individuals who meet only 2 or 3 criteria are often deemed to have mild SUD. [1] Substance users who meet 4 or 5 criteria may have their SUD described as moderate, and persons meeting 6 or more criteria as severe. [1] In the DSM-5, the term drug addiction is synonymous with severe substance use disorder . [22] [24] The quantity of criteria met offer a rough gauge on the severity of illness, but licensed professionals will also take into account a more holistic view when assessing severity which includes specific consequences and behavioral patterns related to an individual's substance use. [1] They will also typically follow frequency of use over time, and assess for substance-specific consequences, such as the occurrence of blackouts, or arrests for driving under the influence of alcohol, when evaluating someone for an alcohol use disorder. [1] There are additional qualifiers for stages of remission that are based on the amount of time an individual with a diagnosis of a SUD has not met any of the 11 criteria except craving. [1] Some medical systems refer to an Addiction Severity Index to assess the severity of problems related to substance use. [25] The index assesses potential problems in seven categories: medical, employment/support, alcohol, other drug use, legal, family/social, and psychiatric. [26] Screening tools [ edit ] There are several different screening tools that have been validated for use with adolescents, such as the CRAFFT , and with adults, such as CAGE , AUDIT and DALI. [27] Laboratory tests to detect alcohol and other drugs in urine and blood may be useful during the assessment process to confirm a diagnosis, to establish a baseline, and later, to monitor progress. [28] However, since these tests measure recent substance use rather than chronic use or dependence, they are not recommended as screening tools. [28] Mechanisms [ edit ] Main articles: Addiction § Mechanisms , and Substance dependence § Biomolecular mechanisms Management [ edit ] Detoxification [ edit ] Depending on the severity of use, and the given substance, early treatment of acute withdrawal may include medical detoxification . ... "Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th edition)". Reference Reviews . 28 (3). doi : 10.1108/RR-10-2013-0256 . ... November 2016. pp. 35–37, 45, 63, 155, 317, 338 . Retrieved 28 January 2017 . ^ Butler SF, Budman SH, Goldman RJ, Newman FL, Beckley KE, Trottier D.ADARB2, MPC1, CDCP1, CSMD1, XYLT1, GBA3, TENM2, MYO5C, PARVA, WDR11, FRMD4A, PACS1, CCDC91, APPL2, CHCHD3, SLC45A2, PATJ, POLR1D, NME7, CD274, CTNNA3, FAM184B, TIAM2, RHBDD3, SYNE1, FKBP15, XPO6, SAMD4A, LIMCH1, PLA2R1, PCDH15, FAM184A, ZNF385D, TTC21B, TMPRSS7, HSPA12A, CERS6, ZNF366, C19orf18, OR51E1, LDLRAD3, C10orf82, MPP7, MACROD2, BPIFA2, ANO4, CSMD3, XKR4, SLC2A13, CADPS2, ZNF804A, AGBL4, FAM126A, RTL6, LRMDA, COLEC12, FHOD3, ZNF606, CSRNP3, SEMA6D, THSD4, ABCC4, KLF12, FARP1, ETV6, NRCAM, MYO6, MSRA, ABLIM1, AFF3, INSR, GRM7, GRM5, GRIK2, GRIA4, FHIT, FAAH, EHHADH, OPRM1, DSCAM, DRD2, DOCK1, DNAH8, DDX1, CYP2D6, CNR1, CHRNA5, CHRM2, CFTR, CDH13, ATP1B1, OPRD1, NPY, EIPR1, SLC10A2, SLK, CHD1L, CXCL14, AKAP7, NRXN3, PIWIL1, PRPF4, MKNK1, BCAR3, CSRP3, PBX1, SLC22A3, C5orf63, SLC6A4, RAD51B, QSOX1, PDE1C, PMAIP1, PRKCE, PRKCH, SLC18A2, FASLG, PTEN, HTR2C, GSK3B, KAT2B, NFASC, NCK2, PKNOX2, BDNF, OSR1, HTR2B, ANK3
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Toxic Heavy Metal
Wikipedia
For humans, typical presentations associated with exposure to any of the "classical" [27] toxic heavy metals, or chromium (another toxic heavy metal) or arsenic (a metalloid), are shown in the table. [28] Element Acute exposure usually a day or less Chronic exposure often months or years Cadmium Pneumonitis (lung inflammation) Lung cancer Osteomalacia (softening of bones) Proteinuria (excess protein in urine; possible kidney damage) Mercury Diarrhea Fever Vomiting Stomatitis (inflammation of gums and mouth) Nausea Nephrotic syndrome (nonspecific kidney disorder) Neurasthenia (neurotic disorder) Parageusia (metallic taste) Pink Disease (pain and pink discoloration of hands and feet) Tremor Lead Encephalopathy (brain dysfunction) Nausea Vomiting Anemia Encephalopathy Foot drop / wrist drop (palsy) Nephropathy (kidney disease) Chromium Gastrointestinal hemorrhage (bleeding) Hemolysis (red blood cell destruction) Acute renal failure Pulmonary fibrosis (lung scarring) Lung cancer Arsenic Nausea Vomiting Diarrhea Encephalopathy Multi-organ effects Arrhythmia Painful neuropathy Diabetes Hypopigmentation / Hyperkeratosis Cancer History [ edit ] The toxic effects of arsenic, mercury and lead were known to the ancients but methodical studies of the overall toxicity of heavy metals appear to date from only 1868. ... Cellular Effects of Heavy Metals . Springer. pp. 3 –28. ISBN 9789400704275 . Barceloux DG (1999). ... American Cancer Society. 2008 . Retrieved 2014-04-28 . "Chelation: Therapy or "Therapy"?" ... Food Contaminants and Residue Analysis . Elsevier. pp. 1 –28. ISBN 978-0080931920 . Notman N (2014).
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Schwannomatosis 1
Omim
In 5 (33.3%) of 15 families with schwannomatosis and 2 (7.1%) of 28 individuals with sporadic schwannomatosis, Hadfield et al. (2008) identified germline mutations in the SMARCB1 gene (see, e.g., 601607.0008). ... Although the family data were consistent with linkage of this trait to the NF2 locus, the studies implied that the primary event in the tumors lay outside the coding region of the NF2 gene. In 28 schwannoma tumor specimens from 17 affected individuals in 8 families with familial schwannomatosis, MacCollin et al. (2003) identified 20 different somatic mutations in the NF2 gene, 18 of which were truncating mutations.
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Alcohol-Related Dementia
Wikipedia
The criteria include a clinical diagnosis of dementia at least 60 days after last exposure to alcohol, significant alcohol use (i.e. minimum 35 standard drinks/week for males and 28 for women) for more than five years, and significant alcohol use occurring within three years of the initial onset of cognitive deficits. [2] Oslin proposed the new and refined diagnostic criteria for alcohol-related dementia because he hoped that the redefined classification system would bring more awareness and clarity to the relationship between alcohol use and dementia. [12] Oslin's proposed classification of ARD: Definite alcohol-related dementia At the current time there are no acceptable criteria to definitively define alcohol-related dementia. ... Significant alcohol use as defined by a minimum average of 35 standard drinks per week for men (28 for women) for greater than a period of five years.
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Goitre
Wikipedia
The Bavarian tracht in the Miesbach and Salzburg regions, which appeared in the 19th century, includes a choker , dubbed Kropfband (struma band) which was used to hide either the goitre or the remnants of goitre surgery. [27] Society and culture [ edit ] In the 1920s wearing bottles of iodine around the neck was believed to prevent goitre. [28] Notable cases [ edit ] Former U.S. ... Doctors Say Bush Is in Good Health ^ Altman LK (28 May 1991). "The Doctor's World; A White House Puzzle: Immunity Ailments" .SLC26A4, TPO, TG, DUOX2, SLC5A5, IYD, CLCN5, TEK, TSHR, PAX8, THRB, NKX2-1, DUOXA2, KCNJ10, PIK3CA, POLG, PTEN, KLLN, TRNW, IDH1, TRNS2, TRNS1, TRNQ, TRNL1, COX1, COX2, COX3, ND1, ND4, ND5, ND6, IDH2, FOXI1, SEC23B, SDHB, KCNJ18, AKT1, SLC25A4, CDH23, TWNK, RRM2B, CACNA1S, DNAH1, POLG2, TRNF, SDHD, TRNH, FOXE1, SDHC, GNAS, PTGDS, HT, CCDC6, VEGFA, TAS2R38, RET, PTCH1, F9, TRH, BRAF, MT1A, CCL27, SNX5, FOXD3, ATRNL1, CAD, PRDX5, DICER1, CALCA, CIB1, CD63, NDRG1, MPZL2, KEAP1, RASSF2, LPAR2, SPAG9, PDLIM3, CCND1, CEACAM5, ANGPT1, ACVR2A, MIR222, MIR210, MIR155, ALB, ALPP, WDR62, GLIS3, RBM45, NOX4, FAM83F, CEP78, GRPEL1, ASRGL1, ATHS, BAX, NAT10, SLCO1C1, CDKN1B, CEACAM7, CEACAM3, PTMS, PTMA, PTH, IGF1, IGFBP5, ACVR1B, IL2, PSG2, IL6, PLA2G1B, PKM, CD82, KDR, NTRK1, NCAM1, LDHA, MEFV, MGMT, PTMAP4, HLA-DRB1, MMP2, RGS12, DIO2, TP53, TM7SF2, DPP4, TIMP1, ESR1, ESR2, TERT, TBXT, SST, SPP1, SLPI, FAP, SLC2A1, FGFR1, FLT1, GSN, ABO
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Health Effects Of Coal Ash
Wikipedia
The court ruled that EPA failed to adequately address the problems with unlined ponds, many of which continue to leak into groundwater. [21] In 2019, the court agreed to a voluntary remand while allowing the 2020 compliance deadline for unlined ponds to stay in effect, pending further rulemaking. [22] EPA published a proposed rule on August 14, 2019 that would use location-based criteria, rather than a numerical threshold (i.e. impoundment or landfill size) that would require an operator to demonstrate minimal environmental impact so that a site could remain in operation. [23] In response to litigation on the 2015 regulation, EPA published a final RCRA regulation on August 28, 2020 requiring all unlined ash ponds to retrofit with liners or close by April 11, 2021. ... "Hazardous and Solid Waste Management System: Disposal of Coal Combustion Residuals From Electric Utilities; A Holistic Approach to Closure Part A: Deadline To Initiate Closure." 85 FR 53516 . 2020-08-28. ^ "Revisions to the Coal Combustion Residuals (CCR) Closure Regulations; Fact sheet" .
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Kounis Syndrome
Wikipedia
Proceedings (Baylor University. Medical Center) . 28 (3): 358–362. doi : 10.1080/08998280.2015.11929274 . ... S2CID 32619275 . ^ a b c d e f g h i j k l m Giovannini M, Koniari I, Mori F, Ricci S, Simone LD, Favilli S, Trapani S, Indolfi G, Kounis N, Novembre E (2020-05-28). "Kounis syndrome: a clinical entity penetrating from pediatrics to geriatrics" .
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2018 Amesbury Poisonings
Wikipedia
This went on to state that the investigation into the Amesbury poisoning was ongoing by the Police and the CPS, and further charges relating to Sturgess and Rowley would follow. [27] Inquest [ edit ] The inquest for Sturgess was opened and adjourned by HM Coroner for Wiltshire and Swindon in Salisbury on 19 July 2018, with a Pre-Inquest Review listed for 16 January 2019. [28] [29] This was delayed, in part because the Crown Prosecution Service requested a suspension in view of the ongoing criminal investigation. [30] The Senior Coroner, David Ridley, issued a 31-page ruling [30] on the scope of the inquest on 20 December 2019, but no date for the full inquest was given. [31] Government response [ edit ] On 5 July 2018, Home Secretary Sajid Javid chaired a meeting of the COBR committee to discuss the incident. [32] In the House of Commons later that day, Javid stated the most likely hypothesis was that the Novichok was in an item discarded after the Skripal attack. ... Spire FM . 24 July 2018 . Retrieved 28 July 2018 . ^ "UPDATE: Source of nerve agent contamination identified" .
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Labyrinthitis
Wikipedia
Long-term use of benzodiazapines such as diazepam , however, is not recommended due to the tolerance issues. [25] SSRIs and SSNRIs are among a number of first - line treatments for anxiety or depression. [26] Prognosis [ edit ] Recovery from acute labyrinthine inflammation generally takes from one to six weeks, but it is not uncommon for residual symptoms (dysequilibrium and/or dizziness) to last for a couple of months. [22] Recovery from a temporary damaged inner ear typically follows two phases: An acute period, which may include severe vertigo and vomiting approximately two weeks of sub-acute symptoms and rapid recovery Epidemiology [ edit ] Vestibular neuritis also known as labyrinthitis affects approximately 35 million people per year. [27] Vestibular neuritis typically occurs in those between 30 and 60 years of age. [27] There is no significant gender difference when determining who will get this disease. [27] In 95% of cases, vestibular neuritis is a one-time experience that results in most people fully recovering from it. [28] Vestibular rehabilitation showed a statistically significant increase in controlling symptoms over no intervention in people who have vestibular neuritis. [29] References [ edit ] ^ a b Greco, A; Macri, GF; Gallo, A; Fusconi, M; De Virgilio, A; Pagliuca, G; Marinelli, C; de Vincentiis, M (2014). ... "Vestibular Neuronitis" . Retrieved 2008-06-28 . ^ Martin-Saint-Laurent A, Lavernhe J, Casano G, Simkoff A (March 1990).
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Duane Syndrome
Wikipedia
"Orphanet: Duane retraction syndrome" . www.orpha.net . Retrieved 28 April 2019 . ^ Duane A (1905). "Congenital Deficiency of Abduction associated with impairment of adduction, retraction movements, contraction of the palpebral fissure and oblique movements of the eye". ... University of Washington, Seattle . Retrieved 28 April 2019 . External links [ edit ] Classification D ICD - 10 : H50.8 ICD - 9-CM : 378.71 OMIM : 126800 604356 MeSH : D004370 DiseasesDB : 30810 External resources eMedicine : oph/326 GeneReviews : Duane Syndrome Orphanet : 233 Duanes Syndrome at eMedicine v t e Diseases of the human eye Adnexa Eyelid Inflammation Stye Chalazion Blepharitis Entropion Ectropion Lagophthalmos Blepharochalasis Ptosis Blepharophimosis Xanthelasma Ankyloblepharon Eyelash Trichiasis Madarosis Lacrimal apparatus Dacryoadenitis Epiphora Dacryocystitis Xerophthalmia Orbit Exophthalmos Enophthalmos Orbital cellulitis Orbital lymphoma Periorbital cellulitis Conjunctiva Conjunctivitis allergic Pterygium Pseudopterygium Pinguecula Subconjunctival hemorrhage Globe Fibrous tunic Sclera Scleritis Episcleritis Cornea Keratitis herpetic acanthamoebic fungal Exposure Photokeratitis Corneal ulcer Thygeson's superficial punctate keratopathy Corneal dystrophy Fuchs' Meesmann Corneal ectasia Keratoconus Pellucid marginal degeneration Keratoglobus Terrien's marginal degeneration Post-LASIK ectasia Keratoconjunctivitis sicca Corneal opacity Corneal neovascularization Kayser–Fleischer ring Haab's striae Arcus senilis Band keratopathy Vascular tunic Iris Ciliary body Uveitis Intermediate uveitis Hyphema Rubeosis iridis Persistent pupillary membrane Iridodialysis Synechia Choroid Choroideremia Choroiditis Chorioretinitis Lens Cataract Congenital cataract Childhood cataract Aphakia Ectopia lentis Retina Retinitis Chorioretinitis Cytomegalovirus retinitis Retinal detachment Retinoschisis Ocular ischemic syndrome / Central retinal vein occlusion Central retinal artery occlusion Branch retinal artery occlusion Retinopathy diabetic hypertensive Purtscher's of prematurity Bietti's crystalline dystrophy Coats' disease Sickle cell Macular degeneration Retinitis pigmentosa Retinal haemorrhage Central serous retinopathy Macular edema Epiretinal membrane (Macular pucker) Vitelliform macular dystrophy Leber's congenital amaurosis Birdshot chorioretinopathy Other Glaucoma / Ocular hypertension / Primary juvenile glaucoma Floater Leber's hereditary optic neuropathy Red eye Globe rupture Keratomycosis Phthisis bulbi Persistent fetal vasculature / Persistent hyperplastic primary vitreous Persistent tunica vasculosa lentis Familial exudative vitreoretinopathy Pathways Optic nerve Optic disc Optic neuritis optic papillitis Papilledema Foster Kennedy syndrome Optic atrophy Optic disc drusen Optic neuropathy Ischemic anterior (AION) posterior (PION) Kjer's Leber's hereditary Toxic and nutritional Strabismus Extraocular muscles Binocular vision Accommodation Paralytic strabismus Ophthalmoparesis Chronic progressive external ophthalmoplegia Kearns–Sayre syndrome palsies Oculomotor (III) Fourth-nerve (IV) Sixth-nerve (VI) Other strabismus Esotropia / Exotropia Hypertropia Heterophoria Esophoria Exophoria Cyclotropia Brown's syndrome Duane syndrome Other binocular Conjugate gaze palsy Convergence insufficiency Internuclear ophthalmoplegia One and a half syndrome Refraction Refractive error Hyperopia Myopia Astigmatism Anisometropia / Aniseikonia Presbyopia Vision disorders Blindness Amblyopia Leber's congenital amaurosis Diplopia Scotoma Color blindness Achromatopsia Dichromacy Monochromacy Nyctalopia Oguchi disease Blindness / Vision loss / Visual impairment Anopsia Hemianopsia binasal bitemporal homonymous Quadrantanopia subjective Asthenopia Hemeralopia Photophobia Scintillating scotoma Pupil Anisocoria Argyll Robertson pupil Marcus Gunn pupil Adie syndrome Miosis Mydriasis Cycloplegia Parinaud's syndrome Other Nystagmus Childhood blindness Infections Trachoma Onchocerciasis
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Ataxic Cerebral Palsy
Wikipedia
Typically patients fail to reach motor milestones and show a qualitative difference in motor development. [6] During the neonatal period (first 28 days of life), children are noted to be lethargic, relatively immobile, and floppy. [5] Moreover, hypotonia is greatest during this period, even though muscle tone increases with age, it never reaches normal levels. [5] The limbs show weakness, incoordination in voluntary movement, dysdiadochokinesis (in inability to perform rapidly alternating movements), and titubation . [5] Causes [ edit ] Approximately 2-2.5 per thousand children born in the western world have cerebral palsy, with increasing incidence in twin and premature births. [6] Ataxic cerebral palsy accounts for 5 to 10% of all cases. [7] The cause of cerebral palsy, in particular its ataxic subtype is unknown, but thought to be due to malformation or damage in the cerebellum and its many connections,. [5] [7] The majority of cases that present malformation of the cerebellum are congenital, however acquired ataxic cerebral palsy can result from meningitis, trauma, birth complications, and encephalopathies (septic, acute, disseminated, and toxic). [5] In addition, maternal viral infections may cause damage to the fetal brain due to increase in inflammatory cytokines produced during infection. ... Clinical Obstet Gynecol . 51 (4): 816–28. doi : 10.1097/GRF.0b013e3181870ba7 .
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Sugarcane Grassy Shoot Disease
Wikipedia
The ribosomal DNA contains one transcriptional unit with a cluster of genes coding for the 18S , 5.8S and 28S rRNAs and two internal transcribed spacer regions, ITS1 and ITS2 [17] in eukaryotes, and for 16S , 5S and 23S in prokaryotes . ... Nested PCR assay for detection of sugarcane grassy shoot phytoplasma in the leafhopper vector Deltocephalus vulgaris the first report. (2006). Plant Pathol. 22:25-28. ^ HANBOONSONG Y., RITTHISON W., CHOOSAI C., SIRITHORN P.